UK health: NHS approves groundbreaking sickle cell treatment

[@EllaBella-76]

Yay good news ..💞I know my son got tested for this ...Well done Toby .Keep premoting .

[@ProfessorCupcakeTV]

We need this in America ASAP!!! ❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤

[@cecekoe9258]

It's already available in America ask your Haematologist.

[@ProfessorCupcakeTV]

@ Thanks. I’ll look into this, as well as the cost. Peace. ✌️

[@natasha1847]

This is fantastic news!

[@dareemmanuel6079]

15k in England but possibly millions across the globe

[@chrysalis4126]

Is it £1.65 million per patient or for the 50 patients?

[@clairesloan6827]

Per patient - costs about $2million the US currently

[@fuckbankers]

50 patients a year isn't many.

[@mnbalfour1985]

Developing new treatments for sickle cell disease (SCD) might be helpful in developing new treatments for malaria, because it appears that sickle cell disease came into existence out of an attempt to evolve a resistance to malaria. It was established in 1954 that carriers of the abnormal gene are some degree protected against malaria. SCD is most prevalent in areas which have historically been associated with endemic malaria. The sickle cell trait provides a carrier with a survival advantage against malaria fatality over people with normal hemoglobin in regions where malaria is endemic. Infection with the malaria parasite affects asymptomatic carriers of the abnormal hemoglobin gene differently from patients with full SCD. Carriers (heterozygous for the gene) who catch malaria are less likely to suffer from severe symptoms than people with normal hemogolobin. SCD patients (homozygous for the gene) are similarly less likely to become infected with malaria; however once infected they are more likely to develop severe and life-threatening anemia. The impact of sickle cell anemia on malaria immunity illustrates some evolutionary trade-offs that have occurred because of endemic malaria. Although the shorter life expectancy for those with the homozygous condition would tend to disfavour the trait's survival, the trait is preserved in malaria-prone regions because of the benefits provided by the heterozygous form; an example of natural selection. Due to the adaptive advantage of the heterozygote, the disease is still prevalent, especially among people with recent ancestry in malaria-stricken areas, such as Africa, the Mediterranean, India, and the Middle East. Malaria was historically endemic to southern Europe, but it was declared eradicated in the mid-20th century, with the exception of rare sporadic cases. The malaria parasite has a complex lifecycle and spends part of it in red blood cells. There are two mechanisms which protect sickle cell carriers from malaria. One is that the parasite is hindered from growing and reproducing in a carrier's red blood cells; another is that a carrier's red cells show signs of damage when infected, and are detected and destroyed as they pass through the spleen. Sickle cell disease occurs more commonly among people whose ancestors lived in tropical and subtropical sub-Saharan regions where malaria is or was common. Where malaria is common, carrying a single sickle cell allele (trait) confers a heterozygote advantage; humans with one of the two alleles of sickle cell disease show less severe symptoms when infected with malaria. Sickle cell disease is common in some ethnic groups of central India, where the prevalence has ranged from 9.4 to 22.2% in endemic areas of Madhya Pradesh, Rajasthan, and Chhattisgarh. It is also endemic among Tharu people of Nepal and India; however, they have a sevenfold lower rate of malaria despite living in a malaria infested zone.

[@Celticsamuraiblue]

Joke Tinpot PONCE country👉🏻🏴󠁧󠁢󠁥󠁮󠁧󠁿 Joke FINISHED union 👎🏻🇬🇧 🏴󠁧󠁢󠁳󠁣󠁴󠁿☮️🇪🇺

[@TM-rk5dj]

Yay 🎉

[@kevinwilliams1768]

great news .

[@ErsagunMustafa]

i used to think being magnetic was just about looks or confidence, but i couldn’t have been more wrong. i read this book called Vibrations of Manifestation by Alex Lane, and it totally changed my perspective. it breaks down the energy and mindset behind true attraction in a way that just makes sense. once i started applying what it taught, i noticed people reacting to me differently almost instantly. it’s seriously worth a read.

[@momurda6]

It's amazing that sickle cell is being treated, but there are many other red cell disorders. How about also shining some light on those as well.

[@dareemmanuel6079]

so many others that you can't even name one off the top your head that's caused more harm for centuries

[@fuckbankers]

This will help with all research

[@jujutrini8412]

This is good news for other red blood cell disorders. It means that new treatments are being discovered. It doesn’t end here!

[@guff9567]

So treatment of foreigners prioritised?

[@jujutrini8412]

They’re not going to be treating foreigners. The fifty people will be British people.

[@guff9567]

@jujutrini8412 with a foreign diseases caused by inbreeding? Not possible

[@SebsWorld]

DONALD TRUMP FOR 2028!❤

[@Bungle-UK]

These people always love to play the victim card.

[@luciavalente1002]

What?

[@CarterSimon777]

🤡🤡🤡

[@fuckbankers]

Weirdo

[@lookingatdaisies9901]

This may take the spot for the most stupid comment of 2025. Calling the sufferers of a disease 'playing the victim card", We're accusing victims now?

[@CarterSimon777]

@@Bungle-UK 🤡

[@CLINTONCromwell-t8v]

one night i was scrolling through my phone, feeling like i’d never figure out why some people just seem so magnetic. then i came across this book, Vibrations of Manifestation by Alex Lane, and something about it caught my attention. reading it was like turning on a light in a dark room. it’s not about pretending to be someone you’re not; it’s about unlocking the energy you already have. trust me, this book is worth every page

[@RaeleneMorton]

i remember feeling like i was always the one fading into the background while others stood out effortlessly. it was frustrating and made me doubt myself a lot. then i came across this book, Vibrations of Manifestation by Alex Lane, and it showed me things i’d never even considered. it’s not just a self-help book; it’s like a guide to understanding your own energy and using it to connect with people. if you’ve ever felt like you’re not seen, this book might change everything.

[@LOWELLElliott-n9r]

i remember this one time i felt like no matter what i did, people just didn’t notice me. i tried everything-confidence boosters, social tips, you name it-but nothing seemed to work. then i found this book, Vibrations of Manifestation by Alex Lane, and it completely shifted how i saw myself. it’s not just about being noticed; it’s about understanding the energy you project. honestly, this book made all the difference for me. if you’ve ever felt invisible, you need to read it.

[@MartyMunn]

i thought manifestation was just about thinking positive and hoping for the best. but after reading Vibrations of Manifestation by Alex Lane, i realized i was missing the most important part-the energy i was actually putting out. the book explains exactly why some people seem to attract everything effortlessly while others struggle no matter how hard they try. once i adjusted my own frequency, things just started falling into place.

[@SherylBurton-v8w]

there was a time when i kept wondering why some people seemed to naturally draw others in while i was just…there. no matter what i tried, i couldn’t figure out how they did it. then someone mentioned the book Vibrations of Manifestation by Alex Lane, and i decided to check it out. the way it explains how your aura affects everything around you? it blew me away. it’s like having a secret code to unlock your magnetic energy. this book is a game-changer.

[@EVANCameron-g6d]

i always felt like i was stuck in the same cycle-watching other people manifest their dream lives while i kept getting the short end of the stick. no matter how much i tried, nothing seemed to work. then i picked up Vibrations of Manifestation by Alex Lane, and something clicked. it made me realize i had been doing everything backwards. after a few weeks of applying what’s inside, things started changing fast. my confidence, my money, even the people around me. it’s honestly crazy.

[@FLETCHERVernon-s7e]

i used to think success was all about grinding harder, pushing through, and hoping things would change. but no matter what i did, i kept running into the same roadblocks. then i saw a few people talking about Vibrations of Manifestation by Alex Lane, so i gave it a shot. i wasn’t expecting much, but the way it explains energy and alignment completely flipped my perspective. it wasn’t about working harder, it was about shifting my energy first. everything started flowing after that.

[@KubilayBerker]

i remember this one time i felt like no matter what i did, people just didn’t notice me. i tried everything-confidence boosters, social tips, you name it-but nothing seemed to work. then i found this book, Vibrations of Manifestation by Alex Lane, and it completely shifted how i saw myself. it’s not just about being noticed; it’s about understanding the energy you project. honestly, this book made all the difference for me. if you’ve ever felt invisible, you need to read it.

[@DICKGatlin]

i remember feeling like i was always the one fading into the background while others stood out effortlessly. it was frustrating and made me doubt myself a lot. then i came across this book, Vibrations of Manifestation by Alex Lane, and it showed me things i’d never even considered. it’s not just a self-help book; it’s like a guide to understanding your own energy and using it to connect with people. if you’ve ever felt like you’re not seen, this book might change everything.

[@BRETHendrick]

one night i was scrolling through my phone, feeling like i’d never figure out why some people just seem so magnetic. then i came across this book, Vibrations of Manifestation by Alex Lane, and something about it caught my attention. reading it was like turning on a light in a dark room. it’s not about pretending to be someone you’re not; it’s about unlocking the energy you already have. trust me, this book is worth every page

[@DilekAbdullah-q7x]

there was a time when i kept wondering why some people seemed to naturally draw others in while i was just…there. no matter what i tried, i couldn’t figure out how they did it. then someone mentioned the book Vibrations of Manifestation by Alex Lane, and i decided to check it out. the way it explains how your aura affects everything around you? it blew me away. it’s like having a secret code to unlock your magnetic energy. this book is a game-changer.

[@AydinAhmet-i9v]

i used to think success was all about grinding harder, pushing through, and hoping things would change. but no matter what i did, i kept running into the same roadblocks. then i saw a few people talking about Vibrations of Manifestation by Alex Lane, so i gave it a shot. i wasn’t expecting much, but the way it explains energy and alignment completely flipped my perspective. it wasn’t about working harder, it was about shifting my energy first. everything started flowing after that.

[@KarlBurleson]

i always felt like i was stuck in the same cycle-watching other people manifest their dream lives while i kept getting the short end of the stick. no matter how much i tried, nothing seemed to work. then i picked up Vibrations of Manifestation by Alex Lane, and something clicked. it made me realize i had been doing everything backwards. after a few weeks of applying what’s inside, things started changing fast. my confidence, my money, even the people around me. it’s honestly crazy.

[@CharisseCaldera]

i used to think being magnetic was just about looks or confidence, but i couldn’t have been more wrong. i read this book called Vibrations of Manifestation by Alex Lane, and it totally changed my perspective. it breaks down the energy and mindset behind true attraction in a way that just makes sense. once i started applying what it taught, i noticed people reacting to me differently almost instantly. it’s seriously worth a read.

[@ArielleSheehan-h7n]

i thought manifestation was just about thinking positive and hoping for the best. but after reading Vibrations of Manifestation by Alex Lane, i realized i was missing the most important part-the energy i was actually putting out. the book explains exactly why some people seem to attract everything effortlessly while others struggle no matter how hard they try. once i adjusted my own frequency, things just started falling into place.