MHC class 1 and 2 | Major histocompatibility complex

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Really you are greatest then books and professor which I came across

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Yes this is pure beauty

[@Teja.official]

this..is probably the best explanation of MHC... complex....🙏🙏🙏🙏

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[@shifafasmin5961]

Helow sir,am a microbiology student n i prepared my notes by listening ur videos n it really reallyy helping me a loottt..!!Thnkyeww so much🤗

[@suparnomukhopadhyay7466]

When you don't understand the topic come to youtube and write the topic and then shomu's biology and you get your ans... really good content with nice conceptualizing,thank you sir🙏

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[@tanmaybhattacharya5864]

This video is-"A complex topic in a easy way"❤️❤️❤️...I read in physiology but in immunology I have a huge problem to understand MHC like it's name "major complex"..but in this 20:25 I understand the whole thing... thank you so much....

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[@WanrisaWahlang-s2d]

Almost a week i study this topic but still i don't know anything I start to lose interest on studying.....but watching this video it really help me and inspired me to study again, thankyou so much sir for your explanation 😇

[@lucilaalvarez4095]

Thank You Shomu. Im surviving med school thanks to you!🙏

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[@DebayanGhosh-zn7cl]

It's ok lucila

[@maksull]

I agree with many of the other comments -- the content here is made exceptionally clear. Example, no one ever explains the damn name: Major Histocompatibility Complex -- in terms of graft/ host. Your body is using MHGs to check whether the tissue (histo) is compatible with you/SELF. This is but ONE function. He explains this, and also how only the macrophages, dendritic and B cells possess the MHC2 receptor -- its all made so clear in a way that keeps looping back to the overall picture of the immune system. Congratulate Shomu, and yourself for finding him! He seems to really love the subject and this is contagious.

[@ROYSJOURNEY]

Sir Seriously as you are teaching no one can.. Great effort sir.. From class 11 I am watching yr videos and now I am in 2nd Year seriously the journey was aswome.. and will be.. Thanks a lot.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts. Stay tuned for more. I am glad to be helpful. Wish you all the best for future career

[@norhlengurung4208]

Hellow sir ; I'm a medical student I wanted you to know that your videos are really helpful and you make it so simple to understand . Thankyou

[@sumbelgulaly8354]

The guy who helped me throughout my intermediate and still helping in MBBS .. but i do have a request plz make biochemistry videos for MBBS specifically those topics which u haven't done.

[@shomusbiologyofficial]

Sure. Glad to hear that you're getting benefit from my lectures

[@mazzucchettiianmateo3188]

congratulations, this is the best video about MHC and immunology that I've found, just continue like this charging material, your channel is great!!!!

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[@joshuaeskelson4794]

Thank you Suman Bhattacharjee! Always love your videos and it makes my immunology and molecular cell classes easier to understand.

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[@gyanendrakumar8183]

So easy to grasp everything to even a non biology student...thank you.

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[@dikshaneogy6414]

Your lectures have always been helpful for getting a clear understanding of the topics right before the exams. Thankyou ☺

[@yaminijoshi9435]

Sir u made this complex topic so easy.....ur whole series of immunology can build up one's concept......

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[@vivekyadavkm5307]

Very easy to understand Ur lecture sir I completed my bsc in microbiology and MSc in microbiology from Ur lecture keep going lots of love from Karnataka ♥️

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[@hudanoor8979]

Thank you sooo much SIR u make my life easier. I always come to watch your videos when i am facing problems, everything is simplified love it !!!!!!!!!!

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[@vijithaa]

Wow very clearly explained. I'm preparing for my PG NEET and your videos are making me strengthen the basics. Thank you 😊

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[@SheikhAshiq768]

Bro what a knowledge you have, it really motivates me the way u are understanding

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[@kbunawab2870]

Still learning from these lectures Helpful teacher for biotechnology students ❤️

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[@subalakshmisankaran1285]

Beautiful sir. Lots and love and respect😇. Ur my inspiration. Ur explanations are clear and crisp. Helpful when we feel to learn immunology with interest. Wishes from Chennai, Tamil Nadu

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[@vaishnavipathak4988]

Immunology became easier.... thank you🙏

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[@sakshimishra5138]

It's a proper deep knowledge about MHC molecules... thank you sir for providing this video for us 😊

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[@manishjangir4790]

Fabulous sir....really sir I have never seen such a way to represent things .......hats off to you sir... literally I gotten fan of you as you simplify and describes things ❤️❤️ Sir I too want to be in lecturing field n you know what I will be exactly like you ...I mean all of your qualities and skills .....all I m saying is you are my ideal sir.....❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️

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I appreciate your videos! They've helped me alot in my exams. Thank you and keep it up

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thanks a lot.i understood more from u than from my professor

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[@robinbhuiyan244]

Bhai, just lovely !!!!!!!! we need more video on MHC because my PHD completed teacher is not better than you, really bhai

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@@shomusbiologyofficial its not just benefit, your video is also like one type of property for me..... you are most wlcm Bhai

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Your better than my professors in Medical School. God Bless you:) You are incredible.

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The way you have taught in immunology lectures is really appreciating. Thank you so much sir.

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[@salehaqadri96]

I just Love you shomu🥺🥺💖 u make things so simple... these immunology questions were appearing like a bull with two horns ready to kill me😵😵but Almighty bless u ...u made it so simple....again tysm for u lectures...plz keep up the good work 🥰🥰

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like metabolism reaction, every complex things become simple after seeing your video classes

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Best teacher I found

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Your videos are one of the best for Microbiology. Thank you

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+Alicia Amiri glad to hear that

[@bhukyarajesh1280]

Sir really you made complex topic to easy Sir.Thank you So much Sir

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[@sunitamishra4698]

these are really helpful videos to learn basic concepts... the language used is really simple.

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This video has been of great use time,thanks

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[@punkkauz]

Very nice video. I could understand simply by being on a running machine. Wow..

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[@miloblue6740]

Loading of antigen onto MHC class 2 does not occur in the ER and does not require the proteasome, however loading onto MHC class 1 does require a proteasome and does occur in the ER but it is not for pathogens that have been engulfed from the extra cellular environment, that mechanism is for pathogens that replicate within a cell and thus there is no need for an uptake stage during antigen processing. Please correct that mistake.

[@miloblue6740]

Clip replacement occurs in the cytosol and it occurs with the help of HLA-DM. It does not occur freely and randomly as explained in the video.

[@Alic_R1]

THANK YOU, I was thinking that the video explanation was wrong.. but then I looked at my own notes describing what you say as well... Yeah it's a mistake in the video.

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Bffelim

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Thankyou so much sir….you are really helping me to understand concepts through ur lectures!!👍

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Sir ur concept of explaining all topics is so easy and good😊👌thankyou sir.

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Thank you soo much.. Its very easy to understand and to take notes more than my med school lectures..

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Your All Videos Is Very Helpful for me ... thanks.

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I can't tell u .. how much this helps me 👍 I loved it .. I love science ❤️

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@@shomusbiologyofficial how do I reach your insta ?

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Thank you so much sir! It was extremely useful for me as a medical student🙏🙏

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I like your accent and hair style Shomu :) And thank you so much!

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You are incredible. I am fully dependent on your lectures.

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@@shomusbiologyofficial Thanks to you for delivering such incredible lectures to us. I subscribed your channel on firstday i watched your lecture. Take care

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thats a mind blow lecture, really helpful, I have histology exam tomorrow, gonna check out the rest vids to help me.

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+Abood Nero (VampireForces) great. Glad to know that

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Thankyou sir your videos always clear my doubts.

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Absolutely fantastic lecture.

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very helpful... u r best teacher...

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+Alwina Anam thank you Glad you liked my lectures

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you made me understand better than my teachers bruh ty

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Sir,we need more detailed lecture on immunology in context of MSc batch

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Best teacher ever shamos sir from pakistan...

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Many thanks 🌹 God bless you 🌹 you are the best 👍 definitely

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Very helpful lecture...thankyou so much sir,u r the best teacher😊

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I swear u best than our teacher THANK U really!! u helped me a lot!

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+Shaden Alhathloul glad you liked my lectures

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Amazing explanation loved it!!

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Very well presented and accessible, thank you.

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Very well presented

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You’re amazing . Great video . Your helping me so much.

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Thank you so much sir for ur effort 😊❤

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thanks very helpful.. I pray ur videos flourish more n more....

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Great demostration sir...🙏

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Thank you so so much sir for our concepts so easy 🙏🙏

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I watch your tutorials and just write and pass my exams💕

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Glad it helped

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Thank you Sir ,for such a wonderful explanation.

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[@md.sharifulislamswapon2685]

Great explanation

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Thankyou so much sir!!🙇🏻‍♀️

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As always, the best!

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Thank u so much sir 🙏 for your videos through your videos it is easy way to memorize everything best teacher 😄

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[@shreyamishra08]

Sir I need ur help in haptens and epitopes so can u help in this Two more topics

[@daniyalyounas9455]

It is very helping most of the time your lecture help me more than my teacher's lecture😅😅

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@daniyalyounas9455]

@@shomusbiologyofficial would you plzz recommand me any book about the MHC classes?

[@bhawanisharma2407]

@@daniyalyounas9455 go for immunology by kuby

[@btchhangte4481]

Interesting video... Could you please explain Protein kinase R 🙏

[@shomusbiologyofficial]

Okay

[@sawanbhardwaj8742]

Great explanation sir ❤️ thanks

[@shaguftajabbar1768]

You're a great teacher, Thankyou!❤

[@shomusbiologyofficial]

You're welcome

[@sreyadas9272]

Concept clear❤

[@shomusbiologyofficial]

Thank you

[@ankitabanerjee4726]

hello sir, thank you for making such useful videos. I am a pharmacy post-graduate, who do not have such in-depth knowledge of life-sciences. I just have a request to you to make video keeping in mind about us also. though I am not from pure life- science background but preparing for NET for PhD. Help students like us. Thanks and warm regards.

[@ayushichoudhary192]

U r amezing ❤️❤️ literally nice

[@shomusbiologyofficial]

You're welcome

[@supriya.0296]

Better Class Sir

[@shomusbiologyofficial]

Thank you

[@Simi.g]

Thank you so much for making us understand the topic so well. You are just amazing . One thing i was curious to ask while watching the video was, that means these MHC complexes are not present on the cell surface all the time , and only if the pathogen is recognised , the ER will release the MHC complex bounded with pathogen. Is it so ?

[@gautamsinha8086]

Sir one request plz sir upload a video on endogenous antigens :the cytosolic pathway

[@renasisa6522]

Amazing as usual. Thanks

[@shomusbiologyofficial]

+Renas Isa you're welcome

[@aishah7787]

I’m really thankful for you

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Thanks so much Dr

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Thank you so much ,today is my exam

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[@komalmane775]

Please make a video on antibody production

[@n.dcreations2805]

Superb explanation thank you sir

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Sir you are so helpful..

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Thankyou so much🍃

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[@acttalksh7458]

I like ur way to teach

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Man I love your videos!❤️

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Thank you

[@misbahmalik2998]

So nice sir.

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Thank you

[@feosportshd2262]

Concept clear hua thank you sir

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[@NoorHidayat973]

U r the god father for the biochemistry students

[@sanketthecuber5607]

simple words OP🔥🔥

[@rusulsalih8393]

thank you very much your explenation very clear.keep up the good work

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[@Mou48u]

Darun🎉

[@shomusbiologyofficial]

Thank you

[@nourinparvej9601]

Plz make a vedio on MHC restrictions and co-stimulatorysignals

[@Talentcreationndimagination]

Sir aap my best teacher ho

[@shomusbiologyofficial]

Thank you