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[@jackarmstrong3364]

I have been a Prostate Cancer patient for over 3 years and following PCRI activities most of that time. I believe Dr Scholz is one of the smartest doctors in the cancer care field. Dr. Moyed is without a doubt the best interviewer of Prostate Cancer professionals in the nation. When you have both of them working together to bring us great information we are treated to a magnificent flow of timely brilliant information that only results when two men love and respect each other. Thank you guys.

[@Rockinrn]

Thank you Dr. Scholz for sharing all of your expertise. I was diagnosed with Gleason 10 in February of 2023. Being a retired RN I have been able to gain a deep intuitive understanding of the disease from your videos. I am fortunate to have an excellent team comprised of a medical oncologist, radiation oncologist and urologist. Because of your videos I’m able to ask the right questions and truly understand the treatment options they are proposing. Again thanks for the videos and keep them coming.

[@wendellrider1212]

Great questions and answers.

[@ricknowak4582]

. What are you going to do? What therapy. I am choosing prostatectomy over radiation. I don't think I could deal with the...ADT S#IT!! Ii obsessed the internet for info. I will take my chanches with the..... "BAG".

[@Rockinrn]

@@ricknowak4582 I have completed 9 weeks of radiation treatments (IMRT) which were not bad at all. I’m also on Lupron injections every 3 months which are not that bad for me either. Lastly I’m taking a second generation androgen blocker called Xtandi (Enzalutamide) which is 2 tablets a day. As of January 2024 my PSA is undetectable.

[@Faiselmoha]

@Rockinm Thank you for the comment. My father was diagnosed with locally advanced metastatic prostate cancer with PSA 42 and Gleason score 5+4 . I am not sure which treatment option should we go for. Some docs say Chemo, others say hormone therapy + Radio therapy, some say Immunotherapy, Spart pills. I am confused

[@Rockinrn]

@@Faiselmoha I had radiation therapy and hormone therapy at the same time. For me the side effects were pretty mild and my PSA has been undetectable for about 8 months and I feel pretty good. Really only your medical team can decide what is best. I hope you find the right treatment and everything works out for your father. Keep pushing and don’t give up.

[@kantibhaipatel8332]

I listen to Dr scholz multiple times and update . because I am a veterinarian and prostate cancer patient since 2 years and I am 74 years old and still working at Queens Animal Hospital as a veterinarian . When Dr Scholtz touched spirituality and could not remain silent. for some reason I listened so many videos about life , meditation and others and that made me completely out of stress of life and deaths too, before even I was diagnosed with prostate cancer, I was completely prepared for that. I believe in modern treatment. Because in life,we narrate hundreds of things,we don't have, but we have thousands of things that we have, for example life. I didn't ask for life and then life isn't mine and death is also not mine. So why should I worry of deaths. I am 74 years and loved life. Is not enough. supposed if I have been born 50 years before.This relieved me of any stress. Enough and nothing pending and no materialistic desire and peaceful only

[@BMT-by5ve]

Thank you Alex and Dr Schultz for sharing info and educating us. You provide excellent service to community.

[@roberthuff3122]

🎯 Key points for quick navigation: 00:00 *🛡️ Overview of Advanced Prostate Cancer* - Advanced prostate cancer overview, - Metastasis is key in defining advanced prostate cancer, - Treatment varies based on the cancer's location and metastasis. 03:28 *⚡ Treatment Approaches for Advanced Prostate Cancer* - Main treatments include hormone therapy, chemotherapy, and radiation, - PSMA PET scans have improved the treatment accuracy, allowing better targeting of metastatic sites. 09:49 *🩺 Role of Radiation in Prostate Cancer Treatment* - Radiation wasn't prioritized previously due to poor imaging, - Improved PSMA PET scans have enhanced the efficacy of radiation therapy, - Accurate scanning allows for precise targeting of metastatic cancer sites. 17:20 *💊 Hormone Therapy and Chemotherapy Insights* - Hormone therapy can be effective, especially in lymph node disease, - Combination of hormone therapy and other treatments enhances efficacy, - Chemotherapy is used as a part of advanced treatment strategies. 24:04 *🧬 Genetic Testing and Immunotherapy* - Genetic testing identifies mutations for potential parp inhibitor treatment, - Immunotherapy options like Provenge stimulate the immune system, - Genetic mutations guide treatment decisions, improving survival chances. 30:48 *🔄 Sequential vs. Combination Treatment Strategies* - Traditional sequential approach may limit long-term efficacy, - Combination therapy offers more potent early treatment, extending survival, - Patient case studies highlight the benefits of combination strategies. 37:02 *🌐 Current Research and Future Directions* - Studies show better outcomes with combination treatments even upfront, - Emerging research focuses on optimizing treatment combinations, - Triplet therapy shows promise for improving survival in newly diagnosed metastatic patients. 27:17 *🤖 Emerging Treatment Strategies for Metastatic Prostate Cancer* - Discussion on different treatment strategies depending on the type of metastatic disease, - Potential benefits of molecularly targeted therapy for patients with specific genetic mutations, - Exploring the prospects and implications of achieving complete remission with long-term treatment. 28:58 *🧪 New Advancements in Radiation Therapy* - Introduction of luticium-177 and its advantages over previous treatments, - Highlights on the versatility and side effects of newer radiation therapy options, - The potential role of testosterone re-administration therapy in treatment plans. 32:51 *🧬 The Role of Genetic Testing in Personalized Medicine* - Importance and potential of genetic testing in identifying new treatment pathways, - How genetic mutations might influence treatment decisions, - Discussing options beyond FDA-approved treatments through investigational trials. 36:08 *🌟 Future Directions in Prostate Cancer Treatment* - The promise of actinium and its current status in clinical trials, - Emphasis on early diagnosis and combination treatments to prevent metastasis, - Future research prospects driven by substantial funding and high prevalence. 39:12 *🩺 Bone Health Management in Prostate Cancer Patients* - Underlining the importance of bone density testing for patients on hormone therapy, - Discussion on strategies for prevention and management of osteoporosis, - Overview of both oral and injectable bone-protecting agents. 46:39 *💉 Immunotherapy and Vaccination Insights* - Evaluation of current status and limitations of CAR T-cell therapy, - Provenge's role and implications in the treatment landscape, - Considerations when combining Provenge with other treatments like Xtandi or Zytiga. 50:16 *💉 Immune Therapies and Oligometastatic Disease* - Discussion on the use and frequency of Keytruda (pembrolizumab) in patients depending on specific markers. - Use of Keytruda and radiation for oligometastatic sites and early-stage metastatic prostate cancers. - Concerns regarding measurement of outcomes and compassionate use by Merck Pharmaceuticals. 53:23 *🌟 Immune System Role in Cancer Control* - Importance of the immune system in containing small tumors and preventing infections. - Illustrations of immune system efficacy using Covid-19 vaccine examples, preventing severe cases in cancer patients. - Discussion on silent effectiveness of immune systems in preventing cancer metastasis for extended periods. 56:09 *🌍 Covid-19 and Cancer Patient Precautions* - Importance of cancer patients, especially those with prostate cancer, having Covid-19 vaccines and antiviral medications like Paxlovid while traveling. - Statistics on hospitalization rates for cancer patients with Covid-19 and benefits of preparedness. 58:00 *🧪 Evolving Perceptions of Chemotherapy* - Changes in perceptions due to lower toxicity and improved efficacy of modern chemotherapy drugs. - Usage of taxane-based chemotherapies such as Taxotere and Jevtana, and occasional use of carboplatin for resistant cases. - Use of indicators like PSA for evaluating chemotherapy effectiveness. 01:03:16 *🌈 Miraculous Outcomes in Prostate Cancer* - Increasing cases of patients surviving long-term after treatment for metastatic prostate cancer. - Synergistic effects of combined treatments leading to unexpected success stories. - Improvements in detection and treatment strategies contributing to better outcomes. 01:09:12 *🔍 Biomarkers and Advanced Cancer Screening* - Examination of markers like chromogranin A for castrate-resistant prostate cancer (CRPC) patients. - The utility of PET scans over blood markers in advanced cancer due to their specificity and ability to detect rare variants. - Exploration of different PET scan types for comprehensive detection of multi-clonal advanced prostate cancers. 01:11:15 *🙏 Importance of Faith in Medicine* - The speaker emphasizes the significance of faith and spirituality in personal and professional life. - Faith is considered important for maintaining steadiness and improving quality of life in patients. - There's a belief that life's difficulties motivate personal growth, with faith aiding in finding positivity. 01:14:14 *🎾 Light-Hearted Moments and Humor* - The segment transitions to a lighter note with a humorous gift exchange involving a tennis ball. - The tennis ball serves as an advertisement with a witty message about surgery preferences. - The interaction underscores camaraderie and humorous engagement in a professional setting. Made with HARPA AI

[@fullnoeleko]

Thanks a lot, Docteur Sholz, Docteur Moyad and Alex. So instructive, so valuable. It's allow me to have better comprehension, and in addition, I can now, ask my oncologist about wath it's possible for me here in Belgium. Thanks a lot

[@jessesanchez9893]

Awesome brother, im starting my fight with advanced P/Cancer and am trying to see if my change of diet and excercise and the keast surgery as possible..Im a very positive person with my faith in our Almighty father, so i know that im not alone and believe that faith and positivity is the vibe that i get from your the same..Ill yake any tips and advice from a friend and brither in Chris who has walked steps yhat ill be walking shortly..My daughter is a Junior in HS and my goal is to see her walk the graduation stage 🙏. God bless and you are in my prayers..

[@johngrimkowski598]

amen bro

[@kasiakasia742]

I hope you are better. Good luck with everything.

[@sandrawesterlund6566]

Thank you for all the education you share.

[@maverickat4544]

Thank you for such a comprehensive overview on metastatic PC. Living in South Africa access to this knowledge is pure gold. Now to convince my doctors based on this info....

[@robbujold7711]

Brilliant presentation. Both comprehensive and clear. Thank you!

[@edwardbertorelli7358]

Amazing amount of information and lucid detailed presentation .... thanks

[@donalddeacon8483]

Excellent!

[@johnnyjames7139]

I wish that I had gone to this doctor who really knows this subject.

[@en1chef54]

Excellent information from the you guys; but by now that what we have come to expect! Once again you have influenced me. I was diagnosed with advanced prostate cancer, a year and a half ago. PSA of 46 at the highest test. And after radiation plus Lupron shots! My PSA is 0.75 and continues to fall. I have not hit my PSA nadir. But, the good news is it continues to fall and we test it every 4 months, or 3 time a year! I am 13 months from my radiation treatments. And I been on Lupron shots for almost 18 months. But, I have decided to continue the Lupron shots for at least 24 months. To see if my PSA hit the magic number of < 0.1, thanks to the excellent information I get from these videos. I have used the information as wise counseling. As I fight the good fight against prostate cancer. PS, I have not been sick from the prostate cancer at all over the 18 months fight! And that’s what’s up!

[@Rockinrn]

I was diagnosed with Gleason 10 in all 12 cores and a PSA of 137. I was put on Lupron and started taking Xtandi prior to my IMRT treatments. I received 9 weeks of IMRT. My PSA dropped to less than 0.1 about half way through treatments. I am still on Lupron and have been taking Xtandi for the last 6 months. Hope my PSA stays at less than 0.1. In my opinion Xtandi is one of the prostate cancer miracle drugs.

[@en1chef54]

@@Rockinrn thanks for the information, keep the faith.

[@Rockinrn]

@@en1chef54 You as well.

[@Gipperboloid]

How you feel it after radiation? Thanks

[@Gipperboloid]

Stage 4 meet bone ? Thanks

[@FifiDiamond-e1d]

I came across your U tube video by accident, but just at the right time. My husband has just had his biopsy and waiting for the Dr. to relay the results. You give so much insight, i feel we can still do more education b 4 being rushed into surgery or treatment. They sent test results in My chart. B4 the dr has even looked. At it. Top hospital , but almost felt like a mill .

[@ThePCRI]

Hello, we can help you through our Helpline who can speak with you either by phone or email. Here is the link to contact them: pcri.org/helpline

[@perfectly22smith38]

Fantastic info. Thank you 🙏

[@ellenabella392]

Thanks alot much grateful

[@nickband2072]

More really good information , thank you so much for these videos. I was first diagnosed in 2009 at the age of 62 and thanks to the knowledge that I have gained from your videos I feel more optimistic now than I did then.

[@gulshani8331]

U have metastatic prostate cancer what your Gleason score?

[@Freedom24560]

Thank you for speaking on faith. Much respect.

[@georgefitzhugh6455]

I was diagnosed with prostate cancer/ bone Mets almost 2yrs ago. I am currently on Zytiga and Lupron with a fluctuating PSA number. I am working closely with my doctor and doing everything I can do to help myself. I am 65 now and played sports in my youth which lead to some knee issues and now I’m thinking about taking collagen to help but I just heard I should stay away from animal protein which is the best source of collagen comes from. So, I hear you but what would you recommend as a replacement? Thank you for sharing your knowledge, expertise, and experience. You have definitely given thought to my continued conversation with my doctor. Very helpful.

[@bobwright3438]

you wrote "from animal protein"; the "Farmers" are injecting/feeding these animals ( nor wild caught fish) that will aid the Prostate Cancer , I eat only S.M.A.S.H (Sardines, Mackerel , Anchovies, Salmon and Herring)include COD.From a comment of PCRI After being diagnosed with metastatic prostate cancer with a very grim prognosis ( Gleason 10 , PSA 587) i was put on hormone deprivation therapy and a keto diet to cut out "sugars" .My PSA would not get down below 211 . After seeing Dr. Scholtz 's earlier videos on avoiding animal foods i went on a strict whole plant based diet and a weight training regimen. 3 months later my PSA plummeted to 0.01. And has remained there for 3 years now! I am absolute living proof that a plant based diet has a massive impact on advanced prostate cancer survival. Thank you Doc Scholtz . So grateful i found this channel years ago!

[@ricknowak4582]

Animal protein right.?. Stay AWAY? RIGHT? Well,, I've been researching and many people are saying that the .... k e t o Diet is best for prostate cancer. I am totally confused now. Then I heard stay away from fruit. And some say eat blueberries strawberries et cetera. Only meat Diet will kill off the cancer. I have prostate cancer with a gleason seven. The doctors are shuffling to get my business. Like vultures I believe. Gosh I wonder if I am right. Seems like any treatment I take is just a lucky..."CRAP SHOOT"! A ....."ROLL-OF-THE-DICE"!!!! HA My gleason 7 is a um 3+4!! A diff look at the biopsy came back a ... 4+3=7 !!!!! WTF !?!?!?! TOTALLY CONFUSED!

[@ashleymorgan3516]

Thanks to Dr Sholz and Dr Moyad. I'm in South Africa under a Urologist. Are you aware of Oncologists here who are clued up with the latest triple combo treatment?

[@henryandrews2011]

Nice tie!

[@jaktao6044]

Great ties!

[@matshelanemashile8116]

Wonderful presentation! If one has been diagnosed with prostate cancer and is on treatment must one stop eating chicken?

[@EvensJean-zj6in]

In 2020 I had a biopsy that reavealed that I have early prostate cancer gleason 3+3, grade1. However my urologist never follow up and never refer me tto an oncologist. Now due to the negligence and carelessness of my urologist I have metastatic prostate cancer gleason 9 and stage 4. I have an oncologist who put me on hormonal therapy including lupron injection every 3 months, abiraterone and prednisolone. I am not sure if I have the right treatment at this time. Please let me know if I should have in addition radiation or somerhing else 1:15:4

[@terriblepainter7675]

With your diagnosis I would have followed up or asked what the follow up should be. Sorry to hear about your update. Your questions should be addressed with your oncologist or get another opinion.

[@stitcheruk1150]

Please continue to post your treatment and progress. I was recently diagnosed Gleason 9 with PSA at 310 - spread to bone skeleton.

[@EvensJean-zj6in]

@@stitcheruk1150 To my surprise the last PSA test taken is 0.2 I will not give up though my oncologist told me it's not a cure but will help me live longer. Good luck and seek help!

[@DCGreenZone]

Is Tulane's radio ligand going treatment to be approved anytime soon, and thank you for these stunning lectures.

[@perfectly22smith38]

Listening as typing. I just took a 3T MRI Scan. It said I have a Pirads 4/5. This is despite having a PSA of 1.5 up from 1.0 a little over a year ago. Over the past 2 years I have had slightly elevated ALP levels 130-140 (120 normal). My nodule size is .2 by .6 by .8. Smaller which is why it wasn’t a 5/5. On the positive side I had a exodx test of 4% which says it’s highly likely not to be aggressive. Question: should I get a PSMA pet scan (I live next door to UCLA) or possibly get a MPMri Prostate specific scan with and without contrast…and THEN get a biopsy if warranted…or just go straight to Biopsy. Tx!!!

[@gvet47]

I get very little help. Told I had prostste csncer and not treatable since in most lymph nodes. Given lupron shots saying it will maybe make me live longer. Day long sweats are a terrible way to live. Not told what will make me die and when.

[@georgeanneheaney7241]

Look into BAT. Your QOL will improve greatly.

[@peterdyes9724]

I had two metasteses oligo mets in my pelvis and backbone.....my prostate has recieved sbrt I had taxotare chemo and am on ADT......the bone mets are not showing on psma scan now....my psa is 0.01 can the areas where my bone mets are {presumably cancer is there but dormant] be radiated ..... the radiologist oncologist says say they cant see the tumours now to radiate.....can they radiate where the cancer was, the sclerotic tissue scarring?

[@m4rinos]

In the slide on Supportive Activities and Medication, behind “Vegan diet” is says “avoid multi vid, multi mineral” but it is never discussed. Could someone give me some info on that? 🙏🏼

[@michaelclennan8425]

Most of us non-doctors all believe all doctors are equal. Obviously some are more up to date in their education and attitudes.

[@n.c.b.8832]

Think I am learning just how uneducated my Oncologist is, sad for him and dangerous for me

[@skohaya]

Have Met both MDs due to family. They are so dedicated and aware of the many deep philosophies of prostate CA Treatment throughout the US. Get a consult from even out of state with Dr. Scholz. Very helpful! Praying for healing in journey!

[@DCGreenZone]

>>Undetectable levels of Prostate Specific Antigen (PSA) have been reported from the first patient with metastatic castrate-resistant prostate cancer (mCRPC) to ever receive two cycles of Clarity’s 67Cu-SAR-bisPSMA at the 8GBq dose level. PSA is a marker of tumour burden, clinical response to treatment and an indicator of the recurrence of disease for prostate cancer.

[@anilmehta6425]

ADT androgen deprivation .....n resistance to it both r causing fractures......long term side effects .......n treatment of mcrpc ...is very very difficult ....

[@Eclectic_RN]

Bone density check w/ Dexa or CT? Dexa picks up calcification of spinal ligaments giving erroneous data.......yes or no?

[@mauriceobure2308]

Hallow, kindly advise,I was diagnosed with prostrate cancer and radical prostectomy was done in Sept 2022, UpTo now no erection and still there is urine leakage, back ache, what's up still

[@PatB415]

How can you tell if the Lupron has 'run out of gas' when taken together with hormone or chemo treatment? The radiation spoken about for 8-10 metastatic areas (lymph nodes), is that Proton Radiation or ? My Husband's (age 82.5) prostate was radiated (40 treatments) in 2018 (with 5+4 Gleason in a few samples). Then he received Lupron with: Casodex, Abiratatone, Zytiga, Xtandi. Last week, he had #1 of Taxatere infusion (every 3 wks for 6 treatments) with anti-nausea & low dose steroid because of those few metastatic areas (largest 3/4") at the kidney level + a lower lung lesion that has been negligible (for >20 yrs) with no growth...until now (it's 1/2"). Prolia is on the horizon. Will follow up on the Neulasta, DEXA, Calcium & Vitamin D. Many Thanks for imparting this invaluable & timely info, for keeping us in the loop.

[@pamagee2011]

Dr Scholz often refers to “centers of excellence.” I’ve tried to find an authoritative organization that designates a center of excellence, but I haven’t had a lot of luck. Just what is a “center of excellence?” How do you find one? I think that Mayo, Johns Hopkins, and maybe Sloan Kettering might fit the bill, but there must be more. Thank you

[@espojespo5]

Yale Smilow in New Haven CT, Dana Farber in Boston, MD Anderson In Houston are all worth checking out!

[@mikeg9367]

Could you do a talk on High dose Melatonin and its effects on prostate cancer. I have been taking it for 4 months now and PSA is >0.01. I have stopped all ADT treatments due to the debilitating side effects I was diagnosed with stage 4 metastatic prostate cancer in June of 2022. No side effects from the Melatonin and now back to work full time. I was unable to work for more than a few hours a week under ADT and zitiga. The Zitiga gave serious liver issues and had to come off of it after 3 months. Dr. Switched me to Nubeca and the same thing happened to my liver. Not sure why he put me on the Nubeca as it offers no real OS with someone with metastatic cancer. If you just go to PUBMED and search Melatonin and Prostate cancer you will see over 200 peer reviewed papers on the cancer killing properties of Melatonin.

[@elijahghanbarnezad9909]

I had no idea, thanks for sharing that mate, what did your psa drop from

[@kkb651]

What dose are you taking? Thank you

[@Gipperboloid]

High dose Melatonin ??? 20 , 30 or 40 MG ??? Ones per day ? Just pils ? Answer please

[@terriblepainter7675]

@@Gipperboloidmaybe look up the studies on melatonin…

[@ivicadatkovic1173]

Hello Is it different between castret resistant prostat canser if it’s gleason 7 or gleason 10? Tnx

[@sagrammyfour]

DO YOU RECOMMEND PROSTOX BLOOD TEST? WHERE CAN YOU GET TESTE? HOW MUCH DOES IT COST?

[@ThePCRI]

For specific questions and information, please reach out to our Helpline here: pcri.org/helpline

[@DonnaDavidofCalhoun]

Has the combination of Orgovyx and Xtandi been associated with severe pancytopenia?

[@peterfardell9267]

Normal prostate tissue produces PSA. There are established limits to the PSA for non cancerous prostate tissue (roughly below 4 is probably "OK). So why is the PSA nadir value set at "below 0.1" after radiation/hormone therapy? Non cancerous prostate tissue could still produce PSA up to a value of 4 before getting worried.

[@xs2shankey]

How is zoladex as harmontherapy?

[@georgeanneheaney7241]

What about rBAT?

[@DCGreenZone]

>>Undetectable levels of Prostate Specific Antigen (PSA) have been reported from the first patient with metastatic castrate-resistant prostate cancer (mCRPC) to ever receive two cycles of Clarity’s 67Cu-SAR-bisPSMA at the 8GBq dose level. PSA is a marker of tumour burden, clinical response to treatment and an indicator of the recurrence of disease for prostate cancer.

[@kantibhaipatel8332]

very informative videos for us like prostate cancer patient= DR KANTI PATEL , 74 YEARS AND WORKING AS A VETERINARIAN AT QUEENS ANIMAL HOSPITAL WOODSIDE NY

[@georgeanneheaney7241]

What about BAT?

[@dusanjez2011]

We need much more science for metastatic cancer, hormone treatment should be abolished as soon as possible.

[@ga6589]

If ADT therapy works and side-effects are manageable, hormone treatments should be available to anyone who wants it. My husband was diagnosed stage 4 and is now in his third year of remission, with a negligible PSA. (He also initially received 26 rounds of radiation.)

[@georgeanneheaney7241]

You haven’t mentioned BAT .

[@rolandlickert2904]

Lots of various treatments like to know the side effects? I'm now 75 years old and wonder if treatment will be good for my Body. If I get 5 years out with no treatment I'm fine. I like to have a pleasant lifestyle and I do not expect to get 85 or 90. It can't be beneficial to your old body to get so many treatments!

[@ricknowak4582]

I agree a hundred percent brother. I am seventy. Gleason seven. Three doctors can't wait to either operate or radiate. Plus give me hormone treatments. I feel like saying... No. Take my. Chances with good healthy food. And I do exercise every day. Tennis. I am perfect weight. Haven't felt healthier in my whole life and they want to make me sick.

[@georgeanneheaney7241]

Using Propionate not Cypionate which has too long a 1/2 life.

[@jabster58]

Sounds like a nightmare and beyond..

[@ricknowak4582]

A pill for this a pill for that unbelievable. If your breasts get big we have a pill for that. Evan trouble urinating.We have a pill for that. And if that pill makes you sick we got another pill to fix the problem. I want to stay away from all this treatment and see if I could just change my diet ....DRAMATICALLY!!!! DUH

[@cherylconklin3288]

@ricknowak4582 there have been studies that are very promising by useing the controversial horse dewormer... Ivermection, Fenbenzadol, etc...worth looking into What do you have to loose ?!

[@cherylconklin3288]

Censored reply.... I will try again ! There are promising studies you can look it up .... By using the controversial horse dewormer.... what do you have loose. I would definitely try it, can't hurt !