Why PRP or PRF Cannot Replace Dermal Fillers

[@Shahzad-Khan]

Your deep knowledge and the satisfaction you have explaining these concepts brings me joy. Keep up the great working in dermatology

[@AmiyaPrasadMD]

Thank you for your kind words, Shahzad Khan. I'm glad you find the videos helpful. And thank you for watching!

[@dr.kamleshmaywad8636]

You are excellent teacher as well as surgeon

[@AmiyaPrasadMD]

Thank you for your kind words, @dr.kamleshmaywad8636! Much appreciated!

[@dr.kamleshmaywad8636]

@@AmiyaPrasadMD thank you so much sir 🙏

[@jordensosa9310]

Salute Amiya Prasad .Great job.

[@AmiyaPrasadMD]

Thank you for the appreciation, @jordensosa9310. And thanks for watching!

[@louisah6020]

Unfortunately I am not a candidate for filler in my tear trough. Would PRF then be a good option if it's someone's only option to help with hollowness?

[@AmiyaPrasadMD]

Hi @louisah6020, As explained in the video, PRF doesn't have the same structural strength as a hyaluronic acid filler, and the limited volume effect of PRF only lasts about two weeks. I would also have to confirm that you are not a candidate for filler, as hyaluronic acid fillers are hypoallergenic, and biocompatible since hyaluronic acid is naturally present in the body. I hope this clarifies things for you.

[@jammybind4583]

If Under my eyes is very thin and white do you still recommend fillers ? Thanks

[@sidrakhan4409]

What can be done if there is volume loss at the outer corner of eyes?

[@AmiyaPrasadMD]

Hi Sidra Khan, Volume enhancement is often done at the temples, but I would have to examine you to determine if this is the right treatment for your case. I hope this clarifies things for you.

[@BIG-T93]

Which one is better between PRP vs PRF? For dark circles

[@AmiyaPrasadMD]

Hi @BIG-T93, It's important to keep in mind that PRF is still PRP. I normally use PRF when a time release of wound healing, and growth factors are needed, but both can be used for dark circles effectively. It's also important to keep in mind that under eye dark circles may need a combination of procedures for best results. You can refer to this recent video about it - kzbin.info/www/bejne/hniQd6WJhLyErLM

[@jackandrade3966]

Would prp...itself be good for dark circles or would it need to be combined with say co2 laser...rather than the use of fillers...seeing how fillers can last many years

[@AmiyaPrasadMD]

Hi Jack Andrade, PRP (or PRF), and CO2 laser can be used by themselves, or combined to treat dark circles, depending on the individual, and their skin type. Fillers are used to treat hollowing, which can possibly contribute to the appearance of dark circles. While a physical examination is needed before making specific recommendations for you, these videos feature the ways I treat under eye dark circles in my practice: kzbin.info/www/bejne/h3PZm52srbWnaMk kzbin.info/www/bejne/iWfCn4eIp5ann9E kzbin.info/www/bejne/oIK4k2lth9WUd68 kzbin.info/www/bejne/iHmtoJeYaZhqpZY

[@jammybind4583]

Hi dr I want to ask u pls if me iron and vit d are low do I still get good results from prf under eyes

[@AmiyaPrasadMD]

Hi @jammybind4583, Iron, and vitamin D levels can possibly be raised prior to undergoing treatment. You can still get good results with PRF as there are other factors besides iron and vitamin D that help with skin rejuvenation. I hope this clarifies things for you.

[@Maria_Shoaib]

Hello doctor, I saw your video about prp's benefits for thinned skin due to thermal devices (from steroids in my case), how do you compare prp and prf in that scenario ???

[@AmiyaPrasadMD]

Hi @Maria_Shoaib, PRF is still PRP, but a thicker, more concentrated form. I generally use PRF if a gradual time release of healing and growth factors are needed. I hope this clarifies things for you.

[@Niloshhh3]

Hello, my doctor recommended hyaluron because I have deep dark circles under my eyes and you can even see my tear trough. However, I don't dare do it because of the many risks and I don't want to do it because I'm still young. I'm 19. Would prp or prf work in my case? maybe also with the co2lasr

[@AmiyaPrasadMD]

Hi @Niloshhh3, I usually don't recommend treatment for people your age because the face is still growing, and maturing, and will continue to until the early 20s. Issues like hollowness under the eyes that show dark circles can be outgrown during this time. I normally suggest treatment in the early 20s at least after the face has stopped growing, and the issues still persist. I hope this clarifies things for you.

[@Niloshhh3]

​@@AmiyaPrasadMD could i use prp? Because i think i have genetics eye circles. Since i am Young. But i need to do something because i always look so tired. Hyaluron i dont want

[@AmiyaPrasadMD]

Hi@@Niloshhh3, I hope you understand that in order to recommend specific treatments for you, I would have to see you in consultation like your doctor did, especially since you are younger than the minimum age of my usual patients.

[@debbiewagner5332]

Hello I have a history: face lift June of 2022; resulted in infection mycobacterium Chelonae. I was sent to infectious disease; on medication for a year and Plastic Surgeon wants to redo lower face. What are my cautions about? I do not feel comfortable about this. My neck is swollen and disfigure. Thank you I have consulted with you by phone a year ago; love your information videos.

[@AmiyaPrasadMD]

Hi debbie wagner, I hope you understand that I would have to examine your face, and your medical records of your surgery to assess the details needed for a proper second opinion. I hope this helps you.

[@user-fw7nm4pm3r]

Hi Dr. Prasad. What is the difference between PRF or EZ gel/biofiller?

[@AmiyaPrasadMD]

Hi, EZ Gel is PRF, but mixed with the protein albumin, which is produced by the liver. This combination makes the volume effect of the treatment last longer, as volume from PRF alone would only last 7-10 days, while EZ Gel would last 3 months. However, depending on the viscosity of a hyaluronic acid filler used in conjunction with PRP or PRF, the volume effect of hyaluronic acid fillers last 1-2 years. EZ Gel is for people who want to avoid hyaluronic acid fillers, but hyaluronic acid fillers are already biocompatible and hypoallergenic as hyaluronic acid is naturally found in the body to retain moisture, and to lubricate joints. I hope this clarifies things for you.

[@user-fw7nm4pm3r]

@@AmiyaPrasadMD thank you for that clarification Dr. Prasad. So EZ gel just adds a longer lasting volumetric effect than PRF. However all the rejuvenating effects and other properties are similar for both products. That makes sense. Thank you

[@AmiyaPrasadMD]

Yes. You're welcome, @@user-fw7nm4pm3r

[@sherriscorner2015]

@@AmiyaPrasadMD thank you for answering this. Would 3 treatments of EZ Last longer than 3 months?

[@AmiyaPrasadMD]

Hi@@sherriscorner2015, You would have to get EZ Gel administered at least every 3 months to sustain the effects, but a hyaluronic acid filler can sustain its effects for about a year. I hope this clarifies things for you.

[@Nowara84]

Hello doctor , thank you so much because you answer everybody on their questions.. iam kinda lost now, some people say fillers are bad in long terms and could stay till 10 years and over even if they are from a good quality, other doctors say that fat transfer is the best choice (iam talking here about hollowness under the eyes area) I really don't know which proceadure to choose ?! I have hollowness and some dark circles caused by my very bad nose allergies that I've been suffering from my whole life .

[@AmiyaPrasadMD]

Hi Nowara84, Fat transfers under thin eyelid skin is highly prone to complications, so I don't recommend it, or perform it, but as an eyelid specialist I often have to surgically remove it after it is performed by non-eyelid specialist surgeons. I do usually recommend and perform soft hyaluronic acid fillers for under eye hollowing. You can refer to these videos about it: kzbin.info/www/bejne/o3_SkHh4mKmcZ80 kzbin.info/www/bejne/jKvdpJWEedGUfrM Dark circles can be treated with PRP, or PRF as shown in the video, but there are other treatments that can be used in combination. While a physical examination is needed before making specific recommendations for you, these videos feature the ways I treat under eye dark circles in my practice: kzbin.info/www/bejne/h3PZm52srbWnaMk kzbin.info/www/bejne/iWfCn4eIp5ann9E kzbin.info/www/bejne/oIK4k2lth9WUd68 kzbin.info/www/bejne/iHmtoJeYaZhqpZY

[@louisah6020]

@@AmiyaPrasadMD I was told and have read (by many experts) that one should not get under eye filler if they suffer from allergies/nasal congestion, etc., that they essentially are not the right candidate and that it will lead to further complications. I would love to hear your opinion on this since you are recommending filler for someone with allergies.

[@AmiyaPrasadMD]

Hi@@louisah6020, Filler treatment can still be done with people with those conditions, but I would need to assess their individual situations first before recommending filler treatment. I hope this clarifies things for you.

[@jpramos36]

I just returned from a plastic surgeon. He told me that PRP would help my very minor lower eyelid retraction from a lower blepharoplasty I had 4 months ago. Will PRP indeed fix a lower retraction?

[@AmiyaPrasadMD]

Hi J Ramos, PRP is a treatment for skin quality improvement. Lower eyelid retraction can be due to unnecessary eyelid skin removal, compromised lower eyelid support structures like the orbicularis muscle that was likely cut through in your surgery, and the lateral canthal tendon that may have been affected by your surgery, all of which PRP does not treat. You can refer to these videos on the causes, and specialized repair of lower eyelid retraction: kzbin.info/www/bejne/rYWcnoZ4q6afpNE kzbin.info/www/bejne/bZaTXpuworOUoNE

[@mchris4708]

Love the new intro!!!!

[@AmiyaPrasadMD]

Thank you, M Chris! I'm happy you like it!

[@weireffie29]

Thanks

[@AmiyaPrasadMD]

You're welcome, @@weireffie29. I'm glad you found the video helpful.

[@NinorahDeux]

Hello doctor, why not using PRF with mesotherapy technique to tighten skin ?

[@AmiyaPrasadMD]

Hi @NinorahDeux, I do administer PRF for improving skin quality, but mesotherapy is not FDA approved in the US. Also, I do prefer more targeted, and customized injection treatments than mesotherapy that involves many needle pokes through the skin. I hope this clarifies things for you.

[@NinorahDeux]

@@AmiyaPrasadMD Thank you !

[@AmiyaPrasadMD]

You're welcome,@@NinorahDeux

[@sanarora]

Great video Dr Amiya. HA fillers can cause scar tissue so are prf/ez gel better options for areas like lips?

[@AmiyaPrasadMD]

Hi @sanarora, Hyaluronic acid fillers can be administered without creating scar tissue. As explained in the video, PRF does not have the same strength as hyaluronic acid fillers, and PRF breaks down after two weeks, so it loses its volume effect quickly. I hope this clarifies things for you.

[@KarolinaSo-xc4lq]

Can you do prf while having malar bags caused by oedema, or the oedema from prf procedure worsen malar bags?

[@AmiyaPrasadMD]

Hi @KarolinaSo-xc4lq, It depends on the area that is being treated with PRF, and how the treatment is one. I have treated some cases of malar bags by improving skin quality with PRP, which alone doesn't have that much of a volume effect. PRF can have a temporary volume effect as it's a thicker material. I have also blended malar bags with hyaluronic acid filler so they don't look as prominent. While something similar is possible with PRF, or more volume from PRF can make malar bags look prominent, the volume effect of PRF only lasts about 3 weeks. I hope this clarifies things for you.

[@fatoudiop3593]

Hi Dr Parsad, Thanks for this great video.I wish I had seen it sooner. I had EZ gel injected to my under eyes but as you mentioned it has not fixed the volume loss issue. Is it safe to have HA injected 1 month after this previous EZ gel injection?

[@AmiyaPrasadMD]

Hi @fatoudiop3593, Thank you for watching. Safety depends on the experience and expertise of the doctor performing the filler injection, but it can be done one month after your previous treatment. I hope this clarifies things for you.

[@hadarherchkovich6009]

Love the new video! I have a question , 7 months ago I did eye filler and got malar edema. The edema isn’t very severe but it is there. I don’t want to dissolve because I am too scared. Can PRF help to this situation? Thank you so much for your informative videos!

[@AmiyaPrasadMD]

Hi Hadar herchkovich, Assuming the malar edema was caused filler treatment, the logical step would be to dissolve the filler, then allow the edema to heal. I would have to examine your face before making more specific recommendations, so I suggest you follow up with the doctor who performed the filler treatment for a proper examination so they can recommend treatment. I hope this helps you.

[@JaxDianne]

Great Explanation

[@AmiyaPrasadMD]

Thank you, Jax. I'm glad you found the video informative.

[@andybaubau5961]

hi, talking about ha skinboosters, how do you compare prp prf to skinbooster resuts? are similar or ha skinbooster give much better satisfaction? prf give better result than prp? thanks

[@AmiyaPrasadMD]

Hi Francesco Dedona, It's not a question of which treatment is better than the other, it's a question about which treatment is best for a particular issue, and best for an individual patient. PRP is still the base material in both PRF, and in Skin Boosting, but PRF is more refined and concentrated, and Skin Boosting is not as deep into the skin. I hope this clarifies things for you.

[@bartender4877]

Do you preform the fillers placement the same day as the prf / prp? And what’s the best filler for undereyes?

[@AmiyaPrasadMD]

Hi @bartender4877, Yes, under eye filler can be done at the same time as PRP, or PRF because there is a synergistic effect for volume, and skin quality improvement, and combining the materials can extend the effective life of both treatments. Placement technique determines results more than the brand of filler. You can refer to this video about it - kzbin.info/www/bejne/nKi3c3affKyEqZY

[@Dunstlookalike]

May I ask how long the PRF effects last? Thank you !

[@AmiyaPrasadMD]

Hi @Dunstlookalike, As explained in the video, PRF improves the skin health and quality from within, so the effects don't fade like a filler, and results can be built on with subsequent treatments. That said, PRF or PRP don't stop the effects of aging, or sun damage on the skin. As for the volume effect of PRF, it only lasts about 3 weeks. I hope this clarifies things for you.

[@tornjordans5445]

awesome video Dr! about how soon after getting prfm under the eyes could i safely get fillers? also, would you suggest prfm + filler or ez gel to get a lasting volume effect?

[@AmiyaPrasadMD]

Hi @tornjordans5445, I often perform filler treatment at the same time as PRP or PRF, and hyaluronic acid fillers do have a synergistic effect with PRP or PRF, with patient examples shown in the video (and both patients featured in the thumbnail). The volume effect of softer hyaluronic acid fillers used under the eyes last about a year, while the volume of EZ Gel only lasts about 3 months. I don't use EZ Gel in my practice. I hope this clarifies things for you.

[@ruqaiyah2950]

Can you please doctor talk about onda body contouring is it really effective

[@AmiyaPrasadMD]

Hi Ruqaiya H, It’s important to remember that the particular device does not determine results, or causes complications, but rather the experience and judgment of the doctor using the device. The device is just a tool, and it’s the doctor’s judgment using the tool that separates great results from ineffectiveness, or potential complications. You can refer to this video about it - kzbin.info/www/bejne/oYvYq2aGpLmcZqs

[@VitaminCici]

Hey Dr. Prasad, I see PRP treatment for hair lost , is there any chance can use PRP from eyebrows grow ? I know people hair transplant to eyebrows , let's say not everyone want to moves hair they already have. does PRP work for eyebrows ? Thank you

[@AmiyaPrasadMD]

Hi @VitaminCici, I don't administer PRP alone for hair loss as effects are limited, and many treatment sessions are required. However, our TrichoStem Hair Regeneration treatment with extracellular matrix by ACell as the main ingredient, and PRP as the activator has been used to thicken eyebrow hair. While eyebrows are not featured in the video, you can refer to this video about how our treatment works to thicken thinning hair - kzbin.info/www/bejne/lZDbh4dnqMt0l5Y

[@choubeila2996]

Doctor I have dark hallow under eyes, can I get both prf for skin quality and ez gel for volume if so how much time it takes so the ez gel dissolve ?? (I got filler before but I didn’t like resultes after a while cause it immegrates so I had to dissolve it)

[@AmiyaPrasadMD]

Hi @choubeila2996, The volume effect of EZ Gel would only last about 3 months, and volume of effect of PRF would only last about 3 weeks, while filler should last about a year. It's important to remember that results of filler, or migration of filler are mostly due to the technique of the doctor injecting it, not the material itself. If you had trouble with filler migrating in the past, then you need to see a doctor with better filler placement technique. I just made a video about it, for your reference - kzbin.info/www/bejne/o6K1pKeYgciWhZY

[@lashannawilliams5707]

hi doctor i’ve had under eye filler done about 3 times and i want to get ez gel injected with a cannula, i went to a aesthetician and she said due to having filler previously i couldn’t get this done is that true?

[@AmiyaPrasadMD]

Hi @lashannawilliams5707, It's not clear if the filler is still there. PRF/EZ Gel only provides short-term volume. If the volume from filler is still there, it would be better to have regular PRP instead to improve skin quality, and skin thickness, without having the appearance of too much volume. I hope this clarifies things for you.

[@lashannawilliams5707]

@@AmiyaPrasadMD Thank you doctor

[@AmiyaPrasadMD]

You're welcome, @@lashannawilliams5707

[@nzzimi]

Do you like sculptra under the eyes and for nasiolabial folds?

[@AmiyaPrasadMD]

Hi Niko Paz, Since Sculptra uses a biological reaction for the body to create its own volume, the results are not as predictable or precise as hyaluronic acid fillers. You can see the results under the eyes in this video, and can refer to these other videos to see how I treat nasolabial folds with hyaluronic acid fillers: kzbin.info/www/bejne/eGKsc5WHfZh7d7M kzbin.info/www/bejne/qHTNpoh3pMt4fLc

[@rb9198]

My eyes fillers are sowllen after facial prp . Is this normal or should i visit doctor?

[@AmiyaPrasadMD]

Hi RB🦋 , Yes, you should see a doctor. While some temporary inflammation is expected after PRP treatment due to trauma, significant swelling can be a potential issue, and should be properly diagnosed by a doctor to determine the cause. I hope can see a doctor as soon as possible for a diagnosis.

[@kiramiftari9486]

Dr PARSAD, what do you think of the EZ GEL? Is it more expensive than PRF and is it worth it? thnx;-))

[@AmiyaPrasadMD]

Hi @kiramiftari9486, EZ Gel is basically PRF, which still does not provide a lasting volume effect that can replace hyaluronic acid fillers. I hope this clarifies things for you.

[@milenagevorkian-eu2qi]

Hi Dr. Prasad! I have a really important question for you, in terms of hair loss, what is the different between prp and prf!? Does PRF include ECM? Please help!

[@AmiyaPrasadMD]

Hi Milena Gevorkian, PRF is a refined form of PRP. PRF does contain ECM as it's a separate material, and ECM is not derived from the human body. ECM is the main ingredient of our TrichoStem Hair Regeneration treatment, with PRP used as the activator of ECM. You can refer to these videos about the differences for our treatment from PRP/PRF alone, the differences of our treatment versus other treatments using ECM, and how are treatment is used to treat female pattern hair loss: kzbin.info/www/bejne/rIukeJR3qNiYrbs kzbin.info/www/bejne/b5m9g6log7Zqia8 kzbin.info/www/bejne/aIjLdn-vmtB6aqM

[@milenagevorkian-eu2qi]

@@AmiyaPrasadMD Thank you! I appreciate it!

[@AmiyaPrasadMD]

You're welcome,@@milenagevorkian-eu2qi

[@NinorahDeux]

Hello and thank you for your very informative videos ! I wanted to know if prp could work on thighs skin for example, when it's a little bit crepey and loose (but no excess of skin at all: just a problem of texture): can it tighten the skin ?

[@AmiyaPrasadMD]

Hi @NinorahDeux, Loose thigh skin is often treated with a laser to tighten, and tone the skin. What I often do is alternate PRP between laser treatments to still induce collagen, but also reduce exposure to heat. PRP alone may not be enough to get the results you want, so you can consider alternate treatments as well like thermal skin tightening. I hope this clarifies things for you.

[@NinorahDeux]

Thank you very much ! But i confess i'm too afraid of thermal treatments, as i read many scaring reviews: i'm skinny already so i want to keep my fat to any price :D @@AmiyaPrasadMD

[@AmiyaPrasadMD]

Hi@@NinorahDeux, Your apprehension is understandable, but it’s important to understand that results, or complications are determined by the judgment, experience, and skill of the doctor or practitioner using the device, not the device itself. You can refer to this video about it - kzbin.info/www/bejne/oYvYq2aGpLmcZqs

[@NinorahDeux]

Thank you very much for those informations ! I will reconsider laser now.@@AmiyaPrasadMD

[@AmiyaPrasadMD]

You're welcome,@@NinorahDeux. With laser and other treatments, just make sure you are with an experienced doctor. If you have darker ethnic skin, a radiofrequency treatment may be better to prevent hyperpigmentation. Best of luck with your treatment!

[@ffidsalelowprice6066]

Can I expect regrowth in hairline after using finastride

[@AmiyaPrasadMD]

Hi FF ID Sale low price, Finasteride is primarily for slowing hair thinning, but some men may get some hair growth, depending on their level of DHT-sensitivity. Men with high DHT-sensitivity often don't see the results of finasteride, but the result is slowing their hair loss progression which would be faster and more aggressive without it. I hope this clarifies things for you.

[@ffidsalelowprice6066]

@@AmiyaPrasadMD thanks doctor for precious time 1 more questions why u give reply to everyone without any money

[@AmiyaPrasadMD]

Hi@@ffidsalelowprice6066, If you'd like a diagnosis of your condition, as well as recommendations for treatment, you would need to pay a consultation fee. I hope this clarifies things for you.

[@kelljA]

Would you use a mix of restalyne and PRF?

[@AmiyaPrasadMD]

Hi @kelljA, Yes, the results featured on the video thumbnail feature a mix of Restylane and PRP to improve volume, skin quality, and to also extend the effective life of both materials. I hope this clarifies things for you.

[@Kirmukarmu]

Hi Amiya, @@AmiyaPrasadMD But restylane is really expensive compared to the amount injected. Restyle didn't work for me because the amount injected is so so so little.

[@AmiyaPrasadMD]

Hi@@Kirmukarmu, I see my patients again two weeks after filler treatment to see how the material has settled, and if a little more enhancement is needed. If too little was applied, then your doctor can apply more, if it is still within your budget. It is better to be conservative at first, and add a little more later if needed, than to use too much, and have to dissolve it all, and start all over again. This is a less costly approach as it uses less filler material, as well as the extra procedure to dissolve filler. I hope this clarifies things for you.

[@BlessedLife291]

Great explanation

[@AmiyaPrasadMD]

Thank you, @BlessedLife291. I'm glad the video answered your previous question.

[@sudiptagore5809]

Sir I'm from Nepal and I have dark circles since 4 years I use so many creams while I used those creams my dark circles got reduced for a sometimes but when I stop using my dark circles again appears I tired😢😢😢😢 my mom had this but expect her no one has dark circles how can I reduce this

[@AmiyaPrasadMD]

Hi Sudip Tagore, Sorry to hear about your problem. While a physical examination is needed before making specific recommendations for you, these videos feature the ways I treat under eye dark circles in my practice: kzbin.info/www/bejne/h3PZm52srbWnaMk kzbin.info/www/bejne/iWfCn4eIp5ann9E kzbin.info/www/bejne/oIK4k2lth9WUd68 kzbin.info/www/bejne/iHmtoJeYaZhqpZY

[@daliaaroundtheworld2213]

Hey doctor do you come to Dubai?

[@AmiyaPrasadMD]

Hi Dalia Around the world, Sorry, I only practice in the East Coast of the US as I can better care for my patients without so much time spent traveling.

[@charanpreet7748]

Love this video 💗 I have the question in march 2022 i had done with my ptosis surgery but still i have problem that my one eye is half open while sleeping and sometimes the operated eye looks more open and the other eye looks droopy please can you guide me ??🥺🥺i am very disappointed Sorry for the wrong english🥺 I hope you replied❤️❤️

[@AmiyaPrasadMD]

Hi Charan Preet, Sorry to hear about your problem. It may be a little late since you had the surgery over a year ago, but you should have followed up with your surgeon soon after surgery. Any surgeon experienced in ptosis surgery knows that additional enhancement is sometimes needed because it is such a precise surgery. Your surgeon should have a revision policy in place for eyelid ptosis correction as it is the nature of this surgery to sometimes need further work soon after healing. Since it has been some time since your surgery, you may require another surgery for further correction. I hope this helps you.

[@charanpreet7748]

@@AmiyaPrasadMD but my doctor said that there is no need of revision surgery as the measurement of eyes are same

[@AmiyaPrasadMD]

Hi@@charanpreet7748, OK, but I can't provide you any more guidance unless you come in for a physical evaluation so I can make a proper second opinion. I hope you understand.

[@pedro_ferreirinha]

First of all, congrats for your channel and content! To lighten dark circles and improve skin quality, do you prefer PRP or PRF? Regards from Portugal!

[@AmiyaPrasadMD]

Hi @pedro_ferreirinha, Either can be used, depending on the patient. PRP or PRF can be combined with other modalities such as laser or radiofrequency for further treatment of discoloration, and added collagen stimulation. While a physical examination is needed before making specific recommendations for you, these videos feature the ways I treat under eye dark circles in my practice: kzbin.info/www/bejne/h3PZm52srbWnaMk kzbin.info/www/bejne/iWfCn4eIp5ann9E kzbin.info/www/bejne/oIK4k2lth9WUd68 kzbin.info/www/bejne/iHmtoJeYaZhqpZY

[@mokar0873]

PRF won't replace HA, however it is much better then PRP

[@AmiyaPrasadMD]

Hi @mokar0873, It depends on the situation as PRF is not a replacement for PRP in all situations, and PRF is still PRP. PRF is used in situations when slower release of wound healing, and growth factors are needed. PRF can't mix as well as PRP with extracellular matrix by ACell which we use in our TrichoStem Hair Regeneration treatment. I hope this clarifies things for you.

[@Kimberlysalchemy]

Filler migrates and causes major swelling issues for many people. I think nanofat is a much better solution than filler.

[@AmiyaPrasadMD]

Hi @Kimberlysalchemy, Fat grafting under thin lower eyelid skin is highly prone to complications. I know this because doctors who recommend and perform the procedure can't remove the grafted fat when complications occur, so their patients end up seeing an eyelid specialist like me to surgically remove it. You can refer to these videos about it: kzbin.info/www/bejne/o3_SkHh4mKmcZ80 kzbin.info/www/bejne/iXeUgGCqhbt6hZI

[@estelled389]

I don't want toxic plastic fillers they are so out now . Moving to better safer technologies

[@AmiyaPrasadMD]

Hi @estelled389, I only use hyaluronic acid fillers, and hyaluronic acid is naturally present and produced by the body to lubricate joints, and retain moisture in the skin, so hyaluronic acid is the safer technology. I don't recommend or administer PMMA (polymethyl-methacrylate) fillers, or "plastic" filler as you describe, but I have removed it for patients when they were placed by other doctors. You can refer to this video about it - kzbin.info/www/bejne/eYutYWion8apadU

[@FB-im7zb]

Thank you 👏🏼

[@AmiyaPrasadMD]

You're welcome, F B. I'm glad you found the video helpful.