Where Does Insulin Resistance Come From? with Dr. Ben Bikman

The focus of the classroom today is to help you better understand the origins of insulin resistance.
Learn more at: www.insuliniq.com
#insulinresistance #metabolicsyndrome #metabolichealth #type2diabetes #type1diabetes #weightloss #intermittentfasting #intermittantfasting #fasting

[@Lemminaide]

I’m 78. I’m a learning more about how my bodies works than I ever imagined I would. Thanks. I preference to heal / stay healthy thru lifestyle and diet. I refused to be one of those weak old women with a big belly, skinny legs and a drawer full of prescription drugs.

[@insuliniq]

Good for you. We’re behind you all the way. Thanks for commenting.

[@clovermark39]

Well done. Wish I could get my friends to understand. Drugs are not good.

[@pampuskar4778]

How are these people able to get to 500 pounds and and more on these shows about weight loss. It seems like an impossible situation!

[@Lemminaide]

@@pampuskar4778 I am at normal weight for my height. That’s an excellent question for Dr Bikman.

[@sarahg1077]

Isn’t it comical when people say your body will go into starvation mode when you skip a meal. Glad you said that the body is in fasting mode until all the fat stores are used up and the body starts breaking down muscle and bone.

[@luvlabso130]

Obesity is epidemic

[@tanyareynolds154]

Loving these class room lecturers 😁 feeling very blessed to be able to watch Thank you Ben for sharing your knowledge 🙏 x

[@insuliniq]

Glad you like them!

[@chrisdat1]

Love this series. So good to get the science behind popular keto topics. I hear confusing and sometimes contradictory information. I’m very thankful for you taking the time to explain simply and clearly, complex subjects. Also, thanks for the myth-busting while remaining professionally courteous.

[@insuliniq]

Thanks, Chris, for watching and for taking your time to write this kind comment. I appreciate it.

[@ActivateMission2ThisTimeline]

​@@insuliniqIf allulose is created byGM0 glyphosphate/pesticide sprayed corn vs a organic fruit would they not be different in contamination or genetic make up?

[@annmckeever5523]

I only recently discovered the Insulin IQ series. I'm so excited to watch and learn from every single one. Thank you, Dr. Bickman. Your work is amazing and critically important.

[@insuliniq]

Thanks. Be sure to sign up for a free Basic Membership on my website: www.insuliniq.com

[@tracy3812]

Ben, it would be great if you could take over the TV channels (like the President does) and teach these classes. America (and other nations) need to hear this.

[@vlastimiljanko8638]

Professor Bikman.... Great lesson again! Thank you for your time and hard work,!🙏

[@insuliniq]

Thanks for watching and commenting. I appreciate it.

[@erastvandoren]

He is a charlatan

[@vlastimiljanko8638]

@@erastvandoren you must have pretty miserable life that trolling is your idea how to spend your time......

[@kiloboba]

You are amazing Ben. Your logic is sound and explanations are clear. I could watch this on repeat. Thank you for sharing your findings here for everyone!

[@ProductiveHealthPH]

Great lecture❤! I have read the "Why We Get Sick" I loved it, my most favourite book.

[@insuliniq]

Thank you.

[@KlaudiaValentova]

I am honoured to watch your lecture! Many thanks Mr.Bikman 👍

[@insuliniq]

Thanks for watching.

[@dchildr360diurnalnutrition]

Thank so much for this better understanding of insulin resistance!!! This information helps us helping others organize our thoughts around insulin resistance. A wonderful and very constructive tutorial.

[@insuliniq]

Thanks for your kind comment.

[@Kathleenschweiker]

Thanks for sharing this clinically relevant research.

[@allieshepherd7860]

Wow, excellent! This encourages me to continue on Keto/Carnivore. I had covid 2 years ago, hospitalized for 15 days, and was very ill. I'm just starting to get my energy back (and losing weight), by eating meat, meat fat, and a little vegetables. Thank you so much for helping me understand what is going on in my body, and how to continue to heal my health.

[@insuliniq]

Thanks, Allie, for your comment.

[@Padraigp]

Get them greens into you! Magenisum omega 3 fats vitmin k ...and natto for fibrin and clotting. Iodine and selenium for your hormonal system the day i took iodine it was like my brain had had a shot of coffee the fog just lifted from my mind and i could think again. I didnt get energy with it as some do untill instarted selenium as well. Im almost normal now when i take everything when i forget for a while I go back down and my hair all got bad after covid that is still falling out when i brush it and getting thin...

[@murdermittensnyc]

Excellent expression of primary vs secondary.

[@veraarena1583]

Excellent! Thank you!

[@KlaudiaValentova]

I love your lectures!

[@gladysquinones4220]

Thank you for your classes. 💕💕🙏🙏

[@bernadettebecher4689]

Have learnt so much. Thank you for educating us. Your time and efforts are really appreciated.

[@joaoveloso4954]

Wow Amazing listening to someone that really understands the topic they’re covering. So that’s why I was getting intense muscle cramps, spider veins, etc…

[@sharonlasper8999]

FANTASTIC, THANKYOU 😊

[@JohnSmith-fl5qn]

Congratulations for your teaching

[@joseyantorno757]

Thnak you Dr Binkman. I listen and see you from Argentina, South America

[@insuliniq]

Thanks, Jose.

[@crackergirl49]

Thank you

[@clovermark39]

33:02 Thank you this was really interesting.

[@JimWooddell]

Ben, in your book, Why We Get Sick (a very good book worth every penny), you briefly touch on brown fat and cold skin. 1. Where is this brown fat on our bodies? 2. Where did the specific temperature come from? 3. How long does you skin need to be exposed to this temperature in order for it to work at lowering insulin? Thank you. And thank you for your very important work.

[@iangorner]

Thank you Dr Bikman. I have been following you since reading your book a few years ago. Great course! I have also been doing courses through the Noakes Foundation…..so much to learn! The infinite complexity of the human being!

[@insuliniq]

Well said. Thanks for your comment.

[@47retta]

Why is the fructosamine test useful? When would you use it?

[@marypohja2812]

Ty. Nice to know about allulose. .

[@insuliniq]

Thanks for commenting, Mary. You may want to watch this video with Dr. Bikman: kzbin.info/www/bejne/kJeViaV_qcp-g9k

[@Frostbiker]

Thank you Prof. Bikman. I would love to learn more about the evidence for adipose tissue being the first domino piece to fall to insulin resistance, rather than e.g. skeletal muscle, as folks like Prof. Gerald Shulman propose. Also interested in any insight you have on the specific intracellular causes of insulin resistance. E.g. Doc. Jason Fung appears to support the hypothesis that it could be as simple as an excess of glucose inside the cell preventing the existence of a suitable gradient across the membrane to transport glucose into the cell, if I understand his argument correctly.

[@susanbeever5708]

When the cell is insulin resistant and blocks the insulin receptor insulin stimulates TRPV1 that puts glucose into the cell without using the insulin receptor. This causes too much glucose and lipid oxidation and too much reactive oxygen species production in excess of the cell’s antioxidants. This leads to general inflammation and of course oxidized lipids are core component of atherosclerosis. The low carb or keto diet limits glucose available for oxidation secondary to TRPV1 putting glucose into the cell. When I maintained a low carbohydrate diet I reversed my insulin resistance measured by 6 hour oral glucose tolerance test and measured c-peptide also significantly reduced. At the same time my osteoporosis resolved and my atherosclerosis significantly reduced.

[@rosalbadelriogarcia9598]

Awesome! #carnivorecure #revero #lutherburbank #reindeerherdsman #transhumancy #lutherBurbankAndTheYogi

[@JasonBuckman]

"When I maintained a low carbohydrate diet..." Are not doing low carb anymore?

[@susanbeever5708]

@@JasonBuckman yes, I am still on the low carb diet. I was trying to give a timeline of events as my bone mineral density loss switch from loss to gain and it began with the low carb diet and then accelerated 8 months later when I stopped Oxcarbazepine that up-regulates TRPV1. So the stimulation of TRPV1 by glp-1 with the consumption of carbohydrates and the up-regulation of TRPV1 both created the disease process.

[@ld9044]

❤❤❤ Dr. Ben !

[@oibal60]

I could not RESIST this posting on insulin.

[@curlyq9901]

Thanks!

[@insuliniq]

That is so kind of you. Thank you very much. Not at all expected, but appreciated.

[@mikoc7633]

Would love to be a part of this study. I do live in Weber county, but I would definitely travel to Utah county to do the study on this issue. I've been struggling with this for many years and been tough to get the water retention, inflammation down, so that I could lose the hundred pounds I need to, tried everything, please reach out if you see this message! 🙏🏽💜

[@jorgefranco8522]

Thanks Dr. Bikman!! Love ya man!! God bless. I wish I could ask you about my unique situation. Not sure if have time to opine this but here it goes. I am a lean and workout a lot. I eat a ketogenic diet. My AIC is 5.9, fasting insulin 2.8, triglycerides 66, LDL 140, but my HDL 38.5?? Not sure why my HDL is so low. Should I be concerned? Again appreciate your knowledge so much!!✝️✝️🙏🏽🙏🏽🙂

[@jobrown8146]

Dr Ken Berry has a couple of videos on how to increase HDL. You can find 2 videos on YT by searching _dr ken berry raise hdl_

[@rosalbadelriogarcia9598]

example, 200 (triglyceride level) ÷ 55 (HDL) = 3.6 (triglyceride HDL ratio). Ideal triglyceride HDL ratios... _ideal: 2.0 or less _good: 4.0 to 6.0

[@Debbie-jz6ef]

Dr Bikman has said the ratio of triglycerides to HDL needs to be less than 1.5 not between 4-6. That's way too high. I just watched a video with him saying this yesterday and I wrote it down. 👍

[@GG-tk8cq]

The liver stores like 5 years of B12 so very difficult to deplete the bodies B12 stores. So the Stanford twin study about depleting B12 in 2 weeks is questionable.

[@vincentpattavina2120]

Neither of the books on Dr B’s shelves is available at my county library and branches. Available, however, are 19 pages listing vegan cookbooks and how to be vegan, for both adults and children

[@menarobertson84]

😂 ironic

[@theskyehiker]

Make a request that your library acquire his books. It is,after all, a public library. In my experience libraries are very open to getting requested books. Maybe the vegans in your community have been better at asking for what they want.

[@oibal60]

SUBSCRIBED!

[@Jan1Brown]

Thank you so much....wonderful to understand and solve problems my body has by cutting out carbs! Can insulin resistance help create thyroid problems? Very best wishes 😊

[@rosalbadelriogarcia9598]

Alulose if it comes from corn or or starch, wouldn't it be like vitamin C.? Because it's sourced from a fruit or vegetables or plants it will always spike your glucose...?

[@marypohja2812]

Would you please list the study on more importance of triglyceride to HDL ratio than levels of increased LDL contributing to heart disease. Thank you

[@insuliniq]

Hi Mary. Thanks for your question. You may want to go to our website and ask our team: www.insuliniq.com

[@marypohja2812]

Thank you. Will do.

[@shirleypeterson6393]

❤❤❤❤❤❤

[@codegate615]

would love some timestamps...

[@47retta]

I've noticed lately that when you're in the hospital, and they give you prednisone, they also usually give you insulin to keep your blood sugar from spiking. Is there a better alternative?

[@adelebayly9701]

Interesting

[@felixaudet5860]

Could long COVID and or other chronic infections cause insulin resistance?

[@jaycarver4886]

I hope he answers!

[@yoso585]

Heck yeah. I’m 6 weeks from contact and still up about 20.

[@woman4womenkids547]

It is very strange that western breakfasts and desserts are much the same, just configured differently.

[@ellingolsen3194]

I can't remember if it was in this video you said that uric acid causes an inflammation that raises the glucose level. And that this can lead to insulin resistance. Elsewhere I have read that insulin resistance causes an increase in uric acid. Is it a vicious circle? If so, can one break out of it without medication or is medication the way to go and then stop taking it when one is clearly no longer in MetS territory? I indicate that intermittent fasting is not enough.

[@perrydoerr8668]

Soooooo could my enlarged prostate and the inflammation associated with that affect my insulin response. Like driving up my sugar levels

[@yoso585]

Certainly

[@tammylynn5667]

Does this process also apply to lipodemic fat cells?

[@Patricia.resells]

What is the relationship between exogenous opioid use and insulin production?

[@dusanjerinkic6330]

Hunger centar in CNS, dopamine, incretins....rewarding system integrating opioids, alcohol, food, tobacco...Insulin is lowered under the influence.

[@Patricia.resells]

@@dusanjerinkic6330 Thank you. Have you published on this? Seeking citations. 🙏

[@nikkiguerlain]

I watched a presentation a while ago that said C Diff loves trehalose and it’s often added to ice cream to adjust its texture/softness. Also in some mushrooms etc. In any case, I don’t really want to eat anything that C diff is like YUM. No thank you.

[@karenohanlon4183]

I think if you have a lot of fat stored then a supervised fast could help release the stubborn fat. Even doinh Alternate day fasting and restricting carbs and a three day fast . My body refuses to part with its stores. Its frustrating. Its like the body saying I know what you are doing and the metabolism just plummets.

[@insuliniq]

You may want to consider some personalized coaching for a few months to try to get to the bottom of these issues. We are all different... and sometimes a coach can help. We have lots of good ones: www.insuliniq.com/private-coaching

[@jaycarver4886]

A lengthy water fast might help a lot. I did 21 days which totally cured my rosacea and I also lost weight. Curing my skin issues was the reason I did it though.

[@yoso585]

Either you are eating too much or your body is living off muscle tissue. How do you know you are not burning stored fat?

[@ActivateMission2ThisTimeline]

If allulose is created byGM0 glyphosphate corn vs a organic fruit would they not be different in contamination or genetic make up?

[@rameshb9525]

I have been low carb high fat for more than 7 years and still have high uric acid. Why?

[@luvlabso130]

What do the animals eat that we eat?

[@Padraigp]

Crp might be good for showing somrthing but ive had inflamation and had crpless than 1 which is the norm. It doesnt seem to be much of a subtle scale. Untill its over 1. So if its raised maybe thats shows insane inflamation but you can have inflamation and not raised crp.

[@user-nh9zq5re3v]

Was there a retroactive study or retroactive research into offspring of women who had low B12 during pregnancy...? It seemed to me that the researchers found the offspring were all obese. I have seen something like that in my practice. The conundrum is that often the childten are underweight - even scrawny until mid childhood or puberty...

[@Pmd-bs6zv]

I'm eating carnivore and consuming around 70 to 100g of butter a day but my blood sugar levels are between 5,5 mmol/l to 7,2 mmol/l . My sleep hasn't improved. What would be the cause of this,?

[@AVitkouski]

One of the backup systems that makes glucose and releases it into the blood to be used for energy is the liver. When glucose levels go down, insulin stops being secreted by the pancreas and the low insulin level causes the liver to start making glucose and liberating it into the blood for distribution. When we eat, we no longer need the liver to continue to provide glucose. When we eat, blood glucose levels rise as the food is absorbed, the increased glucose levels stimulate the pancreas to produce insulin, the rising insulin level in turn acts as a signal to the liver to stop producing glucose because the body is now getting enough glucose from food. In the normal state, the production of glucose by the liver is regulated by insulin levels in the blood. When blood sugar levels rise, insulin is secreted; the increased insulin level signals the pancreas to stop production of glucose. In diabetics there is always insulin deficiency so the signal to the liver to stop glucose production is blunted. In addition there is almost always a degree of insulin resistance, because the liver is resistant to the effects of insulin, it keeps on producing glucose even if glucose levels are already high and insulin levels are high. The liver manufactures glucose in an unregulated manner all night and consequently the blood glucose level which may have been normal or slightly elevated at bedtime progressively increases overnight and the fasting glucose in the morning is too high (frequently the fasting glucose is the highest glucose of the day). A high glucose in the morning is an indication that the liver is overproducing glucose at night. Often the raised morning glucose is the first sign of diabetes that we see. Looks like your liver is insulin resistant... www.diabetesclinic.ca/en/diab/1basics/high_morn_glucose.htm#:~:text=One%20of%20the%20backup%20systems,into%20the%20blood%20for%20distribution.

[@FlailingJunk]

"Vitamin" A

[@GG-tk8cq]

So fructose has a double whammy no ? it directly raises insulin and it also raises insulin via uric acid ? Fascinating how Uric acid can raise insulin. I just had some bloods done 3 months ago. My A1c was 5.7%, fasting glucose was 92. My fasting insulin though was 14. Funnily enough my Uric acid was outside of the upper normal range. I looked at my diet. Apart from eating copious amounts of white rice, pasta, chocolate and other refined carbs I used to drink a bucket load of apple juice, like 500ml a day easy. Also I was pretty heavy on the whole fruit but I'm sure it was the liquid fructose that was doing the damage. Needless to say I no longer drink liquid fruit.

[@AngeloJimenez8]

If doctors knew as much as you about metabolism, we'd all be happy campers.

[@insuliniq]

Thank you for both your comment, and for your kind gift. You’re very generous. Please reach out to me and my team if there is ever anything we can help you with: www.insuliniq.com

[@ftmrivas3043]

🙏🙏🙏

[@sandraobermaier2955]

How do you get rid of insulin resistance if you have non-diabetic gastroparesis?

[@insuliniq]

Thanks for your question. You may want to go to our website and ask my team: www.insuliniq.com

[@graphicmaterial5947]

14:17 Finally! The root cause - frequent exogenous carbohydrates. What took you so long?

[@alistairmeney9806]

The idea that raised insulin itself creates insulin resistance I’ve never quite believed - it’s often said reductionism is nonsense yet we jump to it all the time. Eat a high sugar meal. Insulin rises ( the beta cells don’t really respond to glucose.. but that’s another story..). But insulin is a master hormone and regulates many other hormones. For the next 5 hours or so (according to experiments) as sugar levels start to drop this itself is perceived as an emergency and Adrenalin and cortisol rise. So we’re really back to the 2nd primary cause apparently. In the case of isolated cells in culture, don’t they require to produce inositol and it’s phosphates metabolites to allow insulin receptors to work - where are they getting the substrate force this - maybe I’m missing something here?

[@JasonBuckman]

It's proven that high insulin levels induce insulin resistance. It can be seen with people with insulinoma.

[@jberts3141]

I don't think I heard anything about keto induced insulin resistance? Long term keto doesn't seem to be optimal either.

[@samuelspade889]

Allulose gave me diarrhea so bad, I couldn’t leave the terlet. Perhaps some people cannot handle it… I would imagine the GLP went out of me with everything else, lol.

[@isabellekeyzer]

isn't aspartame toxic? there seems to be a correlation with brain tumors

[@GG-tk8cq]

Plenty of seriously strong muscled vegans around that if you stand them next to the average guy eating predominantly carnivore there's no comparison ? also you don't have to eat low fat on a plant based diet. That said I think the pescatarian diet is the best.

[@mamabear9389]

Aspartame does not sound good regardless of insulin effect.

[@jeffg5009]

IF as you say Chronic Elevated Insulin Is Cause of Insulin Resistance THEN Why did my Dr tell me that I have elevated Blood Sugar I am Insulin Resistant Dr Prescribed So Increase Insulin By Injecting More Insulin Long Acting Every Day And Take even more Fasti Acting Insulin before every Meal I asked Dr are you going to measure How Much Insulin I have Now ? Dr said we'll measure that at some point Later ? ? ? Why would they Now Measure before you start artificially increasing ? This Dr plan to Lower Insulin Resistance Is By Giving MORE INSULIN and Told me to STOP eating only 1 or 2 Meals per day & START eating 4 to 6 Meals per day And She wants me to Start Taking Medication that has the side effect of Causing Weight Gain

[@insuliniq]

Thanks for your questions. You may want to go to our website and ask my team: www.insuliniq.com

[@Primetime_dads]

Are yall low carb high saturated fat, or low carb high unsaturated fat

[@lemunbalm3731]

Low carb/high saturated fat.

[@Primetime_dads]

@@lemunbalm3731 👍

[@yoso585]

Depends on my stock of avocados. But even then, by general standards, I’m sure I’d be classified very high saturated.

[@darcy2965]

I've tried to listen to 3 of your videos to learn. All way too complicated and technical.

[@daisy3690]

[@t.p.7373]

Thank you