Tumour immunology and immunotherapy

[@Inspiration.U]

As a Medical practioneer..I can justify the amount of knowledge provided in such a easy and professional way....I will highly recommend it to my colleague's

[@noname8354]

I'm still a bio undergrad but some of the best literature I've ever read were from literature reviews in Nature. They're long af but extremely easy to understand a lot of the time, even for people without a lot of prior knowledge about these things

[@saddamalgafsi6721]

it's incredible how well it's animated and how concise and instructful it is!

[@zzagriff]

@@noname8354Narrative reviews are very good for basic sciences

[@dr.maryamabid9371]

As a practicing oncologist I must say this is by far the most easy and great animation on Immunotherapy I have watched.

[@MegaSantiago20]

Thanks for your work!

[@Flop1000]

I’m a doctoral student in Molecular Biology, and these animations are beautiful! I’ll be sure to use these with my classes!

[@DrBLOOD1995]

If all medical books were replaced by animations like these, medical studies would be less boring, more easy to understand and remember and more attractive.

[@rm9308]

You still need books.

[@Azuwww]

@tractor Wrong.

[@DrEru]

@tractor pathology: excuse me wtf!

[@MrSidney9]

Remember, medical doctors aren't scientists. Research on cancer and possible treatments are done by biochemists, oncologists...human biology/biochemistry is really hard. Harder than any other disciplines.

[@erickdanielperez9463]

The problem is that the animations are limited; Many times what is written in medical books, comes from the direct experience of those who have seen the complexities of tissues. In half paragraph describe more than this animation in 5 minutes, can not do.

[@mikaelfalk6720]

Awesome video, I really wish there were more animated videos like this one, that they were longer and more in-depth.

[@kaam6468]

I agree

[@dewaldsteyn1306]

Its resl life.

[@chazadanga]

Look up nucleus medical media.

[@jhaybryanpros964]

melanocytes

[@data790]

Life saver. I have to give a trial lecture on lung cancer and the immune system as part of my PhD defence. This video helped me understand all therapies thereafter. Thank you. Please accept one of my papers for publishing :)

[@MegaSantiago20]

How did it go? And a very big thanks for your research on those subjects!

[@data790]

@@MegaSantiago20 it went super well - if I remember. Was a fun day. Passed so all good

[@MegaSantiago20]

@@data790 Awesome!

[@remembranceproduction4395]

keep looking... keep finding... don't give up hope.

[@eleanorsheekey9573]

This video is EPIC! Makes much sense of the long list of names and roles of the non-transformed tumour associated cells!

[@anactualmango_]

i cant believe im going to be working with postdocs on cancer research and therapeutics for my research lab placement in my final year of college as a molecular bioscience student! this was really helpful thank you

[@ufatemav4509]

Imagine creating a video game for middle/high school students like the one shown in the video. Science integration in animations and games is truly an effective way to boost ones understanding of the concept!

[@SnrKagemusha]

Fascinating video. My only comment: someone should actually make that cancer-fighting version of "Space Invaders".

[@prantokumarsarker9460]

😅😅

[@crashjohnny_]

Exactly! 😂

[@mrniceguy4277]

I have a game called "Fungalinvaders" that already goes into that direction (as the name suggests, you fight fungi). But it's a shitty game

[@bradebronson8835]

Dr. Mario

[@vladbcom]

Good idea, I'll get on it

[@ahmadalmasri826]

This is definitely the best video I watched in all my medicine studies.

[@carlosfernandocastanedaola1612]

Thank you so much Nature video. Greetings from Molecular Biology, enviromental and Cancer Research Group (BIMAC) and Bioengineering graduate studies at Universidad del Cauca, Colombia.

[@lotfihamoudi3174]

Thanks for the video and we pray to God to heal all the sick

[@serogolemogole2685]

Agobebjalo🙏

[@donross7820]

No one ever talks about induced Innate Immunity and the interactions of Dendritic Cells, NK Cells, and Macrocytes. We all catch 1 million cancers every day but the cell receptors of these detect them and destroy the malignant cell. So eat your fruits and vegetables, exercise, maintain a slim weight, and avoid excessive alcohol! BTW, I love to create this type animation as a hobby and this one is especially beautiful. And Parham The Immune System is a wonderful book. When I went to med school I was taught things like "somehow muscles contract" and "somehow infections are controlled" but now it seems every step in every signaling pathway has been figured out. It is incredible (and so exciting) how much is now known about the immune system and all the new practical applications of that knowledge!

[@hashhoomy]

سبحانك ربي ما أبدعك، وعلم الإنسان ما لم يعلم.

[@erenyalcn9393]

Nice bomb plans

[@darrenanimatic9675]

What??? I'm no Arabic, but... 🔠🔡🔢🔤🅰️🆎🅱️🆑🅿️🆔🅱️🆑🆎🅾️🅰️🈁🈂️🈷️🈶🈯️🉐🈹🈚️🈲🉑🈸🈴🈳㊗️㊙️🈺🈵

[@MrZer000]

ignorant pricks

[@bity-bite]

@@erenyalcn9393 Haha. It is funny how fake media news fucked up your brain, what a racist. Do we need to talk about how is your religion just about sex "Christianity" (If you were a Christian), adultery, gay etc... Pfft

[@mary-cq2sz]

سبحان الخالق ما أروع خلقه!!!

[@Mariiiam]

Most interesting topic ever. I wish we could someday replace the chemotherapy/radiation totally with modified immunotherapy.

[@Lets_Talk13]

After the third chemotherapy session, he stopped eating due to severe mouth ulcers and was hospitalized again. Though stable initially, his condition worsened, leading to organ failure. Despite being on life support, he passed away the following day. I share this to urge others in similar situations to be extremely vigilant.

[@noemijesaminem.duenas818]

This channel deserves more subscribers because of its creativity and hardworkship on this fascinating animation video Well done😊😊😊

[@hanniballi]

I think there is a mislabeled point in video at 3:50. It should be labeled in regulatory T cell not Helper T cell.

[@KenJackson_US]

Remember, NK cells and their ability to sense stress-associated molecules came about by chance, as did helper T cells, dendritic cells, cytotoxic T cells, coreceptors, perforin and granzymes. Their obvious design wasn't designed. Never mind the effectively infinite permutations of a string of amino acids that had to be searched to find functional proteins.

[@billmorehouse2324]

Hare Kṛṣṇa Toward the scientific case for Intelligent Design (in Biology), a presentation from Discovery Institute Founder, Professor Phillip E. Johnson kzbin.info/www/bejne/fHXFhIGBmbmskNU Hare Rāma

[@brightobi5361]

Came about by chance? Balderdash!!!

[@KenJackson_US]

Yeah, it's pretty far fetched, @@brightobi5361.

[@Jesus_Resurrection_and_Life]

I don’t believe Creationist Believers in Intelligent Design would agree 🫶🏼 🌸 🫶🏼 🌸 🫶🏼

[@KenJackson_US]

Very good, @@Jesus_Resurrection_and_Life.

[@torreyance2468]

thank you for this video. my genetics teacher made things more complicated than they have to be. this video makes visualizing what happens easier.

[@lydiacole1161]

I agree completely

[@remembranceproduction4395]

Each individual's body reaction to medicine and therapy are different. a patient has to try and find the right medicine or combination for the body.

[@justindie7543]

it's not your body per se. It's which genes you happen to possess and how those genes are expressed. More DNA screening and more specifically single cell RNA seq. should be used to compare treatment options before anyone spends their life savings on it.

[@drekson23]

So how about those cancer survivors?

[@yasenkalchev7664]

@@drekson23 good point, the best point actually !

[@yasenkalchev7664]

@@drekson23 Good point, the best point actually !

[@samvrit]

@@drekson23 they survive because of either surgery or medical assistance. The body recovers on its own OR the tumor is removed surgically. There has not been a cure for cancer, yet.

[@theclassifiedmedia-j6d]

As medical students this great technology that our ancestors have not seen it before

[@getoutofmyway9025]

Nk cell is my spirit animal

[@Fradoli-edits]

It brought me more closer towards science.Please keep it up

[@Thankyou111]

I'm diagnosed with a T cell Lymphoma blood Cancer. It came up through my skin, as a 7 cm × 7 cm × 3 cm tumor, in just 6 weeks. I thought it was just my eczema going completely out of control, but no. I then changed my foods, halting the tumor in 3 days of diet change, by quitting all processed foods, quitting 6 small alcohol drinks I'd been drinking every week, and, i began using the natural hygiene diet with an added detox curve. Yes, I halted the tumor, in 3 days of diet change... I also take a high end dose of quality CO-Q10, d-3, a cheap knock off of mega mens pack heart health pack, a little bit of pure HMB, and a bit of pure creatine. After 3 days in limbo, with no processed foods, taking the supplements mentioned, I started applying all the rules of the natural hygiene diet, and I ate apples and baby greens for breakfast and lunch, meat for dinner. In my case, all of this was supposedly non GMO organic foods. The tumor instantly began to SHRINK, after 3 days of that. Within 5 days, it went from 7cm×7cm×3cm, all the way down to 5cm×5cm×2cm!! Then, I added too many ingredients. It was still shrinking, just much slower, because I tweaked the routine, a bit too complex for my tumor to shrink. AKA additional meats, garlic powder, minced onion, black pepper, green beans, and a couple other natural things, instead of just my apples and greens for breakfast and lunch, meat with a dash of salt at night.... Sometimes I use the Nicoya 3 sisters. That slight increase in complexity, was that much less helpful shrinking the tumor in my case, but helped my energy. Then, for the last 2 days, yesterday and today, I increased my apples and greens even more, and, lessened everything else, and the shrinking increased all over again! Work is ROUGH though. The natural hygiene diet demands no snacking!! Lol For over a decade I was used to eating 7-8 times per day!! Now I'm only eating 3 times, and, there are way less carbs, slight energy loss for a few reasons.... The moment I tweaked the routine, adding an assortment of carb sources etc, sure, I felt wonderful, but the tumor stopped shrinking! Now, I'm back on track, but it's difficult to work, with less energy. I need to work! So, I'm considering the carnivore diet, maybe. If I do, I can go pretty wide on my types of meats! The simplicity might cause the tumor to shrink, and I might have more energy? I highly doubt the tumor would begin growing again, provided I don't get an infection etc, in the carnivore diet. Any thoughts or experience on this anyone? Thanks in advance. My PET scan isn't until some time after Feb 10th. I may have interest in a gene therapy route. You doctors are all amazing. Thank you!

[@mxwsn]

Love that space invaders animation

[@DoubleGauss]

Fantastic graphics ! Great job Nucleus Medical Media.

[@jessicamcdonald3545]

This animation is so cool

[@Banker_blessed1111]

If animation replace all written information then human being will reach to next level because then normal person can understand so much and prohibit any disease by knowing it's symptoms and can seek best medical care

[@tmujir955]

I was amazed by the quality of the animation and the concept of immunoediting.

[@ksbalaji1287]

Thank you for this very carefully and clearly thought out video.

[@ayaafifi872]

I love the immunity so much ❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️

[@professord1522]

I really liked this video. PLEASE make one describing oncolytic immunotherapies such as T-VEC!

[@resulhackr5527]

The best animation that I have ever seen.Good job

[@rellideveraux386]

Really helped me understand how the treatment helps. Thank you.

[@NOUSSAROM]

Amazing video. Spending all efforts and great technology to make this video clear and more more easy to understand. Thank you

[@SpartaMarz94]

How is the immune response from the macrophages against the tumoral cells?

[@SukacitaYeremia]

@bietoff0728 Wth.. Is this spam?

[@Sn1per9CZE]

@bietoff0728 Another mindwashing "expert"

[@Sn1per9CZE]

@bietoff0728 Enough to know that homeopatics and herbal treatments for diseases like cancer are a dangerous game, because of which people die.

[@serogolemogole2685]

I'm not in health science but I'm enjoying this insightful presentation tremendously

[@spiridongeorgakis3860]

nice video but some of the information provided are missleading/wrong IL-2 and IFN-a are not efficient therapeutic targets because: 1) IL-2 will also promote the expansion of Tregs leading to immunosuppresion and cancer progression 2) IFN-a could promote lupus-like syptoms

[@Netbook451]

This helped a tremendous amount for my presentation. Thank you.

[@PatsyGoGo]

Great video, although background music is too loud for me to fully listen and concentrate to the subject. Especially, when English is not the native language.

[@rubbish9231]

As a smoker I needed to know this. Thanks

[@starinitalian]

!!! *PLEASE ADD THE KOREAN SUBTITLES I MADE* !!! (There are parts that are translated liberally)

[@blancosanmartin]

One of the best videos about inmune system our there.

[@lydiacole1161]

Such an amazing video!!! So much better than any textbook I’ve read

Thank you Nature

[@susanahernandez6893]

I really loved the video; and in addition, some other mechanisms of immune evasion by tomours would be the loose of the MHC 1 expression so that cell can not be detected by the lymphocyte T, but that can be helpulf for the cells NK to detected tose cells without MHC1. I'm surprised of how tomours can do the same mechanism as the Immune-privileged tissues, so they can decreased or stop the inmune response. And the inmunotherapy is like a way to potencial the functions of the T cells, so they can continue their work.

[@WallaceRoseVincent]

Animations always make it look so easy.

[@pharmacop]

Beautiful presentation. Thank you.

[@mrsdiggory3211]

Amazinggggg! Thank you for the amazing and concise and clear and fun animation

[@kitography6803]

Is there a way to get rid of the background music? Or another version without it?

[@Enran-g9q]

Can I use a short clip of this for our project promotion video? The clip would be used to illustrate how skin tumor grows and the video is for iGem competition. Thank you very much for considering our request. We look forward to hearing from you.

[@roninabil1]

Thanks for your clear explanations, Many thanks

[@nazifekonar2240]

Great video,Great explanation!

[@praptobakrie5861]

Immunology is very important..

[@johnhome5872]

Get rid of background noise!

[@wowalamoiz9489]

Hehe, here’s a like for the Space Invaders reference. Whoever made this had a sense of humor.

[@duocphamtruongtho4462]

thank you for this video

[@mgtowstanleyzoltanov9808]

Will this be available to regular humans?

[@nooninst]

what is the microscope used in this video ????

[@onyekachiobasi864]

Animations are purely effective.

[@ganbatgantulga3833]

CD8 T cell's mediated cytotoxicity scene was amazing

[@adriancastro87]

Great video about inmune response

[@savitaraina7928]

What if nk2 cells increase the reverse case

[@leot8433]

And after five year also treatment has same status. No progress while we fight for COVID but cancer patients die of lack of available treatment. Specially patients with ALK Negative and PDL1 Negative.

[@niloofarkh4779]

PERFECT

[@dramirfarhadbahreini6477]

Good animation.obstract special liy????? immunology.

[@clairepackwood53]

Totally awesome animation video. Thank you. Can we have more please?

[@sofyaleyn]

Can I use this video with Nature Video credentials mention for teaching?

[@fernandocruz7748]

Ruisantos

[@Ded-Ede]

I hope and pray.

[@devarain]

Me: WHAT THE FUCK HE TALKING ABOUT?? 2:45 Me: I see, now I understand

[@rlaaudtjq]

Many thanks for this very informative video

[@jiangyongguo]

Hello my friend, may I ask if your company needs anti-cancer drugs- (Including formula, raw materials, semi-finished products)? I am from China.

[@kevinwandago4339]

thanks so much! very helpful

[@cassiacorrea9112]

beautiful! Thank you from Brazil!

[@matthewroy7718]

THE future of cancer treatments alongside TIL. Keep discovering!

[@downstg]

Combining checkpoint inhibitors with different action is a good idea as well.

[@soyeonsoykim]

Fantastic animation!! Thank you

[@banerjeea2]

Can anyone share the link to the background music? What a fascinating musical score?

[@jorgevillarroel6046]

Me encantaría, si pueden traducirlo al español!!! Gracias

[@nimrajavednimrajaved5731]

Why the hell is music sooo loud i can't hear the lecture man

[@normanspurgeon5324]

Thank you for the video. Why do we need the imitation music in the background?

[@moutazhelal7694]

thank you for a nice video. can I ask how can I make such video. what tools did you use ?

[@darrenmarchant1720]

it may be that using tatooing to administer site specific medicine in the case of skin related issues such as melanoma will be found to reduce the effect of such medication on other parts of the body. another possible treatment for melanoma may be cauterization, which has been used by Arab communities to this day for other issues with some similarity to acupuncture. very little research is available on Arab medicine at this time.

[@jacksonhaw5514]

I am wondering is this the good cells?

[@robertaannibale1522]

me encanta esta explicación para mejorar el conocimiento y razonamiento futuros

[@vincenttelfer4206]

possible cutting off the afferent supply of blood to tumor or rogue vein

[@thefenerbahcesk4156]

So many abbreviations in this vid.

[@dystopia730]

This is great!!

[@remembranceproduction4395]

there is a different type of immunotherapy that. block the cd 47, and uses the macrophages instead of t cell to fight the cancer.

[@naikay8657]

This is so moving ❤️

[@nickkassouf]

Fantastic video here.

[@Yapity111]

Imo immunotherapy, especially the therapies focusing on killer T cells specific to the patients cancer, just may be the silver bullet we've been waiting for in the cure for cancer

[@FKGZ7]

If we can eliminate or reduce the side effects then probably yes

[@solidfuel0]

@@FKGZ7 what side effects? I thought it's better than chimo

[@FKGZ7]

@@solidfuel0 Yes but still it can kills healthy cells and in some cases patients developed an autoimmune response. We need to increase the specificity furthermore.

[@hephaestus9901]

@@FKGZ7 there will never be a cure for "cancer" cancer is a wide variety of genetic diseases.There will never be one thing that will cure all forms of cancer

[@King-Star9402]

I also think the Immune System it is the cure for cancer so what we all have to do is keep boosting the Immune System and stay healthy all the time.

[@edgaral]

Question is how tumours can use those small PDL connections and such outta nowhere, as if Tumors were intended when they're bad, feels weird to me

[@abdaddas8944]

VERY GOOD VERY USEFUL

[@rocc6596]

Does immunotherapy work for every cancer ,

[@silasenglish]

4life Research have been doing their research on this 50 years ago.

[@UdayKumar-um4nc]

Thank you for this awesome vedio ..it's very informative and easy to graspe