The Three Horrifying Stages of Syphilis

[@barryrichards2320]

I subscribed as soon as I read Dark Science.

[@kubikim]

I read Dark Science as I subscribed as soon.

[@metallizationofficial980]

i did not

[@atha6632]

bruh what

[@liquidice2783]

Bruh I didnt even know I was subbed , I went to go try and sub again 😂😂

[@michaellavery4899]

I was subbed in favour of a good player.

[@Flammenengel1]

Another interesting factoid about Syphilis: back in the days before Penicillin they used to infect people suffering from late stage Neurosyphilis with Malaria as a cure. The intense fever cycles and highly stimulated immune system would kill off the bacteria and the Malaria could then be taken care of afterwards. While they used relatively mild Malaria strains the method obviously still came with risks, but was better than nothing. If I recall correctly the guys who did it first even got a Nobel prize for it.

[@benl9776]

That´s a very interesting fact, do you have a link to the source?

[@Hollandhallock]

The source is: I made it the fuck it

[@Flammenengel1]

@@benl9776 Posting links doesn't seem to work but you may google them yourself. A historical source: Redvers N. Ironside, Jan 1925, "ON THE TREATMENT OF GENERAL PARALYSIS BY MALARIA INOCULATION", Br J Vener Dis.; 1(1): 58-63. doi: 10.1136/sti.1.1.58 A more recent one: Daey Ouwens, Ingrid M et al. “Malaria Fever Therapy for General Paralysis of the Insane: A Historical Cohort Study.” European neurology vol. 78,1-2 (2017): 56-62. doi:10.1159/000477900 If you prefer them, there are also articles on Wikipedia. For full clarification: originally I learned about it through my microbiology prof, who mentioned it as a fun fact while we were mainly covering other diseases. For that I don't have an easily accessible source of course, other than my memory and the notes I took.

[@kami2848]

@@Flammenengel1 what a legend. thank you L for the guy above you lol

[@skarloeythomas5172]

@@benl9776 He said factoid, meaning it’s false.

[@Haydenerich]

I had syphilis years ago. I don’t remember having any distinct symptoms, so it went undetected for a couple years. I started having health problems after those years. My joints and body constantly ached. I had lesions all over my legs, and a gumma (tumor) in my right eye. After going to countless drs with no explanation of my symptoms, my dermatologist took a biopsy of a sore on my leg. Not sure how she figured it out, but she ran a test for syphilis and was positive. When I went to the hospital, they did a spinal tap and confirmed that I had neuro-syphilis in my spinal fluid. The dr told me i couldve had organ failure in a matter of weeks. I had to have a PICC line (which is an IV that thread through the arm veins to above the heart) which was connected to antibiotics that would continuously provide medication. I had to wear that for nearly a month. Aside from losing my vision in my right eye, thankfully I made a full recover without any other serious damage.

[@spiritmatter1553]

That’s spelled PICC line. (Medical transcriptionist here.) So glad you got a diagnosis in time.

[@williebgoodtoot]

Damn

[@Ami-jc2oo]

Do you have a sick eye patch then? Also glad to see you mostly recovered.

[@JohnSmith-fq7hj]

​@@Ami-jc2oolol I used to want to lose an eye just so I could wear a cool glass eye (like bill the butcher in gangs of new York) or eye patch lol.

[@grahh7234]

That’s mega cap bro u would’ve been cooked. If u actually got it

[@bernardhughes8598]

Over 40 years ago, I woke with a total body rash. The hospital suggested secondary syphilis and sent me to the nearby special clinic. They immediately spotted that it wasn't. It was decided that it was a severe allergy to the penecillin that I had been prescribed for a very sore throat. Good job the first hospital didn't pump me full of penecillin to cure the syphilis I didn't have.

[@u4riahsc]

Around 1968 when I was in high school I contacted mono and had penecillian shots that caused a rash all over my body, even in my mouth.

[@dinacharlayne1912]

They have to test positive for it they say before they give medicine but we saw some youtube videos in like san francisco saying give them the medicine... but san francisco's a world away from oklahoma probably.

[@KatieDe_G]

I had hand foot and mouth as an adult but thought I had Syphilis due to my hand and foot rash lol

[@GayHaruspex]

Omg, someone else with a penicillin allergy! You’re the only other person I’ve met with one, lol

[@bernardhughes8598]

@@GayHaruspex One of my 3 daughters is also allergic. She is the only other person I know.

[@gerardosalazar161]

The lady at 00:35 is not a victim of syphilis but a lady who died in a fire and her picture was taken as a Memento Mori by her family; I believe that her memory deserves respect even if we don’t know her name. May she Rest in Peace.

[@chimom7112]

Not that i check out all the syphilis post, but i have seen her in one before. Nice to know the truth and im sure this lady would have appreciated it also.

[@DarkStarHearts]

Wow, thanks for posting this comment and sharing the info

[@Nuts2Big]

That’s so nice of you to pay her respects I didn’t know but may she Rest In Peace as you said.

[@karyannfontaine8757]

Thank you for that information. Yes, RIP dear lady.

[@gordonross3270]

Source?

[@philc.9280]

I remember back when I was in my residency we had an elderly gentleman suffering from cognition issues. Just about everyone wrote him off as having early-stage dementia or Alzheimers. My preceptor astutely ordered an STD screen just as a long shot. The guy was positive for syphilis. He was in his 70's so he probably had the tertiary stage for 30 years. One of many facts ingrained in my head all these years.

[@amyyoung2804]

I've also seen a couple cases of primary syphilis as a nurse working at the VA hospital. Big injection of Bicillin did the trick.

[@cintarocko5095]

Yuck

[@windsofmarchjourneyperrytr2823]

I heard of a mam who came up w herpes after not touching a woman for like 30 YEARS.

[@drbigmdftnu]

I had a similar case in my residency. Couple in their 80's, wife was showing dementia signs. Did the workup and she was positive for syphilis. How are we going to tell these nice old folks who had been married 60 years? When we told them, they were quiet for a few moments. Then the husband mumbled "oh... that old thing" She apparently had been partially treated in the past but never cured or completed. CSF showed likely neurosyphilis. Thankfully, it is still a sensitive organism and infection pretty easily eradicated. The problem is the immune system gets so wigged out - the systemic inflammation and vasculitis may persist. Just like Lyme, also caused by a spirochete. It becomes an autoimmune disease.

[@donnawoods7204]

Had several tertiary syphilis patients in the nursing home, in their 80-90s. The dementia was much worse than other types

[@OpEditorial]

Fun fact: the grotesque rotting features and unpredictable sometimes violent behaviour of late stage syphilis sufferers have directly inspired the zombie genre of film and fiction.

[@albusnightspring8057]

Zombies come from VooDoo legend though as far as I know

[@ecvjtv2778]

Rabies could also be a possible inspiration

[@stillhere4165]

​​he wasn't saying syphilis was the progenitor of zombies, just that it inspired elements of them. Both takes are true.

[@BethBurns68]

@@ecvjtv2778 , but does rabies cause rotting flesh? The images in this video certainly made me think of zombies, poor, poor people.

[@ecvjtv2778]

@Elizabeth Burns Not that I know of, but it causes foaming around the mouth due to difficulty with swallowing. And more importantly, it causes anger and insanity. It also mainly gets spread through bites. These are the factors that could be possible inspirations to zombies

[@daintybeigli]

I work in a rehab profession and had a client with neurosyphilis. By the time he was diagnosed and treated with antibiotics, he had significant brain damage. He appeared to have been infected from his mother in utero, but no one knew as he had been put up for adoption. He was only born in like 1975. I’ll never forget him.

[@renato7184]

Poor guy

[@annmurphy8440]

I hope life has been kind to him to be born with such a terrible affliction through no fault of his own life is hard enough for some people some people believe that we choose the life we want to live before we are born what a crock of shit Ann Murphy Ireland

[@beandon9074]

My god

[@mycolliesandme268]

@@markmower1746 you don't have to be gay to get it. It's transmitted with both sexes

[@mycolliesandme268]

@@markmower1746 they said he was infected by his mother. But you say he was gay.

[@Amy_the_Lizard]

Would like to point out that with the current rise in antibiotic-resistant syphilis strains, I wouldn't consider it "nothing to worry about," just less of a worry than it was in the past

[@phils4634]

Fortunately still very sensitive to benzathine penicillin (1.8g single dose, usually as 2 x 900mg injections, one for each bum cheek!) If penicillin resistance does become really established, we're up the creek, especially seeing as Neisseria gonorrhoeae is now turning up with "significant" Ceftriaxone resistance (and cases are also on the rise for this one too!)

[@Amy_the_Lizard]

@phils4634 Absolutely! We had a two whole days of class focused on antibiotic resistant gonorrhea in my evolution of infectious diseases class, it's scary stuff - especially that one strain there's only been a couple cases of that was only susceptible to one medication

[@phils4634]

@@Amy_the_Lizard Whilst Syphilis and Gonorrhoea get all the limelight, Mycoplasma genitalium's the one to keep an eye on. Doxycycline resistance is now commonplace (especially for strains arising from SE Asia), and with the loss of Pristinamycin, we've only got Minocycline (far less effective) or Sitafloxacin (which is difficult to source, and pretty costly). I'm Australian, and you might not be surprised how many older Gents nip "over there" to find "Mrs Right", and come back home with "unexpected passengers" 🙂

[@2bfrank657]

Absolutely!! I cringed when he said that. Such a complacent attitude. Antibiotic resistance is a huge problem for mankind.

[@KadenHartley]

Sorry i keep using evolve points on my bacteria in Plague inc.

[@CastielLovesIt]

My best friend somehow got a dose of it & didn’t realize what it was until he developed full-blown tertiary syphilis. That was in the 90’s. He’s been severely disabled ever since.

[@SilverSurfer-x3z]

Castiels Granny Somehow got a dose of it? It's pretty clear how he must have got it. Sad for him though.

[@zagsz8631]

​@@SilverSurfer-x3zlmao

[@LittleKitty22]

@@SilverSurfer-x3z Why sad? If he can't be decent and stay with one woman, he deserves to pay the price.

[@Mikelaxo]

​@@LittleKitty22 Getting an STD doesn't necessarily mean you're promiscuous

[@McYeroc]

​​​@@LittleKitty22people have contracted syphilis in utero before they were even born and only found out when they get into the 3rd stage of syphilis when in there 20s or 30s. Get a grip.

[@andrebartels1690]

My uncle died from syphilis. We never got to know why he didn't get a therapy. We found out he had syphilis when it was too late to rescue him. It was a nasty death. May he rest in peace.

[@Coco-xw3wp]

One of many Disgusting diseases European or Caucasians has and wipped out race's of people with their Disgusting hygiene add filth!! I believe it's karma for all the evil deeds these demonic entities brought to the human race period! Not only that 98% if them suffered from the black Plague!

[@Parker05]

were any other family members infected?

[@andrebartels1690]

No, there were not. That's probably because syphilis is not contagious as a flu. You need to have sex or do something that's as intense as sex.

[@jacquelinewilliamson8933]

Maybe he was to embarrassed to do so sadly this still happens.

[@tamekabatson1998]

Sorry for your loss 😢

[@chrisb9365]

Worth mentioning is congenital syphilis, e.g. syphilis you are born with due to mother being infected. CDC actually says that there is rise of syphilis in the recent years.

[@melitopiia4730]

@captain awesome Source?

[@Niosesore]

@@captainawesome12345 actually, it's raising among men (mostly homosexual men) and decreasing among women lol

[@z1u512]

@@Niosesore Source?

[@Niosesore]

@@z1u512 C. L. Cellum Sexually transmitted infections and HIV: epidemiology and interventions, M. E. Kent and F. Romanelli Reexamining Syphilis: An Update on Epidemiology, Clinical Manifestations, and Management

[@Niosesore]

@@z1u512 It's mostly US/EU centric, it's different in African and Asian countries.

[@daverose8082]

Having nursed patients with limbs rotting away from the inside due to the latter stages of GPI (General Paralysis of the Insane) I can attest to the devastating effects of Syphilis.

[@boobalooqwe4687]

that would be an awesome punk rock band name

[@TokyoAzzA]

I feel great sympathy towards the people who suffered horribly from this disease in our history, and great appreciation to the medical scientists who developed the treatment preventing most people in the future from suffering the same fate.

[@SrMikicas]

Don't you worry. In the future there will be new diseases to deal with, either from new environments we visit, new problems we create or worse man made diseases designed to destroy or incapacitate a population. Hopefully we grow beyond this but I think we will have them as long as humans are humans.

[@seanriopel3132]

Plenty of people still suffer from it in poor communities around the globe.

[@FreeSpirit47]

That's a compassionate stance. The world of 2023 has its own problems. Obesity is one of the worst.

[@wansworld27]

I think its a reminder to keep your pants on, rather than freely sharing the love around if you know what I mean.

[@FreeSpirit47]

@@wansworld27 I doubt that love had much to do with it. Lust, yes. Love, no.

[@indaboyd7791]

I was a caretaker for a lady who had tertiary syphylis infected by her husband who received it in the korean war. She died early unfortunately and there was nothing they could do abt it except palliation for her discomforts.

[@lauracarnes4007]

God bless her and all the good and faithful women who have been infected by cheating scumbags. Her husband didn't get syphilis by eating some bad Kimchi. He was banging prostitutes.

[@stephaniehowell1109]

She trusted her husband not to cheat, and bring home something that would harm her. So many wives do. Smh. May she rest in Peace.

[@megrocks3026]

@@stephaniehowell1109you know he could’ve gotten it from war. Theres blood, injuries. Everyone’s blood is mixing and thats the least of their worries in a war setting

[@BruceLee-fd7uw]

​@megrhighly unlikely ocks3026

[@Prismalpink]

So tired of cheating military husbands.

[@CH3CH2OCH2CH3net]

One of my favorite composers, Franz Schubert, died from syphilis at age 31. Somehow, he managed to compose 1,000 pieces of music. He wrote one of the greatest piano sonatas of all time the month he died from the disease (the B-Flat Major Piano Sonata, D. 960).

[@whome1299]

That is my favorite. 🤘

[@Filthypagan]

Wrong he died of typhus

[@Xinjiekou_新街口_Station]

@@Filthypagan Was never much of a fan of his....

[@coffeemetro]

I love Schubert!

[@StoutShako]

I'm looking it up as we speak. Thanks for sharing.

[@kylieknight2365]

Al Capone also infected his wife who passed it onto his son (sonny) in utero and his son was born deaf and what appears now to of also been some sort of brain damage. But Mae for some reason didn’t seem to be affected by the disease and passed away at 89 in a nursing home and sonny passed in 2004

[@stefanrothe8622]

Of?

[@nobbynoris]

I heard that story. Capone didn't seek medical treatment because he was worried his wife would find the doctors' bills and realise he had been playing away from home . . . Mrs Capone must have been one frightening woman, that's all I'm gonna say.

[@chervilisbetterthancilantro]

And maIes blame women for in utero contraction. All the stories prove maIes to be the cause.

[@NotMykl]

@@nobbynoris What I heard was he was afraid of needles, nothing was ever said of him being "afraid his wife would find out."

[@Mikelaxo]

​@@stefanrothe8622 I think they mean "have". I also got brain damage reading that.

[@SnoopReddogg]

Funny story: My neighbour worked at a rural nursing home in Australia. I remember her telling me that whenever any elderly gentleman moved in, if they were WW2 veterans, they'd be tested for STDs. The irony was some of these men where pillers of the community, from some of the most respected families in the district and genuine proper gentleman. But sure enough, a large percentage of them also tested positive for a dose of clap and pox that they pick up during the war.

[@jackkraken3888]

A hero on the streets a beast in the sheets..

[@jeffcombs2950]

It's also estimated that Allied soldiers (gentlemen) committed 100,000 rapes in Europe during the war.

[@calonarang7378]

You also have sex workers Australia, so it should be more common, lol

[@sakabula2357]

@@jeffcombs2950 mostly Russian??

[@zacharymcdonald6323]

@@jeffcombs2950 Only a hundred thousand after years of conflict with 10s of millions involved? 144k got forced upon in America in 2021 alone guy.

[@nirvana5902]

You've ticked every checkbox I had at the end. I'm a med student, but a lot of the time studying becomes overwhelming. Videos like this reignite the passion in me to try and become a better physician & hopefully acquiring such knowledge in the future!

[@quantumblurrr]

Ok

[@jordanlucien426]

Hey imma be real with anyone who sees this, I caught syphilis literally a week before I left for navy bootcamp and thankfully they caught it in such a early state the penicillin shot in the ass hurts and the anxiety of me accidentally passing it on to another person killed me for weeks so please wear protection (thankfully to my knowledge I didn't spread it to anyone and the person I caught it from never informed me at any point in time so definitely watch where you're sticking your stuff at)

[@AR15andGOD]

You could just exercise self control and not have sex with people you don't care about at all.

[@valeriopippo3370]

@@AR15andGOD Username checks out

[@terminatorofsimps8255]

@@valeriopippo3370 What he is saying is correct. If people kept theyr pants on; instead of doing it with the first person they see on the street; deseases like syphilis would be extinct.

[@iidentifyasaa-10warthogbrr10]

@@valeriopippo3370 I see nothing wrong in what he said.

[@marktwain2053]

@@terminatorofsimps8255 If guys would keep their dicks out of other guys assses, there would be no AIDS, but that doesn't keep them from pushing the lifestyle, now does it?

[@thatchick721]

This reminded me of the Tuskegee experiment :( An institution in 1932 did a study on syphilis. They got a big group of black men I think like 600 and told them they were treating them for “bad blood” but they were actually injecting them with syphilis. They weren’t informed of the experiment but they were told that in exchange for participating in the study they would receive free meals, free medical exams, and burial insurance. Even after they developed a treatment for it, the men who were infected In the studies were not offered any kind of treatment. The people conducting the studies wanted to track the full progression of the disease and so they would study the men until they died and then preform autopsies to gather more information. It’s horrible and unethical.

[@linenflaxen6467]

What happened to the institution? Isn't that illegal?

[@theduder2617]

@@linenflaxen6467 Today, yes that would be extremely illegal. Well, more likely to result in criminal prosecution. But in 1932, although "freed", African Americans were still treated as fodder. They had little to no rights, and were often used in unethical experiments, if not outright chased down and murdered. Sadly, the aforementioned "syphilis study" continued until 1972 when word of the horrendous "study" became public. The "institution"... now considered a national historic landmark for other supposed reasons.

[@kimbella1452]

So true! It's horrible how they used these black men to experiment on!!!🤬

[@rogervincent8314]

@@linenflaxen6467 look up Tuskegee experiment

[@celestebell9992]

Yes the true story is told in the movie Miss Evers Boys..

[@Lela-plants]

Back in the 90s everyone admitted to hospitals here in Louisiana had to have a syphilis test. (We we’re in the midst of an epidemic of it)The theory was that we could catch people and treat them while they were admitted and also start the process of contact tracing. My mom said when she had me in the late 60s, they wouldn’t admit her without a chest x-ray so I suppose TB was big then. Lol Fun fact, you also used to have to have a syphilis test to get a marriage license. Same reason I guess, trying to stop a easily transmitted disease.

[@MsElizaRae]

They need to bring back that std test before marriage rule lol...maybe even dna run downs 😂

[@sarahgilbert8036]

Sadly, there's no test or ruling to limit stupidity from being passed on 😢 (general remark, not aimed at anyone in particular).

[@donnastormer9652]

I lived in New Mexico and when I got married in 1970 I think it was we had to have a blood test for syphilis before we could get a marriage license

[@rudolphvalentinoconnection8298]

STDS including syphilis is running rampant in Lousiana...a GOP governor interferred with Planned Parenthood which was the only place offering STD services to people who needed it and didn't have any other access. That is the type of shortsighted, religious nonsense that is on the table for the whole country in the future if these people regain control...

[@coloradogirl9913]

Yes, I was married in 1989 and I was required to be tested, but not my husband?! He didn't have it, But how rude and sexist were the laws!

[@ds_the_rn]

I’m an adolescent psych RN. One of my 15 yr old patients has all the STDs, including syphilis. She was trafficked for sex. And here I thought the sore on her mouth was because she got popped by her pimp. I don’t think syphilis is making her mentally ill. Hopefully we caught it in time.

[@kugelschreiberzusammenbaue3585]

what do you mean by 'all the STDs' How many are there ?

[@MonsterShiet]

THANK YOU taking care of those kids

[@abjectmadness1111]

That is heartbreaking, but also makes me so mad. I genuinely cannot explain how horrible that makes me feel. That poor girl.

[@richardlyman2961]

@@abjectmadness1111Poor clients too they also got the stds from her

[@ep_got_the_sauce]

​@@SolisIlangaAll those are highly treatable I feel for her. Herpes is the worst one in my opinion.

[@mikep9312]

The Al Capone case was really weird, guy seemed like he was the happiest he'd ever been in his life when it started affecting his brain.

[@Dustparticle000]

Yeah no sane person goes fishing in there swimming pool......

[@krispynachos9980]

So insane he forgot to do his taxes.

[@mattr.1887]

He had money and women, of course he was happy.

[@barnacleboi2595]

Ignorance is bliss, of course. If your brain was damaged and you reverted back to a childlike mentality, you would also be happy all the time since you can barely think rationally.

[@KanyeTheGayFish69]

@@mattr.1887 syphilis doesn’t make you happy

[@ExtaTer]

The sad thing is that there are no reliable tests for neurosyphilis in 3rd stage, especially one that was incompletely treated before. The RPR, VDRL tests are negative due to treatment, both in blood and in CSF. The treponema-specific tests are all positive for life and don't tell you anything new after you had syphilis. The only way to detect a remaining syphilis in CNS is to compare the antibodies in CSF and the blood - if they are more in CSF, then you have "intrathecal" production of antibodies in CNS and neurosyphilis. Most doctors in US don't know about this test, will not do it. There were patients with strokes in which all current tests show negative for neurosyphilis, yet they had it because their CSF was able to infect rabbits. Extremely sneaky and nasty disease, similar to Lyme. People still die from it because doctors underestimate it and have no tests for the more advanced stages.

[@SQUAREHEADSAM1912]

Third stage syphilis is still fatal, as it usually causes sclerosis or dementia, or sometimes both.

[@zayd7282]

Is possible for someone to have primary stage symptoms (chancles) but never secondary stage (rashes) and the only treatment they got was physical removal of several chancles by a dermatologist?? Could the desease skip stage 2 and progress to advanced stages ?

[@SQUAREHEADSAM1912]

@@zayd7282 it’s not, just the three stages plus the 30 year dormant stage, death is usually not the syphilis itself but the complications it increases the chance of. Usually it’s either heart problems, bone rotting away, sclerosis and or dementia (dementia is most common.) , and multiple other can be brought on by syphilis too, but it’s mainly those. Some infected though can live totally healthy long lives without ever dying from it, the only down side in that case is being a carrier.

[@zayd7282]

@@SQUAREHEADSAM1912 thx for answering. So the desease can skip stage 2 completly and advance to latent and tertiary? The person possibly contracted the virus and had the stage 1 symptoms (the sores on the genitals which were all scraped off by his dermatologist but never experienced any symptoms after that (no stage 2 rashes or any other obvious symptoms for 20 years so far)...and if the deasease can skip stages what should the person do to avoid any possible tietary stage damage? I appreciate if you can get me again on this question.

[@SQUAREHEADSAM1912]

@@zayd7282 well it’s not possible to skip any stages. But before there was a cure, the survivors of the disease all survived because the dormant stage never ended, usually if the dormant stage lasts longer then 30 years you’ll not likely to die from the third stage. Once thethird stage causes dementia or sclerosis it’s pretty much a death sentence, as too much harm has been done to the body. Back then the way to avoid getting it was to play it safe and use a condom.

[@benjaminwilson4558]

Very informative about a curious topic so many of us have unknowingly been associated with. My grandfather died in 1934 at age 36. Doing research his Death Certificate read :Cause Of Death: Spinal Lues.(?) ( Syphilis) He contracted it in WW 1 and died in Tertiary Stage 14 years later. Relatives-unknowingly stated he died of severe dementia.

[@kaeosfactory]

This was extremely well presented and detailed. Please do a video for every single STD on the list.

[@donaldpiper9763]

This is what’s wrong with Trump .

[@greenapetranslord4870]

​@@donaldpiper9763you have a severe case of TDS

[@Kittyxoxo]

actually im glad i stumbled over this piece, im doing a thing on microbiology and I like that you found actual spiraling cells in motion to see how they transfer and the comparisons you did on the skin, i got to understand it better and know why they are like that, i appreciate this video, very helpful indeed!

[@TheDeadPirateBob]

It’s certainly not nothing to worry about, mostly because syphilis can go undiagnosed for many reasons. It is known as “the great imitator” because it can mimic other things. Many patients, whose syphilis was discovered later, were often too shy to go to the doctor. A painless legion that resolves quickly does not seem concerning, especially in a country where healthcare can be expensive. The subsequent rash also goes away and is often detached from the memory of the painless chancre. This is why education is important. I felt this video was about 95% of the way to being a perfect introduction. Besides a possibly greater emphasis on getting screened if you have the symptoms. Overall, well done.

[@jeffmunroe8210]

I had syphillis for about 6 months. Only for so long because of a misdiagnosis by the doctor I saw. I was rotting away and it hurt so bad just to go number two. I had bloody stool and I couldn’t sit right on the couch or chairs. I was in excruciating pain and my mouth was soooo dry. I had cuts on the insides of my cheek, a sore on my lips, and my nose was constantly bloody.

[@calvinm1866]

How did you get it?

[@jeffmunroe8210]

@@calvinm1866 I had unprotected sex with a woman I didn’t know had it.

[@jeffmunroe8210]

@@calvinm1866 I don’t think she knew at the time.

[@jeffmunroe8210]

@Erathostenes Idk. I had it for like6 months and it just gradually got worse.

[@UnapologeticAilurophile114]

​@Erathostenes secondary, when the rashes and painful lesions appear. That's why if you discover a shankre, a painless odd looking zit on your mouth or genital area, don't delay go to the doctor immediately!

[@Uajd-hb1qs]

I wonder if modern zombies was inspired by some syphilis victims. Someone stumbling around, possibly lashing out occasionally, growling or barely speaking from increasing brain damage and resembling a rotting corpse from the severe scarring caused by vascular damage.

[@cypherusuh]

Nah, rabies is more likely

[@hangfire5944]

@@cypherusuh why not both?

[@Uajd-hb1qs]

And so the zombie virus was born

[@SgtTeddybear66]

I think the bible contributes to the idea of zombies as well. In the bible, it explains that during the tribulation of the world, where Gods wrath is poured out, people will seek death, but will be unable to die. They will be forced to live.

[@Uajd-hb1qs]

@@SgtTeddybear66 I’ve heard of that. I’ve also heard the second coming of Jesus will make the dead rise from their graves but I’m not sure if that was in any Christian scriptures.

[@the_burning_barrel]

I stumbled across this video by chance and my lord was i hooked subed instantly and i'm now binge watching your content.

[@Ydce1891]

I had no that it was so horrible. My great grandpa died of complications from syphilis. Apparently after moving here from Norway he had an affair. My great grandmother eventually tested positive for it but by that time we had medication fortunately. Cheating is terrible and he definitely paid the price for it but, I never understood how much he suffered 😢❤

[@krispynachos9980]

Should've worn a franger

[@Dustparticle000]

Learnt his lesson in the afterlife...probably.

[@Ydce1891]

@@Dustparticle000 is that really appropriate? You’re going to learn your lesson as well one day.

[@dinacharlayne1912]

with std's like this we have no patience with cheating men. and promiscurous men.

[@Prismalpink]

Karma exists.

[@trex3003]

A spirochete bacterium like in Lyme disease. In Lyme, the spirochete also protects itself once it enters the bloodstream and the story gets worse. Could you cover the Lyme Borrelia Burgdorferi please? It's like a creature from a horror movie.

[@teresaalmedina2510]

That's an excellent suggestion, and I hope they do because I'm very interested. That's actually how I found this video

[@jenniferlloyd9574]

I still have the feeling that Lyme is a Govt "gain of function" spirochete. Around the same time Lyme began to be noticed, veterinarians were observing and enormous increase with tick infestations on animals. Ticks are much more prolific than they were 50 years ago. Now, you might see an animal literally covered and suffering extreme anemia. Google... interesting that the Lyme vector has also gained function.

[@igostupidfast3]

on a similar subject he should also do video on hoq the Lone Star tick can cause allergies to red meat in human too

[@ReptilesGeniales]

My sister had Borrelia in her teens and my daughter got Borrelia when she was less than 10yrs old! Thankfully the doctor we went to actually admitted her lack of knowledge about the symptoms my daughter displayed, so she asked a senior doctor at the clinic for a second opinion and the answer was that she absolutely had been infected with Borrelia. Thankfully my daughter got the correct treatment right away.

[@ktmggg]

@@jenniferlloyd9574 And the increase of ticks could also be due to climate change. Milder winters and warmer summers cause almost all insect populations to increase. I live in the Pacific Northwest and have seen ant, cockroach and spider colonies increase to levels that had only been seen in the Southern U.S. Not everything is a conspiracy.

[@linriddles3336]

9:36 ii nursed a lady whose husband was treated for this disease but refused to tell her. His infidelity and gross lack of decency left her scarred for life.

[@marcuscicero9587]

another lovely situation I could've easily found myself in during my younger years. I am truly blessed for having avoided so many calamities in my life

[@NetanyahusBestFriend]

Easy when you never get laid lmao

[@quantumblurrr]

Lol I’m so grateful you survived your boring life long enough to self flagellate on youtube

[@Bot1.0-v3]

My ex at the time had this and gave it to me but Fun fact: syphilis makes you lose hair EXTREMELY fast…as well as making your face shut down…trust me I’ve had this…the hospital I went too when I was still in the primary step couldn’t find this in my blood it was months later after it sat in my body for months that a clinic I went too after I almost lost sight in my right eye took my blood and found it and said to act quick…a year later my hair is fully grown back and I’m cured

[@kars6026]

Why ex? Why don't you marry her?

[@gelatinousglob8521]

holy run-on sentence batman

[@Bot1.0-v3]

@@gelatinousglob8521sorry sorry 😅

[@Bot1.0-v3]

@@kars6026cause she wa sleeping around

[@darthshaggy9697]

Could u cover the dark science behind rabies or ebola?

[@shefamursalinda4001]

this please🙏

[@darkscienceyt]

I'll float the idea to my patrons. They vote on all my video topics

[@domonickmatheson5080]

@@darkscienceyt also do a video on tetanus

[@pamelak7924]

This please

[@RandomPerson-hd6wr]

Are you implying that rabies is man made?

[@annnichols3091]

When I was a medical librarian, I learned this limerick about syphilis: There once was a man from Bombay, who thought that the "syph" went away, so now he has tabes and saber-shinned babies, and thinks that he's queen of the May.

[@tamekabatson1998]

Oh wow 😮

[@rajr1032]

😵

[@JeffKopis]

I once knew a girl from Centralia Who contracted VD in Australia Got infected in Sydney It damaged her kidneys Now she drips from her genitalia 🤣 I dreamed that up about 25 years ago, for a friend from Centralia, WA

[@johntumahab323]

The fact that such a highly specific bacterium needs such stringent conditions to survive and thrive yet still infects millions each year should tell you what horn dogs we are as a species.

[@JR-gh8lp]

Excellent video! Short but rich with interesting facts, read in a steady clear manner

[@chateaupig826]

Yeah , the fact it lies dormant like that . Microbes are so intelligent . It's a battlefield . Look how it changes a protein to evade detection by our antibodies .

[@uneedpuns1713]

anatomy of neck snapping? the one where a human turns a person head backwards or partially and why it does kill them as people can be paralysed neck down

[@DaveTexas]

That one’s super easy to understand. When the spinal cord is severed near the brain stem, autonomic functions like respiration stop functioning. When you cannot inhale, you die quite quickly - although not instantaneously like you see in movies. Severing of the spinal cord lower down causes paralysis; the location of the break in the spinal cord determines how much paralysis the person suffers. The higher up the break, the greater the paralysis.

[@miketrissel5494]

Speaking of having questions answered ... how would the first case of Syphilis have come about? It can only grow in humans, it is transferred from human to human. This is a question I have been asking for 60 years, after my grandfather in his 70's, contracted it from a blood transfusion at a VA hospital in Cleveland.

[@2degucitas]

Really! The origin is a puzzle. It had to come from somewhere!

[@Madamchief]

Probably zoonotic mixing of blood like lots of other parasites

[@mustang8206]

If you believe in evolution another bacteria in our bodies must have mutated. If you believe in the Bible then it must have appeared after the Fall in a human

[@roswaldwalton1147]

I can't say I'm aware of the origin of the virus but the body of a young male was discovered in Pompei, he had obvious signs of the virus but also had obviously been very well taken care of by his family. So, it's been around a lot longer than people believe.

[@pandamakeuppics7772]

Aliens

[@tylerrjohnson68]

A close friend suffers from brain atrophy from having syphilis It reduced him to an eight yr olds mentality.

[@hellohej5525]

That's tragic

[@Parasiteve]

is he at all aware of what happened to him now that he's like that? like does he know his brain is that of an 8 year old now?

[@tylerrjohnson68]

@@Parasiteve yes, he is well aware of what happened to him. He has bouts of depression because he knows he's diminished

[@SocksWithSandalsEnjoyer]

That's awful, I'm so sorry. I hope he's living life as best as he can, even though it must be very difficult.

[@Wa3ypx]

That would be akin to Alzheimer's

[@PoeLemic]

Thanks for showing me about this disease syphilis. I was wondering because my father has it, and they said they couldn't cure it for because they didn't catch it early enough.

[@karyannfontaine8757]

How sad for you and your father. I will bet there are many people diagnosed with dementia who are affected by the third stage of Syphilis. Senior people are so overlooked.

[@SQUAREHEADSAM1912]

Unfortunately stage three syphilis causes severe rapid onset dementia. Usually resulting in death within 4-6 after dementia is first active.

[@1SpicyMeataball]

Did he bang a Vietnamese hooker?

[@susanmorgan4151]

I'm sorry to hear this. I pray that you will have help with your father.

[@ITACHIshinden89]

Not trying to be offensive by asking this question on you? But are you also tested positive for syphilis? Because in my knowledge a parent can also spread syphilis to their son/daughter if they get syphilis

[@RickoH_NZ]

The aorta is the main artery that carries blood AWAY from your heart to the rest of your body (not into the heart as stated in this video). The blood leaves the heart through the aortic valve. Then it travels through the aorta, making a cane-shaped curve that allows other major arteries to deliver oxygen-rich blood to the brain, muscles and other cells

[@JonSmith-cx7gr]

The neurologist Dr Oliver Sacks (Portrayed in the film Awakenings by Robin Williams) recalled in his book, 'The Man Who Mistook His Wife for a Hat and Other Clinical Tales', the case of a woman aged 85 who had suddenly become more lively and funny and young feeling. It was discovered that she had contracted syphilis some 65 years before and the 3rd stage had just begun. I have copied it below if anybody is interested: Cupid’s Disease A bright woman of ninety, Natasha K., recently came to our clinic. Soon after her eighty-eighth birthday, she said, she noticed ‘a change’. What sort of change? we queried. ‘Delightful!’ she exclaimed. ‘I thoroughly enjoyed it. I felt more energetic, more alive-I felt young once again. I took an interest in the young men. I started to feel, you might say, “frisky”-yes, frisky.’ ‘This was a problem?’ ‘No, not at first. I felt well, extremely well-why should I think anything was the matter?’ ‘And then?’ ‘My friends started to worry. First they said, “You look radiant- a new lease on life!”, but then they started to think it was not quite-appropriate. “You were always so shy,” they said, “and now you’re a flirt. You giggle, you tell jokes-at your age, is that right?” ‘ ‘And how did you feel?’ ‘I was taken aback. I’d been carried along, and it didn’t occur to me to question what was happening. But then I did. I said to myself, “You’re 89, Natasha, this has been going on for a year. You were always so temperate in feeling-and now this extravagance! You are an old woman, nearing the end. What could justify such a sudden euphoria?” And as soon as I thought of euphoria, things took on a new complexion ... “You’re sick, my dear,” I said to myself. “You’re feeling too well, you have to be ill!” ‘ ‘Ill? Emotionally? Mentally ill?’ ‘No, not emotionally-physically ill. It was something in my body, my brain, that was making me high. And then I thought- goddam it, it’s Cupid’s Disease!’ ‘Cupid’s Disease?’ I echoed, blankly. I had never heard of the term before. ‘Yes, Cupid’s Disease-syphilis, you know. I was in a brothel in Salonika, nearly seventy years ago. I caught syphilis-lots of the girls had it-we called it Cupid’s Disease. My husband saved me, took me out, had it treated. That was years before penicillin, of course. Could it have caught up with me after all these years?’ There may be an immense latent period between the primary infection and the advent of neurosyphilis, especially if the primary infection has been suppressed, not eradicated. I had one patient, treated with Salvarsan by Ehrlich himself, who developed tabes dorsalis-one form of neurosyphilis- more than fifty years later. But I had never heard of an interval of seventy years-nor of a self-diagnosis of cerebral syphilis mooted so calmly and clearly. ‘That’s an amazing suggestion,’ I replied after some thought. ‘It would never have occurred to me- but perhaps you are right.’ She was right; the spinal fluid was positive, she did have neurosyphilis, it was indeed the spirochetes stimulating her ancient cerebral cortex. Now the question of treatment arose. But here another dilemma presented itself, propounded, with typical acuity, by Mrs K. herself. ‘I don’t know that I want it treated,’ she said. ‘I know it’s an illness, but it’s made me feel well. I’ve enjoyed it, I still enjoy it, I won’t deny it. It’s made me feel livelier, friskier, than I have in twenty years. It’s been fun. But I know when a good thing goes too far, and stops being good. I’ve had thoughts, I’ve had impulses, I won’t tell you, which are-well, embarrassing and silly. It was like being a little tiddly, a little tipsy, at first, but if it goes any further . . .’ She mimed a drooling, spastic dement. ‘I guessed I had Cupid’s, that’s why I came to you. I don’t want it to get worse, that would be awful; but I don’t want it cured-that would be just as bad. I wasn’t fully alive until the wrigglies got me. Do you think you could keep it just as it is?’ We thought for a while, and our course, mercifully, was clear. We have given her penicillin, which has killed the spirochetes, but can do nothing to reverse the cerebral changes, the disinhibitions, they have caused. And now Mrs K. has it both ways, enjoying a mild disinhibition, a release of thought and impulse, without any threat to her self-control or of further damage to her cortex. She hopes to live, thus reanimated, rejuvenated, to a hundred. ‘Funny thing,’ she says. ‘You’ve got to give it to Cupid.’

[@BethBurns68]

That was very interesting and I'm glad she could continue her rejuvenation for a while longer. :)

[@808bigisland]

Nice story!

[@Sgt-xw5lx]

Amazing story

[@prapanthebachelorette6803]

Glad she got treated and gain it both ways

[@RichardOlsen-k7i]

Insane isn't it?? How we react to just everything around us. Or bodies are so f-n awesome.

[@abd-animation-22]

I wonder what the people thought of the scientist who said that the infection can come back 15 years later Like how did he discover that and link it to syphilis

[@nikitakazakevic1928]

Well, there were some very unethical experiments.

[@mekkler]

@@nikitakazakevic1928 i.e. the United States government intentionally infected mainly African American males with it. Go ahead and say it, lest we forget.

[@tomlxyz]

I think it was known way before scientists got involved, specifically in regards to it being linked to prostitution

[@michaelmichaelagnew8503]

He took one for science lol.

[@michaellavery4899]

If you were a pupil in my science class, I would say that was a good point and a great question. However, if you were a pupil in my English class, I would reprimand you for your failure to use punctuation correctly. If I was a real teacher, I probably wouldn't be wasting my time, and yours, making crass comments on KZbin, so forget about it.

[@fbllflameengineer3511]

Yooo these episodes getting more dark I love it

[@joshuagerthoffer2321]

No shit.

[@breathnstop]

People are still suffering. I had a homecare patient 84 losing her mind. We cured her after she tested positive with massive doses of IM pcn. She was shocked about the diagnosis. " I only had one man my whole life... my husband". Turned out he was running around. A lot.

[@Michelle-ft6yt]

Had a neighbor who died with Syphilis tell-tell signs. I eventually worked at nursing facility she was placed in. Ms. Luella RIP

[@KS-yp1jl]

*telltale

[@midloran]

I'm sorry to hear that. Rest in peace, Ms. Luella

[@iklektikEye]

Why are you giving out her information? That's a HIPPA violation. RIP to her.

[@polishdoggo6371]

This video is the best promotion of being responsible with what you do with other people i have ever seen

[@chateaupig826]

Yep , I'll be demanding my intended partner takes a test to prove they don't have syphilis

[@BigBadJerryRogers]

This blood test should really be more widely available for everyone and free of course. It's just a simple finger stick blood test. They should be offering it at every CVS or rite aid.

[@mikejohn0088]

Stay home helps.

[@LimpBizkit999]

I just happened to stumble upon your channel. I am now hooked 🙂

[@marichristian1072]

Thank you. This is a disease that has highly specific periods of dormancy and eruption. If the infected patient is lucky, he or she will die of heart disease before the tertiary phase.

[@marcolozano4169]

Hopefully Syphilis will go away for ever! Very educational. Thank you Dark Science.

[@Edward1312]

These diseases never go away like cholera they are opportunist and await their next opportunity to infect as they persist in the natural environment. Only smallpox has been eradicated and even that disease still exists in medical laboratories.

[@z414141]

Go away?? It lives in humans so unless the population isn't wiped out then Syphilis won't be either.

[@krashd]

Sadly, with the rise of anti-vax quacks we can expect to see a resurgence of things like Syphilis.

[@soulsurfer7702]

It’s rare but syphilis can become resistant to penicillin due to people not finishing treatment. So even if one version of syphillis can go away forever another can pop up that is resistant.

[@NotMykl]

People are throwing fits over vaccinating for COVID and their kids for childhood diseases and there you are expecting them to go along with accepting meds to kill syphilis. There are to many dumbasses on the Earth to ever eradicate any disease.

[@zenwolf1046]

Right now in Alaska there is a quiet syphilis epidemic

[@sciencenerd7639]

Definitely horrifying! Love your channel, keep up the good work!

[@docjoe86]

Syphillis appears to have originated in the Americas and was likely brought to Europe during the Columbian exchange. The first confirmed outbreak was in 1495 in Naples Italy. There is some evidence of a similar disease in Europe before the columbian exchange, but it may have been a different disease with similar symptoms.

[@seanriopel3132]

Currently that is just an alternative hypothesis. It more likely existed in Europe long before that but it was not known about as the symptoms could have been attributed to more widely known diseases. That is why it is called The Great Imitator. Leprosy, for example, can cause horrible disfigurement just as syphilis does.

[@TheCrain]

I agree with this one. The other hypotheses need all sorts of on the money timing for them to be true. I mean, only AFTER they come back is when the outbreak starts?

[@seanriopel3132]

@@TheCrain what do you mean by "on the money timing" with reference to the other hypotheses?

[@TheCrain]

@@seanriopel3132 The Carbon dating on some skeletons where dated to right before the outbreak. That seems oddly specific.

[@seanriopel3132]

@@TheCrain They have similar evidence from a 9,000 year old skull in China.

[@astroboy90210]

I was diagnosed positive to Sy years back and I was totally devastated. I had chancre so I had an injection in my butt then took antibiotic for almost a month. That is a shameful disease and I hated myself because of it. I regularly take Sy test (VDRL) and it is in my blood permanently according to the doctor. I am worried coz I feel like I am starting to feel some later stage of it.

[@judyferguson3185]

When I got married in 1972, the couple was required to have blood taken to test for syphilis and gonorrhea. I guess that was one way to try to curb these diseases. But that was back then when you were required to be married to have sex🤣🤣🤣 so they held you hostage until you had submitted a sample and when it was ok, then you got your marriage license😄❤️🎉

[@madwhitehare3635]

Judy Ferguson……why the laughs? Staying faithful to one person seems to be a pretty good rule considering the subject of this video….. Certainly better than giving your body away to any Tom, Dick or Harriet.

[@karyannfontaine8757]

Yes, I recall that as well. Do they still require the testing?

[@pettytoni1955]

The tests were for STDs such as syphilis, and rubella (German Measles, which causes severe birth defects). Blacks and Latinos were also tested (and still are in New York) for Sickle cell anemia.

[@judyferguson3185]

Toni P when I got married in 1971 there were no vaccines for any kind of measles. Yes they were dangerous but the treatment was to keep kids home, in a dark room and ride it out. I am so happy that there are vaccines for most childhood illnesses.

[@pettytoni1955]

Judy Ferguson: While they've been using the combined Measles, Mumps & Rubella (MMR) vaccine for a number of years now, growing up in the 60's, my mom ensured we got the only vaccines available back then: separate measles and mumps vaccines, as well as the ones for small pox and polio. Yes, thank goodness for vaccines!

[@merwindor]

8:04 also appears to affect Windows activation.

[@ReaIHuman]

I'll never get sick of videos like this.

[@Clash19]

The only thing I don't understand is how syphilis remains dormant (my guess is to qietly spread?) and "decides" after 10-30 years to affect the blood vessels. Does anyone have an explaination as to how this happens? I can't find research about it

[@BigBadJerryRogers]

@@erathostenes-rq4mi that's all true. There's still lots of misconceptions about these diseases because education is so poor.

[@emgex]

im asking that myself, iv read lots about cases where people get diagnosed with symptomatic tertiary syph at age of 70+, and their last sexual encounter was at 40... Or people Catching it in early 20s and getting first serious symptoms at 50.. Maybe there are different Types of T. Pallidum that are less damaging, or maybe your own immune system keeps the Bac. at bay...

[@dragospahontu]

The single best KZbin channel in the world.

[@darkscienceyt]

Aw, thanks!

[@MaNkYmInX]

Absolutely fascinating. Just had to subscribe. Looking forward to more!👍

[@SQUAREHEADSAM1912]

Infamous composer of the time Scott Joplin the “King of Ragtime” died of dementia in 1917 caused by syphilis. He had likely caught syphilis in the 1880-90s, but didn’t show any fatal symptoms until 1913. In 1916/17 at the very end of his life, when his health was totally dead, he hand played 7 piano rolls that you could hear the decline of his mentally from syphilitic dementia. This is how bad his decline was. 1916 with mild dementia: kzbin.info/www/bejne/pn6kpX9to8RgqMU 1917 with severe dementia: kzbin.info/www/bejne/baeqkHyGnM-Cj9U

[@prapanthebachelorette6803]

Thanks

[@johnpayne7873]

Correction: oxygenated (from the lung) blood exits the heart through the aortic valve and into the aorta. Blood enters the left - or “systemic” ventricle (pumping chamber) - through the mitral valve.

[@maxxomega6599]

Also...excellent video. I had no idea Syphilis was so complicated.

[@karahershey]

It was a full on pandemic at one point in history

[@blackbird1543]

I couldn’t find a good asmr video so i fell asleep to this.

[@ReaIHuman]

This is something I'd love to learn about while in school.

[@chateaupig826]

Totally -Spot on , should be a must-see highschool classroom by classroom in the library 👍 Hoary pictures of boil clad sufferers should temper their passion

[@renato7184]

I did and was horrifyed of sex for years

[@KanyeTheGayFish69]

@@renato7184 as you should be

[@mr.d8214]

Back in 1973, I worked at the county fair for a week. A lady had open sore syphilis. An old man traveling with the carnys was having sex with her. The county health department was called and she was taken put in quarantine. She looked absolutely nasty. She had open, weeping, sores on her feet.

[@Strype13]

Fun fact: In the days before Penicillin, people of the more wealthy class (such as our founding fathers) used to wear those silly-looking powdered wigs in order to cover up the hair loss, as well as the funky smells that were attributed to Syphilis symptoms. That should give you something awkwardly neat to think about every time you happen to glance down at your [American] money from now on.

[@stevepalpatine2828]

Fun fact #2 - Al Capone died of syphilis in Alcatraz. He didn't have it when he got there, meaning Al Capone got buggered in Alcatraz

[@optimusdimegatron1297]

@@stevepalpatine2828 he had it before and died out of the prison.

[@MrIgottap]

@@stevepalpatine2828did you happen to miss the part about a 15-20 year dormancy period before the final stage kicks off?

[@angelofthedead1886]

The same thing with some European aristocrats as well.

[@michaelmichaelagnew8503]

@@stevepalpatine2828 He had it long before he got there. Since it takes decades to kill you.

[@rncine]

Lyme Disease symptoms are so eerily similar except they don’t get genital sores. Stages are very similar,too even to the bacteria entering the brain. Antibiotics also the cure.

[@zesty2023]

Lets all consciously give thanks to Alexander Fleming's work

[@hazymorning1823]

I love the amount of detail, enough to understand why and what is going on. I'm learning much!

[@petermcdougall1152]

Man i remember watching a video in school about stds. And let me tell you after watching it , you'll wanna wrap it every time.

[@davidtagauri2034]

Not all patients develop 3rd phase. Nietzsche definitely did, because he was definitely insane...

[@mikejohn0088]

He was born insane by the hand of his master.

[@sasa-ix9yd]

@Johnny Capybara Jr thats interesting because those people should be tested and studied to find out why the disease does not go further in them....what mechanism in their immune system is able to keep the bacteria at bay and prevent it from causig death? there are those with syphilis for decades who remain functional and appear healthy and they just get a chanker on their genitals every now and then and never break out in sores in orher parts of thr body...yet others break out in sores on their chest and back and face and even on the soles of the feet...anyway interesting research wpuld be to study cases of long term syphilis lasting 40 or 50 years to find out what it is that has allowed their body to keep the spitochete bacteria at managable levels...a similar phenomenon occurs in those with hiv...some people can carry hiv all their life and never die from it yet they can pass it on and someone who gets it from them is dead in 5 or 10 years without treatment

[@dianecleary1054]

There are no STD CLINICS IN MUSLIM COUNTRYS . I knew a doctor who had to state he was a dermatologist to enter saudi arabia to treat people . He often had old arabs with syphillus . Sad .

[@greghudson9717]

The picture of an "aneurysm" on a mans chest @ 7:23 appears to be incorrect. I've had an aortic aneurysm (10cm diameter), and it happens underneath the ribs / breastbone. The picture in this video appears to be a cyst (above the ribs, close to the skin), which is manifestly different from an aneurysm.

[@tomkudlan]

I swear to god I can look at dead bodies and blood all over the place for ages yet hearing about the horryfing diseases makes me sweat and anxious

[@TheFiown]

When I was 18 I got this illness from my boyriend who was a carrier without being affected by it. I found out by chance as it was leaving it's second stage. My boyfriend was in prison for fraud and to treat him, they changed prisons and he wasn't happy despite having given me and god knows who else this disease. Luckilly I had a good GP, the signs were small pink spots on the soles of my feet! Who checks their feet? I was treated for ten days with massive injections of penicillin into the muscle it wasn't pleasant at all. When he got out of prison he left me despite my having supported him during this time. Now I have a 'scar' in my blood and cannot donate blood and have to explain each time and for life.

[@JeremyS86]

The treatment is quite painful. Both sides of your hips or whatever, hard to walk afterwards

[@windsofmarchjourneyperrytr2823]

Stay single, my friends...

[@alexchong1933]

it is hard to see stories like yours happen. Modern medical treatments & practitioners should be enough to treat such cases in developed countries.

[@TheFiown]

@@JeremyS86 Yes they put a product anaesthesiant into the mix but one day I wasn't at home and had to go to a clinic in another town they didn't have the same product and afterwards I just could not walk and had to call a friend to take me home.

[@JeremyS86]

@@TheFiown yeah man, i needed 3 rounds, went 3 fridays. each time i couldnt walk lol

[@thangfahsavung9120]

Your pathophysiology is so understandable. I love it.

[@Travelin2Wit]

Interestingbut an unanswered question..... Are antibiotics effective at all three stages ? Understood they won't reverse damage but can the bug be killed at any stage and how did it affect the famous people mentioned at the start of the video ? thank you

[@quakeknight9680]

First video i watched since i subscribed

[@rynhart4174]

Topics added to things I never thought I’d care about: the progression of infections and how they find ways to thrive.

[@coppycatt]

I liked the old content, i like the new content. Great job right here. Keep going ❤️

[@moiraatkinson]

Interesting video. I’m probably being picky here, but penicillin isn’t used to treat syphilis. The antibiotic Doxycycline (a tricyclic antibiotic) is the treatment routinely given in fairly large doses. Apparently the thinking about how the disease developed is that it used to be a mild illness spread through skin contact in hot countries where very few clothes were worn. When it spread to colder climates and people wore clothes, the bacteria had to find a new way to survive and developed into a disease that was sexually transmitted.

[@dutyofcall7659]

First line treatment are penicillin antibiotics followed by tetracyclines in case of intolerances.

[@moiraatkinson]

@@dutyofcall7659 ok fair enough. I was prescribed Doxycycline and just noticed that it was used to treat syphilis from the information leaflet.

[@moiraatkinson]

@Erathostenes I don’t think anyone knows that, apart from being aware that bacteria do evolve over time.

[@dutyofcall7659]

@@moiraatkinson Syphilis don't become resistent to antibiotics which makes it so easy to treat. Other illnesses like tuberculosis on the other hand get resistent and are also hard to treat with several antibiotics at ones.

[@moiraatkinson]

@@dutyofcall7659 is that so? I didn’t know, but it does help in treating it.

[@Hootbass9791]

Informative. Thanks for the thorough quick video 👍

[@BK-wm1tg]

This is the most depressing little video and bunch of comments I’ve ever read my entire life, and ladies and gentlemen, I’m 82 years old

[@man_ish1234]

As a doctor, i highly appreciate this beautifully made detailed video yet with crisp information !

[@herberthall8082]

If you received penicillin during the 10 to 30-year dormant period, will that kill the dormant syphilis so that you never have the later third stage symptoms?

[@BigBadJerryRogers]

That appears to be the case. You can get a simple blood test at any time and it will show up.

[@episteme1289]

The aortic semilunar valve is not a passageway for blood to enter the heart; it is the first valve oxygenated blood passes through to leave the heart.

[@zbs8334]

Learned about this during my medical micro course. BACTERIA ARE TERRIFYING!

[@smalachit1571]

Informative and to the point. Very enjoyable.

[@karenstyles2623]

John list mom had syphilis and damaged her brain and central nervous system. John list murdered his entire family and went to another state to start over with a new family. He changed his name and his past caught up with him. He was arrested because he left his old family behind while his family deteriorating and rotting the old house. Happened in 1971.

[@Psychx_]

Niezsche would have never been so cool without his Neurosyphilis.

[@mirianakovachevic748]

It's a myth. Not truth.

[@SubtleStair]

@@mirianakovachevic748 I've read from Thus Spoke Zarathustra and it really does seem like something written by a neurosyphilitic madman would write.

[@mirianakovachevic748]

@@SubtleStair Researchers claim he developed dementia later in life as result of meningioma ( brain tumor which grows behind eye ), but that all happened after he wrote Zarathustra. He wasn't mad when he wrote everything of value.

[@babycarrotz32]

Heeey! I love your videos. I'd like to recommend a video, how the black death end or three examples of modern biological warfare/examples of medieval biological warfare.

[@LisaG442]

Interested to know if your still infectious during the dormant stage

[@adamvagenknecht]

Yes! Love your videos. Make more please 😅

[@doomyboi]

So it's possible to have Syphilis without knowing it, get antibiotics for something else entirely, and end up accidentally curing the disease in the process just because of how sensitive the pathogen is?

[@michaellavery4899]

Are you asking or stating something?

[@derek20la]

@@michaellavery4899 It's a question, and it's true. For example, doxycyxline is prescribed for many types of bacterial infections, but it is also effective against T. Pallidum that causes Syphilis.

[@michaellavery4899]

Thank's for clearing that up. The confusion arose as you started the comment with statements and ended with a question mark. The extraneous information in your reply was unnecessary but informative.

[@eliotasterforrest5026]

@@derek20la Janky! I've never had any STI tbh but I take doxycycline for acne during HRT

[@therideneverends1697]

its possible, but consideering how many diffrent classes of antibiotics are perscribed if you suspect an infection get screened, dont just assume the type of antibiotic you took is the correct one for a disease you where not formally diagnoised with