Surprise! Your Brain Has a Secret Sewer System

Scientists have found a hidden network in the brain, and it might prevent people from developing certain diseases.
Hosted by: Brit Garner
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Sources:
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.brown.edu/initiatives/wom...
www.ninr.nih.gov/aboutninr/di...
web.jhu.edu/jhnmagazine/spring...
www.ncbi.nlm.nih.gov/pmc/arti...
mcb.berkeley.edu/labs2/robey/c...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.theatlantic.com/health/ar...
academic.oup.com/brain/articl...
journals.sagepub.com/doi/full/...
www.physiology.org/doi/abs/10....
Image Sources:
en.wikipedia.org/wiki/Cerebro...
commons.wikimedia.org/wiki/Ca...
Photograph of Helen FitzGerald Cserr, ca.1970. Unknown photographer. Helen FitzGerald Cserr interview, 2016. Brown Women Speak oral history project, Pembroke Center, Brown University: www.brown.edu/initiatives/wom....
commons.wikimedia.org/wiki/Fi...
en.wikipedia.org/wiki/File:Me...

[@Celeste-in-Oz]

all this time.. had no idea I was being brain washed

[@cingkrimson4719]

CelesteofOz ba dum tsss

[@mrjek01]

CelesteofOz good one.

[@LulitaInPita]

😂😂😂😂😂

[@musiclover6481]

lol 😂😂

[@ahhhhhhhhhhhh6742]

That's a good one!👌😂

[@Jebbtube]

So basically, get plenty of sleep so your brain can poop.

[@Potatobrains_]

lol I wonder if any noise is produced by the glymphatic system, *Brainfarts Confirmed?*

[@camgood2437]

Is "glymphatic" a combination of the words "glial" and "lymphatic"? Interesting fact, Einstein had an extremely high number of glial cells in the areas of the brain related to visual processing.

[@LibbyStephenson]

Hiding in the meninges. Classic.

[@Woodledude]

I grew up in the meninges. They made me the man I am today.

[@jackos5d851]

i hate when something hides in my meninges

[@TheCrash480]

Evidently the best hide a seek strategy, after they finished counting it still took scientists 30 years to find something hiding there.

[@sortedsortof3474]

You just can't trust those meninges.

[@thoainguyen179]

The human brain is the most complex thing , according to the human brain

[@kevinmoore2501]

I have brain cancer, and this helps me understand how neurology, and waste management in the central nervous system works. Good vid. Thumbs up.

[@sthngo]

It's 1 am and now in addition to knowing that I'll have a hard time getting up tomorrow I know that crap is piling up in my brain. Well that's just great.

[@barryminor616]

Sleep RECOVERY HEALin technologies are available if you want ?!?

[@Toastmaster_5000]

Considering sleep is one of those biological functions that there has been no clear answer for, I'd say this is a step in the right direction in figuring that out. Obviously, this is nowhere near enough information to fully explain it, but a stepping stone anyway.

[@barryminor616]

WHY WE SLEEP MATTHEW WALKER PhD center for sleep RECOVERY HEALin and Better BEST Life choices

[@kidcannabis7878]

This explains why i have a dirty mind

[@adevoidvessel]

good nickname

[@fartmongerer17]

😂

[@johnnykilroy3737]

Lmao I like that 😂😂😂

[@sajnaumar3223]

Lol😂😂

[@ahhhhhhhhhhhh6742]

👌😂

[@gijoeljamesmaldonado]

Explains my mental illness. I don’t sleep much.

[@Arombli]

I hope you get to sleep more. There is a lot of ways too take care of your self, so do that! take care :)

[@nerdlingeeksly5192]

joel maldonado same

[@fartmongerer17]

Have you been seeing clowns? Hheheheh sewer clowns hehehehehhehe

[@thisisahumanlol8255]

69 Noice

[@PlaylistunesCommunity]

Hey, one thing that would make your videos even better is the use of a de-esser. It's an audio treatment tool that allows to get rid of the very high-pitched "sssss" sound standard recording gear generates. For example, your video's audio is particularly unpleasant at 1:10 due to many "S"s in a row, but so it goes for the rest too. Give it a try on a laptop, it's pretty annoying. Other than that, amazing job guys!

[@grannykiminalaska]

Despite having lymphatic issues, thank you cancer & surgeon, and despite having described serious illnesses related to occational blockages and failure of lymph to drain this is the first time I've heard what the system does. Thank you. And now I feel even more confident in my opinion that doctors are clueless.

[@bacon.cheesecake]

This explains my shitty sense of humour.

[@fartmongerer17]

What a crappy joke I LOVE IT

[@marciabentley9557]

Thank you for posting this video! Even though I'm a social worker, as a neuro-nerd, I'm always excited about new discoveries in brain science.

[@Player_Review]

Best host, with possible exception of Hank.

[@terrytari1891]

But you're cuter!

[@V.Hansen.]

I love this host. Her voice is so clear and pleasant.

[@megara0243]

One year this Tuesday!!!!!’ You guys rock.

[@ext1013]

OMG...this is probably why, when I seriously pay attention to dry brushing for lymphatic massage (because of recent surgery), I began dreaming again (I also practiced lucid dreaming). It's amazing. I like dreaming. Thank you. BTW, i like your shirt, my way to FL this december holiday.

[@hoebywan]

I'm a night worker and often suffer with sleep deprivation.......and I've forgotten my point. :D

[@noahwilliams8996]

D Jay SCIENCE! ^~^

[@rigrentals5297]

Great video. Loved the molecular structure in the video.

[@robertschlesinger1342]

Excellent overview of the many discussed findings. Best regards, Robert Schlesinger

[@austin9845]

I wonder is this glymphatic system is the reason why sleep and cognitive rest are the #1 treatment for concussions/post concussive syndrome. I had the latter for 8 miserable months. I was in grad school and was discouraged from taking time off to rest, even though I had a medical note. Another doctor gave me adderall to help my focus which increases norepi. It wasnt until spring break when I spent 15 hours a day doing guided meditation in bed, 8 hours sleeping for 7 whole days, no adderall. After that I was like 80-90% better in terms of memory.

[@TJ-sc1pm]

Wow this was amazing !!!! Keep up the excellent work!!!! I love finding out about the latest research about my body and this was super interesting!!!

[@kruton93]

If this is true, I feel like this explains so much... Like the question, "Why do we sleep?" People wondered how it actually recharged us, and this is a pretty good answer. It cleans the brain up of all the waste it produced while you were active! Why is this not talked about more in the science world? I bet there's a link to "amount of fluid produced" to "how vivid dreams are."

[@dolores397]

My dreams a clear and intriguing. Like the avatar movie, I have traveled to different planets with my family. ♥️

[@57hound]

Fascinating video, excellent presentation!

[@dexterlacroy4132]

Looks like Dr Morse scored a point after all. Touché, sceptics.

[@jokwonpope1561]

this is something else that's gonna be added to a science test sometime in 2019

[@NayOnFrames]

Wow, this might be one of the greatest or the greater discovery in such a long time. The Brain controls everything or nearly, a healthy brain is a healthy body. If that System is directly related to aging, then knowing how to manage it, would probably make possible to increase our overall capacity of regeneration, and our entire body's "resistance" to aging, and eventually be able to considerably increase our lifetimes, by many times, even. Excite.

[@SethMacMillan]

My understanding of aging, on a cellular level, is largely how certain diseases develop (like cancer). With this discovery, there's virtually no way it isn't connected to the aging process. You're right to be excite. This may innovate the very focus of treatments regarding psychobiological deterioration of the brain. Maybe not necessarily increase our physical lifespan, but this could be the key to long term psychological health. And, maybe the whole concept of heads in a jar, could be a reality in the not-so-far future.

[@Celevie]

- { Nay } - we dont know how body works but say there is no GOD LOL . JUNKPHATIC atheist lol

[@TheDennisgrass]

Discoveries about the brain and discoveries pertaining to the intestinal microbiome/flora are progressing rapidly. Some SciFi novels center around the idea the microbiome controls the brain.

[@borttorbbq2556]

Not really bet it can help the longevity of our mind most parts of our body are pretty independent with ageing.

[@TheDennisgrass]

Linda Butler: You might find this uctv.tv show interesting. "Follow Your Gut: Microbiomes and Aging with Rob Knight - Research on Aging" kzbin.info/www/bejne/aJqueYCvjN-Woq8

[@omarosweekly1982]

Could explain a lot! Like the "mysterious" build up of undesired proteins or why sleep deprevation and stress are killers in some cases.

[@kcb1995]

This was really interesting. Thanks for sharing!!

[@roberthenahan7885]

great explanation, thanks

[@SentencedToBeth]

I love her hair!!!

[@CarBENbased]

Finally, freaking FINALLY a possible explanation to why we need sleep other than "we just do" that makes sense!

[@Obakawaii]

I enjoyed this. Great work!

[@Neontronique]

I love your new haircut. I love, like really love video's on neurology. This was fantastically done.

[@llamafromspace]

Cool topic, very compelling speaker.

[@voiceofaliens]

Nice visuals. It was helpful to see the diagrams. And cool hair, too.

[@starvalkyrie]

Well my brain certainly has no shortage of gutters.

[@grizzc9127]

I always said that human beings are organic robots. We learn new stuff everyday about our wonderful body

[@kenhtinhthuc]

Amazing video! Although important, sleep is only half (or maybe third) of the story. Unlike the circulatory/cardiovascular system that is equipped with a pump (the heart) to make fluid (the blood) flow, the lymphatic system has no pump. You may wonder what makes the lymph/lymphatic fluid flow through the lymphatic vessels. Well, that's exercise that makes muscles contract and pushes lymph through the lymph vessels.

[@mallardhead]

Important! Thank you!

[@theholisticdog3381]

So amezingly intresting!!

[@ViniSocramSaint]

Great! two more systems to memorize for anatomy and phisiology tests... couldn't scientists and people with brain diseases wait just some more years to get a breakthrough in knowledge and potential treatments?

[@ThrottleKitty]

To the Daleks, the words for "Sewer" and "Graveyard" are the same.

[@TeeJaySmyser]

Love the new haircut! Looks great!

[@Luscid]

Now we know where IT lurks.

[@pv3764]

Ur mother look at me how mature It seems I am ironically doing this and my self awareness is unsettling but it isn't because we are all human and I am not smart though sometimes I think I am but I am being sarcastic but I doubt I am using the correct terminology from my feelings but you might think I am insane but I dont think so but I think a am and this contradiction seems quite obvious and because I am analyzing myself this comment is too long and this may look like an argument to those who just scrolled in but as they read they realize I am completely insane but I am actually not but actually bored and I am just speed typing what I thinking and this would be a good anime moment but I don't like anime so I wont go into that deeper anyways this would be a paragraph but it will it will only be half of a run-on sentence,

[@klattalexis]

This very interesting & smacks of intelligent design.

[@poopandfartjokes]

So brain farts are real?

[@fartmongerer17]

🤣💩

[@johnnykilroy3737]

Bruh 😂😂😂

[@LulitaInPita]

Stop. Just stop. 😂

[@IamTheHolypumpkin]

Good pun at the end hahaha. Good and intressting video overall

[@spencerhale2756]

Can you just have like a gigantic show just with you...you are freaking raddddddddddddd!

[@maxblast8210]

Pretty sure my glymphatic system is just dumping everything into my prefrontal cortex. Certainly feels like it.

[@Selakss]

Asymmetrical bob looking good!!

[@eyeyosef]

Yay. More scientific questions! So much excitement! I can't wait to have a 10-year increase on research time.....

[@ich8159]

I am wondering whether this process being impaired might have the potential to cause issues like intracranial hypotension.

[@alwaysglackin565]

I'm dead that joke at the end

[@AngryKittens]

Maybe it's also the reason why we dream. Just the maid cleaning out the rooms of the brain.

[@carbonman8178]

I think this video is more suited for the main SciShow channel.

[@ricisebastiano]

This was amazing

[@abril561]

Love your new haircut!

[@Xandrabrella]

No wonder my brain feels foggy when I wake up at 2am.

[@mikepierson7447]

Love the Florida shirt great video as well

[@myperspective5091]

This seems like it could explain temporary memory lost after being put to sleep.

[@LulitaInPita]

Omg that makes so much sense as to why sleep is so important to manage chronic pain! (and your well being in general)

[@Nomaken2]

I am constantly sleep deprived. Filthy mind status: secure.

[@mikekuppen6256]

I learned A Thing! Or several, actually. Great video.

[@lyngirasol5773]

Someone I can understand and keep my attention....thank you

[@lyngirasol5773]

You guys should really playback your own videos and when picking speakers, have someone that sounds clear and not dull....all the other woman make me turn with their dullness in the voice...big thumbs up this time

[@sonalirai5835]

Really love the new haircut!

[@dragonthefirelord]

So, the term "brain fart" is somewhat of a simplified scientific term.

[@cuddlewuffle]

woohoo! Rochester! represent!

[@sandragarner6432]

Love the shirt and the new haircut

[@finalbossd]

People always tell me that I have a filthy mind. This must be why!

[@TinchoX]

Holy crap! That's something.

[@xMDawg19x]

Ahh so that's where my dirty thoughts come from!

[@lunathemadman]

Another valid reason for me to nap during the day. Btw, nice haircut!

[@jaysimon2180]

I like her! She is witty and entertaining. Can we add her to more videos please???

[@Captainrizzlicious]

I love your shirt!!

[@jeetjoshi6669]

lymphatics in brain!!! who would've thought

[@sortedsortof3474]

This helps to explain why I am such a mess.

[@fromscratchauntybindy9743]

Awesome info, great presentation.... Brit, time to ask Hank for a pay rise! 😈

[@edwardmontoya50]

Nice support of students

[@nehatheturtle543]

my entire brain is a sewage system

[@TheXextreem]

And so history have been made. This day.

[@chrisholdread174]

Dementia kinda runs in my family. It killed my Grandmother and her mother. Her father choose to eat a bullet at 88 rather then let it take him. I cant say I blame him. I saw my Grandmother one last time a few months before she died, Lights were on but no one was home. For intents and purposes she died long before her body did. Science may keep me from suffering the same fate. At least I hope

[@antimatterbeam]

Awesome hair cut

[@adevoidvessel]

Interesting!

[@ScienceByMike]

If there's no vessels or any structure then where does it all drain too? or what picks up the waster and moves it along?

[@vrstovsek]

Nice haircut!

[@sol_mental]

ScyShow, why so perfect?

[@Charles-ig6fr]

Lymph: "You have such a dirty mind." Glymph: "Yeah, I know. I haven't been sleeping very well lately." Seriously, though, this is a fascinating discovery. Makes you idly wonder if there's any relationship of this physical waste disposal process and REM sleep/dreaming, which I've long thought of as a form mental housecleaning, or if its just coincidental that they both happen during consciousness downtime.

[@dolores397]

All my best dear.

[@thstroyur]

Pretty sure in a previous SS vid - why do we sleep or something - mention was made of a 2013 paper showing CSF 'pumping' in mice that were asleep; lost opportunity for a tie in?

[@panther15zodiacgods47]

Is that the source of nightmares? Brain-cleaning? Nightmares occur in the day as well, and could be called Day-mares, for the night-shift people. Do toxins leaving the brain cause these Night/Day-Mares?

[@AifDaimon]

Basically, the glympathic system is on permanent night shift unless people work night shifts and sleep during the day.

[@fabimre]

A dirty mind? I'll have to sleep on it!

[@sephimaru2198]

4:14 badum tss

[@CorbiniteVids]

if norepinephrine inhibits the glymphatic system I wonder what that means for people whose brains process norepinephrine differently, like myself and others with ADHD

[@OfficialPrettyLittleLiars]

I see that asymmetrical bob! Love it!

[@whatelseison8970]

I don't. It looks like her hair dresser quit half way. Maybe she couldn't afford a full hair cut. Sad really.

[@alanlee1355]

Bob means boobs. 😋

[@lancepate]

only in Indian

[@Brandyalla]

I don't like it either. It looks sloppy and frankly half-assed

[@MickeyD2012]

So that's what's wrong with my dad. He literally has a mind full of garbage.

[@0mn1vore]

Huh. Reminds me of the `open' circulatory system insects have; no vessels, the blood just kind of soaks through to where it's needed. Great hiarcut, btw. :-)

[@cerebrumexcrement]

The sewer system in my brain is broke.