B cell activation and differentiation

[@raymondadomako8165]

Shomu is a legend. U deserve a Nobel prize for exhibiting unique and most active teaching skills. We are grateful

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@khawajaasadhusnain7849]

I agree he deserves

[@khawajaasadhusnain7849]

Itna asan Method Kisi Ka Nai Hay

[@Qwerty133g]

Agee but thoda jyada ho gya

[@AliRaza-ly3nn]

​@khawajaasadhusnain7849😂7p6

[@dustybins7027]

BRUH, you're better than a lot of my medical school professors from the states!

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@MK-xw8do]

u r d saviour during our exams ...ur videos are outstanding

[@shomusbiologyofficial]

+manpreet bagga thank you. Glad you liked my lectures

[@medharao2539]

@@shomusbiologyofficial u explain so well sir thank u so much for ur excellent explanation

[@lorib5323]

Thank you so much for these videos. I love my teacher, but I can't hear or understand him very well. :) With your videos, i can start, stop, take notes and repeat if necessary. I had no idea what my teacher was talking about when he went over T & B cell interaction and activation. Now I do! Thank you!

[@simpilal8094]

Ur videos r of immense help. God bless u

[@wild23oo]

Subscribe me i am making hand tutorial biology

[@rebeccacarissa9381]

i don't usually leave comments but the way you teach is very engaging and clear!

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@dawnhoran3353]

Another brilliant lesson by the most amazing tutor on youtube, thank you.

[@shomusbiologyofficial]

+Dawn Horan thank you. Glad you liked my lectures.

[@harmandeepkaur9641]

This is my first comment on KZbin..just wanna say m a fan after watching these immunology lectures..😊

[@TheGhost-lm1xp]

U are the first indian doctor that I can understand his videos❤️love from Iraq

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@FluryTheMc]

Nicely explained. You have great teaching skills. Greetings from Switzerland

[@shomusbiologyofficial]

Thank you

[@Austin-v7t]

Reading notes that provided by teachers are so difficult. But it is simple explanation i have ever heard

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

[@adamxenon2127]

cant tell how grateful i am watching your videos, understanding stufs from your videos is just systemic and i love that. thank you

[@SaraKhan-xr6jv]

So many students are blessed with your Detailed explanation. Thank you sir

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@pranzaldass]

A teacher should be like you. you're unique.... love from assam❤

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@shatavisasardar9162]

You teaching process is so beautiful that I understand every difficult thing very easily.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@sammaya8355]

Hi sir, I am a student from Belgium I juist can't thank you enough!! Before my exam I juist watch your video's and I have 98%. thankxx alot!!!! My advice to all students...watch these video's before you start reading your book I am 100%sure you will understand better

[@71avis]

Thank you i did a paid course at udemy (fundamentals of immunology) but ended up here.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@drashtijhajaria4407]

Thank you Sir for making our studies simpler and interesting.

[@marianavilela1376]

Thank you so much for this. I learned a lot. I love the way you teach so enthusiastically.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@vidhipandya6488]

your videos are short and full of information. among all the videos have watched, u r the best till now.. thank u.

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos. Please subscribe and share

[@kritikasaini5902]

you are amazing . i all ways study my immuno. and biochem. from your videos and it increase my knowledge every time.

[@keitumetsedorothy4020]

I’ve been watching your videos since 2017😭😭always helpful ❤️

[@Khushboo-ei9wx7nq8e]

Best teacher ever ....u made such topics so easy that any one can understand....

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@Ankitsingh-dw3vs]

No words to appreciate you sir.... Thanks alot for clearing my doubts... Your contents are much sufficient to get good knowledge about immunology in veterinary science also 😊

[@shomusbiologyofficial]

Thabk you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures

[@labscience97]

You are superb bro..the main point is you have the key points,and u describe those very clear as water..im mls graduate from 🇱🇰 ,

[@SouravsAcademy]

U are my real inspiration.. After watching ur dedication and hardwork, i feel that u r a great teacher... I also came to KZbin platform after getting inspiration from u... Hope one day biology family also feel proud for me..

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

[@SouravsAcademy]

@@shomusbiologyofficial i am doing graduation in zoology and have a dream to crack csir net... I have also a channel on biological Sciences... If u check my video one time and give me some suggestions in comment it will be very motivate for me

[@gazalatariq4193]

Great sir...no words to explain how easy you made it...thnx...

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@alistyair]

I dunno who you are, and where you came from... but that was the best 14 min detailly well explained Immunology! Thank you saviour🙏

[@disharanjan1361]

U r really very talented..and expln everything in so easily..tysm for being a life saviour ❤️

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@homophobe6250]

freaking indians

[@sstarstruck9495]

Loving your videos. Just pulled an all nighter going through all the videos of immunology!!

[@kadyrgulykadyrguly9456]

ohh myy gusshhh its veryyy understandbleee veryy useful i wish you success in your life professor

[@nishavijayasarathi101]

Thanks shoumu your lectures are very useful for people to preparation of exams.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@abed031]

great teacher who makes the biology in our hands..

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@conceptualmedicos9317]

you are great...Teacher from unknown place.. Thanks of your every single word you teach me..

[@Sakti-i8m]

First 2 things is there 1) thymus dependent 2) thymus independent 1. Thymus dependent 3 signal is there 1. BCR binds with AG and internalization (endocytosis ) those AG have spliced The MHC molecule identified and externalization of MHC molecule. And bind with TCR and CD 21 complex activation occurs (CD 21 (c3b,CD 19, CD 81) receptor activated in B cell and downstream signal activated B cell differentiation occur. 2 signal CD 40 bcell / CD 40 L ( T cell) (b cell cell division strated produced B cloned cell ) activated SHM ( somatic hyper mutation) with help of AID enzyme . And class switching (isotyping ) . This is increasing affinity towards antigen.

[@СергейОганесян-б9ч]

Thank you, your videos are very helpful to understand immune processes!

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures. Please subscribe and share

[@aryaram8192]

Sir....Concepts are so clear with your classes....thank you..!

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

[@jenifer_riya9744]

Soon u will reach 1M .. GOD BLESS YOU

[@shomusbiologyofficial]

Thank you

[@smartkids9007]

i got position in m.phil studies just because of you thankyou so much sir:)

[@ashleywhitaker7963]

you do such an amazing job at explaining! You're great at what you do!

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@riniparvin5541]

Thank you shomu da.... Whenever I found any problem...I use to watch your videos.. thnx a lot da

[@shomusbiologyofficial]

Glad to help you out. Please subscribe and share

[@riniparvin5541]

Subscribed from 2017

[@romanww1479]

Your structure is very clear. You can underline important gist very well

[@ananyachatterjee7366]

Thanks a lot Suman Sir...for gifting us such excellent videos which are very helpful for understanding those topics clearly.

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@sadiyohassan2314]

OMG you save my time and learn more I wish my teacher should just explain this simply thanks alot and God bless you

[@suruchiburma1926]

u r a blessing 4 d students sir..rely these videos helping me a lot.

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@starzoologyclasses7561]

your language is easy to understand,thank you

[@shomusbiologyofficial]

You're welcome

[@justsomebakahere]

Thank you for being here for us students, your videos are really helpful

[@sasmitadas8254]

I can learn and understand more things through ur videos. It will help me in my exams.

[@rashmiranjanparhi5634]

Loved it bhaii... YOU SEEM LIKE A POLE STAR in the darkest night....

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@anooptitus6945]

You rock man! Being a doctor, I want to be a great teacher as you!

[@shomusbiologyofficial]

+Anoop Titus thank you. Happy to inspire

[@saistabano78]

Thank you so much sir for the best videos. these are very helpful to easily understand whole process. your teaching is amazing

[@Athena7_7]

I cherished a hope to meet u, brother... U help us a lot.. Take respect from Dhaka, Bangladesh

[@gulshanzahara1990]

interesting videos and understandable videos,,,, thank you very much sir u have magic of teaching biology,,,,

[@shomusbiologyofficial]

Glad you liked my lectures

[@shakilahmadkhan808]

Loved it man confused on this concept since a long time u helped me out. Thank u so much. 👍🏻😇🤞🙏🎉

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@shakilahmadkhan808]

@@shomusbiologyofficial is it ok for neet level.???

[@ranjitsbioconcept6264]

Excellent lecture .... Thank you Sir ,, your starting music is awasome ,,, this music brings a current in my body

[@shomusbiologyofficial]

Glad you liked my lectures. Thank you

[@prabirmondal2089]

Greatly explained everything, every portion

[@shomusbiologyofficial]

Thank you

[@violinakalita7896]

u r my last option surviver ...thank u sir!!

[@sewanasradin3248]

Loved teacher thank you you made my exam easier 🌹🌹🌹

[@shomusbiologyofficial]

You're welcome

[@ankitakhole4885]

Thank you so much for your lessons, its so helpful and understandable. Thank you for making science simple to understand😊 Much respect sir.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@bensmainebensmaine7635]

thank u so much sir ......greetings from Algeria

[@shomusbiologyofficial]

Thank you

[@sapnashandilya2276]

thank u sir..i always see ur vedios whenever I confused in any topic ..ur vedios helped me so much regarding any type of topic of biology

[@komaldiptianandmaisuriya4301]

You are the best..we understood it so well

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@divya_264]

Thankyou so much sir. Sending lots of best wishes.

[@shomusbiologyofficial]

You're welcome

[@ajitdardare4565]

How can you store that lot of information in your mind how ?? Thanks bro, I was watch your video 2 years left you are awesome and literally so easily learnt about a critical concepts so thanks once again keep it up😊😊😘

[@lakshmisundararajan6031]

OMG ur video is sooo clear... Thank you

[@shomusbiologyofficial]

You're welcome

[@navyanandhanaofficial]

Really wonderful teaching. My Request is to show the whole diagram at the end of the video.. it will help peoples to recollect all the points once again. Thanks

[@VijaySingh-zs9wo]

i am learning a lot of from your videos sir thanks so much plz keep uploading more videos

[@shomusbiologyofficial]

+Vijay Singh thank you. Glad you liked my lectures

[@anaghapradeepan5409]

Thankyou so much for your excellent explanation

[@shomusbiologyofficial]

You're welcome

[@hussainzuhajamz1420]

Thnk u so much sir making it so easy to understand this concept. Keep it up sir👍

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@rakibulhasan9948]

my favorite channel, take love ❤️

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@khushiagrawal4860]

You made it seem so easy today🥺❤

[@shomusbiologyofficial]

You're welcome

[@alwinaanam1231]

ur immunology videos are js too good.......................u r brilliant .............

[@tinatawade8744]

Ty so much

[@juwairiahmazhar9607]

Beautifully explained. TYSM

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@pragyashukla9405]

I luv u sir ,, I'm v judgement al to like videos .. But ur vidoes r just .... remarkably outstanding

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@mansikhandeparkar2764]

Sir your examples are on point and easy ones even for complicated topics. Thank you for this explanation😄

[@revanthreddy617]

Impressive , i dont know which noob hit unlike button , cehck whole video then judge , its a best one

[@bhargabsannyasi5]

Thank you sir only because of you i am passing my graduation exam with good marks

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures

[@shvetarani7586]

Thankyou so much for such precious lectures😊😊😊😊

[@nyamiritut9291]

An awesome teacher, you just made the whole thing simple. God bless you.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@jahirahmed6690]

seeing from Bangladesh, really you are legend brother.

[@shomusbiologyofficial]

+আমরা ইবিয়ান thank you. Glad you liked my lectures. Please subscribe and share

[@fikru3759]

Bro nice example very good and clear explanation

[@shomusbiologyofficial]

Thank you.

[@deeptiology9257]

Thank you Sir.... your videos are so much helpful in understanding complicated topics easily

[@shomusbiologyofficial]

Glad to hear that you're getting benefit from my lectures

[@drfarrah6606]

u r a great teacher, awsome teaching style

[@aparnajangamgari8347]

It's a wonderful explanation sir

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@kunjansilicate]

Superb explanation.. i want you to make teaching on drugs therapeutics.. how drugs choose for particular disease... its side effect.. and monitor

[@abdelrahmanaboudan8767]

That was perfect😮😮.. Thank you so much ❤❤❤❤❤

[@shomusbiologyofficial]

You're welcome

[@anjudaniel3264]

thanks sir .... its really helpful to understand the concept

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@hayatahmed420]

Thank you so much for these amazing explanation. and that means this video is B cell response to T cell dependent antigen right.

[@khadijawaheed1353]

Your lectures are Soo helpful...😊

[@shomusbiologyofficial]

You're welcome

[@ladyarcher172]

Omg, thank you. I just understood in 15 minutes what they tried to tell me in 2 hours lol

[@shomusbiologyofficial]

Thank you

[@Yoji123]

thank you very much!! life gets easy with clear explanation .

[@akashgangan9039]

Thankyou sir for this awesome video lec. All cleared with the Tcell Activation.

[@SKANDHAHAPPYLEARNING]

Legendary explanation

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@menace1782]

He didn't talk about the fact that B cells proliferate once it is activated. This leads to differentiation of two types of B cells: Plasma cells which do the antibody production and memory cells

[@swe1337swe]

Does this proliferation occur after or before the cell modifications initiated by IL4?

[@smartkids9007]

suman brother your new videos are awesome but old one have errors.kindly edit them and upload them again

[@ayushKumar-mk1lk]

shomu u r perfect bio teacher

[@shomusbiologyofficial]

+ayush Kumar thank you very much

[@shomusbiologyofficial]

+ayush Kumar thank you very much

[@trishnanahata4986]

Great video. Thanks a lot. But I am not sure if IgG is present on the surface of B cells.

[@shomusbiologyofficial]

Yes

[@naaznaaz6429]

thanks for such a great information... I always watch ur videos....

[@mafabiambrose8266]

thanks alot .....good stuff for students lyk us

[@fahimalamnobel4789]

thank u very much sir.your lecturs helps me a lot....

[@kart6320000]

B cell receptor is not seprate molecule. It itself is antibody which is membrane bound.

[@shomusbiologyofficial]

I didn't say it's different

[@kart6320000]

@@shomusbiologyofficial hi. at 3:04 you have said BCR are attached to Ab. Actually Abs themselves are receptors for B cells.

[@tashreeqa_ek]

Absolute life saver, thank you so so much

[@shomusbiologyofficial]

You're welcome