Maximise cosmetic absorption with penetration enhancers

[@DaytonaBleach]

Love the new look Belinda! Thanks for such an excellent video. I also love the combination of Montanov 68 and siligel.

[@theinstituteofpersonalcare6401]

Thanks for watching! Please contact us for the full formula, method and supplier details - FREE! [e-mail] Happy formulating!

[@everythingketomeals7960]

Finally Been waiting for this, LOVE IT. THANK YOU GUYS.

[@theinstituteofpersonalcare6401]

Thanks for watching! Please contact us for the full formula, method and supplier details - FREE! [e-mail] Happy formulating!

[@sollucetomnibus4469]

Love the content of the vid but I am here admiring and loving every bit of your hairdo.

[@theinstituteofpersonalcare6401]

Oh thank you!

[@sollucetomnibus4469]

@@theinstituteofpersonalcare6401, you most welcome!

[@satrihasim]

You are the best ! I learnt so much from all your educational videos. Thank you so much Berlinda

[@theinstituteofpersonalcare6401]

You are so welcome!

[@sahb8091]

I never thought I would be watching a channel like this, but here I am and understanding this stuff actually has the potential to meaningfully impact my quality of life. This is accessible, scientifically rigorous and wonderfully presented. Could someone please help answer where Magnesium fits into all of this and what might be a good way to maximise its penetration transdermally?

[@theinstituteofpersonalcare6401]

You will need to stabilise it effectively, as it is a strong electrolyte and can destabilise a lot of formulas. Please study our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ and also consider the evidence and claims you want to make; please study our Certificate in Cosmetic Labels and Claims: personalcarescience.com.au/BrandManagement/CertificateinCosmeticLabelsClaims-1979/

[@jaunbonaysmith]

Ms. Belinda Thank u for another great upload....❤ the New look U-Are-Glowing!❤❤❤

[@theinstituteofpersonalcare6401]

Thanks for watching! Please contact us for the full formula, method and supplier details - FREE! [e-mail] Happy formulating!

[@davidsotir4318]

Thanks for an informative video. Can you recommend any ultrasonic devices used to enhance penetration of topical skincare devices?

[@Candyprincess971]

Excellent content as usual thank you queen Belinda. 👌🏽

[@theinstituteofpersonalcare6401]

Thanks for watching! Please contact us for the full formula, method and supplier details - FREE! [e-mail] Happy formulating!

[@vhazeskincare9986]

Love your new look...and as usual your video is informative

[@theinstituteofpersonalcare6401]

Thanks for watching! Please contact us for the full formula, method and supplier details - FREE! [e-mail] Happy formulating!

[@sagechemicals9107]

Thanks a lot Belinda, the information you share is always amazing and well structured. Is propanediol an osmolyte, I tend to use it in place of propylene glycol?

[@theinstituteofpersonalcare6401]

Yes it is :) Learn to formulate with confidence with our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ or Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/

[@tanyawalker1673]

Excellent video, thank you so much Belinda.

[@theinstituteofpersonalcare6401]

Thanks for watching! :)

[@qsroyalesthetics5061]

Love your videos! So the penetrates helps with plant oils as well or just esthers? I’m formulating a body butter to help fade stretch marks, I want the benefits of the plant oils as deep into the layers of the epidermis as possible, so I would use a penetrating ingredient to make sure the effects get deeper into the epidermis??

[@theinstituteofpersonalcare6401]

Thanks for watching! The plant oils will just sit at the surface. It’s the active ingredients that may penetrate deeper - you will need to research the efficacy data of the actives to determine which will have the best results. Learn how to research materials properly for best results with our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ or Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/

[@malucamalucaa2346]

Excellent video. I was wondering which enhancer could you use for oil soluble active ingredients. Thanks a lot

[@theinstituteofpersonalcare6401]

Thanks for watching! Oil soluble substances tend to travel easier if their size is small; all substances will travel best in an amphiphilic base like an emulsion. Learn more about how to enhance delivery with our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ or Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/

[@nathalialedesma929]

linda i love all your great tips, can you send me the quantities and specifics of this formula ... my chemist is not as good

[@theinstituteofpersonalcare6401]

We’re happy to provide the full formula, ingredient, supplier, input and method details, please email us: [e-mail] and we can send you a link to access ALL our free formulas and reports. Happy formulating!

[@nathalialedesma929]

@@theinstituteofpersonalcare6401 thanks so muchhhh:)

[@christianbureau6732]

Great video again, thanks

[@theinstituteofpersonalcare6401]

Glad you enjoyed it

[@mariamamakouet1120]

Wwooww. Great teacher 🙏

[@KenzHair]

Hi! What course is this video featured in? I am looking into the Certificate courses and wondering if any cover skin anatomy?

[@theinstituteofpersonalcare6401]

Hi Mackenzie, This is taught in much more detail in both our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ and Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/ If you'd like more information, please feel free to email us at [e-mail] Happy Formulating!

[@roblim1767]

Hi Belinda, do you know any tips to deliver simple liposomal curcumin through the skin? I was thinking about oleic acid and safe electrical stimulation to open the pores. Do you have any idea about it? Thanks for the high quality content.

[@theinstituteofpersonalcare6401]

Thanks for watching! Liposomal delivery will assist with penetration but I don’t use any machines so can’t comment on that part.

[@AlfonsoCajiao]

Thanks for the video! Where can we get those spatulas?

[@theinstituteofpersonalcare6401]

Thanks for watching! Please contact us for the full formula, method and supplier details - FREE! [e-mail] Happy formulating!

[@iuliacarmen9989]

From where I could get in Europe argireline amplified for small businesses? Thank you

[@theinstituteofpersonalcare6401]

Try this page which lists hundreds of small suppliers all over the world: createcosmeticformulas.com/IngredientSuppliers/Suppliers-897/ Please also join our Facebook Group, Cosmetic Raw Materials for Small Brands: facebook.com/groups/1734896293290235// and post your request there, it is a group specifically to help small brands like yourself source materials like this in smaller quantities. Happy formulating!

[@reetabenny3908]

Hi there! Will isopropyl myriatate increase the penetration of niacinamide

[@shalomaideyan4579]

Hey, great video! Do you have any suggestions on cosmetic products or ingredients that will enhance and maximize a product's ability to penetrate the hair or can these enhancer be added to hair conditioners too?

[@theinstituteofpersonalcare6401]

Hi Shalom, Thanks for watching and for your interest! Please be sure to subscribe to never miss the latest releases. These enhancers weren’t studied on hair - in general if the cuticle is lifted you’ll get enhanced penetration. Damaged hair the cuticle is lifted! Also molecular weight matters - small molecular weight hydrolysed proteins, for example, can get into damaged hair cuticles for the best results. Happy Formulating!

[@yulaan7228]

Great video as usual! I wonder if there are lipid penetration enhancers that work better than others (eg for anhydrous systems)? I have often read that fatty acid esters such as Dermofeel Sensolv or the Cetiol range (Cetiol CC, Cetiol Sensoft, etc.) contribute to better penetration of the active ingredients while they remain on the surface of the skin like many fatty acids. But their molecular size tend to be smaller than fatty acids and triglycerides. I have never considered the polarity of lipid raw materials in my formulas but rather their other physical properties (molecular weights, viscosity, etc.) and the efficacy data provided by the suppliers. I have also often heard that non-polar lipids (especially those of mineral origin) do not penetrate the skin at all, unlike certain lipid raw materials of vegetable origin, and more particularly the more biomimetic ones such as phospholipids, phytosterols, etc. But maybe they aren't better penetration enhancers than non-polar ones? Anyway, is it even useful to consider the polarity of lipid raw materials? Do you have more information or scientific studies?

[@theinstituteofpersonalcare6401]

Learn all about this and more with our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ or Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/

[@Isiltarie]

what if your lipophilic actives dissolve only in ethanol? Can ethanol-dissolved actives be put in without disrupting liposomes?

[@theinstituteofpersonalcare6401]

Learn how to formulate with active ingredients, including how to stabilise them in your formulas and check quality/stability with our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ or Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/

[@reetabenny3908]

I already got your email of formulas. Can u tell the name of the product you made so that I can look it up.

[@patosa8228]

Thanks for this video. Pls can one use two different penetration enhancers.

[@izzuearfan2028]

Tq belinda.. Awesome!!

[@theinstituteofpersonalcare6401]

You're welcome!

[@matchmedicines8209]

and just a question, what is the best pH for these products according to skin pH?

[@theinstituteofpersonalcare6401]

Skin pH is 5.5; but you need to adjust your formulas to suit the pH requirements/biocompatibilities of the actives and preservatives used in the formula. So you need to consider the actives and adjust the pH to suit.

[@jasminadjuranovic695]

Hi, would like to know if Isosorbide dimethyl ether is also penetration enhancer? And is it as good as Isosorbide dimethyl? Thank you.

[@theinstituteofpersonalcare6401]

Learn how to formulate with active ingredients, including how to stabilise them in your formulas and check quality/stability with our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ or Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/

[@peptidejordn9845]

Thanks for this great and useful information, i have a question, may i use DMSO as penetration enhancer ? and is it safe to use on skin?

[@theinstituteofpersonalcare6401]

DMSO is prohibited in cosmetic products in the EU, so no.

[@micheles2815]

Is propanediol considered an osmolite ?

[@theinstituteofpersonalcare6401]

Yes it is. You can also learn how to formulate professionally and make these selections with confidence with our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ or Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/

[@nathalialedesma929]

what plants oil penetrate the dermal layer, it must be a high hdl right

[@theinstituteofpersonalcare6401]

Thanks for watching! Certain fatty acids from some plant oils have been found to have good penetration, but the impact this has for multi-ingredient personal care is unknown and limited research to prove or disprove this has been conducted. You will find this study interesting reading, but a lot more needs to be done before a definitive list can be provided, and please note it would also rely a lot on what else is in the formula, application, and it should also be remembered that it is not the whole oil that penetrates, and only certain fatty acid portions: www.ncbi.nlm.nih.gov/pmc/articles/PMC6151382/ In other words, more work needs to be done to determine this properly.

[@theholisticbeaute]

Are the enhancer good to use in natural or organic products?

[@theinstituteofpersonalcare6401]

The natural choices can be used, and help enhance activity - just check that your source is compliant with the natural or organic guidelines of whom you are certifying your products with. Happy formulating! :)

[@lillyj7730]

Thanks so much for this. Is propylene glycol a safe penetration enhancer?

[@theinstituteofpersonalcare6401]

Yes it is - despite the rubbish on the internet, propylene glycol is a perfectly safe material.

[@bluelavender7773]

Hi Belinda, would you be so kind to tell me if a product contains 10% propylen glycol is safe to be used on the face? Thank you so much.

[@riseandshine11]

@@theinstituteofpersonalcare6401 i just earnt my trust. A real chemist with real facts. Love it!

[@anithaprakash8898]

How much percent dimethyl isosorbide should be used in formula...please tell mam..

[@theinstituteofpersonalcare6401]

We’re happy to provide the full formula, ingredient, supplier, input and method details, please email us: [e-mail] and we can send you a link to access ALL our free formulas and reports. Happy formulating!

[@Rocky-ov1zf]

Hello, thank you for this video. Are there penetration enhancers that are not chemically based? Are there any plant based alternatives?

[@theinstituteofpersonalcare6401]

Use osmolytes like glycerin - all natural - and very effective to help with penetration to the mid-layer of the epidermis. Learn to formulate confidently with our Certificate in Advanced Cosmetic Science: personalcarescience.com.au/CosmeticScience/CertificateinAdvancedCosmeticScience-478/ or Diploma of Personal Care Formulation: personalcarescience.com.au/CosmeticScience/DiplomaofPersonalCareFormulation-479/

[@toyosiogunsori4452]

Propylene glycol will also do but they are not effective as Dmi, azone oil etc.

[@Rocky-ov1zf]

@@toyosiogunsori4452 Thank you for the recommendation!

[@Rocky-ov1zf]

​@@theinstituteofpersonalcare6401 Thank you!

[@toyosiogunsori4452]

@@Rocky-ov1zf for body butters and body oils use azone oil is more effective than DMI. Use Isopropyl myristate together with Azone oil they have a synergistic effect. Tell me how it goes sis.

[@amiraalmubarakmakeup05]

Curly hair ❤️❤️ another story

[@theinstituteofpersonalcare6401]

Thanks for watching! Please contact us for the full formula, method and supplier details - FREE! [e-mail] Happy formulating!

[@matchmedicines8209]

thanks a lot, same as always it was perfect

[@theinstituteofpersonalcare6401]

Thanks for watching! Please contact us for the full formula, method and supplier details - FREE! [e-mail] Happy formulating!