Amitriptyline

Amitriptyline was approved over half a century ago as an antidepressant and still remains popular today. Interestingly amitriptyline provides a similar degree of relief from depression as more recent additions to our armamentarium. Selecting among the various options involves considering other circumstances: medical issues, patient preference and side effect profile.
Over the years, the indications for amitriptyline expanded far beyond depression and often without either formal study or specific FDA authorization. Among the conditions routinely treated with amitriptyline are fibromyalgia, chronic fatigue, diabetic neuropathy, pain lingering after shingles, insomnia and low back pain. Amitriptyline ranks among the least expensive options to prevent migraine headache and may even remedy chronic itchiness.
A major issue with amitriptyline involves tiredness or fatigue. For this reason most doctors recommend taking the medicine just before retiring for the evening. In fact many physicians prescribe low doses to treat insomnia rather than larger amounts necessary to combat depression.
Among the many undesirable side effects of amitriptyline are dry mouth, blurred vision, constipation, weight gain, difficulty urinating and erectile dysfunction. Problems concentrating and the potential for cardiovascular issues pose further concerns. Common to all antidepressants, the FDA mandates a warning of increased suicidal thoughts and behaviors especially among those less than age 24.
Amitriptyline interacts with a significant list of other drugs. Special cautions concern triptans used to treat acute migraine attacks, Lyrica, gabapentin, tramadol and anti-psychotics now commonly employed in treating schizophrenia, mania of bipolar disorder and agitation associated with autism in children. MAO inhibitors must not be used within 2 weeks of amitriptyline. Overlap with the popular SSRIs and SNRIs such as Prozac, Celexa, Lexapro and Zoloft may risk a nasty condition known as the serotonin syndrome. Consuming alcohol while taking amitriptyline poses further risks.
After a course of therapy the dose must be gradually tapered rather than abruptly discontinued. Among the antidepressants, overdose of amitriptyline poses the greatest risk of death.
When used appropriately, amitriptyline continues to offer significant relief for a number of conditions of uncertain origin. Unfortunately the scientific underpinnings of how we select our therapies lags far behind our confidence level and ability to write prescriptions.

[@StrongEnoughMusic1]

RIP Ken....you were my favorite educator on KZbin... you helped so many😢

[@lazmotron]

Did this s You Tube channel Dr. die?

[@lazmotron]

What a shame that the good Dr is gone. I came across his channel to late. Good bless him!

[@blairkerr7911]

Dr. Ken, an amazing source of difficult medical information. No teleprompter just straight off the cuff.Thank you sir, R.I.P.😢

[@jamesmartin8232]

R.I.P. Dr. Ken. 🙏 I've learned so much from you regarding the medications I've been prescribed. Thank you sir.

[@ATerriblepurpose]

I love the speed of information. This single video has done what others try to do in an entire playlist.

[@Nina_Olivia]

Agreed. Excellent, efficient delivery.

[@Sushant_saurabh]

Tbh yes😂

[@Sri_369]

It's a life saver ,wonder drug for me. It worked for multiple symptoms like insomnia, depression, anxiety, migraines,energy booster, muscle pains,ibs etc Side effect I faced was dry mouth,weight gain,fatigue, constipation

[@jcbanbury]

@kingwoods Woods oh they are no scam! I used to think the same and laughed at anyone who says they have anxiety. I know better now.

[@jcbanbury]

@kingwoods Woods pills won't help your root cause.

[@Sri_369]

@kingwoods Woods Good move 👍

[@feliciacampagnone1225]

I take amitryptoline for headaches to cure them and i have severe constipation and constantly have to use edemas and laxatives and stool softeners what do i do??

[@garysimone4977]

@@Sri_369 it worked for your insomia ??? How bad was your insomia and what dose ya at. Tks

[@suzannedocker8908]

Thankyou for your help I take 10 mg for chronic pain from fibromyalgia I take. Up to 2 3 aday

[@karenvanessan.2000]

This drug was the only thing that gave me my life back after being diagnosed with vestibular migraine. It didn't help with my headaches but it got rid of my constant dizziness and rocking sensation.

[@sameeeha1]

I have been prescribed for anxiety and yes I suffered from vestibular neuritis fr almost a year. It would be a great help for me if u tell ur experience in taking this medicine in detail. As u mentioned abt dizziness. How was it taking it. I'm scared to start this medication coz of huge side effects mentioned by the other people in the comments section.

[@michaels999]

Curious to know if you are still taking this medication and does it still help you?

[@OleSkaaren]

How is it now?

[@SunshineDawn7]

@@sameeeha1 It has helped me with depression, anxiety, headaches, sleep. It does make me gain about 20 lbs but when i go off it i loose the 20 lbs without trying. Hope you are doing well 👍

[@nogelastofile8146]

​@@michaels999😮

[@LarryKippings]

I’ve taken 10mg for about 8 years. I had daily tension headaches, and sleeping issues. This has helped a lot with both. But I do have vivid nightmares as soon as I go to sleep, wake up after 10 minutes, then sleep through the whole night fine. Weird. I’m sure when I try to stop, there will be withdrawal symptoms. Best take medical advice before stopping.

[@kevcat8655]

Do you not build up a tolerance to it? Is 10mg still as effective after 10 years as it was on day one for you?

[@LarryKippings]

@@kevcat8655 I’m still on 10mg, and still no headaches. I haven’t had to increase the dose at all in 8 years. I may start to reduce the dose soon, and it will be interesting to see if the headaches return.......

[@brock3411]

Here's just a friendly suggestion - If it helps for your main symptoms, then don't stop taking it ever. You must weigh your pro's and con's, you know? Just my opinion, that's all

[@LarryKippings]

@@brock3411 Thankfully the headaches didn’t return after I stopped taking it, but I did have to reduce dose slowly & it took 6 months to get through the withdrawal symptoms. Worse WS was not being able to sleep, it’s almost as if my brain forgot how to go into deep sleep. Thankfully many others have experienced the same problem, and managed to start sleeping again after 6 months to a year. It’s hard to stop, and sometimes feels impossible. But it can be done!

[@susanf1566]

I've been on 10mg for 2 months now for headaches. I was told to move to 20 MG it made me a crazy person after two weeks. I feel more normal on 10mg. I guess I'm sensitive to it. I guess I'll see how things go in the long-term.

[@JohnBedson]

Ken: Your videos are fantastic. Thank you.

[@nicolevonw8101]

He is great! Like a book! ☺️

[@Sri_369]

This doctor is awesome..🙂.very informative👏

[@Kas873]

This guy is amazing. I learned so much! I have been taking Sertraline (50mg/day in morning) since last summer, and started Amitriptyline (25mg/day at night) about a week ago. My sleep has been great, and NO migraine headaches!!! Which is why it was prescribed. I am definitely lethargic the next day, but it isn't bad. I already have low blood pressure to begin with, and it has exacerbated that, but I'm already used to dealing with it, so I can be prepared. I no longer have allergies either! So for me, so far, the side effects haven't deterred me. I remember I did have some side effects when I first began Zoloft, but they eventually went away. So I am thinking they will eventually go away from Amitriptyline too. It has been a game changer for me!

[@Lovelykitten78787]

I was also prescribed Sertraline. Was wondering if Amitriptyline is better. What would you say?

[@Redspittingcobra]

If you have anxiety and poor sleep take amitriptyline. Zoloft doesn't work in many ways like amitriptyline does.

[@andykanani5671]

As an antidepressant medication I’ve had no success with anything and I am interested in trying magic 🍄 but I work graveyard shifts and this medication has helped me get some more sleep 😴 during the day.

[@joannechisholm4501]

Amitriptyline was a god send for me after getting migraine im going through Peri Manapause my mood is all over and getting headaches and migraine on a daily basis

[@chickstar69duplicity35]

Peri "'man'opause" 😂😂😂

[@andrewmunz1639]

Amitriptyline has activated a migraine, every 2 days, i now deal with migraines feverview, i pinch apiece of leaf eveyday, it is bitter but i haven't had one in a year.

[@SteveSnowman]

Dr. Ken Landow appears to have it all figured out. Lots of wisdom too. Go-to for my new tries on meds.

[@xshanayasharmax5949]

i got prescribed this for post concussion syndrome and it has helped me a lot. I went from 3 headaches a day to 1 every 2/3 days. However, it made me very sleepy during the day but coffee helped 😂 Make sure you have this before bed because you will become very drowsy if you take it during the day. My sleep has also improved a lot! 8 hours to 10 hours.

[@theorysmasher7022]

I love your reviews. Amitriptyline was the only antidepressant which worked for me. I take it also for nerve pain which is why I got it prescribed.

[@Cryptosavage.]

Did it help with nerve pain.

[@lisadunn7908]

@@Cryptosavage. ive just gone back on it after a 6 year break i have trigeminal neuralgia a month back on these aready feel the diffrence in pain levels and sleep helping me with my nerve pain on 50mg at moment can go up if i need to

[@mikesnyder7961]

Last year I developed panic attacks and insomnia for the first time in my life (I was 35). It became so bad, I would get a panic attack every time I would lie down. Nothing worked; zoplicone, Zoloft, lexapro, mirtazapine, lorazepam, clonazepam, trazadone, seroquel, olanzapine, Effexor, then along came Amitriptyline. Anxiety gone. Panic attacks gone. Insomnia gone. It was the only thing that worked. I take 30mgs at night, and will probably do so long term. If you are suffering from anxiety and insomnia, I would say at least look into Amitriptyline. A lot of doctors were hesitant to prescribe it because of the side effect profile; I met an psychiatrist at the hospital and she said “sure, let’s try it. It’s proven effective…” I can’t thank her enough. She saved my life

[@peguiiiin]

can for anxiety..i anxiety 37 years?

[@chrisarmond6723]

how are you doing now?

[@mikesnyder7961]

@@chrisarmond6723 good. Been off all psychiatric drugs for about 6 months now. Weaned off super slow (drop 5 mgs every 8 days). If I ever have another episode, I at least know which medication to turn to!

[@amyring3865]

I've tried pretty much all the antidepressants too and Amitryptilne is the only one that helps me too. Could've saved alot of time and money if they prescribed it to me from the start

[@Tomi_1808]

I’m going through severe anxiety and it’s affecting my life so bad because it’s almost impossible for me to communicate. My dr just prescribed amitriptyline for me last week and I’ve been on it for a week and 2 days. Hopefully it helps me to live anxiety free life. I can’t just deal with having to constantly feel anxious and stressed!!!

[@Texassmith9095]

I have been using this at 100mg at night for sleep since the late 90s for sleep. Side effects are easy for me to get use to and my sleep quality is very good.

[@karamalawad6816]

هل يسبب الدواء وخز في الجسم

[@azmagaref]

Goodness, that's a while! I started early January this year 25mg, I'm at 45 mg yet to go up. I'm not finding a huge relief yet from depression, about 95 percent of anxiety relief! The tiredness is a continuous issue as well.

[@grapjesmettomentim3144]

What are your side effects? I have been taking it for 4 years (started with 25 then 50mg) apart from a dry mouth nothing really. Now my GP wants to try and stop, im on half dosage and fucks with my sleep massivly. I feel like the side effects of barely sleeping are way more dangerous than those of amitrptylin

[@Texassmith9095]

@grapjesmettomentim3144 dry mouth is my only side effect. Doctors don't like you to be on it for a long time but just be firm about staying on it.

[@grapjesmettomentim3144]

@@Texassmith9095 Thanks for the fast reaction. I never, and still not am, a fan of taking drugs. But if it continues to be this bad im going to opt in for staying on them.

[@immortal4942]

this drug saved my life. I have had lifetime prostatitis since I was 18

[@IBSBrad]

How did this help with prostatitis?? Like can you explain what a couple of your symptoms were??

[@matchpoint14]

@@IBSBrad he probably had pain in the prostate and that controlled the pain down there. I used to get pain down there some and I would go sit on a heating pad and that would take it away really fast.

[@matchpoint14]

@@IBSBrad just curios do you have IBS? If so I had it for years and years I healed mine with going off all junk food and eating a oatmeal daily and a smoothie with 3 or 4 raw super veggies like spinach, kale, collards, I also added a small serving of ground beef each day because it has glutamine which heals the gut..fast

[@jenniferjordan7393]

I can’t live without this. Saved my life. I couldn’t tolerate SSRIs. Without this drug (25mg) I am dealing with non stop panic and depression. I also have Crohn’s disease and IBS. I actually don’t think I could live in my body without it.

[@karliann1]

Me too. Helps my mental and physical ailments

[@webmasterepm]

Do u also hv muscle pain

[@JJs2121]

hi. How is it going now are you still using this

[@karliann1]

@@JJs2121 I am and have been for a very long time and it helps my sleep pain level and mood. Works better for me personally than the SSRI or snri

[@cisrot]

Thank you so much, I was prescribed this recently to help me with my migraines.. though I’m also diagnosed with anxiety (OCD oriented) and depression etc. I’ve taken it for one day and it knocked me right out haha! I was super anxious to start this because I really didn’t know much about this medication before this video. I’m still young (24) so I’m not too worried about the side effects that may cause issues for older people. It’s always interesting to know the pros and cons of medications. I’m looking forward to seeing the effects since I’ve had to take codeine for a long while to help with my migraines and headaches. Hopefully taking this will help me get off taking them too!

[@MXedits_1]

Lol you f**** your life. Review 6 months later? I assume you're on Pregabalin now? :)

[@mikeythearchangel]

Hi :) any chance of a follow up? Did it work for You?

[@allimimi]

RIP Dr. Landow 🕊Awesome doctor!

[@7inchdestroyer959]

youre a hottie

[@BraniG-psyc03]

He died?❤️

[@7inchdestroyer959]

@@BraniG-psyc03 Yea :(

[@coolkatz9012]

Failed cervical 2 level surgery still chronic headaches nerve pain this med has worked wonders for me thank god.

[@marielamengozzi8428]

I take 25 mg for IBS, and thanks to this medicine because it works really well on my intestine, fantastic!

[@junaid8707]

With side effects

[@marielamengozzi8428]

Junaid Farooq all medicine have side effects, and the decision to take them is a based on benefit vs side effects....always!

[@somneang87time29]

Mariela Mengozzi how long do you use it?

[@marielamengozzi8428]

Somneang Time87 ciao! I started around 2007, I have tried to stop it in 2018 but the symptoms were coming back. So I suppose “forever”. My IBS is severe and the 25mg is a very low dose. I also have a FODMAP diet approach because the medicine alone is not sufficient. I have found a good balance between diet and medicine. I do not eat diary products at all, I am genetically intollerant.

[@somneang87time29]

Mariela Mengozzi Thank you for reply I have IBS too since last year And I try to cold turkey but my symptom come back Maybe I will use it forever too Do you use it before bed time?

[@HS-yk9he]

I take 20 mg at night for IBS which is from my anxiety. My skin rash is gone also. It works very well for me. I just have to control my appetite.

[@karamalawad6816]

هل يسبب الدواء وخز في الجسم

[@Yui714]

I've been using/testing Amitriptyline for about 6 years now. Just one small dose (20mg) before bed to treat chronic foot and ankle pain. Its paired with Gabapentin for adequate pain relief and both are essential for results. I find that 20mg before bed will "zombify" me the entire next day. What that means is that I'll never feel fully awake or clear-minded. It makes me a very boring person socially with nothing to say. Just puts me on auto-pilot. For this reason, I don't take the Amitriptyline on nights before days off because I want to feel alive on my free days. It works. Most people take higher doses to treat an entirely different condition (depression). I think my brain would explode at those higher doses. Some days I feel like I blew up my brain with just 20mg the night before. BUT everyone is different so maybe that's just me. Either way, I've tested these things out personally and this is the data I've collected based on my experience over the years. I'm 32 years old now.

[@DLJoLo]

Has it affected your weight?

[@butwhytho4858]

I’ve been fighting some mystery nerve and autoimmune illness for about 10 yrs. A neurologist decided to try this last week as a last ditch effort. Took it for the first time last night. This morning I woke up ok-ish. I expected grogginess after trying gabapentin (sp?) and other drugs, but after being awake a while, I am getting dizzy and when I lay down there’s a throbbing head ache. What’s sad is that my neck, face and shoulders don’t hurt as much. There’s a numbness there and it feels so nice… It’s so sad when you have to choose between life’s pain and sideffects. I have 2 young kids. I can push through pain by now but it’s hard to push through side effects.

[@ohnoes7032]

I hope the side-effects have come down a bit, and the pain-relief has remained. Thats how it worked for me, i was very skeptical at first.

[@ALT-vz3jn]

Are you still taking it now? My Dr said it takes a month to see the full benefit and you have to increase slowly.

[@Texas1987]

Use CBD for pain and no side effects

[@user-dd1bb4tw4r]

I've been prescribed this for sleep since rehab. I've always had trouble sleeping i used to take 50mg but now take 25mg. I sleep great since taking this medicine.

[@_Significant-Neat_]

Why did you lower the dose?

[@yamiletvasquez8031]

Are you still taking it? Do you plan to ever come off it?

[@user-dd1bb4tw4r]

@@yamiletvasquez8031 I quit taking it because I would sleep too much and be drowsy for work I drive semi trucks for a living so I need to be awake and alert. My shifts run 10-14 hours a day 5-6 days a week if you have an 8 n skate job then it's a reliable option for sleep.

[@yamiletvasquez8031]

@@user-dd1bb4tw4r so now that you've stop, do you still sleep well now? My doctor prescribed me the pills but im so afraid to take it after reading all the side effects and then reading that you can't just stop when you want, you gotta be tapered off. I have insomnia caused by my anxiety, i wanna take it to sleep well but im afraid.

[@user-dd1bb4tw4r]

@@yamiletvasquez8031 no but I've always been a light sleeper. They say you can't just quit taking it bc it's an anti depressant but for sleep it's a very low dosage. It's one of the oldest anti depressants prescribed and rarely prescribed for anything other than sleep a high dosage is 150mg per pill at low dosage like 10-25mg is does help for sleep. They quit prescribing it in high dosages bc it WILL BE FATAL when taking the whole bottle. You will be ok and you will sleep well on it just make sure to take it early and get to bed at least 10-12 hours before your next shift :)

[@soup_please]

You really have a knack for talking about really boring stuff on the most engaging way possible

[@EdwardRhoads]

Rest in Peace. Dr Robert Kenneth Landow. Passed away on 3-11-22 at age 73.

[@nopants4259]

can't sleep , always itchy , mild depression and panic attacks , hope it works. seems ideal for me.

[@jonasf1706]

Same. Have you taken it yet?

[@JohnDoe-gk4kn]

I sleep like a rock and the next day I hit the gym like a champion. Best sleep of my life. I'm calmer , less aggressive, just well balanced when I take 50mg daily. When I'm off the beds I sleep 4to 5 hrs a night, Becoming very aggressive, Gain weight, all around moody

[@evelyny7037]

FDA took it off the market, but left the generic. It’s one of the hardest drugs to get off. Just fyi.

[@sofalvarez]

Really? I just got my prescription… one of my main concerns are the withdrawal effects but my therapist told me it is not that hard to get off 😰

[@evelyny7037]

I would encourage you to do your own research. Because we’re now to time and history when it’s very difficult to get to the truth of something unless you’re willing to put a little work into it. I no longer take someone’s word for something, as I have seen the danger of that for over 30 years. Dr. Kelly Brogan has some great KZbin and great information on this subject.

[@taemac10]

​@@sofalvarez It's still on the market for sure. It's very strong

[@T_Tongg]

Wow... what an amazing amount of information. Thank you kindly Sir.

[@zotar9279]

This drug just makes me want to sleep all day long...

[@wokeindividual7031]

Because you probably need to have dreams and untangle. Let go of your past.

[@waleedalsiraji6262]

Same here...

[@DesertFoxz]

Take it at night before bed

[@marielamengozzi8428]

The sleepy effect depend on the dosage and a very important key point: NO ALCHOOL ASSOCIATED, because the sleepy effect goes up!!

[@saigenrose1032]

I take 300mg once at night it knocks me out but causes constipation. I wish there was another med that would work the same.

[@ztuzar163]

I got this for shingels pain, but the dreams was the biggest positive ! I will never give them up !!

[@TheFabricTeapot1]

I was put on this tablet (100mg per day) about 25 years ago. It was the worst thing I've ever experienced so came off of it. About 8 months ago I started to experience a lot of pain due to nerve damage. I was prescribed this tablet again as it apparently helps with nerve pain. (I had forgotten I was previously on it) this time, however, I was prescribed just 10mg per day. Oh boy! what a game-changer for me. I have the best sleep ever although quite vivid dreams but not horror. It helps with my anxiety, helps me to handle it better. It's gotten rid of my nerve pain (that took about 2 plus months) and it's helped me to drop 15lbs in weight so far. I'm not looking to come off of this medication anytime soon. Whatever it's doing, it's benefiting me.

[@1x1HealthyEnergybyAndrew]

How did you lose weight? I like your attitude and hope to make a change.

[@EC-yd9yv]

What is the manufacturer on med preferred?

[@tfoxen7518]

Prescribed 10mg for nocturnal leg cramps. Did not reduce muscle contractures or neuralgia. (I have residual nerve damage from Guillain-Barre syndrome.) This med caused severe dizziness when standing from squatting while working.

[@jayton580]

I was taking 50 then bump me up to 100mg I was the happiest person walking around just hated the morning grogginess.

[@trishpillsbury]

I have vestibular migraine and cyclic vomiting and have been on for several months, seems to be working! My sleep is great

[@alyxisfeltus6220]

Does it help with the vertigo and what does are you on?

[@32starsandsugar]

This channel is amazing!! Thank you!

[@mz.fabulous17]

I was prescribed this for nerve pain. I took this for 3 nights and gave me vivid nightmares and anxiety. Trash it.

[@dee6159]

What exactly were you prescribed this for?

[@kojack7425]

Your worst nightmares I with you.. crazy drug

[@christiansage8079]

I remember being g prescribed this and caused me to cry uncontrollably. I just remember feeling super depressed

[@SouthernSoftie]

I have it prescribed for neuropathy, however I take it just periodically to get a good sleep.

[@francesa9776]

I gained almost 20 pounds. Sleep and eat that's all it made me do. Yes it did help my tension headaches but at a big cost.

[@garysimone4977]

did this med help you sleep how long before bed you take it ,,, how many mg ya on,,, doc told me it takes 2 weeks before it kicks for sleep, you here that,,,i am not sure how long i will stay on it,,, started me on 100 m,g,,, been on it 8 days , not so sure about this med

[@user-yo9xs8tl5o]

Funnily those were some of the reasons I was taking it. Sleep and appetite disorders. This medicine seems to have a range of effects.

[@ryanacehigh]

What dose?

[@matchpoint14]

I took half a 75 mg tablet for migraines and back and neck pain. I felt the next day. My headaches were 80 percent gone and so was the pain. I am shocked. I was very tired though. I think I will take half of the other half and stop for 5 day and then take them again for 2 days. So 2 days on and 5 days off. At least I will get 2 days of some relief, if it keeps working like that.

[@wendybell9007]

Really helpful information thank you

[@emward6858]

I take 10mg for fibromyalgia. But I’d rather put up with the pain than deal with the irritableness and increased hunger. Years ago when I was 14 I was taking 25mg a day for depression that went up to 50mg a day aged 15. Years and years ago I took a OD of it and I had confusion and hallucinations etc . Never ever take any OD , always talk about your feelings and problems

[@michelenichele294]

This tardive dyskinesia, which I mention below happened to me after Bering treated with amitriptyline for approx. 9 months. Now I’ll have this condition the rest of my life and will have to be treated for it. And Landaw, you’re not warning the viewer about this. What else are you leaving out of your presentations that Walgreens includes in their patient printout? I thought you were supposed to be a more thorough source’? 🧐

[@sheshlane]

Michele so sorry to hear this. I took this medicine years ago. I'm thinking I was taking only 25mg. I had to stop soon due to feelings of restlessness, unease. I couldn't sit still. Felt awful and started drinking alot of water to flush the drug out as soon as possible. That's been over 20 years ago. I'll never forget how horrible I felt on it. It was prescribed for clinical depression.

[@EC-yd9yv]

Michele what dose pls?!

[@sammylagat1559]

I was prescribed this drug, been taking it for a month and a half now I've experienced weight gain and skin rashes

[@lyndayates7533]

How much weight gain please?

[@lyndayates7533]

@@lisad4854 I wouldn't. Watch "The History of Psychiatry" or listen to Dr Peter Breggin about the harm these drugs cause. And when you Google the drug be sure not to look under sponsored by or any other way psych drugs are promoted. Look under horror stories for what actual ppl have been and gone through. It's not good. I think our government wants us on these drugs. I don't like it but you have to make your own choice. I can tell you I am not depressed but each and every single visit to the Dr I am offered a psych drug. I'm so tired of it. I told my Dr I will never take them and he still offers them. I have lists.... Also these drugs are re-labeled black box. So many names. Be careful and vigilant because even if they say these drugs are not addictive they usually are and they often cause brain damage. You have to study deep to find the true meaning of these drugs. Now you tell me who's crazy because I could never hurt another with these drugs. I take Xanax. For 30 years now. I wish I'd never started but when I was young we weren't told or had any real way of knowing the side effects. At one time I was given 6 Xanax 1 mg and 600 mgs seroquel for sleep. I lost years of my life. My health and my children seeing me in such a drunken state daily. A pancreas attack. GB removal. My health has been ruined by these drugs. Been researching for so many years. I advocate against these drugs but I leave the choice to others except babies, children and teenagers. These groups are all targeted.

[@lyndayates7533]

@@lisad4854 never taken an antidepressant other than a day or 2 but with seroquel I gained 123 lbs.

[@ebingo10]

I enjoyed watching your video. I am a medical intern preparing for a presentation today. Thank you so much!!

[@gemz9284]

First guy I come to when I learn about a medicine

[@TheThe13used]

been taking for sleep for a few days now and i sleep well and feel way better during the day yay

[@TheQueen-yb3xp]

Thanks God we have you Dr. You are Amazing ❤

[@JourneeInJanuary]

This was very informative....thank you so much for posting

[@wellingtonmiddleton3739]

Thank you, thank you. Very informative as you break it down so easily to understand.

[@kimlec3592]

Heart rhythm abnormalities, tachycardia, stroke, weight gain.. the list of side effects is quite scary. Get yourself a pill cutter & take as little as you can get by with.

[@sharonbice7490]

It worked great for my pain, helped me sleep, until my doctor added DuLoxetine to it. Then winging off both the right way, I ended up in the hospital, thought I was having a stroke.

[@BimmerWon]

Oh God. I hope these side effects are rare. I’m starting 10 mg today and I’m worried.

[@user-yo9xs8tl5o]

Dont worry. All you will really feel is relaxed and sleepy 2 hours after taking it. Maybe a little extra drowsy in the morning. Bad side effects are very unlikely on low doses. I have been on 30mg and had no bad side effects. Only minor ones like thirst and dry mouth.

[@BimmerWon]

@@user-yo9xs8tl5o sounds good. I hope this is the case for me too.

[@shockwave6416]

@@user-yo9xs8tl5o interesting. I'm looking at taking this for insomnia.

[@sergiovargas8676]

How have you felt taking it? I was prescribed 10mg 2 weeks ago I have been scared to take it ...tonight I will try one can you tell me how you felt ?

[@shockwave6416]

@@sergiovargas8676 I didn't take mine lol! I have it for insomnia

[@dorothybeveridge3133]

My doctor have given me this but , I’m on venlafaxine & I’m frightened to take it together .

[@ASMR-XI-ZUI]

I have cvs (cyclical vomiting syndrome) the gastroenterology doctor hasnt prescribed me it yet. Currently take quetiapine xl and venlafaxine xl for schizoeffective disorder. Is amitriptyline available as xl (extended release) version.

[@leonietrezise9198]

25mg morning and night. Sleep at night better. 25years Fibromyalgia survivor. 💯🇦🇺

[@ginnyleedays]

I appreciate you I always come to you with any questions I have you help so much

[@equinoxeparabellum6776]

It saved my life. I was in so much pain until I found this 25mg.

[@666Victor777]

You need to take it regularly to get rid of the pain? Or it cured the pain?

[@equinoxeparabellum6776]

@@666Victor777 that's a good question, I take it once per day. It took about a week to start working. It blocks nerve pain. I do not know if the pain will come back once I stop taking it but the pain I had was so severe that I couldn't sleep at all. It was a living nightmare. I have a herniated disc so am hoping as that settles down the pain will subside. 🙏

[@666Victor777]

@@equinoxeparabellum6776 thanks for sharing your experience! Glad it worked, its a lifesaver! Take care.

[@papabear2515]

Me too. But I’ve had to increase to 50mg after 3 years as pain started resurface. Then, 2 years later, had to go to 75 mg as pain returned. Now, I am still on 75 mg and it’s not working like it did before. Going to go a couple more weeks on 75 mg and if it’s still not working like I need it to -and as it used to - I will be contacting my doctor to see what else can I take. The amazing thing for me was that when I first started taking it - it truly changed my life! 100% of pain gone! It was hard to believe and there are no words for the gratitude I felt. I had my life back after having spent 12 years in pain, with numbness/electrical like sensations in my hands and legs. Hoping I can find something that will work if this 75 mg dosage doesn’t work as it did.

[@equinoxeparabellum6776]

@@papabear2515 12 years horrendous, so sorry as that's a long time. Assume like me they have never got close to what's causing your pain? I have a severe herniated disc at L2L3 and they suspect it could be the cause but won't operate to confirm. I get electric shocks, stabbing and burning in my groin area 😥 man area too. It's horrendous. I have heard that severe stress can bring this on. I have a history of PTSD. Have you any idea what could be causing your symptoms?

[@bendory]

He appears to just be reading out the product label?

[@Heliweli]

I've come off it 2 days ago, I was percribed 10mg for 2 bulging disc. I now have pulsating tinnitus, so I'm hoping it will stop now I'm off it, don't take it!

[@apollonia6656]

Was given because of my MS. I ended up with so many missing beats that I stopped taking it. My doctor did not believe me. My body says "Do not take these pills" and my body knows best.

[@michaelbennett8981]

My doctor did the same. I was gonna start taking it today, but I'm not so sure anymore. Good luck!

[@onerider808]

Scared the heck out of me with the adverse symptoms. Seems like the disadvantages outweigh potential benefits...for me. It did help with the crushing headaches I got from whiplash, though. I hope I can be off it soon; it has no place in an athlete’s life (at least this one).

[@0x-rf7yk]

Can you please elaborate? I am an athlete and considering this prescription. It would be very helpful to know more about your experience. Thank you!

[@nebiyu7001]

What about the hell pit withdrawal symptoms.that lasts forever

[@equinoxeparabellum6776]

I have heard amitriptyline is meant to be reduced by 10 % every 2 weeks but dont know how that is achieved because the doses are 10s, 25 mg etc. I know people who had no major issues coming of them but I bet I wont be one of them because they were different to get started, fried my head.

[@jewelsstone6175]

Nick Drake took this medication.

[@snookaman]

I am thinking of asking my Doctor about me trying this drug, I am a massive Nick Drake fan, how did you find this information ? it was said it was an accidental overdose how he died.

[@Mark.Claughton]

Good video. I have taken this drug on and off for years for insomnia at around a 20 to 25mg dose. Also suffer anxiety and weak bladder although at this dose its not very affective. However after going to take a slash in the night it makes you drowsy so it's easier to fall back to sleep. Can make you feel hungry though

[@michaelthau1007]

Im 52, have had insomnia for past 18 months. Dont want to use Klonopin anymore, tapered down to 0.25mg now. Can go to sleep but wake up after 4 hours. Just trying to see if this would help with insomnia?

[@Mark.Claughton]

@@michaelthau1007 I've moved over to Mirtazapine which I find is better

[@michaelthau1007]

@@Mark.Claughton thanks so much for your response!! Im glad its working for you, I tried it a few times and was way to sedating for me. My Dr suggested Doxepin, I may give it a try Thanks again

[@aaronmaloney8282]

as soon as psychedelics are made legal for medical use all of these poison drugs will be gone. lets hope so

[@noahbrown4388]

🙌🏻🙌🏻🙌🏻

[@willow2290]

I suffered with daily chronic migraines for 10yrs which I had to inject myself with Imigran twice a day. They stole my life as the migraines were totally debilitating and it stole my children’s mother from them as I was bed bound most days. I was referred to a pain specialist as I also suffered with chronic pain in my spine due to my spine being fused and a badly tethered spinal cord. He put me on 50mgs of amitriptyline each night and it completely changed my life! I’ve been taking it now for nearly 5yrs and I can honestly say I’ve only had about 4 very very mild migraines in this whole period! It’s been life changing and a miracle drug for me 🙏🏼 as a bonus it also really helped my nerve pain from my damaged spinal cord. I’ve recently had a nervous breakdown due to something really traumatic and having ptsd. My psychiatrist consultant unfortunately can’t put me on any of the SSRI antidepressants because of the risk of serotonin syndrome mixed with the amitriptyline. She put me on mirtazapine but was horrific side effects and I was taken off it two weeks later. They are not sure if it’s because it was mixed with the amitriptyline? So now they are trying to up my dose of amitriptyline by an extra 10mgs each night working up to a total from the 50mgs I’m already on to 75mgs for my ptsd symptoms and depression. Only I’m really really struggling with exhaustion the next day and not sure I can continue but if I remember right I felt the same way when I first started the 50mgs and it levelled out eventually.. the only other option is for my dr to wean me off all my amitriptyline totally and start me on a SSRI but there’s no way I am prepared to come off it as it’s an absolute God send regarding migraines prevention and nerve pain. I highly recommend it if you suffer with either! Absolutely brilliant review thank you 😊

[@amythus6139]

Did you get this figured out? I've been trying Amitriptyline for the past few weeks, but I'm also on Prozac. I'm curious about how things worked out for you because I'm having some issues but I'm not sure if it's the Ami or what's going on. If you're comfortable sharing I'd love to hear how things worked out for you.

[@berighteous]

I was using this for peripheral neuropathy. I call this AM I TRIPPING It gives me CRAZY CRAZY vivid dreams. I had to stop taking it because I was weary when I woke up in the morning from the long long vivid dreams. I felt disoriented because real life was less vivid than the dreams. My balance was off and I kept bumping into things. And it caused ED.

[@Soychunks]

I appreciate what you’re doing discussing and getting the proper information out there for people. But this drug in particular needs to be further evaluated especially when it comes to withdrawal. I’ve been trying to ween off 5mg for the past year and a half. It has completely destroyed me mentally and completely ruined my GI tract. It’s a shame that this violent withdrawal isn’t talked about. There are thousands of people like me that are trapped by this drug. Long story short, if you’re thinking about starting this drug because a gastroenterologist told you to, do NOT start this drug.

[@andrewmunz1639]

im a trampalene! in 2001 i had my arm and leg got ripped of in a rta.and useing this drug was worst than having my leg ripped off.The side affects were horrable i couldn't sleep for one month!

[@gh-wt2ip]

I took 10mg of amitriptyline it did not agree with me I had extreme mood swings and constipation very dry mouth such a shame as I was hoping these would help with my nerve pain

[@Liptensupe]

Take 100 mg its magic dude

[@ZekeOwen24]

What nerve pain did you have?

[@Liptensupe]

@@ZekeOwen24 none anymore

[@B-Line1234]

@@Liptensupe do you still take it?

[@Liptensupe]

@@B-Line1234 yes

[@froggie6311]

he mentions that amitriptyline doesnt affect dopamine but googling around says it may actually affect dopamine levels. anyway im really liking amitriptyline so far, im taking 75mg per 24 hours. i didnt have luck with all the main ssri meds and also no luck with the other types like mirtazapine, venlafaxine, bupropion, etc. here's hoping it keeps working as for the first time in years im actually feeling normal! (by that i mean, not full of depression, anxiety, worry, etc)

[@elizabritton4039]

A lot of Drs don’t check our vitamin d levels or our b12. I found out late in life to take d3 2000 mg a day I take b12 and magnesium. Magnesium as well as vitamin d does so many things for us. D helps with our well being/depression, magnesium is depleted if people are on acid reflux meds. But also magnesium does so many things for us. I started taking it to help sleep. Turmeric curcumim is good for inflammation but it also helped me with my blood pressure. Anyway good luck. I take amptitryptiline too.

[@NirajPoudyal]

how is the medicine helping now , are u still using it.i ask because I,ve started it with 10 mg. i,ve used many antidepression meds in my past but I stopped in few days and I still have doubs about this one too.

[@froggie6311]

​@@NirajPoudyal hi, i dont know your age but, if you are under age 65 (and also aged above 18), from the leaflet: "The usual dose of amitriptyline for depression in adults is 50mg to 100mg a day". 10mg is way too low, i dont see how that would help, apart from placebo effect. i think low doses like that are either used for older people eg. aged 70+, or if using amitriptyline for something else such as a pain medication. so if u want to see if amitriptyline works for you on depression and anxiety, you will need to go up to the correct dose range. i did start out with around 20mg and then 40mg.. that didnt do anything. 50mg started to feel like it was working but still not enough, so then for me 75mg was perfect to successfully treat my depression and anxiety. sadly i am no longer taking it as it caused me tachycardia. this is a common side effect unfortunately. so i ended up needing to switch to something else, so now im taking vortioxetine 15mg. its too early for me to know if vortioxetine will be good enough for me, but so far its ok; im feeling ok so hopefully it will stay that way. wishing you luck

[@NirajPoudyal]

@@froggie6311 hello. thankyou for taking time to reply.i am 35 yrs old. i was prescribed 10 m for 3 days and then switch to 25 mg. my body says "don,t use it anymore" . i,ve tried many different medicines in my past forheadache, anxiety , pain. today I am thinking about stopping it . I am not good with any of these brain medicines so I,ll stop it and find some otheralternatives to cope with my disease. thankyou. i wish you a good luck. hope you are in good health and spirit.

[@bbt4461]

I’m going to start weaning off Amyltriptine this week. I’m fighting really hard to lose weight and it’s the only reason why I’m not losing anymore. If anyone knows of a substitute please let me know 😊 I take it for insomnia and depression.

[@butwhytho4858]

Keto diet lol. I’ll get hate for this lol but it’s worked for me. Took a year with zero cheat days, but I went from 175 to 138 in about a year with zero exercising. Good luck to you whatever you decide on.

[@Maggie-ep8nl]

Nortriptyline

[@tinam2696]

This is the same reason I am thinking of getting off Cymbalta. Weight gain NO MATTER how much I TRY to lose weight.

[@leocardiamaruta4208]

I'm using this for reducing tingles from Ulmar Neuropathy

[@DiHandley]

How long will it take to get out of my system? I’m having real problems sleeping and strange dreams after having stopped it 5 days ago. It was originally prescribed to help reduce migraines and it did work, but dry mouth at night was terrible. Thanks.

[@nickridley2149]

Been a while since you commented. If you get passed the side effects at first it works for what it was prescribed for. My first time coming it, it was a rough couple of weeks.

[@LarryKippings]

David Handley How did you get on? Please update,

[@jlabdullah9934]

Larry Kippings same needs answer

[@nonsuch]

Thanks for the video! Can you do a video on Paxil/Paroxetine? Thanks a million!

[@scottthrower7637]

I've been on a ton of depression-anxiety meds but Amitriptyline works the best. I'm not crazy about the side effects but it works.

[@debbietaylor20]

I went through hell on zoloft with side effects and withdrawal. Are the side effects as bad on this ? Want to try for anxiety .

[@fernandog9697]

Can you describe the side effects ? Plese

[@MM12331]

Its the side effects of benadryl.

[@DanielSRosehill]

Anybody else been prescribed this for functional dyspepsia? Have it since gallbladder surgery - very tough condition!

[@Shir2024]

My first time see this amazing video very clear information thank you so much!

[@jessicaebenezer9103]

I feel like hibernating for days, taking this....

[@terrir.7604]

22 years on this med. Has given me Tachycardia and now QT Prolongation. Just hope I can get off it. Cardio doc wants me off.

[@LarryKippings]

What dose were you taking for that long? Have you tried to stop? How did it go? I’ve been taking 10mg for 8 years. Am considering stopping myself.

[@terrir.7604]

@@LarryKippings Hi...sorry just now seeing this. I've been on 25 mgs for 22 years!! I haven't tried to stop since it's working for me for my TMJ. I took it years ago for 5 years and getting off then was a little hard...mostly nausea, dizziness, motion sickness, head pressure, eye pressure but it was all mild. Now it would be awful! I've read of people recently getting off it and one going through a taper right now and it's been hard for her. I just say take it super slow!! How many mgs are u on? I found out a supplement I was taking was actually increasing the levels of my Amitriptyline and it was giving me the QT...I stopped that supp and I no longer have QT...just some Tachycardia every now and then. Just know that Ami is notorious for causing these kinda heart conduction issues. I would definitely consider trying to get off slowly and if u need help reach out to SurvivingAntidepressants.org. to do a slow taper down. I think I'm trapped on it till I get done with TMJ treatment which will be a few years.

[@terrir.7604]

@@LarryKippings you are on a low dose..u may do just fine....best rule is to do 5% to 10% reduction per month. If I ever taper it will be 1 mg a month. And once you get lower you have to go slower...just go by how your body feels and keep a journal.

[@ansarimaulidilawal6634]

did you feel like PVC or VES?

[@terrir.7604]

@@ansarimaulidilawal6634 what is VES? I do have some PVC's...all benign. I'm doing fine...no more QT prolongation but Tacyhcardia persists during the day.

[@scavanger1000]

Just got prescribed for insomnia, $4.83 very nice, cheaper than the sleeping aid I was taking

[@khalilazagoth568]

I have herniated disc in the lower back for 3 years, last August I started to take this medicine 10 mg a day, then 25 mg for 6 weeks, and now I'm taking 75 mg, I don't know till when I have to take them

[@8QQ8]

Any side effects?

[@JohnKobaRuddy]

If you have come across this video and you have GERD/GORD/NERD and IBS please beg your doctor for about 100-150mg of amitryptaline it’s been a god send! I have sleep apnea from ibs stomach pains and constant stomach acid from gerd and I’ve struggled for three years now and finally I was put on 100mgs and it’s been a life saver. Kills pain in 30 minutes and I can sleep now for a change. And I’ve stopped my fimotodine Tablets. And I’d tried them all ranitidine lanzoprazole emeprozol esomeprozol pantoprazole etc etc and they’ve all failed!

[@demicynthiaeaston2130]

Why does it cause weight gain?

[@indianrailwayszoom]

Best doctor ever

[@haileyo5433]

IBS gal over here. Love the quick info!!

[@juvi6787]

Thank You for sharing! This was a lot more information than I got from my doctor! I think I'll skip this medicine - only 10 mg. daily though, as I prefer to stay slim at all costs. Of course I wasn't told that it will mean weight gain. I like to know what I am putting in my mouth and how that will work in order to make an informed choice for myself. Then I will know what is worse, the condition I am trying to treat, or the side effects of the medicine. Thank You! I will subscribe to you.

[@tyrel-fg7zf]

His dead

[@theeditor1149]

I am on this for depression and sleep problems and I just hate taking it. It was too heavy for me and i could not wake up in the mornings. I am extra tired and it causes such vivid dreams i wake up with my heart racing. I also have to take it very slow when i wake up because I would wake up drowsy and feel dizzy. If anything it makes me feel terrible overall. Doc told me to halve it but it still makes me feel messed up. Depending on your health it might cause too many symptoms in some people.

[@joeygamio4716]

Thanks doctor I was just prescribed this pill it's not doing anything.. but it was given for occipital nerve pain

[@EC-yd9yv]

The pill quality varies from one manufacturer to next... anybody find which brand/mfr is best?!thank in advance. Best wishes for pain free etc to all

[@SA77888]

He got an unusual manner......its almost like hes annoyed that hes telling you this shit.

[@Jupiterascend9]

Lmaoo 😂

[@Dave-if5qj]

Tricyclics are under utilized In my opinion Especially for treatment Of vary severe depression

[@soufianesetli4536]

The most effective drug ever fast action 2

[@deborahhatcher186]

You are right, (elavil) Amytryptaline is the standard off all antidepressants, its pretty safe but you will have sleepiness, this drug is what every antidepressant is compared to...... even to this day, every drug has to be at least 20 percent, well never mind to technical.....

[@gregorymalchuk272]

@@deborahhatcher186 How is it compared to nortriptyline?

[@garysimone4977]

@@deborahhatcher186 how is Ant working for you and I need it for sleep what think

[@rannveig3117]

My face was swollen and I was very tired with low energy. I only had 10 mg a day for migraine. Didn't work!

[@ianshilling5863]

Had pains in my lower back and stomach got tension headache to the pain as gone in my back and stomach nerve ploblem they think still have headaches and worrying about things to much as not help hopefully this drug will kick in and I get back to normal living I'm just on 10mg.

[@kirkkoblect5915]

Does this drug have withdrawls if u stop taking it? I dony want to be hooked on anything else for the rest of my life. Recovering drug addict