The Horrifying Science of Prions

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Dark Science

Dark Science

Күн бұрын

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@darkscienceyt
@darkscienceyt 9 ай бұрын
Get TypeAI PREMIUM now! Start your FREE trial by clicking the link here: bit.ly/Mar24DarkScience
@SeenDiving
@SeenDiving 9 ай бұрын
it has great reviews, i just d/led it
@PlanetComputer
@PlanetComputer 9 ай бұрын
if this video is about what i think it is (the risk of eating beef and other large prion risk animals) you are based bro
@LOL_MANN
@LOL_MANN 9 ай бұрын
Nah, too much AI G
@existentialcrisisactor
@existentialcrisisactor 9 ай бұрын
Na. AI made you so lazy you didn't even bother to learn what prions are.
@dgmt1
@dgmt1 9 ай бұрын
imagine being so desperate for cash that you'd whore yourself for an app that spews out generic crap with no fact checking.
@GryphonSmith-mk6dv
@GryphonSmith-mk6dv 9 ай бұрын
Prions are such a scary thing, but in reality, any neurological degradation disease is scary.
@mushyroom9569
@mushyroom9569 9 ай бұрын
But most of them aren’t contagious
@zee9709
@zee9709 9 ай бұрын
scary because this thing are so potent similar to rabies
@JokerDoom
@JokerDoom 9 ай бұрын
Sure, but most are age related or genetic. I’m not concerned about getting Alzheimers at 35. This is an actual threat to me, and potentially my whole family.
@Sharp931
@Sharp931 9 ай бұрын
At least it's quite rare in Europe
@rosemiller417
@rosemiller417 9 ай бұрын
Yeah. But one that can spread between Species and is hard to destroy, it's damn scary. And a real Pain for Hospitals operating on affected Patients. When you don't get rid of all Prion on the Instruments, which goes far beyond standard sterilization, you could easily screw next in Line Patient on your Op Table!
@DakotaTuttle-k3x
@DakotaTuttle-k3x 9 ай бұрын
My prions don’t jiggle jiggle, they fold
@timelessdragon8950
@timelessdragon8950 9 ай бұрын
Remix baby!
@just.8797
@just.8797 9 ай бұрын
Ha
@Ssstone3.14
@Ssstone3.14 9 ай бұрын
*dies in agony*
@Sharp931
@Sharp931 9 ай бұрын
Slaps
@Zoeyth3cat
@Zoeyth3cat 9 ай бұрын
Broski why 😂
@19822andy
@19822andy 9 ай бұрын
I remember the whole thing like it was yesterday. Thick smoke filled the air as piles of cows 10s of metres thick burned. Our school replaced their beef items with lamb ones for years. Beef was stigmatised and beef with bones such as the rib eye steak was banned. The scariest thing is there could be a generation of us who will die from vCJD and we don't even know it yet.
@thatsnodildo1974
@thatsnodildo1974 9 ай бұрын
That's scary.
@neptun2810
@neptun2810 9 ай бұрын
I'm not so sure about generations of people getting vCJD in the future. I do understand that this stuff can take decades before it breaks out. But we see a decline in the cases that is related to us figuring out what the cause of vCJD was. A delayed outbreak of the diseas makes perfect sense, but what would make no sense is the outbreak going back, as it did, and then suddenly returning.
@sigiligus
@sigiligus 9 ай бұрын
Hehe, yeah, there’s definitely a generation of people whose genes might be at risk for some crazy shit like this.
@thomasdonovan3580
@thomasdonovan3580 9 ай бұрын
I was working at the largest meat plant in the world Brooks Alberta Canada when Mad Cow broke out, we all lost our jobs within weeks.
@sqlexp
@sqlexp 9 ай бұрын
It won't surprise me if we later find that certain forms of Alzheimer's disease, Parkinson's disease, and many other neurodegenerative diseases can be caused by prions. Eat pork instead of beef just to be safe. Pigs are resistant to prions.
@jokotri2186
@jokotri2186 9 ай бұрын
I've heard cannibalism is a bad thing since I was a kid, today I just found out why. Weird that I never knew the reason behind it except that it was immoral.
@westong9082
@westong9082 9 ай бұрын
well not to defend cannibalism obviously, but it doesn’t cause prions outright, just causes them to spread if they are already in a population.
@c14n_
@c14n_ 9 ай бұрын
It’s just as infectious when eating an infected animal. This cannibalism thing is mostly a meat industry PR thing. Sheep MGM had been thought to have played a part in the cow outbreak
@Ad1nfernum
@Ad1nfernum 9 ай бұрын
​@@c14n_ This is exactly correct. I gotta dig back into my memory banks on it, but I was the court reporter on a class action trial here in Canada related to the outbreak of BSE here, and one of the experts we heard gave extensive evidence about the role that scrapie was believed to have played.
@cxireen2193
@cxireen2193 9 ай бұрын
Same with Incest. Same with Necro/Pedo/Zoo/Filipinofilia
@Failurefaust
@Failurefaust 9 ай бұрын
to be fair, prions aren't the reason why cannibalism is viewed as bad. Many societies look down on it way before we learned prions are a thing
@hasanrize
@hasanrize 9 ай бұрын
The scariest part of prion for me is its stability. Let's say you have virus stock in your hand (in the laboratory) and you want to destroy it, you just need to add SDS, Virkon, alcohol (if the volume is small), etc, and they are inactivated. You can autoclave (1atm 121 degree Celsius) whatever shit is in your hand (viruses, bacteria, fungi, etc.), and they will be dead at the end. But prions are not vulnerable to any of those chemicals or heat that are included in the inactivation. Once you have it, you have to follow strict ways to destroy it, and if you accidentally get it, there is no way to prevent what will happen later to you.
@sigiligus
@sigiligus 9 ай бұрын
Once you have it you are guaranteed to die from it unless something else kills you first. The only conceivable way to treat it would be with nanomachines that could actually find and manually destroy the prions. Although that technology will probably never happen.
@kimlarso
@kimlarso 7 ай бұрын
Read research on viruses eating viruses, bacteria eating bacteria, venom/anti venom 👉just gotta fight fire w fire & find a leads harmful to humans prion
@observingrogue7652
@observingrogue7652 5 ай бұрын
You need steel melting temperatures to destroy prions.
@TheAkashicTraveller
@TheAkashicTraveller 5 ай бұрын
Apparently the protein prion disease affects isn't actualy necessary so researchers are working on ways to remove it ahead of time. The problem then becomes detection, if you're already displaying symptoms significan irrepairable damage has already been done. So it'll probably only help those with genetic prion disease, which is completely unrelated to this outbreak and not result of transmision.
@CinnaMoonGamer
@CinnaMoonGamer 3 ай бұрын
​@@TheAkashicTraveller Researchers have also considered using amyloids to generate sturdy biomaterials such as fibers due to their sheer resilence.
@AmmaSoelberg
@AmmaSoelberg 8 ай бұрын
I remember hearing about the disease as a small child, maybe 4, and then asked how the cows caught it. Learning that enough adults thought feeding dead cows to other living cows was not only ok but a good idea genuinely shifted my perspective on adults. I began to think very critically and be very weary of the decisions of adults, you never know what someone would do if others around them acquiesce.
@johnf.r6658
@johnf.r6658 4 ай бұрын
I'm not trying to be mean but... Did you see how nature works ? All the animals, plants, bugs are constantly fighting and adapting to survive, it's pretty brutal! We are part of that
@ChairmanMeow1
@ChairmanMeow1 9 ай бұрын
Feeding cows to cows seems uh... immoral.
@monkofdarktimes
@monkofdarktimes 9 ай бұрын
Beef Squared
@armanada7600
@armanada7600 9 ай бұрын
and this immoral move came back to bite us, yes?
@Marta1Buck
@Marta1Buck 9 ай бұрын
ba dum tss@@monkofdarktimes
@GrumpyIan
@GrumpyIan 9 ай бұрын
What do you think is done with chickens that passed away?
@mushyroom9569
@mushyroom9569 9 ай бұрын
Why?
@Unchained_Alice
@Unchained_Alice 9 ай бұрын
Who could have imagined feeding cows to cows would be a bad idea...
@Mark_Bates
@Mark_Bates 9 ай бұрын
Precisely. That’s exactly how the disease started. Cannablism is bad no matter what species is doing it
@SOOKIE42069
@SOOKIE42069 9 ай бұрын
it gets so much worse than just this on the typical industrial farm. there's vats of pig shit millions of gallons big that are just sitting out in the sun breeding the most powerful bacteria you've ever encountered, there's chickens packed so tightly together they kill and eat each other to get more room, etc etc. It's possible to buy exclusively meat that hasn't been treated horribly before slaughter but it is pricey as heck and even then sometimes you go look at their supply chain to check their claims and find out one of their farms is dachau or something.
@ericcarabetta1161
@ericcarabetta1161 9 ай бұрын
Don’t they feed fish to fish, too?
@thehybrid210
@thehybrid210 9 ай бұрын
It isn't. The problem isn't feeding cows to cows, but feeding contaminated food to cows
@investidoramador9850
@investidoramador9850 9 ай бұрын
didnt we see that iin the simpsons before
@Edgeworthscravat
@Edgeworthscravat 9 ай бұрын
I was young when the BSE crisis hit the UK. I remember my dad complaining that he couldn't get T bone steak any more, and my mum making us go off beef for a while. I didn't realize how bad the response was from the government at the time...
@naomisherred166
@naomisherred166 9 ай бұрын
I was 20 and was so busy with work etc didn't really follow news. Luckily I couldn't afford beef at the time so feel pretty lucky. Our govt is rubbish at responding to anything lol
@aestheticvibezz142
@aestheticvibezz142 2 ай бұрын
​@@naomisherred166 How can you not afford beef living in UK, sorry for my ignorance.
@ericw3517
@ericw3517 9 ай бұрын
Prions scare the crap out of me. I could have already eaten the fatal hamburger, and I won't know for years.
@thehybrid210
@thehybrid210 9 ай бұрын
If you had eaten, you would've showed neurological disorders within weeks and would've died within a year
@catoverlords9560
@catoverlords9560 9 ай бұрын
Not always true, prions can have a decades long incubation period. ​@@thehybrid210
@SurferBobbyLew
@SurferBobbyLew 9 ай бұрын
Not true your body if healthy and well nourished and functioning well has mechanisms to deal with misfolded proteins. If your concerned FAST and up regulate autophagy. Prion disease occurs when the rate of misfolding generation has outstripped bodies ability to remove and degrade
@salamanderhillbillyweasel1629
@salamanderhillbillyweasel1629 8 ай бұрын
Prions kill you within like 2 years max
@gpt-jcommentbot4759
@gpt-jcommentbot4759 5 ай бұрын
better later than now
@Kopecky_
@Kopecky_ 8 ай бұрын
It feels like the video suddenly stops, like it doesn't have a proper ending
@antoniobranderas
@antoniobranderas 4 ай бұрын
There’s nothing wrong with
@robertromanul2212
@robertromanul2212 3 ай бұрын
- Hello, man-made transgressions against ancient taboos ? - Sorry, protein folding broken - Understandable, we reap what we sow
@notsojharedtroll23
@notsojharedtroll23 3 ай бұрын
Damn.
@norbertnagy5514
@norbertnagy5514 2 ай бұрын
~I think we did it this time There's something in the air inside the star shine There's something in the air we'll never know I can feel it take hold Infected~
@otakuhunter4817
@otakuhunter4817 2 ай бұрын
true
@Marta1Buck
@Marta1Buck 9 ай бұрын
they still ask you if you have ever lived in UK for 6 months or more when you're donating blood.
@sadib4782
@sadib4782 9 ай бұрын
yep, my mom lived there for a while in 92 and still to this day she’s not allowed to donate blood, it’s not allowed in canada.
@tucker3601
@tucker3601 2 ай бұрын
@@sadib4782 Same for my Australian mum. Thinking about it, it's a horrifying thought that you may have eaten a contaminated product and have prions in your body that could trigger a deadly disease even decades after eating it. Must of been a scary thing to live through.
@flipphone4755
@flipphone4755 9 ай бұрын
Prions are fascinating! No cure and nearly impossible to destroy. They’re a perfect monster.
@thehybrid210
@thehybrid210 9 ай бұрын
The only reason it isn't the perfect bioweapon is due to its very limited transmission, not being able to infect a good amount of hosts. So we've got to stick with bacteria and viruses for now
@pants15
@pants15 9 ай бұрын
@@thehybrid210 They've been finding Spike proteins are forming into prions in humans over the last two years now. There's been a few NHS and CDC studies on the matter.
@kimlarso
@kimlarso 7 ай бұрын
@@pants15fighting fire w fire👉experimenting w a less harmful prion to fight a deadly prion👉qualifies as a “gain of function”
@capoman1
@capoman1 5 ай бұрын
​@@pants15Damn, that is scary.... Yet if you were at all curious or hesitant or wanted to discuss the unknowns and lack of research for prescribing an EXPERIMENTAL drug, you were called crazy or a conspiracy theorist.
@amberbush1999
@amberbush1999 9 ай бұрын
Chronic Wasting Disease in deer is another example of this too.
@byronic-heroine
@byronic-heroine 9 ай бұрын
Does that mean deer eat each other? 😳
@Ad1nfernum
@Ad1nfernum 9 ай бұрын
​@@byronic-heroine In the case of deer, they're not entirely sure but sounds like prions are most likely transmissible through bodily fluids and contaminated soil. That said, though, virtually every herbivore is an opportunistic omnivore (deer are known to chew on bones for minerals, for example), so it's not impossible that a deer might eat infected meat directly.
@RynaxAlien
@RynaxAlien 8 ай бұрын
Go vegan
@kimlarso
@kimlarso 7 ай бұрын
@@Ad1nfernumI’ve observed my beloved red Cardinal partaking of road kill👉every animal eats meat/protein
@trevorrogers95
@trevorrogers95 7 ай бұрын
@@RynaxAlienNo I enjoy taking care of my chickens and getting to collect and eat their eggs and won’t let some weirdo on the internet try to rob me of that.
@brianthesnail3815
@brianthesnail3815 9 ай бұрын
In the early 1980s I worked in an animal feed mill in the UK. I worked in the laboratory and we used meat and bone meal to increase protein in the feed. It was cooked to high temperatures. I also came from a farming background and had also dipped sheep with organophosphate sheep dips. It was illegal not to dip sheep and farmers were prosecuted. Some farmers it was theorised did suffer neurological conditions because of exposure to organophosphate sheep dip. Then after the appearance of BSE the organophosphate sheep dips were suddenly withdrawn. There was an article in the Lancet in 1999 about cumulative impact of exposure to organophosphate sheep dips on people. I am unsure whether it has ever been completely proved that sheep neural tissue, brain and other tissue fed to cattle via meat and bone meal could have been the source of BSE. I am also unsure whether potential links to organophosphates in sheep tissue were ever ruled out. I am still unclear if we have ever got to the bottom of why BSE really appeared and why it had not been seen to the extent it was before the 1990s. There is still a lot we don't know and I have never seen any reference to a thorough investigation.
@thorr18BEM
@thorr18BEM 8 ай бұрын
I was once coated in organophosphates.
@awg7068
@awg7068 7 ай бұрын
Scrapies in sheep (spongiform encephalopathy ) was seen in sheep first, as 'downer' sheep were rended and put into the feed of living sheep. This was also done with cow feed, and eventually downer cows were rended for feed as well. Prior to industrialized farming, this practice was not done.
@Ad1nfernum
@Ad1nfernum 9 ай бұрын
I was the court reporter a couple years ago on a Canadian class action lawsuit related to our federal government's handling of BSE. The real tragic thing is it devastated our beef industry, for no reason. The one infected cow being found - which was purchased from the UK - was enough, even though, according to the witnesses I heard from, feeding cows MBM was almost unheard of in this country, out of principle more than anything else. Farmers were simply understandably wary of feeding their cows something so far removed from their natural diet.
@helenpixels
@helenpixels 9 ай бұрын
Who might have thought that forcing herbivores to cannibalize would be a bad idea. Horrible.
@peta8219
@peta8219 9 ай бұрын
Well, herbivores sometimes eat meat, but i get your point
@cAiRo7LoGic
@cAiRo7LoGic 8 ай бұрын
We're Omnivores. That's why we have K9 teeth.
@RynaxAlien
@RynaxAlien 8 ай бұрын
Go vegan
@trevorrogers95
@trevorrogers95 7 ай бұрын
@@RynaxAlienNo
@RynaxAlien
@RynaxAlien 7 ай бұрын
@@trevorrogers95 kzbin.info/www/bejne/bpjUqKOcesh1oKs
@rotoole22
@rotoole22 9 ай бұрын
I actually just wrote a paper for my classes on prion diseases. There are animal ones such as Transmissible Spongiform Encephalopathy
@schizophrenic_rambler
@schizophrenic_rambler 9 ай бұрын
Kuru
@icebiirb9440
@icebiirb9440 9 ай бұрын
tse is just the blanket term for prions? we call human ones that too, such as kuru
@VEV-cu6no
@VEV-cu6no 9 ай бұрын
Can you link
@sigiligus
@sigiligus 9 ай бұрын
Well your paper was shit because you apparently don’t even know that Transmissible Spongiform Encephalopathy is the actual name of the disease and that all the other names such as CJD and FFI are just specifics on how the TSE was acquired.
@rosemiller417
@rosemiller417 9 ай бұрын
I looked Prions up on Google and Wiki.. TSE is the Blanket Term. Scrappy in Sheep, Chronic Wasting Disease in Deer are 2 other I read about.
@zage932
@zage932 9 ай бұрын
MCD is terrifying
@darkscienceyt
@darkscienceyt 9 ай бұрын
Very much
@igoralmeida9136
@igoralmeida9136 9 ай бұрын
just don't be a cannibal and don't eat cannibal animals
@Nohandleentered
@Nohandleentered 9 ай бұрын
McDonald’s is definitely the scariest thing out there
@ricojes
@ricojes 9 ай бұрын
I'm... Lovin' it?
@rosemiller417
@rosemiller417 9 ай бұрын
But how to be sure? Cannibalism isn't the only cause of Prion Infection. Even if it's the safest Way to get it. Interspecies transmission and accidental exposure on the Op Table. Prions are a Pain, standard sterilization Practice are useless. Chronic wasting Disease, Deer, and Scrappy in Sheep are also Prions. It's really on the Farms to safely spot, check and dispose of ill Stock. And to watch the Herd close afterwards as precaution. We only start to understand.
@DustinHaning
@DustinHaning 9 ай бұрын
My next door neighbor died from this a few years ago. Totally insane how that happened.
@sharonrigs7999
@sharonrigs7999 9 ай бұрын
You didn't discuss Kuru...another fatal prion disease caused by cannibalism. That would make a great video.
@Mark_Bates
@Mark_Bates 9 ай бұрын
As I said on a different comment cannablism is bad no matter what species does it
@annak9646
@annak9646 9 ай бұрын
Yes he did - Kuru is prion disease
@sharonrigs7999
@sharonrigs7999 9 ай бұрын
@@annak9646 No shit. I just said that
@sigiligus
@sigiligus 9 ай бұрын
They’re all the same disease you fucking tard. The name is just where it came from.
@cyber_robot889
@cyber_robot889 9 ай бұрын
Its not only beef, but also other animals.
@AlteryxGaming
@AlteryxGaming 9 ай бұрын
Scrapies in sheep, and Chronic Wasting in deer
@schizophrenic_rambler
@schizophrenic_rambler 9 ай бұрын
And kuru
@Tatusiek_1
@Tatusiek_1 9 ай бұрын
@@AlteryxGaminggood thing chronic wasting and scrapies hasn’t affected humans.
@Ad1nfernum
@Ad1nfernum 9 ай бұрын
​@@Tatusiek_1vCJD is literally just other prion diseases manifesting in humans, though. So that's a distinction without a difference.
@chrisdavidson911
@chrisdavidson911 9 ай бұрын
@@Tatusiek_1 testing has shown it to be possible, but it's slow to happen
@SOOKIE42069
@SOOKIE42069 9 ай бұрын
The thing that really terrifies me about prions is how they just hang around in the environment due to their immense stability. Here in Wisconsin the big source of prions is deer. Hunters and the DNR do their best to cull as many sick deer as possible but the reality is some deer are gonna die of the prion infection before they're found and then they're indistinguishable from any other rotting animal that died naturally. Not only will other animals potentially carry away its prions in their guts, but when the animal is fully rotted away the prions are still chilling right there in the soil. prions can be basically anywhere you could reasonably expect an animal capable of generating or carrying them to die. we could end all life on earth tomorrow with our hubris and the only things that would be left are prions and that ancient immortal dog that gets passed around as a sexually transmitted cancer. (ps a video about the immortal dog std tumor would be dope, I'm very fascinated by the question of whether the immortal cells that carry on to this day "count" as the same dog that they originated from. there's fun arguments either direction).
@rosemiller417
@rosemiller417 9 ай бұрын
I mean somewhat, no. It's a Cell Line. How mutated are they from there former initial Host/Body. Is the Cancer DNA still same as from this one Dog? 😆 2. Interesting mutant Cancer tragedy of a Facial Cancer in Tasmanian Devils. Transmitted via biting. It puts real Pressure on the remaining Population.
@kimlarso
@kimlarso 7 ай бұрын
Immortal dog????
@thejacobbook
@thejacobbook 13 күн бұрын
Never eating deer again 😂
@teresamaher1953
@teresamaher1953 9 ай бұрын
There is an amazing book that shows how BSE and TSE, Scrapie and most importantly Kuru developed. Kuru being a form of vCJD that occurred in the New Guinea highlands in the 1950's. I highly recommend it if you want an in depth look at this tragedy. It's called Deadly Feasts, can't find my copy to include the author's name, but it is chilling because Kuru was spread by cannibalism in New Guinea.
@Eosinophyllis
@Eosinophyllis 9 ай бұрын
The family that couldn’t sleep is a good one too!
@rosemiller417
@rosemiller417 9 ай бұрын
Do you mean Fatal familial Insomnia? It's a horrible genetic misfortune. Bad Way to go. Loosing the ability to sleep at all until you die of Sleep Deprivation, for sure.
@john-qm9ni
@john-qm9ni 3 ай бұрын
My pronunciation of "prion" has been wrong since I first learned of them in college. My peasant brain has been saying "Pry-on" as in to "pry" a door. However, the mechanism and science of prions is fascinating, though terrifying. Thank you Dark Science!
@Zim5.0
@Zim5.0 4 ай бұрын
It's scary how these kinds of diseases and infections don't show symptoms until it's too late, it's also scary how they aim straight for the brain
@vyzme
@vyzme 9 ай бұрын
This video jumps all over the place with the naming of the prion disease and simply makes the video confusing and factually incorrect at times. The prion disease that was found in the cows was called bovine spongiform encephalopathy (mad cow disease). The prion disease that humans contracted through contaminated meat consumption in the U.K. is called Variant Creutzfeldt-Jakob disease (vCJD). Most cases of CJD (Creutzfeldt-Jakob disease) are SPORADIC. 2:35 - only 15% of CJD cases are genetic or inherited, while the majority of CJD cases are caused by unknown reasons (sporadic). 4:14 - This is simply false. The prion disease you are talking about is called "Kuru" (transmissible spongiform encephalopathies); it differs from CJD. Kuru is exclusive to Papua New Guinea because some tribes practiced cannibalism, and Kuru would spread from a contaminated person to those who consumed it. There's no evidence that sporadic CJD can be transmitted from person to person. However, there is evidence that vCJD can spread from person to person, usually via contaminated medical tools (spine taps). To explain once more, vCJD was caused by mad cow disease in the U.K. It's different from sporadic CJD, but it shares similar traits. Kuru is a completely different form of prion disease and is not related to CJD. A rather poorly and unclearly made video on a rather interesting topic.
@matttheyak
@matttheyak 9 ай бұрын
Probably generated via the sponsor's AI
@Jerry-qj5fk
@Jerry-qj5fk 9 ай бұрын
That’s what I thought when I looked at his sources.
@ZirconiaGacha
@ZirconiaGacha 8 ай бұрын
I did research on prion diseases so I could write about something I was passionate about for my little speech (it was like a short version of a TED talk on something science related). I chose to narrow it down to chronic wasting disease in cervids, but I had a section on general prion diseases, since at their core they are all the same (misfolded proteins as the cause, through one form or another). From my research for something in HIGH SCHOOL, Kuru was specifically spread through cannibalism, but prion diseases in general are sporadic. While I didn't look deeply into Kuru, I did notice a few things. Different prion diseases in humans are named/categorized by small changes in spread and symptoms. Fatal insomnia causes you to be unable to sleep on top of everything else, and while I didn't see Kuru's symptoms, I wouldn't be surprised if it had nearly exactly the same symptoms as most other human prion diseases, but was identified as something different because of the unique circumstances that caused it to spread (cannibalism still occurring in Papua). He even got the idea of prions being completely indestructible wrong, unless every single other source I've seen (including some really reputable ones such as the CDC) is wrong, which say that they can be destroyed (or at least heavily neutralized) by extremely high temperatures. So while he was right about cooking not being enough, being completely unable to get rid of existing prions is just incorrect.
@magnuslunzer2335
@magnuslunzer2335 9 ай бұрын
yo that stuff caused a lot of beef back then
@vedran3775
@vedran3775 9 ай бұрын
HahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahahaHahahahahahahahahahaha
@capralmarines4043
@capralmarines4043 9 ай бұрын
💀
@WarFoxThunder
@WarFoxThunder 9 ай бұрын
LMAO
@professionaleejit5927
@professionaleejit5927 8 ай бұрын
The steaks were quite high
@kimlarso
@kimlarso 7 ай бұрын
😂
@nikeprojock
@nikeprojock 9 ай бұрын
gross i didn't know they fed cows other cows that is just unethical and demented. who thought that was a good idea
@cattoduke6286
@cattoduke6286 9 ай бұрын
It's definitely a bad idea, but how is it unethical tho? Most animals, cows included, will just eat anything edible.
@nikeprojock
@nikeprojock 9 ай бұрын
@@cattoduke6286 unethical because cows don’t know any better, like someone made that decision they don’t have ethics if that’s how they were raised
@cattoduke6286
@cattoduke6286 9 ай бұрын
@@nikeprojock exactly. Cows don't know any better, they don't have the slightest problem eating other cows at all. It's not like the farmers force feed them or sth.
@nikeprojock
@nikeprojock 9 ай бұрын
@@cattoduke6286 you are wild, that is exactly what they are doing
@CrunchyGreenWater
@CrunchyGreenWater 9 ай бұрын
People who wanted to increase their profits and/or reduce their expenses.
@bobbler2
@bobbler2 9 ай бұрын
What if someone fed human to cows would cows get mad human disease
@shivalishankersharma1562
@shivalishankersharma1562 9 ай бұрын
Parallel universe theory
@ljt3084
@ljt3084 9 ай бұрын
Nah, they get Karen disease.
@naomisherred166
@naomisherred166 9 ай бұрын
Or maybe turn into a politician 😂
@Osama-Bon-Jovi-01
@Osama-Bon-Jovi-01 7 ай бұрын
You have to feed the humans to eachother first
@The_Menendez
@The_Menendez 3 ай бұрын
retaliation
@PeiPeisMom
@PeiPeisMom 7 ай бұрын
I remember giving blood here in the US in '96, and them asking me on a questionnaire if I'd been in the UK any time in the last 10 years
@jf8138
@jf8138 4 ай бұрын
I know somebody that had Prions in his brain from a CJD. He died in 6 months after the first symptoms, but the downfall was FAST.
@Jersey.D3vil201
@Jersey.D3vil201 9 ай бұрын
Whoever threw that traffic cone at the cops is a beast. They're heavy as hell!
@davelowe1977
@davelowe1977 Ай бұрын
An ex of mine's mum died from CJD more than 20 years ago. Possibly unrelated, I remember the school kitchen having a slop bucket for all the food waste that a farmer collected every day after lunch to feed to his pigs. There would have been pork products in that bucket fairly often.
@jtgd
@jtgd 9 ай бұрын
“Help, I’ve folded and can’t unfold!”
@cloudywolf9738
@cloudywolf9738 8 ай бұрын
I remember when this was going on when I was a kid, it was terrifying.
@darkscienceyt
@darkscienceyt 8 ай бұрын
same
@rizkyp
@rizkyp 9 ай бұрын
Reusing infected beef as feed is stupid.
@ceiling_cat
@ceiling_cat 4 ай бұрын
not as stupid as your usual manager
@The1_Hellhound
@The1_Hellhound 9 ай бұрын
It's always a good day when you learn disturbing science, not because you're a psycho or something. But because you see how people fail and unfortunately lives end, but as a result, we learn from these unfortunate events and move forward with new precautions.
@therraxz
@therraxz 5 ай бұрын
That sickness is absolutely terrifying. 100% fatality and almost impossible to get ridd of. I was in england at the time and probobly consumed some of that meat, its absolutely scary to think of.
@rodrigolimatattoo
@rodrigolimatattoo 6 ай бұрын
My uncle died from this 1 year ago. Brazil, São Paulo. Doctors sent part of his brain to a research facility in UK. They confirmed the Creutzfeldt-Jakob disease . He died in less than 5 months.
@gammaarmy9547
@gammaarmy9547 9 ай бұрын
I think this might explain why Otto Warmbier died after being sent back from North Korea. He might have been fed prions which negatively impacted his healthy state, hence probably why the North Koreans stated that Otto had botulism. Besides the American student was in North Korea for a good 17 months, that's more than enough time for prions to become fatal. (He also had scans done of his brain, which had severe neurological injury and defective cells, which makes the so-called "botulism" seem credible to have prions)
@theactualegg
@theactualegg 7 ай бұрын
Moral of the story: don’t feed animals food made from their own species 😭
@tredog884
@tredog884 4 ай бұрын
Especially if the animal never eats meat to begin with.
@GiantRogueWave
@GiantRogueWave 3 ай бұрын
Prion diseases are catastrophic. Anyone who has lost a loved one to CJD understands just how devastating these diseases are.
@capoman1
@capoman1 5 ай бұрын
4:09 Phew. Glad I gave up eating humans all those years ago.
@thecapeofnohope6018
@thecapeofnohope6018 4 ай бұрын
Prion diseases can take years or decades after infection to show symptoms, you aren’t in the clear.
@nuodso
@nuodso 9 ай бұрын
Creu- in "Creutzfeldt" is pronounced like "croy", rhyming with soy, boy and Roy.
@MoolsDogTwoOfficial
@MoolsDogTwoOfficial 9 ай бұрын
“soy, boy” xd
@nuodso
@nuodso 9 ай бұрын
@sevenmillionhobbies7840Correct
@ljt3084
@ljt3084 9 ай бұрын
And Jakob is pronounced with a Y. Yakob.
@Zombieslayajay
@Zombieslayajay 9 ай бұрын
Thank you for uploading this video I have been having such a a horrible week (not a basic bad week a downright traumatizing week) and it made me so happy to see you upload
@thebeigesheep6132
@thebeigesheep6132 9 ай бұрын
I hope you are ok
@Zombieslayajay
@Zombieslayajay 9 ай бұрын
@@thebeigesheep6132 I wish you nothing but love and happiness
@thebeigesheep6132
@thebeigesheep6132 9 ай бұрын
@@Zombieslayajay having a hard time too. I'm trying. Hope things get better for u this week
@markdombrovan8849
@markdombrovan8849 9 ай бұрын
I hope next week is even more memorable than your last one!
@CountingStars333
@CountingStars333 5 ай бұрын
Duality of the net
@benmcreynolds8581
@benmcreynolds8581 9 ай бұрын
I will always eat meat and I love science but prions truly are one of the most terrifying things I've ever learned about.. To learn just misfolded proteins can cause a run away effect with in your body in a very hidden manner.. You might not know for years after being exposed.. It's the trippiest thing ever and I wish we had ways to not only treat this stuff but also treat or prevent dementia.. My grandma a few years ago succumbed to a rare form of very aggressive fast on set type of dementia.. It made me so motivated to want to help learn and study how to understand and evolve our grasp of dementia..
@Gaminguide1000
@Gaminguide1000 9 ай бұрын
at the start of the video you said that CJD increases the amount of prions being created. Does that mean everyone has prions? and if yes, how do our bodys stop it from killing us, and why does this protection mechanism not work with vCJD? Asking anyone who reads this btw, im very interested in such topics
@kimlarso
@kimlarso 7 ай бұрын
Just as all people do not get cancer not all will get folded prions or perhaps already have other prions that keep the deadly prions at bay acting like venom/anti venom
@machfassett5749
@machfassett5749 5 ай бұрын
Quick correction since I can't help myself: the prion protein itself is not the issue. Everyone has normal prions in their body, although we don't yet know their function (although, their close cousin, the doppel gene--which was discovered when we were trying to figure out the function of prions, as its structure looks very similar to that of the prion's--is responsible for making sure that (at least) the sperm gamete is made correctly. Fun! Small amounts of it is also in the brain, and when there's too much in the brain, that can also cause issues; it's believed that prions and doppels are antagonistic to each other at least in the brain, meaning they perform the opposite action of each other to keep equilibrium). The endoplasmic reticulum is responsible for making sure all of the prion proteins are folded correctly; it's estimated that as many as 1 in 10 are misfolded, and the ER refolds them. Problem is, it's extremely difficult, and one of the ways prion disease develops is when the ER is overwhelmed by too many misfolded proteins that then misfold other proteins that come into contact with them.
@capoman1
@capoman1 5 ай бұрын
5:30 At least they learned about mad cow disease and that the likely cause was feeding cattle waste to themselves. And glad they implemented testing and safety measures.
@SentryFather
@SentryFather 4 күн бұрын
Moral of the story: never eat cow from Sussex, England
@TieWolf
@TieWolf 8 ай бұрын
The way you pronounced "bison" just gave away what part of the U.S. you are from. haha My partner is from NY state and: - Bison - Documentary - Elementary are the words that drives me nuts how he pronounces them. I guess some are super regional to Western NY.
4 ай бұрын
I was living in West Germany in the late 1980s _WHEN IT BEGAN other places in Europe._ Sick and dead cows were processed and added to cattle feed, dog food, cat food and fish and fowl feeds. THAT is how it exploded. Cannibalism is never good.
@lukeahn0330
@lukeahn0330 9 ай бұрын
Lets go, it's a Dark Science upload on a Friday.
@timelessdragon8950
@timelessdragon8950 9 ай бұрын
🔥🔥
@jasonhall7491
@jasonhall7491 9 ай бұрын
TypeAI scares me more than any prion.
@eldiablo7862
@eldiablo7862 3 ай бұрын
Study of the last tribe practicing cannibalism were documented to exhibit the same neurological defects.
@orlandofurioso7329
@orlandofurioso7329 4 ай бұрын
Pigs are immune to bse, i wonder if we could study them since they are similar to us in many ways
@Stellarainn
@Stellarainn 3 ай бұрын
What if u feed beef with yhe disease to a pig?
@orlandofurioso7329
@orlandofurioso7329 3 ай бұрын
@@Stellarainn that's the thing, pigs never or almost never gor bse, mice injected with pigs that ate diseased beef did not develop the disease
@pinonpine9460
@pinonpine9460 9 ай бұрын
I just heard this guy tell me that hydrogen bonds are strong...... my man do you know what a covalent bond IS?
@beornthebear.8220
@beornthebear.8220 4 ай бұрын
The worst thing is you can't cook it out. You can't disinfect it out of the food.
@jhpratt
@jhpratt 9 ай бұрын
Please add scales to graphs. They are meaningless without them.
@Douglas_413
@Douglas_413 9 ай бұрын
🤓🤓🤓
@The_Menendez
@The_Menendez 3 ай бұрын
🤓🤓🤓
@notsojharedtroll23
@notsojharedtroll23 3 ай бұрын
​@@Douglas_413 hate 🤓 but he's right. We don't understand at a glance what the numbers may mean. I know in this context is understandablen but better not risk it just for image clarity.
@RonaldDump_real
@RonaldDump_real 4 ай бұрын
My father can not legally donate blood because he was in England during the peak of the outbreak due to CJD having the ability to lie dormant in people
@juhokleemola5961
@juhokleemola5961 9 ай бұрын
These vids never seem to disappoint. Great job.
@boogrs55
@boogrs55 9 ай бұрын
And this also shows that if people were to be seriously be pissed off by the government they could just overthrow said government
@brightlight3520
@brightlight3520 6 ай бұрын
revolution when?
@ALA9E
@ALA9E 9 ай бұрын
Why are they feeding protein to grass feeders! Their systems are not made for processing meat!
@streamerssaymyname
@streamerssaymyname 4 ай бұрын
I would like to point out at around 6:30 would be a good time to mention how there was a similar disease in goats/sheep but the disease never spread to humans. So they were working on the information they had at the time which was the history of a similar disease NOT infecting humans, and there were no similar diseases known to do so. There was a strong belief it would not infect people because it simply did not happen before to their knowledge.
@DoroteaTheMacuahuitl-Potato
@DoroteaTheMacuahuitl-Potato 9 ай бұрын
Commentary: Thank you for providing me with an extensive coverage of this subject. Observation: You claim you use AI to improve your writing. 8:29 “Public outrage rose to anger.” Maybe you shouldn’t.
@Jay-lb2ot
@Jay-lb2ot 4 ай бұрын
Great video but I disagree with one point! Hydrogen bonds are relatively weak on their own compared to ionic bonds (what’s the boiling point of salt Vs water?) however when theirs a bunch of them together, they then become particularly strong.
@ChorltonBrook
@ChorltonBrook 3 ай бұрын
‘Unprecedented protests’ + a picture of Poll Tax protesters doesn’t come across as genuine mate. There were absolutely no demonstrations over BSE. Maybe a couple of little moans about compensation by farmers that’s all
@TrioLive0
@TrioLive0 Ай бұрын
5:57 who named this bru 🙏
@flippi_flobija
@flippi_flobija 9 ай бұрын
Babe, wake up! Dark Science posted new video!
@minglifeng2862
@minglifeng2862 2 ай бұрын
‘Scientific committees were criticised for their slow decisions’ the way it has definitely gotten even worse now than back then. Every medical guideline is more concerned about ‘overdiagnoses’ and ‘overtreatment’, even now just after a deadly pandemic, that’s partially why people need to fight with their doctors for them even consider giving tests to see what’s wrong with them and just being all around dismissive
@xcoder1122
@xcoder1122 9 ай бұрын
This video ignores the true origin of BSE. That prions are formed by accident in human beings or in cattle can happen but is super rare. Yet it happens way more often in sheep, where the illness they cause is known as "scrapie". In sheep this illness is known since 1732. And the most probably cause of BSE was, that sheep parts were also processed into cattle food. That sheep are more prone to forming prions has genetic reasons and may be a cause of breeding performed by human beings. Which is enforced by the fact that some sheep species are more prone to it than others and those more prone are those that did undergo more breeding by human beings. So that's how BSE started and only from there it was cattle to cattle transmission by processing cattle remains as cattle food.
@cur1ouscatf1sh
@cur1ouscatf1sh Күн бұрын
There was an x files episode about this. There was a town of people who were eating each other (it was something about seeking immortality) and one of them had creutzfeld-jacob’s, which spread to all the cannibals. That’s where I first heard about this, and it’s really interesting to learn more about the real science behind it
@VEV-cu6no
@VEV-cu6no 9 ай бұрын
I was just reading about TSEs and Kuru. Thanks for the video!
@BaronBunny-p3x
@BaronBunny-p3x 9 ай бұрын
Why would you fed cow another cow in first place wtf?
@emilywenig4390
@emilywenig4390 9 ай бұрын
To save money of course!
@Guenter34
@Guenter34 9 ай бұрын
Thanks for another video! I always look forward to them. They're really calming and interesting!
@beginnereasy
@beginnereasy 5 ай бұрын
I'm just saying humans have been smart enough to synthesize designed life, for a very long time
@omgitzpaige2013
@omgitzpaige2013 7 ай бұрын
the timeline shows this basically peaked when my mother was pregnant with me (1995-1996) im blessed we weren’t affected
@Volundur9567
@Volundur9567 9 ай бұрын
Add to this that prions can't be easily destroyed. They remain in soil and can contaminate produce.
@mkamback
@mkamback 9 ай бұрын
I love this channel SO much. Please keep making more content like this! 🤘
@Humongous_Pig_Benis
@Humongous_Pig_Benis 9 ай бұрын
0:44 Schotland. Yesh me lad.
@someguy2135
@someguy2135 9 ай бұрын
Other reasons to not eat beef? Red meat is a type 2A (probable) carcinogen, and raising cows has the worst impact on the environment including climate change of any farmed animal. It also wastes the most natural resources like fresh water, and is the main reason why animal agriculture is the top cause of deforestation, habitat loss, and biodiversity loss. The Amazon rain forest was decimated by burning to raise cattle and to grow soy for farm animal feed. Brazil is a top exporter of beef and soy.
@normajeancaballero7959
@normajeancaballero7959 9 ай бұрын
I remember this Mad Cow Disease threat. 😨
@prions_arent_cool_man
@prions_arent_cool_man 9 ай бұрын
i just got home from school and i was teaching them about prions like every other week and i get home and find this?? HOLY BLACKFLIPPING DUCKS THAT CAN BREATHE FIRE, MY INTEREST HAS BEEN SATISFIED-
@observingrogue7652
@observingrogue7652 5 ай бұрын
Prions are the only reason why I am scared to hunt or scavenge forest animals for food, to live offgrid. I'm also scared to eat fresh water fish, in case an infected deer contaminated the river or lake I would fish in. I don't like seafood, but the reduced chance of prions being in the ocean, is making me interested. But then there's the issue of microplastics & mercury in seafood. I'm not joining the cult of veganism, because it would be very difficult to get essential nutrients, mainly found in animal products, like vitamin B12. And if & when poop hits the fan, harder then covid. Vegans will be in the same boat as diabetics, trans people, and other people who require special things, they can't make themselves, or find in the wild, like insulin, hormone therapy meds, other medication, non-animal-product B12 and nutrients you have to get from some company or lab. These groups of people are the first to really struggle during a Doomday Prepper like disaster. Insulin dosent last that long, medications expire, and I think there is alge that makes B12, but how many vegans can or will farm that? And what about the other essential nutrients easy found in animal products? Life can really suck.
@cevatkokbudak6414
@cevatkokbudak6414 2 ай бұрын
Only the %1 would survive in a doomsday scenario
@rhythm5080
@rhythm5080 9 ай бұрын
Wow I never knew before today that cows were involuntary cannibals
@Blackearbaiya
@Blackearbaiya 9 ай бұрын
Yeah i think if the cattle industry was a bit more coniderate (like why tf would they let cows eat beef) maybe prions would affect humans less
@joycebrewer4150
@joycebrewer4150 8 ай бұрын
Not a matter of "letting" cattle eat cattle. They blended bone and meat meal into rations fed to feed lot cattle. They thought it was a shortcut to get cattle to market weight faster, providing protein directly, rather than the animal have to make it from ingredients in plants.
@matttheyak
@matttheyak 9 ай бұрын
8:56 Image of 90's Australian Prime Minister Paul Keating... completely unrelated to the topic but ok.
@wentoneisendon6502
@wentoneisendon6502 9 ай бұрын
IV products in the UK are still subject to BSE screenings
@norse_cat
@norse_cat 7 сағат бұрын
This scares me more than like anything. Prions and just getting Alzheimer’s/dementia. 😢 Prions work so much faster though. It makes me want to avoid meat, even though that’s not even foolproof.
@capoman1
@capoman1 5 ай бұрын
Dude I thought the title said PRISONS. I watched the whole video thinking "wtf does this have to do with prisons?" By the caption I thought they stopped feeding prisoners beef.
@mainaccount7519
@mainaccount7519 Ай бұрын
The thumbnail kind of makes it seem like people forgoing beef was the worst part of this
@monstandalone7339
@monstandalone7339 9 ай бұрын
No insult but prions are like "I'll try spinning that's a good trick"
@jplouthelgm5156
@jplouthelgm5156 9 ай бұрын
Putting your 4-year-old daughter's life in jeopardy for a political stunt. 👍
@SylvesterAshcroft88
@SylvesterAshcroft88 4 ай бұрын
Prion's are pretty scary.
@chemist27
@chemist27 9 ай бұрын
8:55 I almost thought that this was Dan cooper , although he looks very similar. But he is Paul Keating prime minister of Australia
@ThatDepressionGuy
@ThatDepressionGuy 2 ай бұрын
Don't understand how former Australian PM ended up in this video?!
@jackbotman
@jackbotman 9 ай бұрын
The steaks have never been higher
@neptun2810
@neptun2810 9 ай бұрын
There is no cure right now, but I'm sure we will eventually figure it out. We defeated so many diseases that were once called incurable, and we did so many things that were once called impossible. One day, curing Prions will be just another thing that we just do despite our ancestors calling them impossible.
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