You Can Inherit Mitochondrial DNA from Both Parents! | SciShow News

Earlier this week, a team of researchers announced that they’d made a discovery about how we inherit mitochondrial DNA from our parents that could change what we know about not only disease inheritance, but human history as a whole.
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Sources:
www.pnas.org/cgi/doi/10.1073/p...
ghr.nlm.nih.gov/primer/basics...
ghr.nlm.nih.gov/mitochondrial...
hihg.med.miami.edu/code/http/m...
www.zmescience.com/other/scie...
www.scientificamerican.com/ar...
www.sciencedirect.com/topics/...
www.pbs.org/wgbh/nova/article...
www.mitoaction.org/guide/the-d...
www.sciencedirect.com/science...
www2.palomar.edu/anthro/homo2...

[@The_Viscount]

The more I learn, the more I realize I have yet to learn.

[@ccharms60]

Yes so true you spoke what I was thinking but before I read your comment I didn't have the words👍😍

[@johnhester2780]

May your cup never be full

[@glennfrick7975]

👍

[@rednarok]

only when you think your dumb is when you start becoming wise. the wisest people always doubt their knowledge.

[@joseberger7737]

this perfectly explains the dunning Kruger effect

[@veranet99]

I think its fascinating that there's a mechanism to kill the paternal mitochondrial DNA. I wonder what the evolutionary pressure for that would be.

[@pedrolmlkzk]

having too many mitochondrias and having two sets of it making it more likely to break down?

[@veranet99]

@deharleyva thank you.

[@Ratchet4647]

Likely that in the streamlining of sperm so that it can find an ovum the presence of mitochondria is an unnecessary expenditure. Thus, a mutation that killed off mitochondria in sperm would get passed down.

[@federook78]

Well, you're seeing what happens when it doesn't work... The whole story is BASED on mitochondrial disorders

[@mjade1673]

@@federook78 right

[@amandac.s.9452]

As a true crime nerd who used to major in forensic science before switching to criminology, this absolutely terrifies me!

[@c0ldNcl34r]

Amanda C.S. oh dang, yeah, this might put into question a LOT of dna evidence. This is absolutely huge

[@martinicc67]

@@c0ldNcl34r Probably not since the likelihood of someone having this disorder is pretty small. Though it would put to question everyone suspected or acquitted of a crime who has someone with a mitochondrial disorder in their family.

[@briansammond7801]

@martinicc67 But there is nothing to say that someone has to have this disorder in order to have inherited mitochondrial DNA from the father. It just so happened that the presence of the disorder is what led them to make the discovery.

[@jackielinde7568]

You think this is bad, what do you think every prosecutor is doing right now when they hear this. Only other place I wouldn't want to be is an executive of a company like Ansestry.com or 23 and Me.

[@chevychase3103]

Does that mean my cousin did it in the library with a candlestick?

[@gubjorggisladottir3525]

Well this does seem to be limited to people with mitochondrial DNA disorders... those disorders are possible only because some of the "sperm mitochondrial DNA" survived the "mitochondrial-killing mechanism" and became part of the egg that the person developed in.

[@dropmelon]

Guðbjörg Gísladóttir What if the reason for it to seemingly appear only in patients with mitochondrial DNA is because most healthy people don’t sequence their genome?

[@absalomdraconis]

@@dropmelon : It seems likely. I would even suspect that it wasn't necessarily a Nuclear DNA mutation, but possibly an Epigenetic mutation instead.

[@albertnortononymous9020]

@@dropmelon 😂😂😂I’m dying

[@FreediiFree]

Wait, this is like...a big deal...Like this could change a whole lot of how we see the history of humanity. oh my.

[@FreediiFree]

or its a one off...but still

[@Luminarada80]

Mitochondrial DNA is kind of limiting, luckily a lot of the recent research into ancient DNA has been using full genome sequencing to look at our history. So while this might throw off some of the science, a lot of it will not be affected. Also, I am not sure if the statistics of the tests will be thrown off a lot by a 1/5000 degree of error, but if the results rely on the assumption that the mitochondria is strictly maternal then the data will need to be reviewed to make sure that it is still accurate.

[@maracachucho8701]

1 in 5000 doesn't sound like a big deal to me

[@huldu]

100 year from now everything will be different. That's just how things works. Never assume anything. They're going to look back at "us" and have a laugh at how savage we were at treating something like cancer. You live one day, you're dead the next and that's it.

[@illumnis]

Not really.. not unless it can be demonstrated to be widespread. Like many new findings, the study he talks about doesn't quantify the phenomenon, only documents it. Three families decidedly *not* selected at random do not statistics make.

[@stephaniesummer2663]

Then what will happen to Mitochondrial Eve? Edit: Thanks for the likes. I didn’t think it was that funny

[@Master_Therion]

Perhaps there's a Mitochondrial Steve??

[@eve36368]

Master Therion *sips cup of tea* what a great day to remember bisexuality exists as well as intersex people & that these are not related except for the struggle against sexism

[@stephaniesummer2663]

Master Therion That’s good.

[@dpeYoutube]

@@eve36368 what does this have to do with the mitochondrial eve. That's an actual think in genetics. Also, regardless of anyone's stance on sexuality, and gender. A biological man, and biological female has been needed for humans (and their ancestors) to prorate for a few quite a long period of time.

[@Dabuddah]

Literally nothing. She's been dead for a LONG time

[@Master_Therion]

Wow! They survive the "mitochondrial-killing mechanism?" 4:51 Those are some... mighty-chondria.

[@wiltedlamp5016]

I mean... it is the powerhouse of the cell.

[@Hadkek]

😉😉😉

[@snm359]

Just read your Mitochondrial Steve comment, keep up the good work.

[@cathacorrigan5782]

@@snm359 right and I like big butt's and I cannot lie

[@Master_Therion]

@@qpixel5827 True, true. I might change it to "Those are some..." More people are familiar with the plural form mitochondria.

[@SpazzyMcGee1337]

This is a big paradigm shift as far as news goes.

[@siriuslee9615]

That makes EVERYTHING more complicated . Amazing ❗️thank you good information .

[@justbreathe7816]

Time to change the biology book

[@faramund9865]

So in most cases it does come from the mama, but there is 1 in 5000 chance that it comes from both?

[@ash1rose]

This could be huge. It seems as though the majority of people inherit all of their mitochondria from their mothers, but if it's possible for paternal inheritance, it raises a lot of questions. Even though it's obviously far too early to say anything conclusive, this is something I'll be watching out for.

[@nikkib8811]

Fascinating. It just shows how much we don't know and how there is so much yet to know. Exciting times. Clearly explained on video.

[@bjusticetube]

Great episode. Well written. Keep it up yo.

[@magister343]

One of my best friends is a researcher who works with mitochondria, using CRSPR to knock out genes and find out what each protein does. She had not heard this news yet until I showed the video, even though it could definitely be relevant to her research.

[@kevinportillo1971]

Finally a video that does not summaries an online headline in a 2 mins video.

[@madmonkee6757]

I've always wondered why/how we don't (normally) inherit mitochondria from our fathers. The sperm contains at least one mitochondrion (in the midsection) and it enters the egg.

[@evilferris]

Holy Crap! **This is a big deal.**

[@MrBranboom]

If mitochondrial density is similar between sperm and egg then there is something like 15,000x more egg mitochondrial organelles then sperm mitochondrial organelles. Makes sense that a few would slip though. Also, the sperm mitochondrial organelles would be distributed across the body in a similar stripped pattern that is seen with a females XX chromosomes. So it is possible that the many times the sample that is taken from the individual may not represent the individuals genetic make up as the sample does not accurately represent the whole. DNA samples should be matched by type. Eyelash for eyelash ect.

[@gnarthdarkanen7464]

I have to wonder if there isn't something to a weird "coincidence" by which we've only been able to DETECT mtDNA inheritance from the Maternal side... Perhaps, EVERYONE inherits some mtDNA from both parents, and for whatever reason, we've only sequenced enough to notice the Maternal... Possibly just because of an imbalance between the two that has to do with spending our first nine months of development INSIDE our mothers... or some related tangent. If (in fact) there's a certain inheritance of mtDNA from Fathers, just a lesser over-all quantity... something machines could possibly "dismiss", then there's a WHOLE LOT of re-writing on the matter to contend with before we go out with predictions and suppositions about the "actual historical tracing of humanity"... Likely as not, it's not going to change a LOT... The general patterns of geographic spread will likely remain relatively similar (or the same) and only the amount of time (numbers of generations) will really change... It's just that little detail is going to have to be re-written into every lineage and direction... so a LOT of re-writing by volume. ;o)

[@MrBranboom]

@@gnarthdarkanen7464 It's probably a genetic adaptation to limit mutation/innovation in such a fundimental aspect of our biology. But, it may be advantageous to have some room for variation. Interesting to think about anyways.

[@jonathanodude6660]

@@gnarthdarkanen7464 dna is dna, if you amplify it youre going to see a lot of anything currently there. it would be noticeable. also the placenta stops cells from the mother entering the baby so theres no way mitochondria would get through.

[@gnarthdarkanen7464]

@@jonathanodude6660, if you paid attention to the vid'... We're still very much in the "entirely theoretical stage" of things with this "new information"... Frankly, they need a MUCH bigger model/sample source to make much out of it other than "anomalies are anomalous"... Now, all that said... I didn't intend to suggest that any further DNA had to enter the baby from the mother... Look at the slightly larger picture... By nature of the baby developing in the mother, maternal DNA would have a defacto "home court advantage"... AND this "paternal DNA kill-off" might be nothing more significant than immunity protections of the mother working around the womb. The sad fact is, there's still a LOT about gestation and childbirth that we just don't understand in its entirety... I'm only suggesting that it's possible that we ALL have some miniscule portion of Paternal mtDNA in some residual form... It just hasn't been "detected officially" as of yet. Sure... dna is dna... BUT EVERYTHING done with DNA sequencing is a "Statistical Modeling" function... When you deal with statistics, the Over-riding protocols "follow the curves" and "dismiss outlyers"... That hasn't changed in scientific circles in more than a couple centuries... AND some of it gets a bad name to statistics in general, particularly when people get TOO enthusiastic to argue, and start "cherry picking" results to fit their "curve agenda" instead of acknowledging "noisy curves" where there are more than a very few "outlyers"... Okay, so I'll give you that I'm not a premier geneticist making a career out of glow-in-the-dark rats, or spiders secreting wool instead of silk... fine. Just take a moment, think about it. These DNA sequencing "systems" have been rigorously tested and peer reviewed, but by peers who ALSO dismiss "outlyers" to follow "curves" in their own statistical models... often calling those outlyers "noise" when the models are clusters and curves of data numbering into the billions (you know, like individual bits of data from a strand of DNA?)... How fun and interesting would it be (and what a strange new step in scientific data assemblies) to now ABSOLUTELY HAVE to chart and acknowledge just how much "statistical noise" had to be "dismissed" for a study to become "technically viable"??? We're not talking about amplifying a DNA sample with a 50/50 mix of "Mom and Pop" but more like a "99.98/ 0.02" mix... See the difference? Suddenly "Pop's contribution" gets amplified into a speck or two of "wtf is that" while Mom's consistently shows up with flying colors. You and I would probably have no problem "shrugging it off" as noise, either... ...Just hoping to clarify... ;o)

[@diegocolomes]

@@gnarthdarkanen7464 really nice point, I feel it's the same problem almost everywhere in science, the primacy of the model over the actual reality (not always an easy problem to resolve), for instance in economics, demography, climate science, even in astronomy (lots of problems with the Big Bang model and its suppositions and predictions) and so on.

[@SadhviJenn]

I was just wondering about this today. :)

[@yourfuturedocburenbeiya]

Nice! I wonder if there are new update to these studies.

[@rejvaik00]

This is why I sub to your channel well done sci show

[@Rhioah]

THIS CHANGES EVERYTHING!!!

[@SadhviJenn]

Fascinating.

[@yoursotruly]

Mitochondrial patricide! There is always an exception to prove the rule, 1 in 5000 is just a blip in the statistics so this is interesting but changes little about the general conclusions.

[@craigme2583]

Oh i could watch you all day...

[@00EvanG]

That could be worthy of a Nobel Prize.

[@aaronedvalson104]

Makes me wonder if the Rh factor could be implicated in whether the father's mitochondria is killed off or not. Like an immune system triggered event.

[@darkhorseman8263]

This is a good thing. It means one parent with healthier mitochondria can help overcome another parents with damaged mitochondria through natural mito-fusion and fission protofection mechanisms. This is the key link in how parabiosis works. It isn't just replenishment of GHK-CU or GDF/BMP11, but naturally occurring protofection of younger mitochondria with less mtdna mutations.

[@absalomdraconis]

@@osmosisjones4912 : Because if only the mother contributes mitochondrial DNA then the analysis gets easier.

[@gnarthdarkanen7464]

It's certainly possible... BUT it's also possible that we've been "dismissing" residual Paternal mtDNA... stick with me a moment... We start development for nine months INSIDE our mothers... As a result, there's probably some basic necessity that would protect more of her mtDNA... AND less of the paternal (by rote)... If there's some imbalanced but present quotient of both parents present in mtDNA in everyone, then the machines so finely calibrated in the earlier days of mtDNA research were "accidentally" dismissing miniscule particles of Paternal mtDNA from samples as "noise"... OR it was just getting overlooked in the processing. It's amazing how much data gets declared "garbage" in statistical modelling... SO there is the possibility here. SO if that's the case, there doesn't have to be a specifically anti-paternal mtDNA mechanism to be over-ridden. The normal chemical balances inside a mother's body would inherently add to her concentrations of mtDNA in the offspring that spends time inside her, while the father's only contribution is from the original sperm... Samples with this imbalance might not even have enough to "register" in the normal methods of processing and sequencing, and could be lost... up until someone was curious enough to finally end up with the "statistical anomaly"... In any case... now we wait. More research and development needs done... ;o)

[@joecurran2811]

It never made sense to me that you could you only inherit mitochrondria from the mother. This makes sense.

[@darkhorseman8263]

It is s possibility that is why Parabiosis works so well. Wasn't just GHK-CU, Osteopontin, and BMP11 in young blood. Its could be younger mitochondria in the white blood cells.

[@sousaphonist]

So what I understood from this is that they discovered evidence in three separate families, each with suspected or confirmed mitochondrial disorders, that some mitochondrial DNA came from paternal lineage and not just maternal. It is also theorized that, during ovum fertilization, mitochondrial DNA carried by the sperm cell is usually wiped away, so the previous observation may be due to the "wipe the slate" step being skipped. Given all this, theory: is it possible that certain mitochondrial disorders occur BECAUSE the "wipe the slate" step gets skipped? Think about it; the addition, deletion, or alteration of genes is well-known for causing a whole variety of conditions, so isn't it at least conceivable that an error during fertilization which directly affects the fetus' DNA could cause such disorders?

[@aeriumsoft]

The mitochondria is the powerhouse of the cell. i bet 100 comments have said this already

[@magisterrleth3129]

WHAT?! This is incredible!

[@conniecrawford5231]

Good info to know ! This should be helpful in future health- and even crime -cases!

[@catherinayoung]

That was awesome

[@just-a-silly-goofy-guy]

Say it with me *_the mitochondria is the powerhouse of the cell_*

[@MungusBeans]

Da

[@ssalamander2134]

*the mitochondria is the powerhouse of the cell*

[@drazgul9403]

Biology class flashbacks

[@josiahklein70]

*mitochondrion or *are the powerhouses

[@bbbb95476]

*mitochondrion

[@mildlyacidic]

Damn that makes things a lot more complicated

[@MCC4RTHY1]

Brilliant

[@BoDiddly]

From my understanding, this has been seen many times before, but when scientists find this type of DNA, they typically throw out the results, assuming that there was an error in the process.

[@hosoiarchives4858]

Lol

[@mannyespinola]

Innnnnteresting!

[@celtgunn9775]

This is fascinating Hank! Can you guys please do a deeper investigation into Fibromyalgia and how it affects people who have it? You see, I've had Fibromyalgia for 15 years now and the Doctors ~still~ haven't gotten a treatment plan down pat for me. 😕 Pain is a daily routine for people like me.

[@avalonunitygarden2394]

Possibly take Vit. B & seams worse when the person is depressed. It’s the nerves at wits end.

[@manny2248]

Ayo the man got a noble prize for his research

[@normalname8768]

well this changes everything. I was just watching pbs eons about where humans came from using mitochondrial dna.

[@einsteinwasright1044]

Clinically, most human mitochondrial disorders are caused by abnormal NUCLEAR genes, which are inherited in the usual manner. Also, most mitochondrial enzyme complexes are made of multiple subunits, most of which come from nuclear genes. So even when a defective mitochondrial enzyme exists that does contain one or more subunits that come from mitochondrial genes, it isn't necessarily the case that the mitochondrial genes are the ones that are defective. This is complicated to work out in each family.

[@jaimie00]

Wow!

[@TallBison]

This has the potential to change everything. cool.

[@AchiParadkar]

Did anyone observe that Hank has started to talk a bit more slowly for us?... Thanks Hank!

[@rivitraven]

This will definitely change forensic science and how mitochondrial dna can be used to link dead people that can't be visually identified to their families. This will make it harder to do so because of such sequenced patterns being changed to something that is different from siblings or mothers yet in nuclear dna they show up as similar.

[@johnsnow5305]

This definitely could rewrite our ancient history book. It seems that this is a rare event, but even so, it adds up over time. I was confused about mDNA inheritance when I learned about it, because my understanding was that the code for mDNA is actually inside the nucleus, with the rest of our DNA. If that were the case, shouldn't the sperm's haploid DNA also have a chance of containing mDNA? If that were the case, what happened if it did, and the egg obviously does as well? Anyways, this is something we're going to have to re-examine.

[@danielshawl2850]

Glasses looking real slick

[@morbly]

Uh oh! We'll have to rethink that whole kwisatz haderach thing!

[@Jarrodmontelius]

Current science knows all! It just changes every month...

[@amanatee27]

Awesome video, thanks SciShow! :D

[@raghavrokr]

THIS IS GROUND BREAKING!

[@____o____279]

Thanks SciShow. I love your Videos ❤️❤️👍👍👍👍

[@TrueCrimeWithEve]

is there any update on this research?

[@lyn3325]

But like, what do I put on my multiple choice final when I take it later if the textbook still said it is inherited from the mother? (At least, that is what I think I remember) I'm not sure what is accurate for test scores now...

[@harrietharlow9929]

Interesting. I have long thought this might be a possibility. I got told I was daft, but the idea stayed with me.

[@Toastmaster_5000]

As much as it's great for science to disprove commonly held beliefs and pushes things forward, this is one of those cases where the error is especially disastrous. This really throws a wrench in forensics and mapping the human genome, as well as historic records.

[@starventure]

Peter Schmidt Not really. This is an isolated case, and a fishy one at that. The overwhelming part of the human population has received their Mt dna from their mothers and no one else. I strongly suspect that there is more to this particular case than they know about yet. If they find multiple cases of inbreeding in the boys past ancestors, then the inheritance rules still stand except for the freaks out there.

[@lvdart]

The familial component would make a lot of sense. It shouldn't have taken so long to uncover more evidence of this if it was more common than 1/5000, or if it is strictly familial.

[@lewisrainwater9527]

Kid had great grandparents alive who could do genetic testing? Lucky

[@maybr]

WOW!!!!

[@juiciegiraffe2562]

this is nobel prize winning!!

[@artemishli]

This is amazing news! Sure it hasn't been studied much yet but it's life changing! ( Ha, life changing )

[@christelheadington1136]

I've already been through "change of life",don't wanna go through that again.

[@CarbonKnights]

It's just a matter of time before Aya Brea is going to have to save us all from our Mitochondria...

[@IHS333]

This is cray cray

[@DicerX]

This is a pretty heavy blow to the accuracy of mtDNA ancestry studies and services.

[@finalfrontier001]

why? this is diseases not DNA inheritance. That can only come from the father as the sperm is created by the male.

[@lifesacardgame6454]

Wow.

[@BaronVonQuiply]

Well... this changes things.

[@electronicsNmore]

The key to long life? Good DNA with a large gene pool. You can eat healthy as possible, avoid smoking, drinking, toxins, but if the gene pool is bad, you're toast.

[@starventure]

electronicsNmore Inbreeding does a body bad...

[@electronicsNmore]

@Xero [2] Disagree completely.

[@NonDelusional74611]

😬

[@mrlloyd149]

sources: dude trust me

[@TylerBevanOfficial]

Xero [2] is right on this. Genetic mutations can be “turned off” or just not manifest themselves physically if the environmental factors are just right

[@BitterMonday]

I need update!

[@keriezy]

This whole video is one big goosebump! Freaking fascinating!!!!!

[@einsteinwasright1044]

Hank stated that the mitochondrial mutation rate is slow, but that rate is certainly faster than the NUCLEAR gene mutation rate because the mitochondrial gene duplication enzymes lack error checking / repair mechanisms, and mitochondria lack the enzymes required to repair environmental and free radical DNA damage (referring to free radicals that escape the mitochondrial defences such as superoxide dismutase). Mitochondrial replication is regulated by the amount of energy produced as ATP, so mitochondria that inefficiently produce ATP tend to multiply more, increasing their proportion during the individual's lifetime, often causing symptoms and signs of disease to appear later in adult life rather than early in childhood, and mitochondrial diseases tend to get worse with each child born to a woman and with each generation because the "bad" mitochondria multiply more in the female reproductive tissues.

[@mikechaotix]

So does this mean my haplogroup is wrong? Oh god, who am I even!?

[@griggsentertainment6463]

Because the 4 year old boy was tested in "1983" (CRS) The older man in 2002 was the same person.

[@SlyPearTree]

It's an exiting time for science lovers who aren't scientists, we learn of new developments almost as they happen. Before the web we had to rely on science popularization magazines who only came out once a month and had limited space to show what was new, specially since a lot of what is new is disproved soon enough, remember cold fusion? Now the obstacles to share new discoveries have come down, and if something goes against what most people know then it's meat for a new show or article that can appear fast enough without too much angst from an editor or publisher. I think I understood that science was a process before the internet but now I can almost taste it. I'm now thinking that I would like a documentary on cold fusion from its discovery to its debunking, but the documentary would consist of youtube type episodes. "The great war" followed WW1 week by week, imagine doing that for scientific research.

[@chevychase3103]

I see lots of info and theories but no specific use! Not to say these discoveries will not help in a hundred years!

[@dianaarrubla7331]

Does that mean that the mitochondrial eve might not be correct? Or is it too rare to have a major effect on that

[@Ulquiorra_..]

Well we don't know what impact this has yet. it needs to be studied more to find out

[@beth8775]

It needs more research, but I think mitochodrial Eve will hold up.

[@absalomdraconis]

Mitochondrial Eve came from a period of small and localized human population, so everyone was basically a distant cousin or something similar.

[@Yora21]

Could still exist, but the dating might be completely off.

[@seanwebb605]

What about horizontal gene transfer and RNA?

[@RangerRuby]

DNA is so weird and awesome! #PowerofScience!

[@ireallydontlikeemail]

Could it be that people with mitochondrial disorders are the only ones to have their father's mitochondria?

[@bjrockensock]

Perhaps this takes place during the formation of the placenta

[@Azzarinne]

This wasn't here the first time I checked my sub list. I watched a couple of videos, and came back to find this. I should watch a couple of videos at a time more often, if a new SciShow episode is the reward! XD

[@roguedogx]

So it must be some kind of error when the two cells merge.

[@sr2291]

Is that what can cause "extras" in the MTDNA?

[@ooDriveoo]

The mitochondia are the powerhouses of the cell...

[@RMoribayashi]

They should be required to tell you that Google/KZbin takes a cut of the membership fee. It doesn't get a cent from Patreon.

[@arminhillman7956]

I understand you can't fix this now, but you misspelled "Trickier" at 1:01. Just a heads up, though i'm sure i'm not the only person who caught it. Have a nice day!

[@heatherkaye8653]

haha coming out with something like this right before finals week. ...

[@haroldhenderson2824]

So, the mother has a defect that did not prevent the father's mDNA from being excluded OR his mDNA has found a way to avoid that. Will an excess number of mitochondria give the offspring "superpowers" or just increase their cancer risk?

[@codyclark908]

Hi, student studying Biomedical Engineering here. What does this discovery mean in terms of DNA alteration processes we have, like CRISPR for example. Does the ability to live off of both paternal and maternal mtDNA without major defects allow us to better design a cure for genetic mitochondrial diseases like ADOA? If that's the case, this is pretty big for blind people.

[@Luminarada80]

The only way that we would be able to change that is through genetic engineering of human fetuses, which is highly controversial and considered unethical at our present state of knowledge. Also, a more direct way to cure the disease would be to just remove the "bad" gene and replace it with a functioning allele. This wouldn't let you cure living humans with the disease, but may eventually be a way for women with ADOA to have children who can see.

[@AlchemistOfNirnroot]

Spotify needs to add Acid Rap by Chance.

[@limalicious]

That's interesting, because in DNA testing in my family, I solidly look like I have my mom's mRNA grouping. However, my grandfather likely was the one I inherited Ehlers Danlos Syndrome from. He was never formally diagnosed, but I know for absolute certain he could pop his knees out backwards just as badly as I can. No one on my mom's side of the family has hypermobility.

[@starventure]

Limey How is your eyesight and your grandfathers eyesight? I heard that Ehlers Danos could sometimes be responsible for more flexible corneal lenses, giving better vision.

[@MrBlitzpunk]

Power cell is the mitochondria of the house

[@FallenPasha]

While not known until now, wouldn't the default position be to that there are influences from both?

[@0Clewi0]

no, because as the video explained there's a mechanism active in most cases that destroys the sperm mitochondria.

[@JNCressey]

Going far back enough in the science then sure. But then testing always showed people's mitochondria to be the same as their mother's. So then the default position was that you just get it from your mother, until evidence of it coming from a father was found.

[@criszis]

If it’s a passed on mutation causing this to happen, we might be able to find out it’s roots, and how common it was through ancient history

[@MilwaukeeAtheists]

the powerhouse of the cell?

[@marleigh5606]

Wait so what does this mean for mitochondrial eve?

[@LewBearMusic]

Daft question inspired by Futurama - how much power would it take to rocket Earth further away from the Sun to help keep us cool? And how far would we have to move the planet? Assuming we had to use rockets instead of robot farts

[@TKMcEachin]

Found this while researching for a fictional story involving DNA technology

[@lovewenwin]

Any updates ❓❓❓❓

[@Heyokasireniei468sxso]

i have some of my father's mitochondrial dna as does my siblings and my mother has from both parents , my father only has his mothers anyway i have both glad to see the truth is out there