Siddharthan Chandran: Can the damaged brain repair itself?

After a traumatic brain injury, it sometimes happens that the brain can repair itself, building new brain cells to replace damaged ones. But the repair doesn't happen quickly enough to allow recovery from degenerative conditions like motor neuron disease (also known as Lou Gehrig's disease or ALS). Siddharthan Chandran walks through some new techniques using special stem cells that could allow the damaged brain to rebuild faster.
TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more.
Find closed captions and translated subtitles in many languages at www.ted.com/translate
Follow TED news on Twitter: / tednews
Like TED on Facebook: / ted
Subscribe to our channel: / tedtalksdirector

[@AutumnApril92]

We need more doctors like this, doctors should be scientists of biology but today they are just salesmen.

[@lowruna]

This is a hugh problem in oncology... I met doctors that had great problems with alternative drug use (I do not mean esoteric pills or something) but drugs (certain antibiotics etc.) that had great epigenetic impact against certain cancer cells rather than systemic chemo with their standard stuff (Doxetaxel, Platins, Paclitaxels) and the crazy thing is that they rarely make a chemosensitivity test before using them. So the first line of chemotherapy is "good luck" shot into the void most of the time. There is a big gap between doctors and scientist and patients most of the time believe doctors have some scientist level knowledge which they dont (most of the time)

[@divinecommerce6760]

I got a nice laugh since I'm both a rocket scientist and a person with brain trauma. On most days I cry but got some humor this morning... I write quantum theorems on reverse gravitation yet since my car accident I sometimes have no idea where I'm at when I get out of the grocery store. It's interesting. But I have faith in my brain's ability to come back better than ever with my daily meditation practice, delicious organic nutrition, and my amazing therapists at Boulder Brain Recovery. 😎💛

[@MyCrazyProd]

DIVINE COMMERCE How are you going now ??

[@SparkingLife111]

I'm recovering from brain trauma too. I'm determined to make a full recovery. Also add accupuncture if u can im finding it helps a lot

[@lassusprophetam8209]

DIVINE COMMERCE I hope you also do stem cell therapy come on now if your rocket scientist you should be able to figure that out.

[@fumarate1]

i was an former ice,meth user did i for 10 years by the time i got of it my mind was fucked and fried in the end i turned to meditation and tremor therapy its taken me years to get better.

[@COGGYCOGSY]

Check out lions mane mushrooms,

[@commonman711]

I'm going to tell you right now; the brain most definitely repairs itself. It used to be hard for me to put cohesive sentences together and now, at forty four, I'm able to learn and remember better than ever before.

[@busrakorkmaz7842]

How is brain repapir itself?.. I was fall i a baby... Has something happened?.. I don't know?..

[@commonman711]

@@busrakorkmaz7842 God bless you.

[@beverlyoliverrockspanninga8234]

Fantastic talk! As a stroke patient, I must tell you that I have hope for future benefit of such studies :) Thank you

[@Ugandangirl]

How are you doing now? My good friend suffered a stroke too...

[@parthianwarrior1901]

@@Ugandangirl hey

[@Adam123620]

This is literally how you can get people and especially young people into science

[@arvinsubramaniam922]

Nope. Big words plus chasing prestige does not encourage good scientists

[@wanderingwithkedar]

It's not about Young... This is about Indians (Hindus) gets chance now...

[@Alive6371]

Young people are already into science

[@freeafrikanow]

I have sustained a TBI and I have, fortunately pretty much recovered, my one piece of advice, that I've come across, is to constantly expand your mind with knowledge.

[@yeshuasage3724]

Brad Berry can you elaborate on how you recovered and who assured you that you recovered? I recently got into boxing and fell in love with it, but i leave practice with a headache every time and maybe even a concussion. Any advice would be appreciated

[@yourfirstbukake3971]

Brad Berry what a shame i got an std

[@adamgw9171]

Fantastic level of hope for us brain injury patients & I hope to look forward to brain stem cell treatment to regain the use of my left arm & hand, improve stability & walking & regain what essentially was a 'normal' life. I think this speech gives us all more hope for the future for so many neurological conditions & improve millions of lives very soon.

[@gabrielgomesbrito]

I wonder why these abnormalities such as Parkinson's and Alzheimer's disease seem to present themselves in areas of increased substantia nigra, and what would be the practical results of regenerating lost neurons from these areas using the fruits of this research...nice! Keep it up! Try to gather as much support as possible in order to raise the masses' awareness towards this branch of science.

[@mshmbo]

Thank God, such people to be among us. Thank you prof. and all of your colleagues, you have planted big hopes.

[@thedukeofnewyork4419]

Smart fella with a good heart .. all power to him

[@desikanks]

That was wonderful! Great work Dr. Siddharthan!!

[@unknownpornstar2327]

Love it when u see someone that passionate about what they do

[@ParoArtPixie]

In 2010, I was diagnosed with Ataxia and since then, I've been saying the same thing he is now, but without much scientific knowledge to back up my claims. I am very glad this man can better explain this.

[@Sweetandsour90955]

Did you recover from ataxia?

[@paramjitgill1475]

One of the best talks I have heard and I do congratulate on your articulation on the subject. Your speech points to you being a Malaysian or a Singaporen and Kudos to that

[@angelic8632002]

Fantastic talk!

[@raminaghajanzadeh8998]

We need more innovative people like him, thank you.

[@LeonidasGGG]

My grandmother has alzeimer, and thanks to this man, and other like him, maybe when I'm a grandfather...I won't. :)

[@Angloth]

+Ivo Teixeira Check out this study! stanford.edu/syllabi/smarter.htm It measures activities that help prevent alzheimers quite dramaticly ;)!

[@cameliahudson6438]

??? What do you mean? Just in a few words please

[@mhsg]

@@cameliahudson6438 He means, maybe when he's a grandfather, he won't have Alzeimer.

[@p.bamygdala2139]

Fantastic talk! Thank you!

[@ajouka7238]

True hero!!! You guys are hope for humanity

[@utubedano]

Amazing talk! Awesome!

[@anthonycarney7849]

My name is Anthony carney and I had a mojor stroke 10years ago and I lost my left side I was into my fitness &sport big time for the last 10years I have been just sitting I tried a lot of bevies to try to get back walking again but a sports injury has put me back to the start. I have been flowing brain stem cell treatment on line &it’s looking good 👍 I hope it becomes available in the nhs soon I still have my dreams &I can’t give up this is a fight to the death I am a. Strong man living in a broken body keep doing this great work I am 64years old I believe I can still get a jop &get of the sick 😷 it was great to hear what u where talking about I have put my myself up for a volunteer in this field but no 🍀 Anthony 😊😊

[@philg6757]

I love an optimist,we need more can do`s in this world. We hear to much can`t do,should`t,would`t do and won't do.

[@kakashi76767]

what does that have to do with this talk?

[@lakshitaarora6066]

there are we just need to look for them

[@TheContrariann]

@@kakashi76767 Listen to the last 2 minutes again

[@stemcelltreatment]

Thank you for sharing this video Dr Chandran.

[@TonyTony-jq5fc]

Regeneration Center of Thailand sawadeekhab - please look in to the Coimbra Protocol - 95% of patients remain in permanent remission!

[@acohen3951]

Great video. Definitely food for thought !

[@anjummahmood324]

Thanks for best information

[@kvittoelr]

oh i have so many questions for you, or atleast one that is very interesting. really great talk Dr.Siddharthan!

[@warpussnoluv]

Thankyou sc!great work

[@nathankostelac7352]

I love him so much

[@sa69345]

Wow I just took an exam on this, and my textbook included regeneration of the brain! Amongst other things too.. How interesting

[@rachelanthony6289]

He was just flowing like a stream!

[@mae5419]

Good Talk !

[@tessapjohn]

Worth watching and learning.

[@lloydgush]

Awesome guy!

[@LosAngeles0911]

I really hope the cost will be reasonable...

[@rickmorty5708]

Why isn't this video haven't been talked about in 2021. Honestly this is amazing

[@felixowaga9049]

Very eloquent 👌

[@cameliahudson6438]

Where about can we go for this type of therapy please? And what is the progress these days, after 4 years from your article?

[@HarryBalzak]

Will this work to counteract decades of drug abuse?

[@akhilg90]

Reminds me of Dr Vilayanur Ramachandran, another wonderful neuroscientist.

[@MsGnor]

Electrifying. Thanks for sharing.

[@0xAdam]

Impressive stuff

[@DeepValueOptions]

The reason this happens to peoeple's brain is because the brain isn't used in the right way but instead it's bombarded with stress, anger, and lack of relaxtion.. that's why meditation is so powerful

[@morganthem]

COMPLETELY AGREE

[@dertgild]

Could you provide a source that emotions can do so much damage to the brain? could this sounds like BS

[@DeepValueOptions]

yes, the brain is capable of entering many states of brainwave activity.. ergo alpha, beta, theta ect.. it has been proven that these states of brainwave activity are directly linked to happiness, life longevity, increase in positive outlook on life, and increase in sexual energy.. there are many universities that have published scientific journals citing their findings.. all of which are available to anyone online. Just try meditation for yourself and it will speak for itself

[@SterlingArchimedes]

Not metal contaminates that induce prion formation? Although I agree that meditation and self awareness is mandatory in promoting a healthy brain, there are chemical mechanisms that cause these diseases. Our work environments are loaded with copper, aluminium, and many other metallic residues that can have adverse effects on protein folding processes.

[@gladsheep]

dertgild Why is it so hard to believe that there is a physiological aspect to your emotions that physically affect the integrity of your body and its biochemical equilibrium? A search will reveal that what Psy Qui mentioned is supported by research: news.stanford.edu/pr/96/960814shrnkgbrain.html www.ncbi.nlm.nih.gov/pubmed/9607604

[@Khiarika1]

This is excellent! I didn't unite u def stand the concept of the marrow repairing itself. I wish he'd explained that better, but this would pair up nicely with lissa rankin's principles.

[@AtheistEve]

Are we there yet?

[@satyateja4058]

really a very good news ,seems to be a break through

[@bapubhaskartribhuwan1824]

excellent

[@thatsjustluvly]

Good man Chandran.

[@CriticalDamag3]

very interesting

[@targetsquad3827]

*INCREDIBLE!*

[@franzbuchel7295]

When intelligence, the capacity to see a patient as a whole and unique being, and compassion meet, great discoveries are possible, and a great scientist is born. Which is really rare- but here the case.

[@Angloth]

Amazing

[@berkaygazikara]

one of the things I dont like about TED talks ( as a whole they are great but there a few things that should be improved) is they dont give any references or further reading/watching... if they do, it would be great...

[@eren.c13]

Wassup bro greetings from istanbul!

[@user-kd5ig3vc3s]

Do research on the internet 🛜

[@zak2210]

interesting, i have MS myself and would be interested in reading the full study on what he was talking about....can someone help me find this please

[@MrTomzabomb]

So this was 6 years ago. Where are we now?

[@fortruegood8591]

Stem cells hold the key to the future of medicine. But, as it's shown here with surprised expectations, it should be studied thoroughly and carefully and appropriately.

[@racheldaniels5646]

good

[@joemeschke]

I suffered a brain injury a year ago and am hoping to get intrathecal administration of mesenchymal stem cells to help heal more quickly. It's insane that their use isn't approved in the U.S.

[@nishantkumar05]

Yes

[@JustinKoenigSilica]

nice

[@karanahluwalia]

My kudos to Siddharthan Chandran & TED for this fantastic talk and insights! I pray a cure or path to recovery is possible soon for patients. I speak from a personal loss where my mother had terminal FTD (fronto temporal dementia) and I saw how the degeneation of the brain cells enveloped her into a withdrawed state and it was completely disheartening to see someone so full of life slowly fade away! my prayers and best wishes for more positive cures and potential for people and families coping with the various forms and challenges of Dementia.

[@JackRigbyhimagain]

What a great presenter this man is! BUT who watches TED except for us few diehard believers? He should be on "Dr Oz" and "The Doctors" This process is already out there and proven to a remarkable degree. It only needs SUPPORT.

[@leisastradling628]

Dyscalculia. What can be done to repair?

[@srikanthvhm6362]

Hi sir, very hopful speach, i had a brain stroke last year, and i am suffering left side paralisis, can you please help me out, i want to get back to my normal life, i am from india, i am ready to come where ever you suggest me to come for treatment

[@angelarmicheal2926]

Hello I know someone who can help you with cure and the right treatment. He's a private doctor. Are you interested ?

[@piris91]

i have an scar that cases me to have sizures. Diagnose Epilepsy, It hurts no have sezurs and my arm itches for the inside. So hoping Stemrenu will make me better. Im happy too hear what u have u say about this?

[@ElenCristinaTobias]

Where can I perform a stem cell transplant for Huntington Disease?

[@AtypicalPaul]

Love Ted talks 😀. This one is really interesting. The brain is amazing. Some I've seen make me wonder how they were approved to do one. What are the qualifications for someone to do a TED talk? I don't want to mention any specific talks to put them down publicly. I'm sure many would agree that not all talks are equal in credibility. I am therefore genuinely curious as to their acceptance process and overall intention with the Talks. Thank you

[@sharuchandu9639]

Sir I lost my smell and taste 70% after head injury can I get them. Is there any treatment for the problem Please 🙏 help me

[@morematcha]

Eye Opening

[@ellie698]

God bless this man. Now please.... where are the treatments. PLEASE. 🙏

[@robbieanderson227]

8 years on and don’t see any change

[@ellie698]

@@robbieanderson227 😕

[@robbieanderson227]

@@ellie698 exactly

[@petewalsh4844]

I've always wondered if a lot of brain damage is caused in childhood? The brain is developing and so many kids play sports where it's easier to damage something (brain) that is growing?

[@garyday9457]

What about cleaning out the receptor sites from stuck antipsychotic medication....

[@aisnord1181]

Why he didn't say anything about what kind of natural herbs and foods that can repair the brain?

[@saraigreen5886]

I'm assuming because we are so impatient.... herbs take time. We like quick results. Do you know if any.

[@shailendramorwani9486]

Is there any treatment for cerebral palsy children in this system??

[@Eclipto14]

4:37 - is she sleeping?

[@vanillaskyliner]

Does anyone know what the research paper they wrote was?

[@dawnlapka2433]

Aquired Brain Injury. Healing. I am getting better. Yes, there are effective treatments. And this man and many other Tedx speakers Doctors, Learner leaders can help.

[@helenhart6979]

Yes very much so, I'm living proof of that. Thank you divine.

[@jordangould1541]

I recently suffered a drug overdose and my brain has not been the same since. I have been having trouble remembering things, articulating sentences and feeling more depression and anxiety than usual. I hope that neurogenesis and neuroplasticity will help me to go back to the way I was before.

[@dougmcwilliams7198]

Jordan there are some great videos available on Ted Talks about brain repair. the most important thing you can do is have faith and hope that you will get better. Actually I am certain that you will get better from the research I've come across. Life is a shared experience, but we also largely shape our reality with the power of our mind. Eat healthy food (cut out the meat entirely) some foods are better than others. try to reduce your stress. A little stress is good for growth, but focus on deep breathing and drinking water. Try meditation. Try to exercise daily. Never stop believing and struggling for progress. you will make progress. Life is all about struggle and progress, but progress always wins :)

[@jordangould1541]

Thank you Doug, I can't tell you how nice it feels to have your advice. I'm currently doing everything you mentioned, running, yoga, meditation, I also follow a ketogenic diet and avoiding sugar where possible. I used to be a vegetarian but since the overdose (Jan 1st 2017) I've been eating meat for the nutrients, but I am thinking to be a vegetarian again as I feel happier eating food that hasn't been killed. But I'm worried at the same time that if I quit eating meat I won't get adequate levels of DHA and other important vitamins and minerals for brain repair. I agree with what you say, life is about struggle and progress. I believe we learn the most by facing challenges and overcoming them.

[@naynprajapati881]

I am suffering dippression and my both frontol and left temporal lobes tiny damge how can repair.. Plz help

[@joewilder]

I hope the cost will be reasonable.

[@kantiannambo]

If you ever had damage - well I should say injury you would know if it could repair. The Nueropathic pain I go through on a daily basis sometimes lets me believe YES our Brain can repair itself.

[@rajsrivastav6940]

How r u

[@faisalbi1330]

Hi how are you need help please

[@MindAgilis]

What can we do to improve cognitive performance/ stave off age-related cognitive decline? Could certain video games stimulate and strengthen brain functions such as (working) memory, attention, visuo-spatial acuity, mental flexibility, and even creativity?

[@kakashi76767]

no

[@Arockersfantasy]

+Mind Agilis try reading books

[@vishal9030]

@@MrSean737play sudoku

[@pamelagendron7112]

What about poplar is this curable without medicine?

[@samarc4467]

July 2019..

[@sumikhanseries]

My mom had heart attack 5 days ago and according to doctors her upper brain is damaged, and it's untreatable, so my question is can we hope for good, like can we think that she will come back because she is in ICU , she on life support machines, she was suffering from kindness failure.

[@eduardozepeda3534]

Buena Noticia.

[@Reckyougam]

This sounds kind of like autophagy and the huge boost of stem cells from extended fasting. Since sources also say autophagy clears away dieing cells first also and keeps the healthy ones.

[@joshuahemming1872]

Metal and radiation toxicity is the more plausible cause other then tbi's and lack of physical exercise, as well as moderating the use of technology can prevent this. A solution would be a medication that removes toxins without having a negative reaction on the brains circutry.

[@David-js5yk]

This guy has become super famous as director of many National bodies f Ms and research. He is a smooth talker with great success. But stem cell research for neurological disorders is only used on animals, except in China, where it was tried with fatal outcomes

[@jenamirgholi6004]

perhaps he could be allergic to dust mites. dust mites affect the lungs. They live in carpet and they are microscopic. Just a thought

[@parimalasubramaniam7264]

I dr after vaksin my head elaktri shock i do mri is normal dr never damage what i do never aktive normal dr pls help me dr. My haed very dairy

[@aisnord1181]

Turmeric, ginger, rosemary, garlic, oregano, kale, watercress, water melon, dandelion, swiss chard, spinach, molasses, beans, water, exercise and believe in God's Word.

[@user-kd5ig3vc3s]

Sleep don’t stress and stay away from toxic chemicals and get some sunshine and bathe your feet in salt water

[@TheJrm166]

2:10 "made up of 4 cells" *holds up 5 fingers*

[@wishdokter]

surely one of those is a thumb, no!?

[@PremSuraj]

A person who is very close to me suffers multiple sclerosis, I'm hopeful this research will provide them with a cure..

[@TonyTony-jq5fc]

Prem Suraj check out the Coimbra Protocol!

[@aneliseisfree3602]

Estriol drops has also been used to reverse MS brain legions

[@C_Hart]

At 9 months old I crawled off a 12ft balcony onto rocks below. Severe TBI. Fracturing. Im mostly normal but my memory struggles big time and at age 37 my mental capabilities are seemingly diminishing.

[@davidlo168888]

You can be cured by God's mercy nano-medication, i.e. to help endogenous neural stem cells to be triggered for regeneration, i.e. to clear away those inhibitory molecules.

[@Oxcart44]

Would hyperbaric therapy help?

[@roblovegreen]

Gerald Neil The science shows yes.

[@bigpenis8278]

Ive looked into that as well but isnt there lung damage?

[@annvelop]

After a recent shunt replacement surgery my son suffered a massive staph infection of the brain. The outcome is loss of surface sensation on the right side and severe balance problems as well as double vision. he is in physical rehab and making progress slowly. any suggestions ?

[@Growmap]

+Ncyim Coconut oils vary greatly in quality. Try Tropical Traditions Gold Label. An easier way to ensure you have all the minerals needed in proper balance is Max-Well Ionic Sea Minerals. These are two primary ingredients that have removed a ton of mercury damage I had for decades. Caused by dental fillings, only when I went on a fully organic, non-gmo, grass-fed diet and well water (no city water with fluoride or chlorine) did the symptoms I've had since childhood start going away.

[@yousufdhamangaunwala6744]

I was operated for brain hammorage 4years ago and immidiately after the operation i was parelysed in my right side..so do u think that with stem cell treatment i could be cured

[@DeusHex]

Yes

[@amitbhatnagar296]

I m a paralysis patient from oct2019 after a brain hemrage left side paralyzied is it curable

[@lilysunshine3447]

Reroute damaged mutation? Reconfigure their use to upgrade their significance ?

[@andreasgeorgiou1901]

Please, if anybody has any info on where I could get stem cell treatment for my father please get in touch with me. We are UK based and are unable to travel with him in his current state

[@angelarmicheal2926]

Hello dear I know someone who can help your dad with the cure. Contact him on WhatsApp[phone]

[@UmaDevi-og8hk]

@@angelarmicheal2926 where is this in uk

[@UmaDevi-og8hk]

My son also had a pontine stroke n he is in coma since 10 months is there any treatment we r in Bournmouth uk

[@angelarmicheal2926]

@@UmaDevi-og8hk not in UK. He's from Africa and he has connections allover the world and he can help your dad recover quickly from his illness. Message him for more information. [phone] he's really reliable.

[@angelarmicheal2926]

@@UmaDevi-og8hk hello this that I'm talk about can also help you son with the right treatment.