What is Dissociation? (Plus: The Role Dissociation Plays in Treatments with Ketamine)

Watch my interview with Dr. John Krystal here: • All Things Ketamine, T... | Brought to you by Athletic Greens all-in-one nutritional supplement athleticgreens...., Helix Sleep premium mattresses helixsleep.com/tim, and Allform premium, modular furniture allform.com/tim
Show notes and resources: tim.blog/2022/...
Dr. John Krystal is the Robert L. McNeil, Jr., Professor of Translational Research; Professor of Psychiatry, Neuroscience, and Psychology; Chair of the Department of Psychiatry at Yale University; and Chief of Psychiatry and Behavioral Health at Yale-New Haven Hospital.
Dr. Krystal is a leading expert in the areas of alcoholism, post-traumatic stress disorder, schizophrenia, and depression. His work links psychopharmacology, neuroimaging, molecular genetics, and computational neuroscience to study the neurobiology and treatment of these disorders. He is best known for leading the discovery of the rapid antidepressant effects of ketamine in depressed patients.
He directs/co-directs the Yale Center for Clinical Investigation (CTSA), NIAAA Center for the Translational Neuroscience of Alcoholism, and Clinical Neuroscience Division of the National Center for PTSD (VA).
Dr. Krystal is a member of the U.S. National Academy of Medicine; co-director of the Neuroscience Forum of the U.S. National Academies of Sciences, Engineering, and Medicine; Fellow of the American Association for the Advancement of Science (AAAS); and editor of Biological Psychiatry, one of the most selective and highly cited journals in the field of psychiatric neuroscience.
He is the co-founder and Chief Scientific Advisor of Freedom Biosciences, a clinical-stage biotechnology platform developing next-generation ketamine and psychedelic therapeutics that recently emerged from stealth in August 2022.
ONE VERY IMPORTANT DISCLAIMER: I’m not a doctor, nor do I play one on the Internet. None of the content in this podcast constitutes medical advice or should be construed as a recommendation to use ketamine or psychedelics. There are psychological, physical, and sometimes legal risks with such usage. Please consult your doctor before considering anything we discuss in this episode.
Please enjoy!
About Tim Ferriss:
Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 800 million downloads and been selected for “Best of Apple Podcasts” three years running.
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[@MikeyFFA500]

Dissociation plagues my life and I don't know what to do about it.

[@JOY-ye2us]

Hi thank you Dr Krystal and Tim , I am going to speak with the head of a psychology practice tomorrow about ketamine treatment. I am in my 50’s and have major depressive disorder. I have tried every prescription available since I’ve been in my 20’s. I have never seen an improvement with any of them and the only thing I have felt from them speaking of SSRI’s and Others that increase serotonin, dopamine, ect have been negative side effects, such as nausea, shaking,twitching, weight gain, ect. You name it, I’ve tried it, along with clonepin for panic attacks. I don’t drink , smoke , I’m not an addict but I can not remember anything from my childhood and into my adulthood all I remember is being sad or distant to the world and other people or different. The only happy moment I can remember is seeing my daughter’s face when she was born. No one parents, teachers, doctors have ever noticed this yet tried to get me into treatment. I’m assuming it was due to my good grades and ability to blend in. I also have no other extreme emotions such as anger or any cluster B disorders. I am hoping for some help with this Doctor tomorrow. Would either of you have any suggestions as to how I can clearly communicate how I feel to him and obtain some sort of help so I can better improve the rest of my life in a positive way? Thank You Kindly, Joy, from Pa.

[@TheHumanRanger]

Have you looked into taking Niacin AKA vitamin B3, it helped a depressed friend of mine

[@JOY-ye2us]

That’s a good idea I never heard of taking Niacin but Dr Murad definitely recommends vitamin A. C. E for your skincare routine internally for youthful skin and that really does work for better skin, and a sense of well-being, thank you

[@mentalhealthfirstcoaching5248]

Hi Joy. I would recommend finding a coach or therapist who works with IFS. (Internal Family Systems) Your healing lives inside of your subconscious mind and inside your body. IFS can help you access what needs to be healed inside of you in order for you to unblock your life energies and live the life you deserve. When we are depressed, our life energies are blocked inside our bodies, hence our emotions and energy gets "depressed" inside the mind and body. I have seen many people heal from the exact predicament you are currently experiencing. You can do it. Be strong and be well.

[@thetshirtblog]

Joy you should definitely consult with someone about Ketamine. Mental health pros are generally good at interviewing new patients, and they will gently inquire about a lot of different aspects of your life and your inner world.

[@JOY-ye2us]

@@thetshirtblog thank you so much for your concern. I’d definitely love to see if if they these people can be found at

[@dustsky]

I wonder what's his view on dissociation vs detachment? Is there a point where these two intersect?

[@Jonas-I]

Please explore the topic of dissociation further

[@judepamment1106]

perfectly described in the first 5 mins 👌

[@sm7657]

I get severely dissociated when I am around hostile and abusive people and hostile environments . It makes my life unmanageable because I am constantly dissociating 24/7 , I am moving in and out of dissociation & flashbacks . I lived 4 decades like this - so my whole life . How do I fix this without drugs ?

[@finsterthecat]

What about people who are already dissociative in their every day life’s?

[@pauldesrochers418]

Is it ok to have katemine with benzos

[@anthonykent00]

I'm going to listen to the whole podcast, right now!

[@celiaortiz1499]

😅

[@ranevc]

Great vid, but what is ketamine?

[@TheHumanRanger]

It's a horse tranquilizer, also known on the street as Special K. Take with extreme caution, and under supervision of someone you TRUST!

[@Lord_of_Evil]

It is also an human anesthetic, but usually not the first line of choice.

[@TheHumanRanger]

@@priapulida Yes, every kind of drug has it's use in the right circumstance and the right dosage. Weed/Cannabis was known as a party/gateway drug and now I use it for medicine for my chronic pain. Oh and a side note people, if you get stuff off the street it is almost ALWAYS cut with stuff you probably don't want. Be safe, and be healthy people!

[@gsomethingsomething2658]

@@TheHumanRanger _"It's a horse tranquilizer,..."_ - It's true, but certainly misleading (annoyingly so) to just say it's a horse tranquilizer as it's also a human (and other animal) tranquilizer

[@TheHumanRanger]

Wow you are annoyed I tried to help someone, maybe YOU need some tranquilizer lol