Tuberculosis: Humanity's Deadliest Foe

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Source/Further reading:
General facts on TB:
www.cdc.gov/tb/default.htm
www.msf.org/how-tb-kills
www.who.int/health-topics/tub...
History of Tuberculosis:
www.cdc.gov/tb/worldtbday/his...)
www.tbonline.info/posts/2017/...
tbfacts.org/history-tb/
wwwnc.cdc.gov/eid/article/24/...
www.thelancet.com/pdfs/journa...
WHO report: apps.who.int/iris/bitstream/h...
Medical Journal articles on co-morbidities and mycobacterial transmission: erj.ersjournals.com/content/4... bmcinfectdis.biomedcentral.co... www.ncbi.nlm.nih.gov/pmc/arti...
Robert Koch and the discovery of the Tubercle Bacillus: www.cdc.gov/mmwr/preview/mmwr... www.ncbi.nlm.nih.gov/pmc/arti...
Kathryn Lougheed, Catching Breath: The Making and Unmaking of Tuberculosis: www.amazon.com/Catching-Breat...
Thomas M. Daniel, The history of tuberculosis, Respiratory Medicine, Volume 100, Issue 11, 2006: www.sciencedirect.com/science...
Biblical references to TB: academic.oup.com/cid/article/...

[@Biographics]

To start comparing quotes and simplify your insurance purchase, check out Policygenius: policygenius.com/BIOGRAPHICS. Thanks to Policygenius for sponsoring this video!

[@JVEVI]

Hey! Do you have a Vincent van gogh biography?

[@JVEVI]

And why does it say you made this comment a week ago 🤣

[@flushedphoenix81]

@@JVEVI the comment is likely from when the video was originally uploaded with a future date to be public

[@bakalakastan]

Keep up the excellent work guys, thank you for all the effort you all put into these videos!

[@paddyoreilly8335]

You failed to mention this is for USA Citizens Only. Very disappointing seeing as we now live in a Global world thanks to Facebook meltdown.

[@rockgod6180]

If only Arthur would have coughed in Micah's face

[@ashtonwilliams4016]

Ong

[@ashtonwilliams4016]

Or never collected that money for streuss

[@camilasuarez4596]

F*cking Strauss…

[@JoeMartinMusic]

Man you beat me to it. Oh well, at least John sorted the issue.

[@Erik_m509]

He should have never gone to the Downes Ranch lol

[@gleam6370]

*I’m really sorry for you, son. It’s a hell of a thing*

[@samualbrown56]

Heartbreak in a single sentence

[@E-0921]

“I gave you all I had”

[@blakelong5544]

Lights up a pipe*

[@j3_designs_426]

_Does this trolley go to Tahiti?_

[@justinlabrosse8506]

We need more MONEY

[@hovancuong9226]

Tuberculosis took a toll on me, but igrotum is bringing me back to life. A true blessing.

[@ansonthomas2962]

What is Igrotum?

[@akaPixelChick]

I had TB when I was a small child, the treatment for it destroyed my thyroid, scarred my lungs and other things, I’m only 42 now, I’m in a wheelchair and my health is rather poor. Don’t underestimate this disease.

[@janicesullivan8942]

Very sorry that TB took such a terrible toll on your health and body, it is a terrible disease.

[@samanthabrown8467]

I had it twice once as child and early 20. The treatment was painful. My lungs of course are scared but also have nodules as well.

[@dinesandinesan9812]

@@samanthabrown8467 at what age u had it first time?

[@jujutrini8412]

A timely reminder that fatality is not the only thing to fear from these types of diseases. I am sorry it left such an impact on your body and your life.

[@ingGS]

I had TB as well, I acquired it as a child and I can confirm the treatment is very severe, it can destroy your liver. While taking the medicine (which takes MONTHS) it is imperative to avoid alcohol and other drugs that might interact with it. It is that serious.

[@ballinlikestalin878]

You missed one important figure who was hugely impacted by TB and was a great poet. Edgar Allan Poe lost his biological mother, his step mother, and at least a few lovers. The disease is the direct inspiration behind some of his most famous works, like Masque of the Red Death.

[@ians5597]

Yeah it had a big impact on Poe and clearly was a spectre over his existence, but 100 years later it was still claiming great authors like George Orwell. It's true that people nowadays think it's some antiquated disease belonging to a bygone time, or it's been completely eradicated like smallpox. But that isn't the case unfortunately, it's still a very real thing for a lot of people 😔

[@ShahrukhKhan-nj9lo]

@@ians5597 Yes its still a very real thing in developing countries. I'm from India and it was a morning of december 2018 when I woke up with my mouth full of blood and for a few minutes I kept puking blood even though there was no pain and the cough was uncontrollable. I was admitted to a hospital and was diagnosed with TB. Doctors told me my case was severe, I was on bed for more than a month and the medication went on for 12 months. A few years back 2 of my friends who are brothers were diagnosed with it and medicated. Even though we take care of eating healthy and cleanliness and drinking water through a water purifier only still it happened despite all precautions of avoiding such diseases. I started reading recently and found out writers like Franz Kafka and George Orwell, many of them succumbed to the disease in those times.

[@ians5597]

@@ShahrukhKhan-nj9lo Wow, glad you're better now then, we have a lot to thank advancements in modern medicine for! Like you say, and as we know from the Covid-19 nightmare, you can be healthy and live as well as you can but it only takes one instance of coming into contact with a virulent bunch of microbes and things can turn bad VERY quickly 😔

[@dsnodgrass4843]

One could also discuss the case of author Thomas Wolfe (the elder); who was in many ways the opposite of Poe, a hale giant of a man. He died from tubercular meningitis at the age of 38; despite the most radical medical interventions available in the late 1930s.

[@musicaddict1046]

I get your point, however I think he was only listing some artists who actually died from it, not who were affected. Otherwise another important one would've been Edvard Munch, one of whose paintings was even in the video. But as you might already have noticed, there simply would've been way too many to list if that was the criteria, so I don't think he was wrong in not mentioning it. However I still think this is nice to know, so thank you nonetheless.

[@mikdan8813]

Person in 2021: (coughs) I hope it's not Covid. Person in 1821: (coughs) my time has come.

[@tasosdiaforetico7377]

Anti vaxxers be like, hold my Neanderthal thought process

[@morenitomoreno1282]

The Maverick Mind lol how ?

[@Nedula007]

@@morenitomoreno1282 well, for starters global warming wouldn't have happened. We wouldn't have clueless idiots with stretched ear lobes and purple hair , society would be truly free , ..... did you know that ancient humans used to spend 4 hours a day eating , and that the modern human diet with ease of access to food has made our mouths smaller and flatter ? Neanderthals would also have the added benefit of having stronger gut bacteria and much more resilient to viruses and diseases. .... sure , there's pros and cons. As with everything in life.

[@wentoneisendon6502]

Covid is overblown compared to this

[@crazylizard1889]

I once coughed, thought it was nothing, went to school, coughed into my mask, saw blood, was diagnosed with TB, and caught Covid simultaneously in the hospital. BAAAAAAADDDDD. It benefits me as I'm now able to tell the difference between basic coughs and PROPER coughs

[@oldmech619]

My wife was undergoing chemo for breast cancer. It activated TB due to her depleted immunity. Doctors didn’t want to go near her. It’s dangerous to family members. I have been tested. She is missed

[@spacekid9680]

RIP {:,(

[@adamvose2651]

I'm so sorry for your loss

[@xyz7572]

That’s awful, I’m so sorry. In my country, all doctors have to get vaccinated against TB and several other dangerous diseases as part of their education, so that they won’t get infected by patients and won’t feel the need to avoid patients they’re supposed to treat. It’s absolutely awful to hear that your wife’s doctors didn’t want to go near her. Treating her was literally their job. I’m so sorry your family had to deal with medical practitioners acting like that, on top of everything else. I hope you’re doing as well as you can, considering the circumstances. Losing a loved one is never easy. I lost my infant child to cancer, I know how absolutely indescribably painful it is. I hope you know that your wife would want you to be happy. She knew she was loved, and in the end, that’s the greatest gift anyone can ever give anyone else. And you gave it to her.

[@dyfrigshandy]

Hmmm rip

[@Annnoura]

Sorry for your loss and thanks for sharing

[@method341]

I like how you branch out from biographies to conditions like this. Don't listen to the downers and keep pumping out great content.

[@NagoBust]

you are big gea

[@nielsssg]

This dude is massive. I doubt he has time to read comments.

[@mollybrown9857]

I'm hoping for a possible branch into other human species. That would fit in with the show.

[@tomlxyz]

What downers?

[@joeyr7294]

Well it is technically biological

[@nahnopenopenope3406]

once, a bus in my school with 75 students on board was exposed to a single student who had tested positive to TB, with symptoms. It frustrates me that her parents simply said “Oh, you’re not THAT sick!” without taking her seriously and endangered so many others instead of keeping her home! It also frustrates me that we live in a time where schools will punish parents for keeping sick children at home, where they need to be. It also makes me curious to wonder… if people felt sick, and stayed HOME, how bad would Corona virus have gotten?

[@powderstone8187]

That is a great comment. Shaming people for being human is irresponsible, and it leads to pubic health concerns.

[@nahnopenopenope3406]

@@powderstone8187 Thank you. We should treat communicable diseases with genuine compassion and concern for the human who has the disease AND other humans who could be exposed to said diseases. We also had an outbreak of scarlet fever in my elementary school that absolutely ran through the student body SO fast. Teachers and students alike got it. My area in the US also had a MASSIVE outbreak of typhus, and wiped out -towns- because there weren't enough doctors, and poor families didn't have access to care, time off, and quarantining themselves properly because they would be -fired-. History repeats itself. Covid is still running rampant in my area.

[@mizzinfamous9746]

Yea your right but there is a bit of nuance to that. Not everyone has the financial means to stay home but your correct tho

[@leechowning2712]

Early in 2020, call it April or May, the bank in our little town posted advice to protect from Covid. One of the top was "if you feel sick, stay home". Every time I saw it, I thought of the workers here. Almost all of us were "essential workers" and low income where staying home 3 days is enough to cripple the family income for a month. I pay 1/4 of my income each month just in rent. It would have saved thousands of lives, but until the working world changes it is not an option. The same for kids, since many families both parents work.

[@SovereignTroll]

A poor theory with follow the misinformation thrown in.

[@icemanire5467]

This was a massive killer in Ireland when my grandmother was growing up. It wiped out families. She also contracted it and I'm pretty sure it killed her mother.

[@lachlancuffe4081]

Reading Angela's Ashes taught me this very well.

[@mrsmucha]

Killed my great grandmother in Slovakia.

[@janicesullivan8942]

@@mrsmucha TB killed my paternal aunt in 1920, at age 20, and my mother had a lung removed in 1930 due to TB. It was a horrible illness.

[@sentimentalmariner590]

@@lachlancuffe4081 such a beautiful memoir. I still get teary eyed when I think of it.

[@powderstone8187]

Oh, wow. Thank you for sharing that with us.

[@edzmirredzuan9579]

Great video Just finished RDR2 when this popped up, talk about timing I feel for Arthur Morgan even more now

[@ironsmack10]

I literally finished the game for the first time 3 days ago lol

[@fromulus]

Noobs

[@ajm2872]

C3PO

[@edzmirredzuan9579]

@@ironsmack10 we in the same boat

[@praxis6172]

@@ironsmack10 same!. I just have too many games to play.

[@artemisarrow179]

“You can’t even kill a dying man.” -Arthur Morgan

[@TheShizz011]

My great grandad contracted TB in Burma during WW2 and lived with one lung for another 50 years (he smoked a pipe everyday) and was a beast

[@jr2904]

That generation was made of strong stuff

[@tasosdiaforetico7377]

Was he Ozzy Osbourne?

[@Nedula007]

They don't make em like they used too.

[@piggynatorcool668]

Lung cancer probably combated the TB tbh

[@thingsyouhavemissedoutonti8185]

What did he smoke? Lemme try that good stuff. 😁

[@theinventionshouse9232]

as one who has survived TB, trust me, it does waste you away. I lost so much weight, and was merely 47kgs for a 6'2 tall person. Feed well, take care of yourself and have regular checkups coz once your immune system goes down, TB comes out to play.

[@gingercube688]

Holy cow 47kg is scary Did you have loss of appetite, or was it too hard to eat around coughing, ir did eating make you feel awful? I'm trying to understand how it has that effect

[@ayakotami3318]

You too? I got it myself in the early 2000s. One of the worst few months or my life. 😓

[@LeoDomitrix]

We live in terror of it with my hubby, who has NonHodgkins Lymphoma.

[@YukiLuvsJesus]

What is 6’2 in cm

[@haikalmiftah2529]

​@@YukiLuvsJesusLittle more to 180 cm

[@doclewis8927]

A friend of mine had TB in high school. She disappeared for 3 months. Thankfully, she got better and was able to return to school. They also caught it before she had given it to anyone (as far as I know). She had to tell all of her friends to get tested. I still have myself tested from time to time because we spent a lot of our lunches in her car. If you're out there, J.B., I hope you're living your best life and are happy & well! Love ya!

[@salinium]

"I got TB. I got it.... beatin' a man to death, for a few bucks."

[@walmartbag5698]

Biggest mistake arthur ever made in the game

[@fricki1997]

I'm studying Infection Biology, and I've set my aim afterwards on one of two pathogen-caused diseases, either Malaria or Tuberculosis, because they're the two single organisms responsible for most deaths from infectious diseases nowadays. Tuberculosis in particular could make a comeback even in first world countries if antibiotic resistances to first and second line treatments continue to spread. Very nasty stuff, and about 1/3 of the world population is latently infected. I spent one internship on testing a potential antibiotic candidate on lab surrogate organisms.

[@ryanatkinson2978]

You're doing massively important work, thank you

[@Tacitus-qd3ev]

A very worthy call, on behalf of humanity I thank you.

[@jakeg3126]

That’s why everyone should get their childhood vaccines early as possible right? Then it won’t or might not get drug resistant, kinda like take all 10 days of pills, not stop when symptoms are gone

[@fricki1997]

@@jakeg3126 Sadly it's not that easy. The childhood vaccine only protects against meningitis caused by Mtb in newborns, not against the pulmonary tuberculosis in adults. So far there's no vaccine against that - there have been many attempts, but no successful ones. A problem might be that the outer cell wall of the tuberculosis bacteria (which is exposed to immune cells and antibodies) mostly consists of very long fatty acids, so only little protein is exposed - and our adaptive immune system mostly recognizes proteins, not fatty acids. But otherwise you're absolutely right - early prevention is much better than treatment later for any disease I know of.

[@jakeg3126]

@@fricki1997 Like maybe 7ish years ago, I had a viral pneumonia and was unable to oxygenate enough so the put me in medical coma for I think 10 days and hooked me up to an ECMO machine to oxygenate my blood because my lungs were scarred up and infected. Before that a had 2 blood stem cell transplants. So now I have to give myself an IGG shot to boost some odd number or something up and it somehow has like a herd immunity thing because I think its made from serum of a bunch of people so cells aren't 100% programmed yet. I don't know if a lung bypass machine and prey infection disappears might do anything; except maybe if it heals would you have potential immune system cells for vaccine? could boosting igg levels work?

[@ignitionfrn2223]

1:05 - Chapter 1 - A body consumed 3:45 - Chapter 2 - Million years war 7:15 - Mid roll ads 8:35 - Chapter 3 - 1 in 4 four deaths 11:00 - Chapter 4 - An interesting way to go 13:35 - Chapter 5 - Heroes in lab coat 18:05 - Chapter 6 - Still a top killer

[@prapanthebachelorette6803]

Thanks

[@birb9804]

Chapter 6 Arthur succumbs to TB rip

[@Postal_Dude622]

No... Lemmie fizz it Chapter 1: I PAYED MONEH FOR THIS.. MAKWNS Chapter 2: this game is fine I guess.. Chapter 3: I like this guy Arthur! Chapter 4: *INTENSE BANK ROBBERY AND BOAT CRASH* Chapter 5: NOOO HE HAS TB SIQJJDIWH2JS881JE Chapter 6: Mayyy iiiiiiiiiii stand unshakennnn I neeeed something specialllll" *INTENSE ｡･ﾟﾟ*(>ддд

[@otherpatrickgill]

I'm a South African who has worked overseas as an English teacher. Before going I needed to provide x-rays of my lungs to prove I didn't have TB. While working I came down with a nasty persistant cough which eventually caused so much irritation to my throat that I spat a little blood. I got a taste of lockdown a few years before covid 19! Why were they so scared? Multi drug resistant TB is prevelant in my country and other countries were dead scared they'd catch it from me. Using too many antibiotics and feeding them to farm animals so you can force more of them into less space and get them to live in unhealthy and inhumane conditions to maximize profit; then feeding that meat containing low levels of antibiotics to people, etc had lead to the rise of drug resistant strains of deadly bacteria. Carry on over using antibiotics and we'll have multi drug resistant strains of Bubonic Plague.

[@carolinchrist928]

I am German and when I started working in Hungary, I also had to have an x-ray of my lung to prove that I am healthy. Havent heard of that in Germany before. Its still a thing nowadays

[@giwilreker]

And it's why in RSA the TB vaccine is given at birth with follow up boosters, especially because of our high HIV rate.

[@billpetersen298]

Oh great, China has taken mass pig farming, to a tall building level. Joy.

[@marcusjay8103]

Can we get an episode on Rabies? Having recently seen it mentioned and a short video of a man showing crazy signs of 'hydrophobia' and apperantly you can get it from a simple scratch from an infected animal, it doesn't have to be some deep bite, it attacks the nerves with 100% morality rate (apperantly). It can also sit dormant in the body for years before showing signs and thr video claimed as soon as you get the starting stage of a headache you are basically already dead and it's just a matter of a few days/weeks then till your horrific death, it was also stated that it's everywhere but the transmission to human is extremely low but again, 100% mortality if caught. Got me absolutely horrified now and I'm intrigued to learn more, but being lazy, can you just do the research for me and present me with a neat little video. You can call it laziness, but I prefer to look at it that really I'm just keeping your researchers employed and helping you get feed your family with Ad revenue 😉 I'll settle for a 20% cut, or you can use it to feed both Danny AND Calum.... My treat 😂

[@EclecticDD]

Cool idea, I'll add to it. Jeanna Giese the only person known to have survived rabies without having received the vaccine. What's my cut? 🙂 Edit: fixed her name back from autocorrect

[@blueberrypirate3601]

La Rage in French and Tollwut in German. Learned that at Channel ports.

[@jobieheiser443]

I saw that video too, I believe it was Lazy Masquerade? fuckin terrifying.

[@marcusjay8103]

@@jobieheiser443 Yes! Watched it this morning. Was regarding a video posted on reddit of a man freaking out about drinking water and then a specialist left the comment regarding all the facts and giving an example of a 6g Bat just scratching your knee while camping etc while the bat is basically freaking out dying of rabies himself and can infect you without you even knowing. Am now terrified to leave the house just incase 😂 Though being in the UK I don't see too many bat's but the way they explained that rabies is all around us but rarely pass from animal to human really shocked me. Was a super interesting video and a great channel too. You have great taste in content 😉

[@slapchop133787]

My great great grandfather died of Rabies. He got so crazy that he was eventually tied to a bed and left to die a terrible death from dehydration. I wouldn't wish this disease on my worst enemy. Terrible stuff.

[@tristanjackson5343]

“ I think I’m dying sister, I got TB yeah, all for beating a man to death for a few dollars”

[@draken571]

I like how Simon has a different personality on every other channel he has.

[@kakacookiemonster7639]

makes me wonder how the Biographics mr simon keeps in Brain Blaze mr simon

[@draken571]

@@kakacookiemonster7639 He did say he tested medicine for pharmaceutical companies when he was younger.

[@jessiejones6633]

You can tell how he feels about the subject of the moment by how he acts. Subjects he likes or is fascinated by he's almost bouncing in his chair. Subjects involving human stupidity and he turns the sarcasm knob all the way to 11.

[@pixiesouter9419]

When I was seventeen our year in high school were all told that the BCG was being offered but, as TB has mostly been eradicated in the UK, it was no longer mandatory. So I'm one of the first generation not vaccinated for it. This freaks me out when I travel because I need to do research on wether or not TB is a problem where I'm going. But I refused it because my older brother and sister had just spent five years showing me the injection scars they have and teasing me about it. So by the time it was offered I was terrified. Anyone under 18 reading this: if they offer it to you, take it. The benefit way outways any pain or fears.

[@rynomc9351]

Having grown up near Waverly Hills Sanatorium, it was easy to be grateful, at a very young age, that a cure had been found nearly 60 years ago. Especially when living in a damp valley.

[@didemsakura5473]

My dad had TB. Thankfully, he is now cured/ cleared after 9 months of treatment. Believe me, the disease is nasty as well as the side effects of medicines they take everyday. I remembered my dad took like 20 medicines consisting of pills and injections on his first few months.

[@rafaelbrisolara7599]

One of my best friends from childhood died because of it. He contracted the bacteria in a hospital while he was there for another issue. It was a multi resistance variant and the doctors couldn't do much to help him. I was truly shocked when his family gave me the news... he was a healthy and talented young man...

[@Naturegirl1976]

Sorry for your loss

[@Postal_Dude622]

I though this was gonna be a Arthur MORGAN joke

[@debras3806]

May i ask in what country and decade?

[@rafaelbrisolara7599]

@@debras3806 it happened in Brazil, about ten years ago.

[@HistoLabRat]

Working in a histology lab I am fairly sure that Carbol Fuchsin is the dye used to stain Mycobacterium Tuberculosis. The Methylene blue is used to stain the background and help make the bacilli easier to see.

[@odyssea-the-seeker]

Koch himself documented his staining method using methylene blue and KOH. I think carbol fuchsin was developed after Koch's discovery to improve the method for staining mycobacterium.

[@juancana457]

Heaven help you if you 'show-up' Simon; careful.

[@shatbad2960]

Should do a show on Typhus. Sadly, a lot of people died from this in the work camps during WW2.

[@loudog3998]

Isn’t that what killed Anne frank and her sister

[@alexs5744]

@@loudog3998 Yes.

[@Maderyne]

It's amazing that the disease has stayed with humans for so many centuries. I remember as a child being inoculated against it along with the other childhood diseases. I wasn't aware of its deadly reach across the span of time! Such a persistent disease it is.

[@namename-tr8il]

can you repeat that in english

[@janicesullivan8942]

@@namename-tr8il Read slower, you might understand what was said.

[@Jin420]

@@reg4211 if you're referring to immigrants -- for the "... testing people coming in." Comment ------ They [government/healthcare] might not test certain individuals because of the BCG's potential interference with tuberculin skin test reactivity. BCG is a TB vaccination Reaction to the skin test is also possible with other vaccinations from other countries. If people are coming from countries where TB is more common, then it's most likely that they've received BCG. s/n: BCG is not generally recommended for use in the United States because of the low risk of infection with Mycobacterium tuberculosis, the variable effectiveness of the vaccine against adult pulmonary TB. Stay safe & have a great day 💕

[@kermi4]

RIP Arthur Morgan gone but never forgotten

[@InquisitorThomas]

God Damn it guys, stop posting Red Dead Redemption comments… Any way when are you going to do a biographic on Lumbago, it’s a slow and insidious killer.

[@TimSnead223]

It’s a slow and painful death, my brother.

[@alexandershin413]

You got us in the first class I’m not gonna lie

[@muzzer5327]

Loleth

[@CafPhine]

Space Shuttle.

[@s.crawford12]

We will only stop when the death of Arthur does not hurt anymore.

[@anedgedancer5147]

Thanks for doing an episode on this. I contracted TB when I was younger, 21 at the time. I was lucky to have caught it in time to receive antibiotics and was quarantined for 2 weeks with constant sputum and blood tests. I'm well now, but the battery of antibiotics and the damage it did to my body like my liver and lungs, are still kind of felt today. Ugh, the antibiotics were so bad lol

[@c_6951]

Same. I caught it when I was around 12. Now this video has me scared about it becoming active since he said it could do so within 40 years 😭

[@stigmatafan09]

@@c_6951 if you don't have a latent TB infection you have nothing to worry about. A simple blood test can determine if you have a latent TB infection or not

[@gudmundursteinar]

I think it's a sign of progress that the premise of this video has only been true in my lifetime. Before then it was "Smallpox: Humanity's Deadliest Foe"

[@JustAnotherAccount8]

It's crazy that TB was romanticized back in the day and yet, the bacterial relative that causes leprosy had the complete opposite reaction from people. (TB and Leprosy are related as they are both different strains of the same Mycobacterium bacteria)

[@Alex-mq6qi]

Morality has aesthetic criteria. Having your body falling to pieces is certainly uglier than coughing some blood here and there. That, and people are stupid as all hell

[@TwentyNinerR]

TB is so prevalent in Indonesia, it's officially the nation's deadliest contagious disease. Also, Indonesia's Ministry of Health report showed that we have the third largest number of TB-contracted people in the world. Reports show that overpopulated correctional facilities are one of the most prominent TB clusters here.

[@honda-akari]

Muslim country 🥴

[@ActionJackson669]

That's awful, on SEVERAL LEVELS‼️💯 I'm sorry to hear that, friend. I've never met anyone with TB, or that HAD TB to my knowledge. But I guess I don't go around asking all the time.

[@Quantum-1157]

Just be thankful you are not in India! Literally millions are infected in the latent state.

[@trishapellis]

I just realized why I like Simon's channels so much. It's basically like watching something like National Geographic or Discovery Channel where they don't pad 15 minutes of content with 45 minutes of images, repetition, and five-word sentences. Now all I need is for him to start a channel with 15-minute explanations of interesting space phenomena, and he'll be the replacement of all educational TV I've ever wanted to watch. (Bonus points for Casual Criminalist, as I don't think National Geographic ever did biopics of serial killers)

[@plushman3685]

Arthur Morgan led me here. He gave his best to you Dutch-all he had.

[@nora768]

Very interesting. My mother died of TB Menigistis 30 years ago this year. It was a shock as we found out the next day after she passed from the Health Department insisting we all attend their office for a TB test. I felt especially bad for my grandmother as she lost her sister to consumption in her childhood and then her daughter. As a side note, the TB was spread by three immigrant students that attended the college my mom was the registrar at.

[@davidegazzaniga7558]

During the first wave of Covid, here in Italy, my dad who is a doctor had to treat an active TB case in his rural hospital, since all major hospitals were full and infectious disease wards had no places left. Scary stuff

[@Docsporseen1]

I worked in military public health for 15 years. TB exposure, while not common, wasn't rare either. The advent of the PPD test showing exposure was a massive advance in the treatment and prevention of TB.

[@davidkugel]

Every five years a teacher in CA must take a TB test. We do get students from all over the world who may be TB positive.

[@JazzHalesBabyGurl]

My great-grandfather passed away from it at age 31. My grandfather and his sister both contracted it, but were able to recover from it at 3 & 5 respectively. They have both since passed on.

[@neuronoerd]

Being home from work for over 5 weeks Now with injured back-muscles, I’m so freaking thankful for you and all your channels. Always something to watch and something New to learn!

[@Rakeshgupta-iy7lm]

Hi can you make a video on Desmond T Doss the first conscientious objector to win the medal of honour and on which the movie Hacksaw Ridge by Mel Gibson is based on.

[@ScaryBaldMan]

Still say you should have a channel dedicated to stuff like this. Call it "Biologics."

[@AnGhaeilge]

I've been working on my family tree for some time, and I didn't appreciate the impact of TB until I saw the huge amount of deaths from it in my tree. So many died so young. It really was a horrendous disease.

[@TheHorseOutside]

Caoinim duit a stór, sin uafásach

[@trevscribbles]

@@TheHorseOutside An bhuil cead agam dul go dti an leithreas

[@TheHorseOutside]

@@trevscribbles tá

[@trevscribbles]

@@TheHorseOutside Go raibh maith agat

[@Kiki-mf8gc]

When researching my family tree I was perplexed. A whole branch of the family left Ontario, Canada for Colorado and died there. They ALL died within 2 years. Then a little more research revealed they moved there for TB treatment...

[@dagmar0904]

Just a small correction: The bronte sisters didnt all die of tuberculosis. Charlotte died most likely because of hyperemesis gravitum (cant stop vomitting, while being pregnant), its not sure if tuberculosis or pneunomia that led to the death of emily. Anne was the only one where we are sure that it was TB

[@micheledeetlefs6041]

Thank you for pointing that out. I was about to throw Elizabeth Gaskill's biography of Charlotte at his head.

[@squeezme88]

Wow, I had no idea that TB was so prevalent still. Thank you for opening our eyes to this, and hopefully those targets to eradicate it will be met

[@axis1198]

My Uncle (Mom's brother) had died from internal bleeding last July 2019. The most frustrating part was that everyone in the family and our relatives knew he had TB and had been reminding and warning him about it but he himself did not bother caring for himself. He did try to maintain his meds and lived in isolation in the fresh air of the mountains, but his addiction to alcohol, smoking, and drugs only shortened his days. It may be due to him missing his deceased wife that he no longer bothered to live on. 😢 He is at peace now, and may his soul find rest.

[@stacyrussell460]

My daughter tested positive for TB when she was a year old, but did not actually have active TB. Freaked us out bc she was always with us or home babysat by her grandmother. We all had to get tested & were negative. Somehow she had been exposed to someone with active TB. Doctors say she'll likely always test positive now.

[@BRUXXUS]

Similar thing happened to me as a really young kid in the mid 80's. Not even sure how or why I was originally tested, was exposed. I had to take this really awful antibiotic syrup every day for like a year or something. I remember HATING when it was time to take it. 35 years later and I can STILL remember how that crap tasted. lol. I still test positive for TB with a skin test. The more thorough and expensive blood test will show negative, though.

[@igostupidfast3]

My mom still tests positive after getting it over 50 years ago as a baby

[@stacyrussell460]

@@BRUXXUS oh, wow! That must have been awful. Thankfully my daughter didn't have to take any medication. They did a blood test to determine she was negative.

[@stacyrussell460]

@@igostupidfast3 yeah, my sister always tests positive for TB after she worked in a nursing home. Note: this was years before my daughter was even born & doctors determined my daughter's positive reaction was not linked to her aunt.

[@sundevil2295]

I just had to get blood work to test for TB. I am about to take Remicade and read on a forum that a woman tested positive for TB after her second dose of Remicade. Really hope I don't get it.

[@Elora445]

My great great grandmother had TBC and sadly died from it at quite a young age (36). She had five kids, but luckily, none of them got it and all survived to old age. Guess she ended up at the hospital quite quickly. TBC is an awful, awful disease. So glad we have vaccines nowadays.

[@danielfortier2629]

Tuberculous is a very familiar name in my mother's family! In the 1940s and 50s my maternal grandmother was forced to go to the TB sanitorium three times, spending a total of five years while raising 11 children! On the eve of an operation to remove one of her lungs she caught a flu. The chaplain of the sanitorium prayed a novena with my grandmother and once she had fully recovered from the flu there was no trace whatsoever of TB. It was a miracle that the doctors could not explain. My grandmother never was sick from TB ever again! Unfortunately not all of my other extended family members were so lucky. My aunt caught TB and spent a while in the sanitorium at the same time as her mother. It didn't hit her as strongly and she recovered. My eldest uncle caught TB and went to the sanitorium. He died from Tuberculosis Meningitis at age 22. A younger uncle caught TB as a young man and he had to have part of his lungs removed. He recovered, but I remember the scars from the surgery. Also, my own mother was hit by TB. In November 1952 my mother was 23 years old and had just given birth to her fourth child. She was already exhausted from taking care of her own kids and childbirth, but she also had to go take care of her father and several of her younger brothers because her mother had just been sent to the sanitorium for the third time. This is where she caught Tuberculosis. Three months later she had to be placed in the sanitorium too where she shared her ward with her mother. My mother had to stay at the sanitorium for a full year! Since the sanitorium was 745 km (463 miles) from home, the kids could not visit. The two eldest visited only once, and that was six months after she left. My brothers' separation from our mother provoked some lifelong psychological problems especially for the second oldest. After a year away the reunion was very difficult for the kids. Two of them didn't even remember their own mother. My mom's heart was broken. My mom had four more kids after the TB, and she remained very weak because of the TB the remainder of her life. As children, every September we had to go to the health clinic to get our yearly TB vaccine. Although our mom had TB we were doubly at risk because our dad also tested positive, even though he never got sick. So TB is a four letter word in my family! It devastated a lot of lives for nothing!

[@jasonhutter7534]

Your mother is a warrior. Two kids after TB? That's incredible. What a tough lady. I cry like a baby when i get the flu.

[@chefjrmz]

I literally just got done watching Tombstone with the ever famous character Doc Holiday who suffered from TB. As watching it I wanted to know more and find this new vid up. Simon is always there for us!

[@lydan5808]

I'm your huckleberry

[@deazl666]

Doc caught it from his Mother I believe

[@12227UserName]

@@deazl666 Who knows how he got it. He did have a profession as a dentist hence his nickname "Doc." It's possible he received it from one of his patients. Interestingly, he lived for quite a while. Most people who got TB around that time period lived for only about 5 years at max. Doc on the other hand lived closer to 10 years or so, if I remember right.

[@ThorMan91587]

12:00 while we're on the subject, I think Keats is long overdue for getting the ol Simon treatment.

[@tomhoney5112]

Really enjoying these types of videos Simon. Keep up the good work 👍

[@aidanwatson910]

Every single one of these videos slap. Keep up the great work I'm learning a lot.

[@catharinepizzarello4784]

Beautiful, Simon! Thank you so much!

[@jah211084]

Great stuff Simon and team, very interesting

[@December954]

I really love these ones on diseases and plagues etc. They’re super interesting. I watch the biographies when Im super bored, but I watch these because I really like them

[@vlad3k660]

i am a respiratory physician in Romania and I congratulate you for this great presentation!!!

[@sleepdrone3642]

It got my boy Arthur Morgan. Never forget

[@travio995]

🔥🔥🔥

[@lumbagoboi1649]

Normal people: Tb sounds awful, Glad they can treat it now! Rdr2 players: 😭

[@timcollum5015]

I really need Simon to say on camera: "Tea: earl grey. Hot.". He would verbally intimidate Jean-Luc perfectly. lol

[@austinfriend1048]

This is some kind of amazing! So very interesting! How we figure this stuff out and collectively work together to defeat the enemy

[@donsandsii4642]

Thank you Morris M. For your research into disease and other topics

[@hanadeflour]

I just witnessed my neighbor died of tb before my eyes a few months ago. It was terrifying and heartbreaking. I can still remember vividly the look on his face and how he was carried to the hospital on his last breath

[@SupermarketSweep777]

I had to get a TB test for clinicals in 2018 and came back positive for Latent TB. Lot of meds needed to flush it out.

[@debras3806]

May I ask why it's needed to flush it out since it's asymptomatic?

[@SupermarketSweep777]

@@debras3806 Because you don't want it to wake up from its slumber when your immune system is compromised.

[@torietorreano6613]

Fascinating as always!

[@Tomdabomb86]

Great work as always

[@normannippy8471]

As a newly-dignosed TB victim, I found this video highly educational and forwarded in an easily-understandable straight-talking format.

[@deussivenatura5805]

You clean now?

[@normannippy8471]

It took the medical profession 7 weeks to change their minds and tell me the 'good news' that I didn't have TB but a severe case of pneumonia which six months later I've just about recovered from

[@ktmadison588]

Dear Simon I believe it's time for a Biographics on Aleksandr Solzhenitsyn. You say how well videos on the Soviet Union do on most of your many channels, yet I checked the Biographics channel and was amazed you haven't got round to it yet. The Gulag Archipelago was based on over 200 survivor's and his own recollection of his 11 years in the labour camps which he committed to memory. After he was released keeping the whole thing from the authorities was indeed a challenge in its self. In comparison you do have one on Pierce Morgan and the best thing he did was to be punched by Jeremy Clarkson.

[@gabigrace9136]

A video like this would be amazing covering Dungue Fever! Love your work!!!

[@bryonyfucile3979]

I bloody love these videos. Any chance of a new channel dedicated to diseases? 😂

[@hectorsmommy1717]

My Mom grew up on a dairy farm and went to a college that was in the heart of farm country. Everyone had to get a TB test and, if they showed positive, a chest X-ray. There were so many who tested positive that they bussed them to the hospital for the X-rays but pretty much every one of them tested positive because of exposure to the bovine TB (this was around 1940). One great grandmother died of TB at age 32. She and her sister spent time at a sanatorium in Colorado but it did no good.

[@janicesullivan8942]

My mom had a lung removed in 1930, and like your grandmother, she also spent time in a sanitarium. She said family would visit her from the other side of the window.

[@annaellemay8590]

A girl in my yeargroup was diagnosed with TB. Her whole class was quarantined and tested. They were all fine but it turns out that one student who often frequented my class had latent TB. People didn't know the difference and she was outcasted. It hurt to see her avoiding us because she was afraid that we would say mean things. I knew the difference thanks to my random internet knowledge and I helped her to warm up again to us. I encouraged her and explained to others that they're different and that she wasn't spreading anything.

[@fuzzyworld3]

Fantastic segue from tuberculosis to life insurance, Simon!

[@LennysaurusB]

Another classic video thank u facts man

[@deeznutz4421]

Thank you for your videos. They’re the only thing that can put me to sleep. I have insomnia

[@denefbla]

My good friend Arthur died a while back. He had tuberculosis. In the end he tried.

[@janelightning73]

Very informative. Thanks.

[@randalllake2785]

Excellent presentation

[@williamdrijver4141]

Very informative video, especially considering the current pandemic. Always good to learn from the past. And to realize that past still is the present in some parts of the world.

[@SzymonGasiorowski]

RIP Arthur Morgan.

[@sarahs.7211]

I just subbed because I realized I have been watching your videos for 3 days pretty much nonstop.

[@donaldmclaughlin7977]

Just come across this in late November 2022. Almost as I watch this a news announcement has reported the first confirmed TB case in the UK in decades. Keep up the great content.

[@tracyphillips4445]

I live in Australia and in 2021 my son had TB. He started showing signs of having TB when he was 3 months old and it wasn’t until he was 8 Months old that Doctors at our local hospital finally realised it was TB, he was treated by the amazing people at Melbourne RCH, and now has fully recovered. The scariest part wasn’t so much that he was sick with TB but the fact that a lot of doctors and nurses at both hospitals had no idea what TB was, and most of the ones that did know of the disease thought it didn’t exist anymore. I wish this video was available when he first got sick. Love your stuff Simon keep up the good work guys.

[@librasgirl08]

10 years ago I was informed by the centre of disease control, that I need to get tested for TB. One of my former colleagues had gotten TB. And not only did we work on the same office floor, but different project, no, at least twice a week, we took the train together and spend lunch breaks together. The whole company had to get tested. We got appointments and a paid day off. And we're in Germany, not where you would expect a TB outbreak. The colleague survived and as far as I know, no one else tested positive.

[@ritemolawbks8012]

-I'm not xenophobic or racist at all, but could it have come from the spike in migration (not just Syria, Middle East, and Africa)? There's drug-resistant strain from Russia and Ukraine as well.- EDIT: Ooops. I didn't read the first three words.

[@librasgirl08]

@@ritemolawbks8012 I'm really wondering where you saw racism in my comment...

[@ritemolawbks8012]

@@librasgirl08 I was referring to my own comment that sounded xenophobic, not yours. I originally asked if the TB outbreak could have been from the increase in migration to Europe; and then I noticed you started with "10 years ago[,]" which was before the _Arab_ _Spring,_ _Syrian_ _Civil_ _War,_ and the EU migrant crisis. There was NOTHING racist about your comment at all.

[@bisiilki]

Great comprehensive video

[@billvinson7859]

Thanks. History of medicine is always fascinating.

[@glasswhisperer]

"I can just retire to my Summer Home in California" Also Simon said it takes up to 40 years to show symptoms, more like 40 days amirite?

[@BalkanRedneck]

*country club

[@deazl666]

Up to 40 years probably

[@fromulus]

It could take a long time, could take a short time, depends on the individual

[@pakde8002]

40 years in cases of latent TB

[@saradapagediocletian9707]

I've been to Mercy Brown's grave and while I don't believe in ghosts there is definitely an aura of sadness there.

[@Numbers21589302]

This is great, would love if you did a history on malaria as well.

[@trhoades2063]

Loved this!!!

[@irvinbohac8460]

I think your channel is amazing. I love the combination of both medicine and bios. Also- could you do a biographics on the Bosnian and Serbian war in the early 1990s?

[@tgmccoy1556]

My family was affected by TB my Pop had it as a young man . Also scarlet fever. My great aunt died of it as did her second husband. My late mother in law was exposed but never came down with it. She lost a brother and sister. I never drink unpasteurized dairy. The anime movie "The Wind Rises" accurately shows TB'S progression.

[@giasaveilli608]

I found out that I have Latent TB when I was 22. I read on the internet that I should have gotten rid of it before having children, but doctors never told me this, I'm confused. I don't know where I got it from. I had a great uncle who had it, and we lived in the house he grew up in, but that was over 40 years before we moved in. Can TB live on in areas without it's main host?

[@tgmccoy1556]

@@giasaveilli608 it's pretty tough but I don't know how long it can live outside a host. I am latent too but 68 and now test negative .

[@giasaveilli608]

@@tgmccoy1556 Wow! I am 54 now, and I wonder if I am still positive. I think I will ask my doctor to test me for TB, thanks.

[@tgmccoy1556]

@@giasaveilli608 you are welcome.

[@rosellaaalm-ahearn1760]

My mother contracted TB in 1952 and was hospitalized in a sanitarium for 18 months. One of the therapies that she had to endure was really awful. In addition to Streptomycin and Isoniazid, she had to receive air pumped into her abdomen, (called Pneumoperitoneum). This was a dangerous therapy, and It's purpose was to compress the lungs to facilitate healing. It seems medieval now. and I don't think it did anything. Mother lived a long life anyway, happily.

[@grimfandango6137]

Great story Simon, just wanted to pump up the algorithms

[@specialperson335]

Can you make a video on either Mannerheim or Jean Sibelius?

[@christophermerlot3366]

The great author DH Lawrence was also felled by TB. Poet Percy Shelley also had the disease but he drowned before it could kill him.

[@em1osmurf]

as a child in grade school and adult in the military, TB testing was almost routine. this vid was on point, simon.

[@loudog3998]

They do TB testing when you go to jail and are there longer then a week prisons also do them