The potential use of proteomics for predicting relapse in patients with MDS undergoing alloSCT

Guru Subramanian Guru Murthy, MD, Medical College of Wisconsin, Milwaukee, WI, discusses the potential use of proteomics to predict relapse in patients with myelodysplastic syndromes (MDS) undergoing allogeneic stem cell transplantation (alloSCT). The study identified two proteomic signatures, the hallmark complement pathway and the hallmark allograft rejection pathway, that were overexpressed in patients who relapsed, highlighting the potential of proteomics to provide insights into disease biology beyond genomic alterations. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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