The DANGERS of SYNTHETIC PERFUME (compared to natural)

[@shoresofreedom]

As a chemist, this drives me NUTS. I wonder how don't people realize that a molecule is the exact SAME no matter if it's extracted from a plant/raw material in a lab or synthesized from scratch in a lab. And YES. Both happen in a proper lab, yet people seem to hate labs. Where do they want their products to be made : a grubby basement or a lab with strict safety rules ? Anyway... I hope people realize that if a molecule is toxic or carcinogenic or whatever, it IS regardless if it's natural or synthetic.

[@senescence57]

As a pharmacologist, big agree!!! The one thing I'd caveat though, is that there are occasional considerations for byproducts depending on derivation as well as the radioactivity variations of the atoms contained therein. Not that radiocarbon is an epidemic, but it can be used as a marker to determine petrochemical origin vs "natural" product isolate.

[@shoresofreedom]

@@senescence57 the only thing a synthetic fragrant compound (singular) can have is an undetectable trace of the solvent(s) that was used for the synthesis, but not all solvents are dangerous, and even if they are, it's not in such a trace amount. a raw material on the other hand, regardless if it's organic or not, always has for sure traces of pesticides and pollutants (if it's something grown on soil for example) that the supplier doesn't tell you about. And when you do quality control on it, it's just to ensure that these undesired compounds are under a set limit (but they re ALWAYS there). Synthesis is practical for scents that are hard or expensive to source, or things like vanillin for instance (because vanilla owes its scent mainly to vanillin) or other scents that are easy to replicate by combining the few molecules that make up their scent. But when the scent is too complex or too expensive to recreate, the natural extract is better.

[@revenge0lobster]

“Grubby basement” 😂

[@DiamondsRexpensive]

Are you one of those people who claims that lab diamonds are real diamonds too?

[@shoresofreedom]

@@DiamondsRexpensive if you don't know that lab-made diamonds are exactly the same as mined diamonds, then you have no idea what a diamond is scientifically-speaking. if you insist on buying or owning a natural diamond, there is nothing wrong with that, but don't go around spreading misinformation.

[@kulineranhore]

All I know is, artificial fragrance irritates my airway, I could have very bad inflammation and get ill for days. It's usually the one in the room fragrance spray or diffuser. In the other products it just gives me a little headache.

[@calyx93]

but do you know what "artificial fragrace" does this to you - just anything labeled "artificial?" I bet you're one of the folks "allergic" to MSG, but eat all forms of it in the multitude of plants it naturally occurs in.

[@ChristopherLeeFragrances]

Drink water stop eating unhealthy

[@kimberlypotts8922]

I have auto immune disease, multiple sclerosis. I wore very strong colognes in the 80s and 90s. I am now so sensitive to any type of cologne or perfume. I cannot convince my family to respect when they visit my home. The last visit, my son-in-law, after being kindly asked to please respect that I get very ill from his cologne, wears it anyway. The left side of my face drooped for a week and I had intense migraines, nausea. He never apologizes, even though he is a very kind decent human. He just says oh I forget. People that wear strong colognes do not realize it’s just as offensive as driving up With offensive and loud music. Why should we be subjected to listen to it? Same applies to cologne. Why should others be exposed to it up to 40, 50 feet away even? I feel a hypocrite sometimes. My grandmother had the same sensitivity and I wore my colognes and hairspray anyway. I am now getting payback for that!

[@aena5995]

Soap has fragrance too detergent literally everything

[@XerjoffGuyReplacement]

Damn that sucks im sorry to hear that Kimberly

[@abuzubayr1584]

😂 the ones worried act like they only use vinegar and baking soda to clean their homes and clothes

[@JayMannStuff]

Oh noes! Not chemicals! They contain dangerous levels of molecules! 😂

[@toebeansmeow]

"Chemicals scary!! Nature good!" -misinformed people. Yet, when they learn EVERYTHING is composed of chemicals... they're still in denial lol 🤦‍♀️

[@julietaguilar3924]

It doesn’t change the fact that many synthetic chemicals are known to bioaccumulate in the body and in the environment in which has toxic repercussions

[@Billtrueman]

that seems to be the exact opposite of what Sam is saying here and in all the evidence provided. You statement seems too generalised and not evidenced anywhere with research is the message.@@julietaguilar3924

[@jarno_art]

Fragrances have become a HUGE hobby that makes me soo happy in this past year.. but now i found out that it's maybe very bad for my health i'm soo sad.. i hope your video will change this and give me some answers on what to do now :(

[@Jenn_N]

Thanks Sam! This was really informative. It is true anything can be toxic it all depends on the amount of exposure. I wonder how they put controls on the testing of things when people are exposed to so many pollutants daily in all of life. Ultimately it's up to individuals to decide what they want to expose themselves to when given the choice. You did a good job pointing out misinformation that is out there and suggesting looking further into the motives behind what people are saying. Great video!

[@triciaroy]

I’ve always loved fragrances, but I’ve also always had migraines. After going to a neurologist, I learned that migraines are not all caused by the same things. Scientists still don’t really know what causes them, but many believe there is a connection between gut micro biome and the brain. Any stress to the gut or the senses can trigger a migraineur’s brain. For years I thought that it was the alcohol or the additives in perfumes that “caused” my migraines (just like drinking alcohol seemed to as well), but the predisposition was really in my gut. Once I took a medication that treated gut bacteria, migraines lessened dramatically and eventually stopped. I can enjoy perfume again, and I’m loving it. I think a lot of the perfume/synthetics aversion among migraineurs has to do with the strength of the scent. If a scent is strong or sharp, it overwhelms the brain’s ability to handle it. I will probably always be sensitive to scent. I still can get mild headaches if a scent is too strong for me, but it’s nothing like what it was. So, the takeaway here is that if you have chronic migraine, the perfume might just be a trigger, not a cause.

[@aaron4387]

My dog came into contact with my neck after I sprayed fragrance on some years ago. next morning when I got home he was completely covered in hives. Be careful with your pets and fragrances/ chemicals.

[@SouluxeScents]

I have a question reguarding all the chemicals used in perfume making. If we are a beginner just starting out with a few natural but mainly synthetics and we are diluting + blending to play around with different notes and accords… are there any combinations that can be deadly or poisonous? Is there a list anywhere that lists what can and cannot be mixed with eachother and if so how do we know how much to use/not use?

[@Zidbits]

What do people think causes those nice smells in "natural" perfumes? A good portion of the time, it's the same damn chemicals used in the synthetics - just isolated and more pure.

[@Parabellumjohn215]

I do wonder what chemicals are in cheap clones, do they contain more “bad” chemicals?

[@johnnycomelately6341]

Well done Sam, this helps prevent some ignorance in the overly fearful peoples world. In terms of rating danger, marriage is far more dangerous 😉

[@hectorelmexican4014]

😂😂😂

[@danielqualls9321]

Is it any safer to spray the fragrance on clothing rather than your skin? Are these potentially harmful ingredients harmful when absorbed into the skin or inhaled into the lungs?

[@peewee678]

Absorption through the skin is, in general, potentially more harmful than inhalation so if you really want to be on the safe(r) side, spray it on your clothes. In the past century, dozens and dozens of ingredients have been prohibited so chances are that several of the ingredients currently in use could prove to be potentially harmful somewhere in the future. However: the risks for serious side effects are probably really, really small. It's also very important to take into consideration the _amount_ of exposure. Someone who is wearing a spray or two every now and then is simply less likely to suffer any adverse effects than someone who takes a bath three times a day in their favorite perfume.

[@Westhamsterdam]

Check out these "fragrances" on woman´s sanitary products. Many are deemed "skin irritants" but could these fragrances" be responsible for things like cervical cancer?

[@aena5995]

​@@Westhamsterdam😢😢 yes fragrance has endocrine disruptors but everything has fragrance and our society expects us to be dosed in it so what to do

[@mirodonpiro]

To me, the question is rather if a synthetic molecule really smells as organic and dynamic as a natural substance. In my experience, synthetic molecules (almost) always smell the same and are more monotone compared to natural materials. Similar to wine. You want a good wine to have the natural qualities of ripening and getting depth over time, so it contains mistery and magic. Synthetic aromas do not always change as nicely as natural aromas over time.They often are more stiff and have sometimes less depth then their natural counterparts. You can smell synthetic Linalyl acetate and it smells exactly the same from a factory in India as from one in france. This makes perfumery boring. If one would use a natural oil containing natural Linalyl acetate every batch would smell slightly different depending on the earth, weather and harvesting method of the plant it came from. Would you agree with me? Ofcourse the above does not count for synthetics that dont have a natural counterpart like Iso-E super.

[@mirodonpiro]

Its like the difference between a handcrafted custommade boat, made from woods and precieus natural materials, or one made from premade parts produced in a factory and just screwed together and sealed. I think they are both safe to ride the waters, but which one is more unique and has more character of its own?

[@sammacer]

Synthetics aren’t meant as a replacement for naturals in perfumery, indeed naturals are often used to add depth and complexity like you point out. Naturals and synthetics used together make the best perfumes in my opinion.

[@torbenchristensen1481]

The world needed this video. It will save me 26 minutes of aggrevated speech everytime some woke person provokes me :-)

[@DiamondsRexpensive]

Maybe just don't talk with stupid?

[@sammacer]

Haha thank you!

[@justaddlight]

This was great Sam! With so much information readily available now to the average consumer, there really is no need to overtly trust any one source, authority or regulatory body. I think it's important for every individual to do their own homework on the issue and consider the data for themselves without ever holding to a final conclusion. There is ALWAYS more information out there, regardless of the derisive attitudes that seem to prevail in uncomfortable matters, especially if they concern a personal passion or fundamental belief. It's so much easier to either accept or dismiss an issue than to intimately examine its foundation rationally and with penetrating discernment. Certainly one of the factors that has led to the prevalence of ignorance and taboo. There's also something to be said about listening to your own body. I know of a few people who completely abandoned perfumes that use high concentrations of synthetics for natural materials and reported a significantly higher tolerance as well as a decline in headaches and associated symptoms. Personally, I've become increasingly sensitive to woody amber materials myself, so I both limit my exposure to perfumes that I already have that contain them, and avoid purchasing new ones that do (a feat in and of itself!!). I'm confident that once our civilization abandons our current problematic and frankly antiquated models of physics for a completely new understanding of existence, we'll likely realize that everything humans have manufactured in the current age has been harmful to us in some way. Until then, safety is really just a game of probabilities. Taking responsibility for our own actions and decisions is a good start.

[@Westhamsterdam]

Hmmmm, "trust scientists" Normally scientists follow the money & who is paying for the studies in the first place

[@Titemaud]

This is a very good and important video. In my last job customers always pointed that there would "surely be chemicals in our products due to their bright colours or strong smells". I never thought to go as simple as water or sugar, but I told them "Yes, mayonnaise is a chemical reaction, and cyanide is natural, I'll take mayo over it anyday. Also did you know chocolate is deadly to dogs, and oranges to rats ? But not for humans... Now, what we are talking about here are SYNTHETICS ingredients, as in made in a lab instead of found in nature. blablabla" 😄 People are distrustful of what they don't know, as they should. I believe it is our job as cosmetic/perfume professionals to educate them or at least help them understand what they put on their skin. You want all natural ? Sure, just know it'll be more expensive and probably less diverse, and in some cases maybe harmful for the environment. And synthetics can be a good thing. Stability of a molecule, cheaper prices, sustainable, ... I also think of blood diamonds for example. My engagement ring is a lab made moissanite. I couldn't be happier with it and it cost 10 times less than a natural diamond.

[@PappyMcPoyle-vj4vt]

Remember that skit where Penn and Teller had a woman go out to get signatures to ban Dihydrogen Monoxide?....... People are scared of chemical names.

[@Titemaud]

@@PappyMcPoyle-vj4vt Oh yeah, definitely. That’s why I think it’s up to us to help them understand what’s what.

[@funksobravo1]

Anything that is synthetic is not good for you, period!

[@joshl1443]

I get painful hives on my throat if I breath artificial fragrances (deodorant, laundry detergent, plug-ins, candles, etc.) I've never had this reaction to any other scent from "nature" ie, rosemary, lemons, lavender, etc.

[@blakewalker8770]

Sam, I enjoyed your video. A great breakdown- a well balanced view. I do not enjoy the fact that so many products are scented that they clash in peoples homes and often bond to food. Some US grocery stores sell food that taste like laundry chemicals, bombarded by floating compounds that latch on to everything. Lastly, you have gorgeous hair! Please keep making videos. Thank you again!

[@sammacer]

Thank you! And I’ve been seeing more unscented products recently so I guess many people share that opinion

[@imaprettygnome9287]

I got your fragrances in the mail today! I ordered the collection when you opened up shipping to the US. They are all beautiful and I am looking forward to seeing what else you are able to create!

[@BatmanBateman.]

I stopped using fragrances entirely because i wanna avoid reduced sperm count. So, you're saying there are no risks at all of using fragrance daily?

[@Silverfox.J]

I have a similar reaction to synthetic perfumes as I do to the uncanny valley it makes me queasy and repels me. I don't know if that's anyone else's experience

[@1just2confused3]

"It may cause reproduction harm and more research is needed" Sounds safe to me, I'll be your lab rat any time you want! The modern world is full of hundreds of new compounds that our ancestors and our livers did not evolve to metabolize. The prudent and wise person attempts to limit the number of hyper novel synthetic molecules, not increase that number. Your business relies on the conclusion that synthetics are mostly fine, so your financial motives prevent you from being unbiased. That's obvious of course but worth stating somewhere. And then another obvious thing is that you use pejoratives and other slights to ridicule anyone who is not willing to be the test subjects for these shady hyper novel compounds that lack true longitudinal studies. There are many of us that dont want to roll the dice. We know the FDA and other regulatory agencies regulary allow known carcinogens to be used in food and beauty products. We know regulatory capture and corruption are widespread and many studies are influenced by those who financed the study. Avoid all of this mystery and stick with natural perfumes and oils. It's easy. Perfume has been made this way forever. I know folks will disagree with me, call me some mean names and insinuate I am a savage anti science, hippie anti intellectual who just needs to get hip with the times. I am unaffected by such provocation. My perspective is the prudent one. So it is. 😊

[@DiamondsRexpensive]

No, you're right. We're the experiment rats. In the future, I'm sure they'll talk about the hazards just like they do when talking about past hazards.

[@davinarasmussen]

Your opinion is prudent, and your argument quite well formed with many valid points. I am a (mediocre) herbalist, extensively study essential oils, and I also make perfume. Based on those things I believe it's important to recognize that natural things (like all things,) have great potential to be dangerous or detrimental to our homeostasis. People putting lemon oil in their water to lose weight, often end up with ulcers of the digestive system... But it's been pushed by MLMs to be "safe and natural." A pack of wolves is "natural," but still have the capability to be quite dangerous.

[@Alireza-bw6jg]

Thanks for the review! May I ask what is your opinion about cloning companies e.g. in UAE? Do they follow any health regulations, or do you know any of them which they do? Also some of these middle eastern clone perfume are made in France, are they better in quality and regarding health concerns compared to the ones that are produced in UAE? I would appreciate if you respond as there is no information about that on web! Thank you in advance!

[@whaleshrimp111]

Recently my girlfriend started wearing perfume that effects me by making it hard for me to breath. She refuses to discus the subject stating that isn't wearing perfume. Maybe it is something in the soap she uses when washing her clothes?

[@kerrygearin3910]

Even dryer sheets could cause this

[@toomanymarys7355]

Or shampoo. Smell all her products lol

[@FrancisFjordCupola]

Good job fighting misinformation. Sadly though, being informed requires careful thought and stupidity can cruise on and on, full speed ahead.

[@sammacer]

Thank you, much appreciated

[@chazpezz]

Excellent and informative video. Thank you Sam. It is a shame that there is so much conflicting information surrounding this topic on the internet and anecdotaly from people who sensationlise everything. The human body is incredibly resilient and fragrances are just one thing that can contain potentially harmful contents. The food we eat and the environment we live in have as much play, if not a lot more than something like perfume.

[@lnz3704]

You know what, allergen is very ambiguous term. It depends on personal human immunity. And there is no standard to it. Dust is an allergen for people who cant deal with it. And based on statistic, dust allergy case is alot. But thats because human immunity is degrading. Dust is not the culprit

[@EdwardJosephShields-ux2vu]

PS: Also, water contains dangerous levels of Hydrogen! 🙀😹

[@ashleylala4293]

Years ago I was suffering from the most horrendous migraines you could imagine with increasing frequency. Luckily I found a really intelligent Dr who knew to test me for chemical toxins. Lab tests showed sky high levels of two neurotoxic chemicals (bromopropane and perchlorate). She had me do glutathione IVs to bind and remove the toxins from my system and the migraines improved tremendously. This was the beginning of my awakening about the health impacts we are all suffering from unprecedented levels of chemicals we are being exposed to in our air, food and water. I am much more cautious now and try to minimize my exposures as much as possible. I love perfume but I do notice that many fragrances can trigger my migraines. I try to only do one or two sprays and generally on my clothing instead of directly on my skin.

[@athenalong]

Why were they so high? What were you ingesting/coming into contact with?

[@lakkarajushankar]

Good video. You need appeciation. People should know the chemical, either natural or synthtic will have equal good or bad effect.

[@sammacer]

Thank you

[@amandaadeyemi5592]

Thank u so much for making so much content!

[@Perfumery_by_Sabin]

Synthetics are the devil! 👿

[@AllthewayupG]

Thanks i just rub some natural plants on my clothes after this

[@VeganChiefWarrior]

ive been wondering about this alot so thankyou for this, i NEVER spray directly on my skin because i understand that whatever sits on your skin goes into your blood stream but i do worry about sniffing it in all day as im constantly testing multiple samples a day and often gass myself out, definitely effecting my air quality lol the fact they block my nose and ive developed alopecia on my beard is a worry, as im healthier than most people but stress could also be the cause i did recently lose a pet

[@JurijPopotnig]

Man if you're a vegan that is 100% the cause of your poor health. Humans are carnivores, we have 4 organs to process animal fats and none for fibres. Plants have no nutrients for humans but a ton of carbs that damage your health. Eat eggs, meat, all animal organs, bone soup, ruminants have the best nutrients for humans and nothing else and you'll be fine.

[@Samuelee97]

They banned lily of the valley 😭😭😭

[@arellycarrilloavila3317]

I really enjoyed your video. I praise you for your common sense opinions (not as easy to find as you may think) and your science based assesmentes

[@lsb8684]

As a scientist I think there’s not enough information, and we should probably avoid using fragrances until further research. People should know the lack of information and then take an informed decision.

[@kita_semula1524]

Hi bro. Do we need to add distilled water for making perfume? I saw a tutorial when he make perfume, using DPG, distilled water and ethanol? Perhaps you can explained? Thanks mate!

[@amazonamazon4872]

You can, but it isnt required. Its a personal preference.

[@sammacer]

Exactly

[@manie3232]

Just be safe and use all natural.

[@GoingOrbit]

Make video about the dangerous of looking good and smelling even better.

[@DiamondsRexpensive]

Lol

[@eicrusade6161]

I believe there are 3000 substances approved for fragrances, but like you I think they only look at individual chemicals and not effects of combining chemicals. You talk about concern for self but what about concern for others. One area requested for study is neurotoxicity of fragrances. Of course, fragrances don't just mean perfume-cleaners to candles to cologne. Plus, tons of sprays. I just know when I gave up fragrance products my fibromyalgia was cured, and my disabling migraines were less, but I had to leave my job because others didn't care. I now wear food grade extracts for perfume my favorite Mades scar Vanilla, but I can stop and actually easily wash if off if makes someone ill.

[@--------RR007----------]

Good job on this video! Great info.

[@rohanbhise514]

My channel

[@PeaceLoveHappy]

I just know that when I’m around people wearing a cloud of perfume I end up with migraines and or runny nose. I know other people that do too. But I can use many essential oils with out getting migraines.

[@islandspicehawaii]

Aloha Sam... if you would like to do a show/podcast on this, feel free to reach out. Have a great day... Spice

[@christieo1761]

Bravo!👏

[@mx9181]

Your Facebook please?

[@sammacer]

@lux.terra.perfume

[@danielszelmenis8392]

For my one of my subjects in school we need to make our business idea, and my idea as a fragrance lover was ofcorse to make a fragrance. since the idea needed to be uniqe and something interesting I decided for a brand that makes top quality like your everyday fragrances. yet they are as nature safe or eco as possible. I have gathered a lot of information. yet I still can't seem to find how to make it as nature friendly as possible. May I get some help. it whould be very appreciated

[@nathanfarkash2689]

Best fragrance channel ever!

[@billfriendtoanimals2953]

The human body has evolved for thousands of years. If smelling a certain way was advantageous, we would smell that way.

[@pulp5618]

how your hair is so perfect?

[@marshalbass7098]

Synthetic hairspray

[@konradzlu5h]

WHat do you think of CAPACE EXCLUSIVE HOMBRE CLASSIC? How much toxic can be this beautiful fragrance? (Amazing fragrance for 5 EUR in ACTION Market)

[@AMGTT]

Well we know u need both synthetics for longevity natruals for realistic scent

[@Emptidiot]

13:35 Did you mean voluntary in The UK, since Brexit?

[@marmtzMX]

" Karen, you are a Chemical..."😒

[@sammacer]

😂

[@michaelmeshulam6983]

Great video Sam!

[@dumbage]

thanks i was just trying to find good natural ones

[@kevencaraballo1990]

I love galaxolide… I might stop using it 😅😂😂

[@afs1476]

before one can quote and legitimize a study or article, you have to "follow the money " and see where these entities get their funding. This is the true conflict of interest . If you believe the IFRA, and they get their money from the fragrance industry, you are a fool to believe anything that comes from them. An example is the pharmaceutical industry that funds research on their own products, funds the scientific community, funds the professional associations and the journals and ultimately funds 44% of the FDA budget. So tell me ,who do all these groups actually work for. Don't be a dupe. Follow the money and see if these sources are truly independent.

[@sammacer]

I don’t believe it’s all some massive conspiracy. While conflicts of interest will occur with some bad actors, I believe the majority of the scientists and employees in these big companies want what’s best. What better alternative is there?

[@DDH64812]

Thank you for the clarification. Most informative!

[@kadebeglen551]

I was just thinking about this subject. This video covered what I saw online and more. You helped solidify my knowledge on safety standards.

[@1015SaturdayNight]

Henry Rose addresses this with their transparent ingredients list and I am interested in trying them

[@JC50-joy]

I am very sensitive to things I breathe in. They can cause me horrrible headaches. But since I make my own perfume with essential oils, I have never had such problems

[@koflan]

When reading an article on the internet, it's important to take a step back and ask yourself: is this article blisteringly stupid?

[@sammacer]

Haha good point - sadly not everyone might realise when it is 😞

[@Reina.Nijinsky]

6:06 here in the US we pronounce that as “tha-layt”

[@danlightened]

Everyone is a bit biased because of their principles and ulterior motives. In case of companies, that would be making a sale. I'm aware of the excess greenwashing many brands are doing. But due to them, some harsh chemicals are being phased out. Gentler surfactants are starting to be used instead of SLS. I'm sceptical of every brand, whether green or not. Because most companies would go to any lengths to increase their profits. These brands are the same people who claimed doctors 'recommend' cigarettes for kids in their ads.

[@toomanymarys7355]

SLS doesn't harm the vast majority of people in any way whatsoever or their hair. So....what?

[@danlightened]

@@toomanymarys7355 It is. It's harsher and strips off all the necessary oils and good bacteria on our skin. The skin of my inner cheeks were peeling and sloughing for years and no dentist gave me any solutions and were usually just dismissive about it. I googled and almost every answer blamed it on the SLS in a toothpaste. I used a SLS free toothpaste and haven't had a problem since.

[@jordillo777]

Brilliant explainer, thank you!

[@jura_rose]

Amazing video. Thank you for taking the time to make this. 🙏🏼

[@gordianusthefinder9862]

As always, a great video Sam. First off, I use both synthetic and naturals in my experiments and agree with everything you say in your video. However, I've thought about this question beyond the impact of the aromachemicals themselves. I wonder about the broader impacts of the syntheses of the various compounds (disposal of waste products etc.) vs environmental impacts of harvesting the raw materials to produce an essential oil or an absolute and which, overall, has the greater detrimental effect on the planet. You also have the choice of getting an aromachemical that's purified from a natural source vs synthetically made. Is one of these better than the other. Finally, since the synthetic processes often produce multiple isomers which can be difficult to seperate from each other, is this a significant problem overall? A number of harmful effects (or degree of pleasant aroma) are isomer specific. Enzymes used by plants to synthesize the various compound in general have a much greater ability to produce single isomers. Appologies if all this is outside the scope of the question. Take care.

[@sammacer]

For sure, the environmental impact will always be a question but there are no generic answers - it must be taken on a case by case basis and most manufacturers probably ever try to quantify it in the first place. Yes nature can often have better mechanisms for producing specific isomers, but it wouldn't be true to generalise that that's a main cause of harmful effects either.

[@kevinverspoor4796]

phthalates haven't been used in most fragrances in the USA as of late. Further studies have been done by the FDA of the USA showed that there were no real issues with Diethyl Phthalate. It's safe for use. Many companies are claiming that their cosmetic and fragrance products are phthalate free. However is there are about 8 phthalates that are not great for people. IFRA banned those quite a few years ago.

[@smfsaqlain]

Great contribution

[@godis.love.]

Please make a video on how to make perfume/ fragrance for foods . THANK YOU

[@sammacer]

I have no experience in that unfortunately

[@godis.love.]

@@sammacer ok thank you but if you get to know please make a video on it thank you

[@athenalong]

What is a perfume for FOOD???

[@Cleanovenco]

Just ordered one of your bottles. Ryan :)

[@sammacer]

Thanks Ryan, I appreciate it 🙏. Let me know how you like it!

[@Spikypotato.]

What a great video!

[@aidenoday423]

Being new to this, where can I get the best quality ingredients? From the US btw

[@sammacer]

Check out my “how to make perfume” guide on the front of my channel page; I give a list of suppliers

[@aidenoday423]

@@sammacer Awesome, thank you! What size ingredients would you recommend starting with? Anywhere between 5-25g?

[@A21Productions]

🙏🏾

[@JayMannStuff]

Also, Salicylic Acid is also known as Aspirin. 20:30

[@senescence57]

Technically I think that's acetylsalicylic acid, but it's chemically close.

[@shoresofreedom]

Salicin (which is found in willow bark extract) and salicylic acid both gave people stomach ache as a side effect when ingested (for their anti-inflammatory effects). Acetylsalicylic acid (aspirin) which is a slightly transformed form of the previous, did not have that side effect which is why it blew up.

[@senescence57]

@@shoresofreedom haha we meet again! Technically, I wouldn't think that's the main reason. Salicylates as a class, including ASA, are ALL linked to GI bleeds as a class. NSAIDs drugs in general have that risk because of the anticoagulation action inherent in the COX pathway attenuation activity that exerts their antiinflammatory effect. That's largely why so many of these drugs come in enteric coatings and have overdose warnings (that and hepatotoxicity). Also, there's prolific forms of deacetylation reactions from the body's metabolic enzymes (as well as regular hydrolysis), so acetylation can be used to alter the pharmacokinetic profile of a (pro)drug while still ultimately ending up as the same base molecule in the body. This is the idea behind N-acetyl cysteine (more bioavailable cysteine) and acetyl carnitine (more bioavailable carnitine). Not entirely sure of the bioavailability profiles of ASA vs og salicylic acid, but there is another effect of the acetylation: increased palatability. Fun fact: there is actually a common drug containing un-acetylated salicylic acid (as a molecular component) that we take to IMPROVE gastric health funnily enough! Any guesses? It's pretty common lol. (Answer: Bismuth Subsalicylate aka PeptoBismol. It is capable of liberating salicylate ions from its complex.)

[@shoresofreedom]

@@senescence57 thank you for the pharmaco deep dive! so i guess that's why they tell you that too much aspirin can make a "hole" in your stomach. i had read that the reason for its success was what I said before, but thank you for explaining that they all have the same side effects.

[@senescence57]

@@shoresofreedom Shore thing haha. This actually just made me realize something. I kinda brushed over the palatability thing. In case I didn't make it clear, I meant ASA is less bitter. I think that might be a general effect of acetylation. If you're deep enough into this channel, you probably know that acetate esters smell sweeter/fruitier than their free alcohol group counterparts. I have a feeling acetylation may do something similar! N-acetyl cysteine smells sweeter and less sulfuric than cysteine and I think similar has been reported for carnitine.

[@ashleykimathi9020]

Sound quality crisp and engaging ❤

[@sammacer]

Thank you

[@sammacer]

Thank you

[@sammacer]

Thank you

[@amazonamazon4872]

Hey sam, So quick question, in your experience bc im trying to combine a couple ac's to come up with a rough idea for an ancient egyptian essence, kinda based off of what 1999 "the mummy" would smell like, im londa stuck on the animalistic leather accord to incorporate, now i ve tried a rough combination of castoreum blend, suederal, and cypriol....but the castoreum seems to throw it off with like that sharp piss like smell...ive ordered a 60% hyraceum (a very underrated and utilized natural imo) bc i have made a tincture of it before and ot seemed to have that more powdery "barn" like smell...is there anything else i may want to try?

[@sammacer]

It’s very open to interpretation! But from what you’re saying, Bran Absolute springs to mind

[@5wm562]

Thank you again Sam for your diligence and dedication to your craft, for personal reasons following an incident involving exactly one of the essential oil materials you mention here that could potentially have been without prompt action fatal (at least to me). Because of _you_ I now know what the material that caused a severe allergic respiratory reaction most likely could have been and can now pass that information onto physicians who _then_ had no clue what was going on. I will add an additional caveat to others, no matter how much we all like things to smell nice that _all_ olfactory materials synthetic or natural should only ever be used for intended purpose per any guidelines given, never added or mixed with other products (soaps,detergents or solvents) or exposed to high temperatures, including hot water.

[@sammacer]

Sorry to hear that happened to you! Hopefully someone can learn from your experience, I think it’s all too common for people to not realise the potential dangers of essential oils

[@5wm562]

@@sammacer In addition to this too many of these companies do NOT provide SDS reports and ignore requests for information regarding 100% "natural" claims. If a company can not prove their product is indeed 100 natural, one may be risking exposure to constituents in that product that can not readily be identified if and when something goes wrong. Thanks again!

[@curlyhairdudeify]

21:16 Wow, she really squeezed lemons with her mouth.... because her friend told her to do it. What a dim twit. Also, citrus essential oil already is a skin irritant in large quantities, and it also is photo-toxic (she went swimming). I thought safety around "chemical" products was common knowledge.

[@olodumareh]

SAM, spell it easy like: fffffff-TAH- lates 👍 Also, lesson i´ve learned from 20+ years ago: NEVER spray perfumes on your skin or hair, ALWAYS on your clothes!!! Great video!!

[@niqerfaguettranykyke]

Depends. I've always sprayed perfumes on my neck as well as on clothes