Antimalarial Drugs (Part- 06)= Mechanism of Action of Quinine | Quinine Mode of Action in Malaria

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Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes.
Malaria is caused by single-celled microorganisms of the Plasmodium group.The disease is most commonly spread by an infected female Anopheles mosquito. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of Plasmodium can infect and be spread by humans. Most deaths are caused by P. falciparum because P. vivax, P. ovale, and P. malariae generally cause a milder form of malaria.
The signs and symptoms of malaria typically begin 8-25 days following infection, but may occur later in those who have taken antimalarial medications as prevention. Initial manifestations of the disease-common to all malaria species-are similar to flu-like symptoms, and can resemble other conditions such as sepsis, gastroenteritis, and viral diseases. The presentation may include headache, fever, shivering, joint pain, vomiting, hemolytic anaemia, jaundice, haemoglobin in the urine, retinal damage, and convulsions. In the life cycle of Plasmodium, a female Anopheles mosquito (the definitive host) transmits a motile infective form (called the sporozoite) to a vertebrate host such as a human (the secondary host), thus acting as a transmission vector. A sporozoite travels through the blood vessels to liver cells (hepatocytes), where it reproduces asexually (tissue schizogony), producing thousands of merozoites. These infect new red blood cells and initiate a series of asexual multiplication cycles (blood schizogony) that produce 8 to 24 new infective merozoites, at which point the cells burst and the infective cycle begins.
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[@pharmacistaltamashansari6668]

Score 10/10, nice explanation sir,sir ek request hai apse jo online test hota hai har part per questions ban rahe hai jab ye topic complete hoga to en sare questions ko combined karke test lena jisse antimalarial topic complete revision Ho jayega hum students ka,we students are proud of you sir.

[@solutionpharmacy]

Great idea. But all students are not raking that much interest and for me its getting very difficult to manage all. I am not getting proper support by students. I have limited resources to share and i need max share then only my new online test seriese will reach all students. I am alredy working in compiled paper but how i will inform all. It will only possible if students share our motto.

[@mirzaasfak]

Yes sir it will very effective for us

[@AbdulBasit-hk1wh]

Sir what is the difference between choloroquine and quinine MOA

[@vrijendra_maurya100]

Thank you so much sir❤❤❤

[@farazsardar575]

Sir me ne abi lecture suna nahi hai lakin i know ap buht experienced teacher hai ye video be baqi videos ki trh bht hi nice hogi or buht achi trh se ap ne smjae hogi... Mere liyay pharmacology buht tough subject tha lakin ab ki videos ne mje bht hi zyada madad di hai kafi had tk me smj gaya.. Thank you so much sir.. Love from pakistan❤❤❤

[@solutionpharmacy]

Thank you so much for such a great love and support

[@007.shailendrakaushik7]

Mechanism of action become so Easy....it help me a lot Sir

[@solutionpharmacy]

Aage ke parts aur pahle ke parts delhiye hain usme MOA

[@umeshtyagi3160]

Sir aapki video hmesa best hoti hai, good explanation sir👌

[@parikigallerys2105]

Thank you for ur tough work for us.. Providing that much facility(test) ..nd the way u r explain everything and each point with repetition of terms meaning... Thank you sir.. Scored 10/10😇

[@solutionpharmacy]

Great. Thank you for your feedback

[@suntuzuki5753]

Thanks sir providing best trick for study

[@solutionpharmacy]

My pleasure

[@rajamanhar5914]

9/10. Sorry sir ish baar 10 me 10 laounga. Thank you SO much sir.

[@solutionpharmacy]

Raja Manhar koi baat nhi hota hai. You are the honest one. Good

[@mrunalimayekar4943]

Sir, your videos are very helpful Thank you so much ☺️

[@solutionpharmacy]

My pleasure.

[@shubhamkalkhaire2828]

Sir wo konsa specific enzymes he Jo hematin to hemozoin me convert karta ...? Guinine use enzymes ko inhibit karta he na..

[@vibhapatel7918]

Thank you sir

[@pratibharajpurohit4406]

Thanks..sir for giving your 💯% effort for us.

[@solutionpharmacy]

My pleasure

[@NehaKumari-ie7jw]

9/10 Thanku sir

[@solutionpharmacy]

Neha Sone good one. Yes you have made mistake in quinin mechanism of action.

[@uvsagu7]

Nice leacture sir ji 🙏🙏🙏

[@solutionpharmacy]

Uv Sagu thank you

[@poojabadve7777]

Thank you so much sir...very nice explanation...🙏

[@solutionpharmacy]

Thank you

[@devakanna7319]

Thank you sir, finally I too got 10/10, very helpful, thank you soooooo much for your selfless effort,

[@solutionpharmacy]

Nice score. Keep going

[@anuragbhatt8916]

Excellent sir

[@solutionpharmacy]

Thank you

[@shaguftakhanam1273]

10/10...... thanks once again Yesterday I asked u about from where I can start your lecture....and u replied me in which SEM am I.........so the answer is I'm not student of pharma sir...,,,😐 Actually I had completed my bsc(general science) and also BUMS (bachelor of unani medicine and surgery) in unani college there is a small part of pharmacology so it's like all about negligible I had book k d tripathi which was never learned by me.....😔 And now I'm out of India last 7 months so this pandemic tym I have to live in home am completed internship October 2019 So I want to use my tym in some knowledge way not in movies or drama....etc.... I think this tym is use here....and lastly one problem I don't have any medical book here not even k d tripathi Oohh it's become soooo lengthy sorry I hope u understand my situation

[@solutionpharmacy]

Yes i can understand your issue. And really i am happy to know that you are excited to use your time in study. Please go to playlist of - Pharmacology for MBBS and watch the videos feom there as per sequence if you have time

[@shaguftakhanam1273]

@@solutionpharmacy thank you so much

[@joshilayvlogs]

Sir please give details on hemalrin syrup

[@luvkumarkashyap2022]

Thanks you sir..👍

[@solutionpharmacy]

Most welcome

[@23-anujasunilchavan45]

Sir aap jo ye lecture mai sab lete ho white board section ... Isn't it sufficient for gpat exam also.... .. Can we score qualify marks in gpat... On basis of this???

[@solutionpharmacy]

These are very important along with GPAT Exclusive playlist. Many students got selected in GPAT via these. So if will watch honestly you will get benifited

[@23-anujasunilchavan45]

@@solutionpharmacy thank you so much sir..... Yess sir i can watch all videos completely

[@archanakumbhar2060]

Thank you sir 😊😊😊😊 my score is 8/10

[@solutionpharmacy]

Good one

[@cricketanalysisbyankit5170]

8/10 sir such a wonderful experience

[@solutionpharmacy]

Thank you. Good score

[@ShivaniNayak-r8e]

Sir apne kha ki quinine p. Vivax ko kill krta hai pr p.vivax hi to relapse cause krta hai hai to ye hypnozoits pr effect kaise show nhi krta hai

[@bhoopendragupta9947]

Does quinine sulphate 300mg causes hearing loss For how many days

[@neelamyadav5052]

Thank u sir 10/10 score nice lecture

[@solutionpharmacy]

Very nice

[@rhsarlahiwala7347]

Other use and ADR different in this lecture or same please explain sir

[@solutionpharmacy]

Means ??

[@qclaborganization9006]

Xilent lecture Sir

[@solutionpharmacy]

Thank you

[@shashikantkumar3683]

Thank you sir score 8/10🙏🙏🙏

[@solutionpharmacy]

Good

[@Suriddha_Munshi]

10/10..thank you so much sir😊

[@solutionpharmacy]

Suriddha Munshi you are so inteligent

[@Suriddha_Munshi]

@@solutionpharmacy it's just only because of you

[@payalhumane3674]

Thank you very much sir ,score 10/10🙌🙌

[@solutionpharmacy]

Payal Humane great

[@-BhadoriyaMohitSinghN]

Sir aap kis acidic condition ki baat kar rahe hai ? RBC ki ya Food vacuole ki

[@solutionpharmacy]

Food v

[@rhsarlahiwala7347]

Other effects and ADR are same or different in this lecture.

[@solutionpharmacy]

Almost same

[@rajuryadav7972]

Score 9/10 thank u sir

[@solutionpharmacy]

RAJU YADAV good one

[@shuvadipbhowmik7632]

10/10.Thank you sir.sir agar apko time mile to kya ap medicinal chemistry ke upor video banayen ge?? Kiun ki sir ap bohot a66a explain korte hai.sir mujhe pata hai ki ap akele ke lia muskil hai video banana and editing korna do subject ke lia ak sath ma.sir fir bhi agar ho sake to sir bohot hi a66a hoga.sir please🙏🙏🙏🙏

[@solutionpharmacy]

Shuvadip Bhowmik i am ZERO in chemistry thats why i have choosen this cology as my subj.

[@shuvadipbhowmik7632]

@@solutionpharmacy That's your humble opinion sir.

[@mirzaasfak]

@@solutionpharmacy you r a great Teacher for cology. U make it very easy. Love u sir

[@avijitbej2683]

9/10 Thank you sir❤️. Sir, what will be the online test of the previous lacture?

[@solutionpharmacy]

Avijit Bej welcome. Sorry its not possible for me right now but it will come later

[@avijitbej2683]

@@solutionpharmacy ok sir

[@dashrathmali1750]

10/10 TQ ❤️❤️sir

[@solutionpharmacy]

Good

[@abhinavpharmacy7503]

TQ sir 9/10...

[@Ravindrashah1236]

Sir marks 9/10

[@solutionpharmacy]

DRx Ravindra shah good

[@swethavemula7996]

Sir as hematin is a toxic substance n it kills the parasite...is it also toxic to the RBCs ??

[@solutionpharmacy]

RBC is not having metabolism organ.

[@swethavemula7996]

@@solutionpharmacy ok sir 🙏

[@zulfaabdulnasir]

Scored10/10 🥳 ✌️...

[@solutionpharmacy]

Zulfa Nasir v nice

[@meenasaxena1600]

Good evening sir sir kya b.pharma complet student clinic open kr sakte h ager kr sakte h to kese iski bhi informetion uplode kriye

[@solutionpharmacy]

Abhi iski koi clear info nahi hai

[@anushrikudatarkar1527]

9/10 thank you so much sir 🙌

[@solutionpharmacy]

My pleasure. Good score

[@vibhapatel7918]

Thank you sir for score 10/10😊

[@solutionpharmacy]

Good

[@goldylive8661]

Sir please upload Stretergy video on gpat🙏🙏🙏🙏

[@solutionpharmacy]

We are related to theory

[@titikshakumarsagar568]

Sir, please tell us the estimated date when will be pharmacology 6th-semester syllabus will be over.

[@solutionpharmacy]

Titiksha Kumar Sagar sorry i cant forcast it but may take around 2 monrhs

[@lakshaykapil439]

Sir How we remind drugs name.. Sir because their is to. Much drugs in pharmacology so plz sir give some ideas or any shortcut to remind all these drugs 🙃

[@solutionpharmacy]

Please check playlist. I have uploaded mnemonics to learn this

[@sajidahamd6412]

Sir , can I write down on his institutional exam paper , While this question bring in 7 mark Will this much write in enough If any fault in word or sentece Please sorry

[@solutionpharmacy]

Yes

[@desizooster1994]

Today I got 9/10

[@solutionpharmacy]

lokesh yadav Yadav good one

[@rahultamang8324]

I got 10/10

[@solutionpharmacy]

Rahul Tamang v good. All the best

[@suntuzuki5753]

Sir I obtained 9 marks

[@solutionpharmacy]

Good

[@suntuzuki5753]

Thanks sir

[@prachisinghkashyap8471]

10/10

[@solutionpharmacy]

Good

[@pratapchoudhary9893]

Sir part pura hone test lete ho ..... lekin topic pura honne prr bhi ek test le liya kron 50-100 Q kaa🙏🙏

[@solutionpharmacy]

Wo bhi hota hai. Last part me dekhiyega

[@samikshashetye9486]

Sir... Aap dusre pharma subjects par videos kuy nahi banate???

[@solutionpharmacy]

Samiksha Shetye Aap to admission lete hi digree milne ki ummid kar rahi hai. Abhi channel start hua hai aur dheere dheere subjects aayenge jo mere exertee ke hain. I cant teach every subject

[@samikshashetye9486]

@@solutionpharmacy sir gpat ki taayari aache se hoti agar aap dusre subject padate.. final yr me hu.. bademe tho koi fayada n hojayega

[@solutionpharmacy]

Samiksha Shetye Delhiye hum to sabhi subj ke expert nhi hain aur na hi ek saath sab subj bana payenge aur fir ye videos sirf aapke kaam thode aayenge ye to aane wale samay me sabke kaam aayenge. Ye kisi ek ke liye nahi ban rha sabke liye aur sabhi samay ke liye.

[@samikshashetye9486]

@@solutionpharmacy ok sir .. I Just want to thnkuuu fr explaining so well ❤️🤗

[@samikshashetye9486]

@@solutionpharmacy sir .. ek sawal hai kya aap gpat ke exam ke prepartn par koi tips yaa question series de sakte hai?

[@aannajarvis4188]

Sir antitrypanosomal please

[@rajivdas8185]

Seen

[@dipakparmar1793]

Sir bija vidieo na pan msq banavo ne thay sake to

[@solutionpharmacy]

Kya ?

[@dipakparmar1793]

@@solutionpharmacy online test sabhi vidioe ki ho sakti he kya?

[@solutionpharmacy]

Dipak Parmar aane wale video ke liye

[@70pradeepyadav5]

It's not giving acees to give the test.

[@solutionpharmacy]

Pradeep Yadav no there is no problem. Recheck

[@devakibhadi1999]

Very poor scor 5/10

[@solutionpharmacy]

Devaki bhadi please listen video seriously. You will do v good soon. All the best

[@omkarsheelvanth8258]

Thank You so much....Sir

[@solutionpharmacy]

Omkar Sheelvanth my pleasure

[@SatishYadav-ld1cs]

Thank you sir

[@solutionpharmacy]

My pleasure

[@basirshaikh247]

Thank you so much sir

[@solutionpharmacy]

Basir Shaikh my pleasure