Trichoepithelioma 101

See these videos for more about adnexal tumors:
Skin Adnexal Tumors - Dermatopathology Unknown Cases: kikoxp.com/posts/3824
Skin Adnexal Tumors: Dermpath Board Review: kikoxp.com/posts/2767
This is an excerpt from a virtual lecture that I delivered via the Zoom app to the dermatology and pathology residency programs at McGill University in Montreal, Quebec, Canada on March 26, 2020.
Link to all of the digital slides on PathPresenter.net:
pathpresenter.net/#/public/pr...
A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
For additional information on this topic, see my Dermatopathology survival guide textbook:
www.innovativesciencepress.co...
Also check out these papers from the literature:
- Fulton E, Kaley JR, Gardner JM. Skin Adnexal Tumors in Plain Language: A Practical Approach for the General Surgical Pathologist. Free PDF: www.archivesofpathology.org/d...
- Jedrych J, Leffell D, McNiff JM. Desmoplastic trichoepithelioma with perineural involvement: a series of seven cases. www.ncbi.nlm.nih.gov/pubmed/2...
- LN Clark, HR Elwood, EE Uhlenhake, BR Smoller, SC Shalin, JM Gardner. Nuclear factor XIIIa staining (clone AC-1A1 mouse monoclonal) is a highly sensitive marker of sebaceous differentiation in normal and neoplastic sebocytes. www.ncbi.nlm.nih.gov/pubmed/2...
- EE Uhlenhake, LN Clark, BR Smoller, SC Shalin, JM Gardner. Nuclear factor XIIIa staining (clone AC-1A1 mouse monoclonal) is a sensitive and specific marker to discriminate sebaceous proliferations from other cutaneous clear cell neoplasms.
www.ncbi.nlm.nih.gov/pubmed/2...
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
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Facebook: / jmgardnermd

[@JMGardnerMD]

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

[@Human_person.]

Very interesting! I was diagnosed with Trichoepithelioma in 2016. I have this all over my face! Trying to continue to learn about this!

[@JMGardnerMD]

I’m sorry you are dealing with this. Does anyone else in your family have multiple trichoepitheliomas? This often happens as part of a syndrome as you may already know. The good news is that they are benign but I realize they may be cosmetically very frustrating for many patients. Best wishes to you.

[@vanessabarros35]

I wish one day to watch your class! You are a legend!!!

[@erfansadaf]

Really informative. Thank you sir. You are a legend.

[@umarfarooqkhan8208]

Very nice cases increases our insight into dermpath

[@rajanchopra2193]

That's brilliant talk on this entity; many thanks Dr Gardner. You have touched upon this not so uncommon difficulty of very small punch biopsies from nose eyelids and ears for basaloid lesions; wherein one may not be confident of the significance of CK20; do you study 5 levels of CK20; related problem is the possibility of infunfibulocystic BCC. Can you please share your approach to this condition.

[@scratchgolfermd]

Yes. Please compare and contrast.

[@dibyanshusekharmohapatra9929]

Immensely informative. Thank you sir.

[@rabiaumer8759]

You are stating that in trichoepithelioma no clefting is seen and is evident by the slide you are showing.However, as a dermatology trainee I would like to point out that in Rooks it is stated that "the stroma in trichoepithelioma is distinctive in that it contains clefts"

[@dr.tarunroy6532]

This is extremely informative and helpful to me. Recently I reported one basaloid appearing dermal tumour with hair follicular differentiation. I shall be interested to know from you about the histogenesis of these tumors towards different morphological lineages. Thank you.

[@JMGardnerMD]

Thanks! Here’s another video about basaloid differential diagnosis: kikoxp.com/posts/6348. And I have other videos and digital slides of specific follicular tumor entities listed here: A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

[@TamNguyen-te1tk]

Thank you so much......

[@loransmokthina6352]

Hello, was also diagnosed with trichoepitelioma, how is this removed?