The Gut-Brain Connection

Duke University researcher Diego Bohorquez and colleagues have identified the neural circuitry that connects the gut with the brain. This pathway is spanned by a single synapse, capable of relaying a signal from gut to brain in 100 milliseconds. This newly discovered pathway is probably exploited by pathogens, and will almost certainly lead to new therapies.
Video produced by The Bohórquez Laboratory in the Duke University Departments of Medicine and Neurobiology. More research details available at www.gutbrains.com
𝐀𝐛𝐨𝐮𝐭 𝐁𝐨𝐡𝐨𝐫𝐪𝐮𝐞𝐳 𝐋𝐚𝐛
The ambition of Bohorquez Lab is to learn how to treat the brain from the gut. Researchers are focused on dissecting the neural circuits that transform signals from food and/or bacteria in the gut into electrical inputs that modulate behaviors like the desire to eat. The laboratory is built on multidisciplinary expertise in viral vector genomics, neurophysiology, behavioral phenotyping, organoid cultures, and neuroimaging. From human miniguts to its own 2Photon -The Wraith- Bohorquez Lab has the pipeline optimized to test ideas from single cells to whole animal behavior.
𝐀𝐛𝐨𝐮𝐭 𝐃𝐮𝐤𝐞 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲
Established in 1924 in Durham, North Carolina, Duke University is one of the world’s leading institutions for education, research, and patient care.
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[@marylamb6063]

I had horrendous depression for 10 years. Zoloft did not work. I traced it to foods I was eating (milk, eggs, sunflower seeds, turkey), which gave me severe depression for three days. Sunflower seeds gave me depression and severe, diffuse back pains. One day I had a nasty sinus infection that felt like heart failure. I couldn't catch my breath and felt tightness in my chest. But I was aware that my sinuses felt slightly sore. It took three different powerful antibiotics to get rid of the infection. Then I dared eat foods that gave me depression. It was gone! Three years later and I haven't had any depression. Unfortunately, the experience was traumatizing and I have some PTSD. Just the thought of that severe depression terrifies me. I don't talk about it to anyone directly.

[@getwellbe]

So important considering that your gut microbiome impacts everything from your immune system to your skin to your brain function to your digestion, and even your mood and mental health!! 👊✨

[@ganeshthapamagar5663]

👍💖

[@DrJanelleSinclair]

The imagery on this video are fantastic! Fascinating video, and it really does show how the brain and gut are interconnected. When people have depression and/or anxiety, they really should look at their gut health. Thanks for sharing!

[@Malitubee]

Dr Janelle Sinclair Right, they did a damn good job on this

[@marianneyag4106]

Wow Dr Sinclair, I wish I knew this, with all the Doctors, nutritionist, dietician's and naturopaths, no one told me this. I wish I knew this 14 years ago till present.. It's amazing, how the food we eat, really impacts our health. Now that I know, changes will be made and everyone else around me, will be informed and educated.

[@PrasanPadale]

How can we keep our gut healthy.? I am suffering from anxiety.

[@maegantucker6684]

PrasanPadale Eat an anti-inflammatory diet. Avoid food sensitivities (can get your gut checked), get lots of vegetable fiber, and eat more fermented foods for probiotics. Also, eat slowly and chew your food until it’s a paste, kind of like baby food. Warm liquids such as lemon ginger water or herbal tea help the gut, too.

[@Shurmash]

@@PrasanPadale bovine colostrum supplement. It heals leaky gut in no time. It also boosts your immune system.

[@fundifferent1]

This makes a lot of sense that the gut and brain are connected. I mean your gut needs to tell your brain if you're full, sick, eating, hungry, etc. It makes sense that sometimes this connection can go haywire sometimes, since it's constantly communicating with the brain.

[@tinacudal5988]

Who ever dislike this video probably doesn't have a healthy gut.

[@iohenderson1880]

Tina Cudal 😂😂

[@zeebotheclown4325]

The bad bacteria gave a thumbs down

[@angryscope]

Zebo the Clown LMAO

[@nutriblooomnutricionistama402]

JAJAJ VERY GOOD ANSWER!

[@sbuceeh]

hahahaha LMAO

[@gayathrich6149]

Simply wow,human body and its functioning is fascinating,it's like a universe ,mysterious

[@intelligentdesign8994]

The most helpful biology information I've come across only in two minutes.

[@brainstormingsharing1309]

Absolutely well done and definitely keep it up!!! 👍👍👍👍👍

[@lunajz-1584]

I always heard that "your gut is your second brain" and now I finally got why x)

[@elainer136]

This video is very short but informative. I have heard of the gut to brain connection in the past but never read up or researched it. However, after watching this video, I am definately going to watch/read more about this subject. Definately recommend this video. Give it a go only 2 minutes of your life.

[@healthybodywithzinzino7630]

What to eat to promote a balanced, healthy gut? Intestinal health is directly linked to the well-being of your whole body. The gut requires a balance of bacteria, which live mostly in the large intestine and part of the small intestine. It’s important to pay attention to our gut health as it goes beyond ‘regularity’ and bloating. The digestive system is the “gateway” to other parts of the body, delivering nutrients to it. A healthy gut contains a dominance of “good” bacteria which produces butyrate, a short-chain fatty acid. These bacteria are dependent on fiber, which act as their fuel. The gut signals to the brain through nerves and hormones, which supports overall emotional and mental health. The millions of neurons in the gut is why it’s often referred to as “the second brain.” What are gut microbiota? Each person has over trillions of microbial cells in the #colon. This makes up an individual’s microbiota. These healthy microbiomes are the key to good health, and, through lifestyle and diet choices, you can promote a good balance. There are factors that throw the microbiota out of balance, such as medications and environmental stressors. For a healthy gut, it’s essential to exercise regularly, reduce stress levels, ensure adequate sleep, and eat foods that are high in fiber. The gut requires us to eat more fibers and less processed and ultra-processed foods that are typically energy-dense, high in salt, sugar, Omega-6 and saturated fatty acids with low nutritional value. Aim to consume a rich variety of fruits and vegetables, beans and whole grains, all of which are high in their own different types of fibers. A key goal to a healthy gut is diversity; eat a variety of different plants and types of fibers. Choose foods that haven’t undergone a great deal of processing so as not to starve the “good” bacteria. However, this fiber intake isn’t always easy to obtain, and the average person does not meet the recommended fiber intake, which is why food supplements are of great importance. Balance your microbiota with LeanShake Just 231 calories per serving, you can source Zinzino’s fiber blend, proteins and over 25 vitamins and minerals easily with LeanShake. LeanShake is a meal replacement that helps with weight loss , muscle gain, and balancing your microbiome, designed to stimulate and boost the “good” bacteria (and outgrow the “bad” ones). The good bacteria contribute in many important bodily functions, such as fermenting dietary fibers, producing vitamins and educating our immune system. A healthy gut is essential for a healthy body. LeanShake is high in fibers with the ZinoBiotic blend, offering more than standard options that typically only contain one or two types, which isn’t enough for our daily intake. LeanShake introduces a resistant starch blend (from corn), oat beta glucans, inulin, fructo-oligosaccharides (FOS) and psyllium husk fibers to the whole colon to promote several bowel functions. LeanShake helps improve the bacterial population in your colon, while reducing a spike in blood sugar after meals and maintaining healthy cholesterol levels. It’s is free from soy, has a low glycemic load and the sweeteners and flavors are from natural sources. With dozens of EFSA-approved health claims, LeanShake is an effective tool for losing and maintaining weight, maintaining muscle, and re-balancing that all-important microbiome, which is a micro-ecosystem that controls so many of the functions in our body. Hence, it’s critical we take good care of it. LeanShake, no yo-yo, diet LeanShake is a delicious, nutritious meal replacement that simultaneously balances your microbiota for a healthy gut. It’s an intelligent mix of vitamins and minerals that help fuel your energy and support many of the necessary functions in your body, from head to toe. And did we tell you the flavors yet? ⭐Chocolate, ⭐Strawberry, ⭐Vanilla and ⭐Berry. Your gut AND taste buds will love it💝 A #healthy #gut = a healthy body Visit to learn more www.zinzino.com/2007533440/GB/en-GB/products/Health/Weight-Control

[@Shurmash]

Colostrum is one of the best things for the gut-brain axis. It heals leaky gut in no time.

[@leelee3386]

Thats in breastmilk right? Or can that be ordered?

[@hopewins1629]

A 1/2 tsp of natural salt will can ease that heavy upper gut feeling that is connected with depression. Mix it in water and chug. The world has trained everyone to be afraid of salt but good natural salt 🧂 has health benefits it you don't overdo it. Anyway, it has helped my gut depression a lot. Also apple sauce with a splash of apple cider vinegar 🍎 🍏.

[@alikarami7753]

great finding

[@petergoettler1385]

Yes,Thxs.

[@peterj.goettler3489]

Interesting To Note! Thxs.

[@muskduh]

thanks for the video

[@sitalakshmi7423]

Amazing findings

[@maheshdebata2991]

Very good, more

[@gopalpathlavath4175]

Thanks for clarifying my doubt mam

[@mehnazsafeer6249]

Marvelous

[@hohnjopkins5705]

You following your gut is what led you here

[@Buckeye_4_Life_]

Eat fermented food for good bacteria...good bacteria is key for a healthy gut biome. Refrigerated sauerkraut, Kimchi(Korean cabbage), plain non-fat Greek yogurt with live and active cultures...stay away from sugary yogurts...and a teaspoon of Apple cider vinegar a day...also eat lots of dark greens to feed the healthy bacteria..including seaweed..

[@gerardog2663]

Is that why I feel so happy when I eat delicious food and my stomach is full?

[@IbelieveinJesusAmen]

My gut tells me....

[@Ace-tc7km]

Could this be possible cause for anxiety?

[@chanelgraham4463]

Adrien Alcantara Yep

[@Vibestr]

Absolutely....you are what you eat.

[@organicfireorganicfire1236]

The cause of gut problem is stones in the liver and gallbladder, so look into andreas Moritz liver flush. ....stones in the liver is what really cause anxiety

[@marianneyag4106]

Yes, wow this has blown my mind. I am a chronic migraine sufferer. I am told to eat carbs, to help the migraine attack, what I was doing was irritating my gut with all the gluten, my body could not digest and it caused more inflammation. I just learnt from this descriptive presentation about the "vagus nerve", I had no idea, there was a gut and brain connection. This explains the mood swings, depression and anxiety. They do say, healthy gut equates to healthy brain and healthy body. I wish I knew this 14 years ago to present.

[@keisi1574]

@@organicfireorganicfire1236 Why have you been eating stones?

[@jameswhelan5271]

The human body is just a crazy mind boggling machine😎

[@satyampandey890]

Woo! It means Brain & Intestine are connected to each other! So is this can be the reason for why I frequently go to latrine during some month before exam

[@totalfreedom45]

We have a second brain in our gut-the enteric nervous system (ENS) with over 100 million brain cells. 💕 ☮ 🌎 🌌

[@itsrockitt]

That was too short. Give us more.

[@HoganR10]

One of those cells is not like the others!

[@hanatesfaye5694]

Wow

[@1drunk_dionysius]

Hipocrates said everything starts in the gut, let the food be thy medecine and the medecine thy food. He knew this long before modern science

[@sureexpansion5318]

I see you shared the embed link. I'll use it for my website. Lmk if thats okay. If not, i recommend not sharing the embed link. Thanks

[@KajanLakhan]

Was around in yesterday's pseudo science - sattvik food concept - but thanks for providing it in today's science.

[@elizalde1014]

I hope someone will spend time to re-discover that the stomach appendix is the real second brain...

[@samsyes5605]

I was facing nervousness problem,and my stomach area was palpitating like heart,so I thought what is the relation between gut and nervous system

[@bmh2570]

I have the same issue, do u still have it if not how did u deal with it?

[@remon563]

that sounds like parasites to me. Sounds scary but everyone has them (its normal).

[@kathaas247]

Not normal to have parasites he’s right though I got rid of mine and no more illness or that heartbeat

[@Wheres-my-toes-bro]

So the saying you are what you eat holds somewhat true.

[@leocampbell5138]

The Voiceover twice suggests the gut is housed in the small intestine. Don't you mean the large intestine, aka colon?

[@hereb4theend]

I just ate rotten meat. I am now one with nature and the timeless force of creation. I am eternal

[@comicartchris5846]

Some people eat that for health. It's called High Meat

[@donnadarcy3978]

So what happens with this communication when pigs and humans have been genetically modified into one being?

[@kevinalix6530]

Can you elaborate on your statement of the Vegas nerve as a pathway to the brain for gut pathogens?

[@yogitopa369]

The Vagues Nerve is connected & runs through the 7 Chakras which is the 7 small glands that attached to 6 organs. Also known as the Endocrine System. Pituitary & Pineal (3rd eye) in the Brain, Thyroid in the Throat Thymus on the Heart, Solar Plexus on Pancreas, the Sacral Chakra connected to the Sexually Organs & the Adrenal Gland attached to the Kidney organs. This is known in ancient culture long ago as the main current from gut to brain. - Cold showers stimulate the Nerve, best in morning, hot showers at night. They are also stimulated through music, food, yoga, meditation It's essential that we sit feet parallel to hips when eliminating waste aka shitting. Digestive system must be completely straight to fully eliminate waste or it will build up over time. 10-20 years can give you lbs/kgs of waste. - Anyways, that's why it's good to have this intelligent connection to live more vibrantly. Singing is also one of the most powerful ways of cleansing, purifying & liberating ourselves from the world things. Hope this helped, bless up

[@yung_seakseak8539]

Cassidy Topa I need some help from you, you seem like you know a lot about this stuff. I drank excessive alcohol for 5 days straight and I haven’t been able to sleep at for months and I can feel this crackling on my head when I move my jaw around. But I feel like it’s all coming from my stomach area. I have high anxiety and stress and really bad digestion. But the thing is whenever I try to sleep I feel this bad feeling in my stomach or my body will jerk as I’m falling asleep? Do you think it’s adrenals or nervous system?

[@BRYANTDOOD]

Getplayed94 Seak im the same where my body will jerk around as im falling asleep have you been able to alleviate yourself of your symptoms yet? If so how? Just wonderin

[@healthybodywithzinzino7630]

What to eat to promote a balanced, healthy gut? Intestinal health is directly linked to the well-being of your whole body. The gut requires a balance of bacteria, which live mostly in the large intestine and part of the small intestine. It’s important to pay attention to our gut health as it goes beyond ‘regularity’ and bloating. The digestive system is the “gateway” to other parts of the body, delivering nutrients to it. A healthy gut contains a dominance of “good” bacteria which produces butyrate, a short-chain fatty acid. These bacteria are dependent on fiber, which act as their fuel. The gut signals to the brain through nerves and hormones, which supports overall emotional and mental health. The millions of neurons in the gut is why it’s often referred to as “the second brain.” What are gut microbiota? Each person has over trillions of microbial cells in the #colon. This makes up an individual’s microbiota. These healthy microbiomes are the key to good health, and, through lifestyle and diet choices, you can promote a good balance. There are factors that throw the microbiota out of balance, such as medications and environmental stressors. For a healthy gut, it’s essential to exercise regularly, reduce stress levels, ensure adequate sleep, and eat foods that are high in fiber. The gut requires us to eat more fibers and less processed and ultra-processed foods that are typically energy-dense, high in salt, sugar, Omega-6 and saturated fatty acids with low nutritional value. Aim to consume a rich variety of fruits and vegetables, beans and whole grains, all of which are high in their own different types of fibers. A key goal to a healthy gut is diversity; eat a variety of different plants and types of fibers. Choose foods that haven’t undergone a great deal of processing so as not to starve the “good” bacteria. However, this fiber intake isn’t always easy to obtain, and the average person does not meet the recommended fiber intake, which is why food supplements are of great importance. Balance your microbiota with LeanShake Just 231 calories per serving, you can source Zinzino’s fiber blend, proteins and over 25 vitamins and minerals easily with LeanShake. LeanShake is a meal replacement that helps with weight loss , muscle gain, and balancing your microbiome, designed to stimulate and boost the “good” bacteria (and outgrow the “bad” ones). The good bacteria contribute in many important bodily functions, such as fermenting dietary fibers, producing vitamins and educating our immune system. A healthy gut is essential for a healthy body. LeanShake is high in fibers with the ZinoBiotic blend, offering more than standard options that typically only contain one or two types, which isn’t enough for our daily intake. LeanShake introduces a resistant starch blend (from corn), oat beta glucans, inulin, fructo-oligosaccharides (FOS) and psyllium husk fibers to the whole colon to promote several bowel functions. LeanShake helps improve the bacterial population in your colon, while reducing a spike in blood sugar after meals and maintaining healthy cholesterol levels. It’s is free from soy, has a low glycemic load and the sweeteners and flavors are from natural sources. With dozens of EFSA-approved health claims, LeanShake is an effective tool for losing and maintaining weight, maintaining muscle, and re-balancing that all-important microbiome, which is a micro-ecosystem that controls so many of the functions in our body. Hence, it’s critical we take good care of it. LeanShake, no yo-yo, diet LeanShake is a delicious, nutritious meal replacement that simultaneously balances your microbiota for a healthy gut. It’s an intelligent mix of vitamins and minerals that help fuel your energy and support many of the necessary functions in your body, from head to toe. And did we tell you the flavors yet? ⭐Chocolate, ⭐Strawberry, ⭐Vanilla and ⭐Berry. Your gut AND taste buds will love it💝 A #healthy #gut = a healthy body Visit to learn more www.zinzino.com/2007533440/GB/en-GB/products/Health/Weight-Control

[@hearts3950]

Nice education about Gut-Brain analysis. As per this video it's a new knowledge. This is western science opinion. It's an old knowledge for ancient Indians more than 2000 year old knowledge in Ayurveda. Refer Sushrutha Samhithe by Sushrutha the first surgeon in the world.

[@MikkoVille]

Yeah, just because there's some gut-brain interaction does not mean that ayurvedic superstition is suddenly correct or relevant.

[@AlexSharayMusic]

American “medicine” is toxic and arrogant. It is good only for trauma cases. The worst thing to do is see an American doctor....he/she will put you on toxic medications that will keep you sick and a slave to SATAN (BIG PHARMA).

[@starlordgg]

There is also a lot of garbage in ayurveda...you can google it. Ayurveda is a hit and a miss.

[@donnelwilson9770]

This is why the word says that the body is the temple of the Holy Spirit

[@ShowCat1]

Why the deep roaring noise during narration? Hard to her what she is saying.

[@Fiverr101]

So if I ate a genius brain....

[@wearelivinginthematrix5367]

Allahu Abkar

[@Darkanight]

1:10 why did u put a fart sound? hahahah

[@Competitive_Antagonist]

I think it's supposed to be electrical noise.

[@johnblake5114]

Welp this is beyond me. What's the solution guys?

[@remon563]

look into Dr. Berg/Bergman. You need to get rid of gut inflammation triggers like yeast/gluten/sugar and eat fermented foods that feed your gut bacteria. Kimchi can be a lifesaver for many.

[@yesididthis1420]

This explain why it's not required to consume meat when you want to engage in meditation.

[@brandon3872]

When did they explain that in the video?

[@gratefulmann6692]

We disconnected a sheep's guts from its head and it died so that's very true, tasty but dead...

[@Bi0Dr01d]

Look how complete the human body is and how sophisticated it is. It is hard to watch this and still conclude we evolved without God creating us.

[@johnblake5114]

Exactly, To think all these things somehow "evolved" at the exact same time (which is essentiall for it to work) is simply crazy (no offence)

[@randomperson-gy5ee]

Exactly what I was thinking. Our body was meant to be the temple of the Holy Spirit. And we are fearfully and wonderfully made. That’s what the Bible says.

[@ryanh5987]

Here come the anti vaxxers