Topical Estrogen is a YES. Here is why.

[@theredhedgewitch]

Deep dive please! Your content is always so educational. Thank you for what you do.

[@Jackie-is5kp]

Yes please and how to incorporate it with other actives like tret or if am Vit c thank u

[@denisebagwell1886]

Let’s dive!

[@carolinepeleg9811]

Oh yes please ...deep dive!!

[@mariasyperek9913]

Agreed, deep dive please!

[@robertporto1353]

Yes, please… Do the deep dive

[@tmm6884]

I used estradiol cream. Long before menopause. I ended up with inflammatory breast cancer stage 3b. I'm freakishly lucky that I survived. I'm cancer free for now. But, I'm also having a full hysterectomy next week because my estrogen is still too high despite being on a hormone blocker. My skin is gorgeous. But, my oncologist told me to stop the estradiol cream before I was fully diagnosed. She made that decision based on the fact that my type of cancer is often effected by estrogen and/or progesterone. How? If you have HER2+ breast cancer, estrogen and progesterone essentially feed the cancer making the cancer more aggressive and grow faster. She's the number 1 medical oncologist at Memorial Sloan Kettering Cancer Center, which is the number 1 treatment center for cancer. Literally. Just an FYI.

[@stephp7778]

Preach....because all these products are not necessary. I'm a stage 3 survivor....I understand the fear of what we use on our skin. You just never know what else these products do.

[@tmm6884]

@@stephp7778 Seriously, Amen!!! Now, I check every ingredient in my skin/hair care and food. Keep at it, my stage 3 survivor sister!

[@pipulas1]

thank you both for your comments. Both my mom and my mother inlaw had very serious problems (brain tumor and a stroke) caused (this said by the doctors curing them) by the estrogen pills or creams. Since then I do not trust any.

[@thisisspacepig]

I’m no doctor but I wonder if topical estogen would be beneficial as a skincare option specifically for post-menopausal women, where it might be potentially dangerous for pre-menopausal women. Or perhaps phrased differently, the risk due to increased topical estrogen is countered by the natural drop in estrogen from menopause, which makes it less risky for that demographic. Especially given that many women will take estrogen supplements during/post menopause to help with those symptoms, maybe this would be a two birds one stone thing.

[@madhu7983]

Yeah I think it's interesting that she phrased it as "estrogen deficiency." Pretty sure estrogen decline is natural as we age which would mean it's not a deficiency and just a natural change right?

[@gabrielachiodo9203]

Yes deep dive PLEASE! ❤

[@valerie.mccaffrey]

And include advice for women in their 30s who are interested!

[@freespiritchristina]

@@valerie.mccaffrey Yesss!! Peri-menopause can definitely begin in your 30s, typically late 30s, even though it usually happens around age 40-44! So that would be awesome… I’m nervous! Lol!

[@denisedoherty4909]

Yes. Please more info on this. I just turn 62 and in the last 6 months my skin has become dry to the point that moisturizer or evil coconut oil will penetrative my skin. I truly happened overbite and I'm not sure of what to do. Please help!

[@Analisaa.mariee]

Yes please, I'm in my early 30s and in surgically induced menopause. Would love to know more.

[@nn7397]

Please a deep dive! Also what if a woman is on hrt? Is it still needed? Will it be too much estrogen?

[@debbyd5729]

Deep dive! Menopause and all its effects on our bodies needs to be talked about more. I say this as someone who was 42 when she went through menopause. I had no friends going through the same thing as me.

[@b.h.7342]

Amen. Almost 41 and in late perimenopause now. Finding out constantly that so many negative body issues ive been having are part of it. The only symptoms you hear about much are hot flashes & night sweats. Those are brutal (for me) but this topic needs to be discussed more so we can understand it better and know it's so much more than that for some of us.

[@jcisking9622]

Mine is lasting over 10 years now 😢

[@Deadwrongallalong]

I’ve never heard of this being a thing before! It would be helpful to do a longer video

[@grammytammy3535]

Absolutely would love a deep dive on this! And please include about using it with other products like vitamin C, tretinoin, and other products. Thx so much!!

[@monejohn9973]

😅 You obviously know nothing about skin care.Because there's literally a million videos about everything that you wrote.And I do mean a million were tired of that same subject.She's actually talking about something different for once! Move t f onnnnnn

[@katek4275]

​@monejohn9973 so rude 😒 some people are new to things. They're just requesting that when she does discuss it, she talks about the interactions with other topicals, which a lot of videos don't address. The world needs more kindness and compassion, not what you just allowed to spew out of you. So unnecessary

[@grammytammy3535]

@@katek4275 Thx for the support! I agree... Kindness goes a long way. I appreciate your kind heart and hope you have a very blessed day! 👍🌼

[@badmamjamma]

So far at least 116 people liked your post, meaning they want the amswer too 😊 ​@@grammytammy3535

[@kathrynmashburn4465]

I would also be interested in interactions with other facial products!

[@db-gb5xi]

Yes, it would be good to get the difference between estradiol, estriol and even MEP. Not to mention, any counter indications of using any combination of them.

[@leksieb1]

It would also be helpful for her to discuss how to access these types of topical treatments.

[@db-gb5xi]

@@leksieb1 MEP comes in Emepelle and is a non-hormonal form and is available from Dermstore. The others are prescription. MyAlloy does estriol through their service.

[@ethernetgirl2001]

@@leksieb1through a doctor? you cant just buy hormones in most countries

[@nicolaxoxo1]

@@ethernetgirl2001yeah but now there’s all these internet Drs. I simply filled out a form and some Dr I never spoke with rubber stamped me getting a compounded estrogen cream to use on my face

[@RubGoddess]

Online​@@leksieb1

[@angelashaked8996]

Yes please. And could you also speak about history of breast cancer regarding estrogen cream?

[@felinegroovy]

After ovarian cancer I am on an aromatase inhibitor to rid my body of any remaining estrogen, as the tumour was estrogen sensitive. The effect on the skin is profound in terms of wrinkles and dryness, but I am guessing the creams she mentions would be potentially harmful for me.

[@alwkw3783]

Thanks for this question. I had no idea there may be a link.

[@Nerdy-By-Nature]

THIS.

[@tmm6884]

@@felinegroovy if your cancer is hormone receptive, yes, estradiol cream is not acceptable. I'm in that category.

[@tmm6884]

@@angelashaked8996 It could be a coincidence, but I used estradiol cream and was diagnosed with inflammatory breast cancer stage 3b in December of 2022. I'm still in treatment; taking oral chemotherapy and scheduled for an oophorectomy very soon. My cancer is hormone receptive so I can't even eat/take soy or animal collagen products. It's tough. If I could do it again, I would not touch any HRT anything. And, I'm a vain girl.

[@butterpopcorn5678]

Yes, deep dive! And a realistic pros and cons pls!

[@angora6881]

I think we all agree that we wish for a longer video on this subject

[@EvelynCastro-Lake]

I’d love to hear more about this. I’m 57, and have definitely noticed a change in my skin.

[@SamarPrakash-h8p]

Yes please do deep dive, I was thinking the same as to why we can’t use topical estrogen on face as anti aging. I am so happy to know it’s a thing and love to hear from a board certified doctor about use of estrogen topically

[@anniesimone]

It's not talked about probably due to putting estrogen on your skin (anywhere) it gets absorbed by your body, and that could potentially do more bad than good for some (hormone cancer or other conditions with hormones involved)

[@theresatomasello1843]

Yes! I would love more information and would like to know if it might be helpful for those of us over 65 years old.

[@analozada9475]

Yes!!! Deep dive, please! Mature women deserve to be informed and need solutions too. Thank you!

[@psyche8187]

Yes deep dive! Especially regarding research related to cancer and other risks.

[@SpeakTruthBeKind]

I have been in menopause for over 10 years and noticed the most skin change when I was mid-60s. Especially the décolletage area.

[@cedmunds2865]

Yes, please. More details about topical estrogen.

[@melanies828]

DEEP DIVE please! I had a total hysterectomy the year I turned 50 and salvaged one ovary. Turning 52 next month 😊 Life in many aspects has changed and I am open to all of your beauty and knowledge expertise. Appreciate your energy, transparency and enthusiasm.

[@MollyFossett]

Yes, Please...and let us know all we need about getting a prescription.

[@user99282]

@@JennyLouRN you don’t need to be a snotty little B to people!! Maybe, some people don’t go to the doctor every other week like you! Kindness goes a long way! Maybe try it for once.

[@QuickSilverHair]

Crepe skin is estrogen deficient. It’s crazy how quick it happens. I’m so glad you are speaking out…a little louder for those in the back. ❤❤

[@jilltaylor8252]

More info and products please

[@Mazzaaaaman]

It's HRT cream you get on prescription from your doctor. You rub it in your face instead of arm or thigh.

[@pjweaver6551]

@@Mazzaaaaman. Thanks for sharing this info. 😊

[@fitnessworksnc]

Yes! Please do a deep dive! Tell us about how it affects the skin and also if it gets systemic and causes any problems elsewhere in the body.

[@mdml0]

I've deep dove on this already and the thing is once you start on topical estradiol you're essentially starting on HRT. There's a certain target estradiol blood level range you want but not too much so this includes blood testing. And if you're postmenopausal with a uterus, then you're going to want to start taking progesterone pills to offset estradiol otherwise you start seeing side effects like bleeding and breast tenderness etc. Consult with an Ob-gyn trained in HRT for this.

[@denisemcdonald829]

I am glad to see at least one other person sounding a warning bell other than me. This doctor is a dermatologist, not a gynecologist or oncologist. I feel like this video is a bit irresponsible. People will watch this and start slathering it all over their face, neck and chest without understanding that the estrogen is absorbed through their skin. Anyone with a history of breast or gynecological cancers, or has risk factors (mother, sisters, grandmothers) who had breast or gynecological cancers need to be especially careful.

[@GloBurnett]

I would love to learn more

[@memorydandaroy1618]

Yep I have noticed a huge difference But mom was estrogen positive for breast cancer And I’m not taking ANY chances W hormones I’ll have to just deal with

[@Мира-м6н]

You might want to explore estriol as an option

[@EadsB7002]

same...my grandmother was with her breast cancer and my mom had pre-cancerous lesions in her uterus/cervix. not taking any chances with synthetic hormones,

[@tarapeters9493]

Yes please do a deep dive!

[@bfreeume]

Please deep dive. Thank You! I’m so exhausted. I’m 62, 8 years post menopause and finally getting info that makes sense from wise Women like you. Between too much stress and no more estrogen I’m wiped out. I swear it does happen overnight. Had I had the info I’ve learned of late in my mid 40’s life would definitely be different now. Perimenopause / Menopause needs to be understood by all Health Care Providers.

[@rhondalane4001]

Yes please talk some more about this! I am 63 and I don't use hormone therapy and am post menopause. Could I still try this and get some good results ? Thanks for your great videos! So informative!

[@Judy-jt4ow]

HRT user here. And it has been an absolute game changer. I recently started using estrogen on my face I don’t think long enough yet to notice an immediate change. But overall, just being on HRT itself has made a huge difference in my skin in addition to how I’m just feeling in general. I’m feeling normal again.

[@squirrelboss7067]

Same, same! 🥹

[@slinkywhippet]

As a perimenopausal woman whose skin has changed so much I would love to get a deep dive on it all. I'm at a point where I'm considering hrt & so this would be really helpful. ❤

[@sweetpeace5]

Do it! Life-changing/life GIVING❤

[@pjweaver6551]

@@sweetpeace5 hrt - interested and talked to my gyn- she was not encouraging. Please share or share a source for me to watch/learn about? TNX!!😊

[@juliehamamura-bz4yu]

Yes please talk more about topical estrogen for your skin!

[@margaretk9351]

Yes! Please tell us more! I haven't heard about cosmetic estrogen! Wow!

[@chiaralistica]

I'd really like to hear more about this, please include if and how absorption through the skin will affect the rest of the body. Thank you!

[@ourcozycorner8517]

More info please! So curious. What are the risks?

[@cate499]

No risks. It isn’t strong enough to be systemic.

[@4Renee9]

More about topical estrogen please!

[@AlisonIvy]

Yes Please dive deep, Doc! And please answer if it’s okay to use topical if you’re using an estradiol patch. Thank you!! Btw, LOVE Prequel! Just got my second delivery today!

[@cristinaahumada1111]

Yes! I have the same question.

[@jenniferpetty5238]

I use it. It’s helped with my red cheeks and my skin moisture is definitely improved. I use the estradiol patch and take the oral progesterone. Just turned 47 and haven’t had a period in over 4 months. I have the estrace 0.1 estradiol vaginal cream and use it on my problem areas about 3x a week. It’s also improved the look of upper lip lines.

[@jenniferpetty5238]

I heard a doctor say that the dose is very negligible to increase systemic estrogen levels.

[@AlisonIvy]

@@jenniferpetty5238 thank you!!!

[@pjweaver6551]

@@jenniferpetty5238 wait. You use the vaginal cream on your pblm areas like dry skin/wrinkles on your face?! That sounds brilliant. I think?

[@nancycy9039]

Yes to deep dive. I’m 75 and have just restarted estradiol topical cream - I think I need a higher dose. Please include dosage topic and how to combine topical for face with bio identical cream on inner arm for systemic dosing. TIA!

[@ssa2572]

Please give us more menopause HRT advice. Still in the UK women are being ignored about their symptoms

[@Himmiefan]

Your hormone levels change naturally for a reason. Focus on your diet and exercise. Taking hormones is not the answer.

[@jsuefnp]

Would love a deep dive and would love info on how topical estrogen would help differently from oral estrogen. As an NP, I once had an 86 year old patient who had the skin and hair of a 60 year old at worst! I asked her secret and she said she had a hysterectomy at age 28 and had been on high dose estrogen since. Even though she got out in the sun a lot, her skin was beautiful, and at that point, she had never had a bone fracture! I’d like your thoughts on if one would be more effective than the other or if topical would be best because of local and systemic effects. Thanks!

[@aky5701]

Deep dive please! And could you talk specifically about whether this is ok for those of us with rosacea

[@JennyLouRN]

YES!! Topical estrogen DOES help a lot!

[@badmamjamma]

Applied to the face? (Or the typical application sites like inner arm, etc.)

[@jdreis]

please do a deep dive? I think a lot of us feel lost on this topic.

[@juliamills3410]

I was diagnosed with breast cancer at age 40, estrogen and progesterone positive and I am just thankful to be alive! Would be great to hear a deep dive from oncologists and how they view these products for those of us who have had cancer

[@jenniferkenner1290]

Yes please do a deep dive including if it’s safe for breast cancer survivors. Mine was invasive and estrogen positive or whatever the term is. That said, I’d love to stop this rapid aging! I’m 61 and looked so much better just a few years sho

[@denisemcdonald829]

Please be careful. This should be discussed with your gynecologist and/or oncologist.

[@debfamilia8528]

I just use a lentil pea size estradiol cream on the episiotomy scar and vag opening so sex doesn't hurt as much. What ever is left on my finger I use on the clitoris to promote desire. What ever is left after that, I wipe on my lips which keeps them plump. I try to remember daily but at least do once a week. Obgyn said my privates were estrogen starved a long time ago but my blood levels say it's fine

[@heathergasol569]

Deep dive please! Thank you Dr. Ellis. I also want you to know Prequel Gleanser is my favorite cleanser of all-time! I thought I had my all-time favorite until I tried Prequel Gleanser! Oh my goodness! This cleanser makes me look forward to actually washing my face which was never the case before! It feels good on your face & as a person who has extremely sensitive skin with redness because of skin sensitivity not rosacea I appreciate NO FRAGRANCE!!!! I also appreciate that it’s NOT DRYING! I love it! Thank you for the large size also. I purchased (3) bottles at once. I use Gleanser all over my body.👏👏👏👏👏👏👏

[@greenlean8890]

Please do a deep dive! Can you please talk about if this could be beneficial for women to try this before perimenopause? I’m 35 and wondering if this could be good to help establish collagen stores leading into perimenopause. I’ve only heard it talked about 50-60s women doing this who are already in menopause.

[@DrElizA10]

Deep dive, and please discuss any increase in risk for estrogen sensitive breast cancer.

[@alenetimberlake7148]

Yes

[@VanessaSchwegman]

Yes! Please also include any risks for those with genetic blood clotting conditions. I assume absorption isn’t systemic, but some of us need to be more careful than others.

[@escobc4]

Yes please. Especially interested if it could trigger melasma in those without a history of melasma, but of hyper pigmentation.

[@amenahal-najjar9268]

Yes plz make a long form video on this! Would love to know the science and the pros and cons

[@dinewman4749]

Yes, deep dive please! I'm in my mid 50s and love to learn about ways to keep my skin as youthful as possible!

[@mrs.p5756]

Yes, PLEASE do a deep dive on topical estrogen!!!❤ I'm post menopausal and eczema just came out of nowhere! Especially during the summer months. I'm tired of the dry, itchy and patchy skin. My skin has never been like this!

[@KimZorich]

Love your information and education. More info on estrogen would be great.

[@valerie-nk9th]

Yes, deep dive please! With some education on how/ if topical estrogen might cause melasma, and what to do to avoid that while still getting the benefits.

[@colleencc7]

YES TELL US MORE ASAP. I’m a medical professional and I’m that magical age and they don’t want to talk about this (at least where I am) but obviously I’ve heard about it and I’m starting to see some of the changes that I’m not too happy with and they gave me topical Estrogen as a general supplement but TELL ME ABOUT THE FACE

[@lindakirkpatrick3416]

Deep dive, yes please. I agree your content is very educational. I too thank you. I have been using estradiol cream on my face and neck for a week so too early for positive results and I don't really know how to use it. The cream is thick so I mix it with a little oil free moisturizer. My GP prescribed it for me; neither one of us know the way to use it on the face. My Dr let me have it because skin aplication won't allow it to pass into the bloodstream.

[@marydavidson4816]

I’d love the long deep dive!

[@rachelcampbell8541]

I'm approaching 61 with breast cancer in my family. So, yes, my skin is hopelessly thin and dry and no, I'm not taking hormones. If you feature topical estrogen please advise regarding cancer and other risks.❤

[@arincrawford8800]

Yes please. Deep dive. And products

[@carlawalker7814]

yes!!!! please deep. dive and let us know exact products!! that's what we NEED!

[@e.beauchamp]

Yes please a deep dive!!

[@shellc7747]

I’m a 50 yr old woman & Topical estrogen broke me out. Not sure if other women have had this happen.

[@q5130]

Yes, more info please!

[@karenwright5168]

Yesssss deep dive. I’m 61 and yessss skin on my entire body but yes face is way more textured etc. I’m using retin an and Vit C and exfoliating too but still having these issues!!

[@suzannesteele1275]

Yes Deep dive, please! 😊

[@elainec5333]

A thorough pros and cons on it would be great with dosage, formulation and type 411

[@Sky10811]

which dosage for face and how to combine with tretinoin

[@shannoncagle8991]

Yes please. I would like to know more! Btw I’m 54 & I’ve learned more from you than a lifetime of going to my Derm.

[@theresalaviolette5849]

Yes a deep dive please. I know nothing about this topic.

[@jillc720]

My pharmacist says there is a strength particularly designed for facial skin and that I can’t use my prescription for “other” areas. My other prescription was a standard dose of Estradiol .01%. Please keep doing the deep dive on this. I have no family history of breast cancer.

[@lilelly16]

I would love to know more about this

[@loranneagu2001]

Yes deep dive!! Talk about application, when, where, and how to apply!! Dose?

[@cynthiagalvez6219]

Yes please deep dive. And do I ask my dermatologist or gynecologist for the script?

[@ChocolateBabe_]

Please do a deep dive into how it works? I thought about starting it years ago but was told it could cause breast cancer

[@sarahorange5031]

Deep dive please!😊

[@dermnp1603]

Yes please take a deep dive on topical estrogen. What ingredients? How to get it? Available at commercial pharmacies? Compounding pharmacies? Alloy app? Use ? Alternate with tretinoin?

[@JennyLouRN]

Let’s talk about the reasons why doctors don’t talk about it: #1 Hormones are not covered by insurance #2 It is difficult to prove you need hormone replacement. Even with lab tests, show a *demonstrable* health need. Saying “I look and feel older” does not work. #3 Previous (flawed) research that showed risks of stroke or cancer. #3 Creams are made for vaginal dryness, not the face, so scrips have to be off label.

[@suzannesutton5636]

Try different doctors till u find one. Ask women’s International pharmacy who prescribes to them

[@jodieclark4518]

Would love to know more about how topical estrogen works !

[@lindaparadis7154]

More information please

[@nicolegraham8813]

in 2020, was diagnosed with an estrogen positive breast cancer…at 32…while breastfeeding …& no family history. currently in a medical menopause to suppress my bodies estrogen. I wouldn’t consider it, for obvious reasons - but offer my lil story for a deep dive with consideration on hormone ‘levels’

[@hg-tm6gn]

I love this! Yes please!

[@karenhammer4015]

Yes please! And recommendations for a topical estrogen cream!

[@kzvegansuperstar]

Deep dive please!

[@londamaher920]

Yes, I would love to hear more on the benefits of topical estrogen! I’ve begun splitting my dosage a little so I can have some for my daily routine for my face and have noticed a big difference.

[@deann3621]

Yes to a deep dive please!!!

[@tamiiagrisham6353]

Thank you for all of your hard work to bring us helpful content. I would love to learn more about topical estrogen. May GOD forever bless you. I appreciate you tremendously!! Thank you.❤

[@safa1012]

Would love to see a deep dive on how to use this. Dose, how to apply, when to apply, safety etc

[@1slandgirlcaribbean304]

Dr. Sam, as a post menopausal woman, in her mid 50's, I'd love to hear more about topical estrogen. I've never heard about putting it on your skin. Please share away.

[@marybethcoonrod9424]

Yes, deep dive!

[@kerrylou3]

Yes, I have wondered this myself! If it can rejuvenate the tissue of the vulva and vagina why not the face?

[@kendallstark4302]

Deep dive FTW!!!!

[@ginaonyemaechi]

Please do a deep dive! ❤ Can you also do a detailed video on the benefits of topical oestrogen for beauty purposes? 🤔 😉

[@valerielowe8637]

I use a drop of my Divigel (estradiol) with my vitamin C serum every morning. I shared this with my OBGYN , and she remarked that she might change her h.R.T regimen from the patch so she can do this too.

[@amyswygert4532]

YES! Post-menopausal woman here. Would LOVE a deep dive.

[@naxp42]

Yes please! I'm very interested in either topical or oral estradiol when I'm peri menopausal and would love to learn more!!!!

[@hoovergrant]

Yes, I would love a long form video discussing how to use 1% estradiol cream on the face and neck. I’m post menopausal.

[@sarahgardner1668]

Yes, we need to know deep dive how to tell if it’s safe after menopause. How much etc.

[@MyCleverHandle]

It didnt help my facial skin - I got only increased rosacea. But what it did for my bladder control when applied every other night on and inside my lady parts is amazing!

[@Pubslife]

You will have to pry my tube of cream out of my cold dead hands😂

[@rachaelgraceblack]

Yes yes yes! Please deep dive! I’m just being hit super hard by peri-menopause and it’s driving me craaaaazy! Please talk about more dermatological and trichological peri symptoms!!! Thanks for all the content, you’re great!

[@AwkwardAdrian504]

I did topical estrogen for my anti aging routine - I’m 42 - it should be ok- but it WAS NOT AND I WANT TO WARN LADIES- I used a very mild formula and it caused me (after a few weeks of use ) to have a month long period - there were these giant blood clots coming out of me - the pain was so intense I could barely walk - I’m not a doctor so I sincerely thought I was dying . Got off the topical estrogen - no problems since

[@aracelirodriguez9932]

Yes please . Let’s talk more about this . I’m 63 , I missed the boat of HRT ,,, but I totally believe it that topical estrogen would be great for my skin . I already use the Estradiol vaginal cream . Is this the same thing ? And how do I combine it with my other creams , like Retin A . It would probably go on first right ? Thank you