Synthesis of aspirin

[@eleftheriospitsilis2988]

Hey I start working in pharmacutical company in my country your videos help me a lot thank you very much

[@RoxiHulet]

Congratulations!! 🎊🎈🎉

[@alaaali6883]

That scratch sound is so lovely 😂 lol

[@plantinpot5712]

Thanks ❤

[@rey-jc7yk]

I enjoyed this thank you for the awesome content!

[@RoxiHulet]

Glad you enjoyed it!

[@Harsh-vx6pg]

Indian student here ... enjoyed ... greatly done

[@Anne-lg7wh]

Hello! Can you upload the result of the FITR analysis? It would be a great help. Thank you.

[@HasanAl-Mosuli]

Hello, I just have a small question, what are the molar concentrations for Acetic Anhydride and Sulfuric Acid?

[@RoxiHulet]

@@HasanAl-Mosuli the acetic anhydride is reagent grade, which is probably around 99%. The sulfuric acid is concentrated, which is 18 M.

[@HasanAl-Mosuli]

@@RoxiHulet Thank you!

[@user-ew7ih2of8o]

Organic Chemistry 2B. Sierra College Rocklin California

[@sydneyhunt6681]

Do you have to use the Acid Catalyst if given more time? Have subbed good information

[@anakin1028]

Professor Smith, thank you! Can we skip the water bath and put it directly on the hot plate?

[@RoxiHulet]

It depends on how much water or aqueous solvent you have in the flask. If there is only a small amount of aqueous substance in the flask, putting it directly on the hot plate may cause the reactants to heat up too fast and decompose. This is why a water bath is used for this particular synthesis. If there is a lot of aqueous solvent, the high heat capacity of water makes it safe to put the flask directly on the hot plate without worrying about decomposition of your reactants.

[@anakin1028]

@@RoxiHulet I see! You explained it so well. Thank you so much, have a nice day! 💖

[@rohitjoshi4559]

Industrial scale, may I know the temperature at which the reaction is carried out?? Please reply ASAP

[@Brumbrumauto]

why doesnt aspirin dissolve completey in water like the medicine does? wouldthe acetic anhydride react with the water and form acetic acid?

[@RoxiHulet]

Aspirin isn’t very soluble in water. You can only dissolve about 0.3 g aspirin in 100 mL of water. When you dissolve an aspirin tablet in water, what you observe is mostly just the binder material dissolving, not the actual aspirin molecule. And yes, acetic anhydride will form acetic acid when combined with water. I don’t use water in this reaction.

[@hadjernoui8335]

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[@ringit7815]

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[@holasanja6618]

how did it go??

[@user-sc3zy1sz4e]

what is the importance or the role of magantic stiler and magnetic bar ?

[@user-ok8qo3fu8y]

To rotote a mixture?)

[@hadjernoui8335]

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[@umeshkumarahirwal]

Hii Mam

[@johnfitzgerald2339]

This gave me a headache.

[@skiphoffenflaven8004]

Oh come on now. Seeking attention on YT, always, with cliche Hallmark comments, huh?