What is the Nernst potential? A function of ion channels and ion concentration gradients.

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Professor G (Pharmacology)

Professor G (Pharmacology)

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The equilibrium (or Nernst) potential for an individual ion is the volage at which the opposing electrical and chemical driving forces for that ion to cross a cell membrane are balanced. The resting membrane potential of a cell is determined by the Nernst potentials of all ions that can permeate the mebrane at rest. The Goldman-Hodgkin-Kattz equation extends the Nernst equation to account for all permant ions. This video explains (1) the chemical and electrical forces that affect ion flow across a membrane (2) how these forces give rise to the Nernst potential (3) the Nernst potentials for K, Na, Ca and Cl ions (4) the relationship between the Nernst equation and the Goldman-Hodgkin-Katz equation.
#physiology #nernstequation #ionchannel

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