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@yukuomen2259 3 күн бұрын
Very useful video！ The NSAID drug you mentioned in the video, is called "grappa print"? can you tell me the right name plz？
@clare-neurovet 2 күн бұрын
So glad you found it useful - Grapiprant - more info about NSAIDS here kzbin.info/www/bejne/kJSQnod-d6mFibs
@aashiarahman3640 6 күн бұрын
Hello doctor, thank you very much for this video. My dog, a 10 year 7 month old golden retriever, was treated with radiation therapy treatment (for brain meningioma) 4 months ago, and she has been on a mild dose of pregabalin 100 mg 2x 1 tablet daily (3 mg /kg twice daily) for the last 4 months. Recently, we observed a strange head twitching for half an hour; during this time, she was completely active and responsive. Could you please advise if it could be a side effect of pregabalin that showed as a myoclonus-type seizure? If Pregabalin is tapered down and eventually stopped, will it help her? The other anti-epileptic drug my dog takes is Levetiracetam 500 mg 3x 2 tablets daily. Please suggest. Thank you very much.
@clare-neurovet 5 күн бұрын
I am afraid that our Royal College of Veterinary Surgeons ethical guidelines (quite rightly) prevent me from making comments on medical management of patients that are not under my care so I can only refer you to your veterinary neurologist to discuss this. This because i cannot safely comment without knowing more about the dogs medical history. Yes pregabalin can very rarely be associated with movement disorders but there are many many other explanation including a benign idiopathic head tremor so speak to your vet. I wish you and her all the best
@cassiasantos2809 9 күн бұрын
Very good. Thanks ❤
@hansmjakobsen6865 22 күн бұрын
Thank you for an excellent presentation. I have a question. Are UC-II collagen supplements contradicted when a dog is on long term Pregabalin treatment? The literature does not seem to address that question. Thank you
@clare-neurovet 20 күн бұрын
I have not had any problems giving specific canine and feline joint collagen nutraceuticals (available in the UK )with pregabalin. obviously the ones that I advise for my clients in in the UK are ones that have a higher level of science to back them up (rather than ones intended for humans etc)
@hansmjakobsen6865 19 күн бұрын
@@clare-neurovetThank you so much, regards, Hans
@belencontreras6616 24 күн бұрын
Thank you, it was important for me to hear that cats liver does not filter as readily as dog livers. I will be mindful of that.
@user-ln3zk4nx1g 25 күн бұрын
My little Maltese just went for an MRI for a slipped disc & they discovered he has this 😢 hopefully picking him up later today.
@trinityveterinarybehaviour 26 күн бұрын
What an interesting case ! Thank you !
@rozenmaidens Ай бұрын
Very clear explanation thank you, helps me better how to manage as a person with a dog that has a spinal injury
@clare-neurovet Ай бұрын
glad you found it useful
@PoleiceCidcorn Ай бұрын
Brilliant thank you
@clare-neurovet Ай бұрын
thanks for your positive comment
@oatima Ай бұрын
This was a fascinating video, thank you!
@clare-neurovet Ай бұрын
thank you again for your kind comments! Yes - it is subject that I have wanted to tackle for a while and I don't think gets enough attention even in the specialist neurology and pain world
@trinityveterinarybehaviour Ай бұрын
Hello :), I just wanted to say thank you so much for these videos! I am currently studying for my Board exams in Veterinary Behaviour Medicine (American & European Colleges) and have loved watching and listening to your videos for some of the psychopharmacology and the neurology that I need to know !! Thanks again !!
@clare-neurovet Ай бұрын
thanks so much for positive comments! really appreciated. Check out the video that will be posted tomorrow morning - intended as learning tool for "headache" which is not a common subject in veterinary medicine (deazel's story)
@trinityveterinarybehaviour Ай бұрын
@@clare-neurovet ah just seen it! Excellent, I will definitely have a listen! Thank you, Katrin :)
@oludipeemmanuel9968 Ай бұрын
Fantastic delivery Prof. Had a couple of cases managed with Polypharmacy and Swimming hydrotherapy with excellent recovery process. I'm glad you clearly stated cage/crate rest should be well defined to Pet owners. With this i'm more confident to help Pets with IVDD and i hope to learn more from great tutors Like you in future. Thanks Once again Prof.
@clare-neurovet Ай бұрын
thank you so much for taking the time to comment - really delighted to hear about your outcomes I am so pleased that my lectures have improved your confidence because that is my mission (along with providing neurology resources to veterinary professionals that might have difficulty accessing good quality CPD and ultimately benefit the animals
@oludipeemmanuel9968 Ай бұрын
Fantastic delivery Prof. Had a couple of cases managed with Polypharmacy and Swimming hydrotherapy with excellent recovery process. I'm glad you clearly stated cage/crate rest should be well defined to Pet owners. With this i'm more confident to help Pets with IVDD and i hope to learn more from great tutors Like you in future. Thanks Once again Prof.
@oatima Ай бұрын
Thank you for the great explanation
@oosajee Ай бұрын
Thank you for the informative video! My doxie was recently diagnosed with lvl 2 IVDD. Took MRIs and decided to go the conservative route since her pain was manageable with medication and the hernia was relatively small. I’m already seeing a huge improvement in her walking after 5 days. Will be starting physiotherapy and hydrotherapy tomorrow 😊 Biggest difficulty this far has been keeping her resting, as she’s full of energy now that we’ve found effective pain management!
@oosajee Ай бұрын
She’s on robenacoxib and gabapentin. This combo seems to work really well and I haven’t observed any side effects beyond a bit of loopiness the first day on gabapentin.
@clare-neurovet Ай бұрын
@@oosajee really glad to hear that your doxie is responding well - fingers crossed it continues
@SilvineOh Ай бұрын
I used to be scared of neurology because I found my teacher in uni to be very confusing, but watching your videos and also your presentations at the ISFM Congress have made me feel more confident! Thank you very much!
@clare-neurovet Ай бұрын
thank you - this means so much to me - to know that these videos make a difference and fulfil their purpose which is a free learning resource for veterinary professionals providing practical neurological knowledge.
@cassiasantos2809 Ай бұрын
Very good. Thanks 🎉
@clare-neurovet Ай бұрын
thank you for taking the time to comment ! It is appreciated
@cassiasantos2809 Ай бұрын
Thanks for sharing this case .
@garybonacci2031 2 ай бұрын
Good video!
@oatima 2 ай бұрын
What is the suitable time to perform an MRI scan in an epileptic dog after it has a seizure event to prevent postictal edema sign in MRI?
@clare-neurovet 2 ай бұрын
kzbin.info/www/bejne/a5SqgYJ5g8yIp9E Discussed at timepoint 12:00 !
@oatima Ай бұрын
@@clare-neurovetTHX
@AnnieRuler216 2 ай бұрын
I have had all over pain for years. I now am looking for chores to do because movement is not painful and I am not drugged up! Almost 20 years of playing solitaire, my life has changed!
@clare-neurovet 2 ай бұрын
really interesting to hear this and so glad that you have pain-free life back again after 2 long decades
@JusttRaquel 2 ай бұрын
I just found this channel. Thank you so much for your content! I have an 8-year-old 4 lb Yorkie with chiari like malformation and syringomyelia. I've always wondered if it's okay for him to fly in an airplane with me??. He was diagnosed at 3 years old. And has been on omeprazole and gabapentin regularly
@clare-neurovet 2 ай бұрын
the general advice is that it is okay for animals and people with Chiari malformation to fly.
@joannaszymanska8336 2 ай бұрын
Thank you so much for this! I am revising for my exams and this is great. Thank you for including so many cat videos (vet med is rather dog-dominated!).
@kateintheartery8281 2 ай бұрын
Thanks for this. 8 years ago I had a cavalier with chiari malformation and SM, and gabapentin seemed to keep her mostly comfortable for a few years and then she got more painful episodes so I changed to pregabalin. The painful episodes seemed less frequent but were still intense. They occurred out of the blue but were worse with excitement or if she was in the hot sun. One bad one occurred after someone left salty crisps lying about which she ate. I am convinced this induced a very painful episode for her. At these times she would scratch intensely at the back of her head and then collapse on the floor scratching and then he body seemed to go into a spasm as if in pain, but she was still aware and awake. They tended to last a minute or so and then she got up as if she was tired. I tried many other drugs for her as well over the years but the pregabalin seemed most effective.
@clare-neurovet 2 ай бұрын
thank you for your observations! - it is possible the crisps triggered something because humans with this condition can described abnormal sensation in tongue or when swallowing
@JayMikaelson 2 ай бұрын
Thank you for this video, Professor.
@clare-neurovet 2 ай бұрын
so glad you found it useful!
@joannaszymanska8336 2 ай бұрын
Thank you so much for your video. This is invaluable help!!!
@clare-neurovet 2 ай бұрын
so glad you found it useful
@cavalierjourneyoflove 2 ай бұрын
Hello, i just found yourbpage today, April 29, 2024. Is there anyway you could contact me?? I am in dire straights. I need advice and help. I took my Cavalier to a Neurologist and she put him on Prednisone along with other drugs. He has been on them for a while now at least 2 yrs. He just turned 6yrs and i am so upset because I dont want him on this Steriod anymore, and I am being told that is all that will help him. PLEASE HELP ME... Thank you
@gigglingchicken8444 2 ай бұрын
My dog was just prescribed pregablin for seizures or possible dyskinesia. He was on generic keppra, but his anxiety has greatly increased since he started that drug. Do you think I should be concerned in using pregablin as an alternative treatment for his seizures?
@clare-neurovet 2 ай бұрын
Really a conversation to be had with your vet - I am afraid that I cannot comment on the management of individual animals although I am always happy to contact me via usual channels to ask advice on challenging cases.
@hikikomori104 2 ай бұрын
Thank you for the lecture! It was so helpful !
@clare-neurovet 2 ай бұрын
thank you for you kind comments - so glad that it was useful
@luhltv9935 3 ай бұрын
Thank you ❤❤
@zm6186 3 ай бұрын
Great video! Thank you Prof!... Sorry, but I thought the whippet/Italian grey hound has a hypermetric left fore?
@clare-neurovet 3 ай бұрын
Yes you are right - I apologise - I got the sides mixed up (DUH!) - well spotted. the correct text is hypermetric gait on the left side (especially left fore and localised as paradoxical (right) vestibular syndrome involving left cerebellum
@zm6186 3 ай бұрын
@@clare-neurovet Got it! Thank you. Thank you for this channel. A real gift!
@clare-neurovet 3 ай бұрын
@@zm6186 so glad you like it
@JayMikaelson 3 ай бұрын
Dear Professor Rusbridge, thank you so much for this video, it was very informative. I have two questions, please (unrelated to Pregabalin, though). What is your opinion on frunevetmab and bedinvetmab, please? I have been working with pets, and unfortunately it has been observed that many (some overall healthy, others with osteoarthritis) pets’ health deteriorated either shortly after the injection, or after few months of treatment. Some go blind, others get paralyzed or develop tonic/clonic seizures, ulcers, kidney issues, to name a few; or die. It has also been noticed that many vets in UK are prescribing those drugs either without a proper OA diagnosis, basing on presumptions/as a “just in case” solution; or for other health issues (for example, constipation, kidney issues…, toothache etc.). I believe many people, myself included, would greatly appreciate if you could please share your opinion on those medications. Second question relates to pet strokes and idiopathic epilepsy. Feline patient, age 13, healthy, suddenly developed occasional tonic seizures (only), diagnosed with idiopathic epilepsy and treated with Levetiracetam. Due to misdiagnosed stroke mistaken for an epileptic attack few months later, patient was prescribed Phenobarbital on top of Levetiracetam. Developed excessive scratching of ears and face, which continues months after, despite stopping Phenobarbital after 10 days. No underlying cause can be found (vet & neurologist). Would that be a likely result of the stroke? I would appreciate if you could please discuss feline stroke in one of the videos as well. Thank you in advance. Respectfully, J. Mikaelson, LLB, Pet Rescuer LFPCSA (Lost & Found Pets in Cambridge and Surrounding Areas)
@clare-neurovet 3 ай бұрын
Thank you for your kind comments I have not see the problems that you describe with the nerve root growth factor inhibitors however I would say that many older dogs/cats that are "slowing up" may be initially assumed that their signs are due to osteoarthritis and given those drugs - when in fact something else is going on. Drug reactions are not typically months after giving a drug they are usually within days. It would be unusual for a stroke to cause a pain syndrome unless in the thalamus and in that instance the scratching would be one side only. So to which region of the brain was the stroke? Strokes are rare in cats in the UK - there typically has to be a predisposing cause of embolism (something blocking a block vessel) and most reported cases have involved the cerebellum . I don't think I have ever seen a stoke be a cause of acquired epilepsy in a cat. Idiopathic epilepsy is when the structure of the brain was normal. If I was to give a lecture on strokes in the cat then it would be quite short and mostly the cases in this paper and a couple more pubmed.ncbi.nlm.nih.gov/17317258/ . Some people confuse "strokes" with vestibular disease (balance problem) - some vets say "stroke" rather than vestibular disease because they think it is easier for caregivers to understand but generally that just causes confusion!
@JayMikaelson 3 ай бұрын
@@clare-neurovet thank you so much for reply and information. They couldn’t find anything as underlying cause of the stroke, his MRI was clear. It happened right after he stopped eating, his bowl was directly on the floor; he started walking really slowly and in circles, crossing his front paws like he didn’t know how to walk, was very confused, dilated pupils. After few seconds he sat down. I took him to the vet straight away, and by the time we got there he was fine. Prescribed phenobarb on top of levetiracetam, and after few days the scratching (both sides) has started. I then insisted on referring him back to Queens Vet Hospital to see neurologist. They did all the tests and everything was ok, but saw the video of his stroke and disagreed with his vet’s epileptic attack diagnosis. Stopped phenobarb, left levetiracetam only, as it was too much for him with both meds. The scratching continues, although it’s a bit better with steroids. Since that event, I have raised his bowls 8 cm, and it never happened again. As for his epilepsy, it started last July, completely out of the blue. He started shivering for about 2 days, then started having paw, ear or whiskers twitches; these are his only symptoms. First, we suspected FARS, but again-neurologist wasn’t sure, his tests were normal (there were some changes in the brain, but minor and apparently normal at his age), so his diagnosis is FARS or idiopathic epilepsy. His twitches happen only when he lies down, either asleep or awake. No FARS triggering sounds are present.
@clare-neurovet 3 ай бұрын
The book that I mention in this video is "The IVDD Handbook: Helping your dog through back and neck problems" Paperback ASIN : B0BFTWP9H5 ISBN-13 : 979-8351305097 it is really helpful in explaining how you build-up physiotherapy and also appropriate crates sizes etc (NB book is nothing to do with me and I don't gain anything from promoting it- I just think it is a great resource for vets, nurses and care-givers)
@zm6186 3 ай бұрын
Thank you Professor, great informative video. I wonder if i could clarify regarding physiotherapy for those not going for surgery.. when will we institute it? After 4 wks of so of cage rest or whenever signs have improved and stable? Thank you.
@clare-neurovet 3 ай бұрын
you should start physio immediately but only simple exercises - I recommend this book "The IVDD Handbook: Helping your dog through back and neck problems" Paperback ASIN : B0BFTWP9H5 ISBN-13 : 979-8351305097 it is really helpful in explaining how you build-up and also appropriate crates etc (NB book is nothing to do with me and I don't gain anything from promoting it- I just think it is a great resource for vets, nurses and care-givers)
@zm6186 3 ай бұрын
@clare-neurovet OH I see. Thank you. !
@DrDianeDAddie 3 ай бұрын
This is a brilliant film! Thank you for such a clear explanation.
@clare-neurovet 3 ай бұрын
thank you so much for your kind comments
@nenadmladenovic2094 3 ай бұрын
Simply the best
@kateintheartery8281 3 ай бұрын
Thanks
@user-xj9vj7by5n 3 ай бұрын
Thank you very much for the lectures and books about Syringomyelia! Prof. Rusbridge, could you please tell me, is it possible to get your online consultation? Is there an online appointment? We live in another country, my Cavalier King Charles Spaniel has Chiari and Syringomyelia (According to MRI, extension of the central channel in the area C1-Th1, up to a maximum of 7.7x6.5 mm). The dog is 11 months old; a veterinary neurologist recommends not to take gabapentin, but to do surgery (foramen magnum decompression). We have some doubts. There is an MRI disk and a video of symptoms (phantom scratching), if a consultation is possible, please let me know. Thanks a lot!
@clare-neurovet 3 ай бұрын
Online consultations are available through Wear Referrals and the cost is the same as the face to face consults www.wear-referrals.co.uk/
@ranbirchudasama3323 3 ай бұрын
What is the success rate of cagerest?
@clare-neurovet 3 ай бұрын
generally quoted to be at least 80% successful but depends on the severity grade with less for grade 5 dogs and also depends on breed eg French Bulldogs do more poorly because of there other problems related to being flat faced (when anxious / painful their breathing difficulties can be life threatening or even fatal).
@xAllyCat11 3 ай бұрын
My girl was diagnosed with Chiara but not SM at least yet. She also has allergies so it's been hard to figure out what's what. The Neuro implied she shouldn't have pain if she doesn't have SM but I strongly suspect at least some of her issues are Neuro pain.
@clare-neurovet 3 ай бұрын
Yes there can be pain associated with Chiari malformation alone. There are quite a few published reports and this is one www.ncbi.nlm.nih.gov/pmc/articles/PMC6766577/
@BeWild358 3 ай бұрын
As a biologist and dog owner I appreciate your science based content. Hope you keep going and get plenty of subscriptions!
@clare-neurovet 3 ай бұрын
thank you so much for your kind comments !! I enjoy making the models - I have a antique kit that was passed to me by my biochemist father
@CikisHelyzet 4 ай бұрын
Amazing content. Thank you so much.
@clare-neurovet 3 ай бұрын
thank you so much for you kind comments
@user-je4xe2hy2y 4 ай бұрын
Cracking video, will be forwarding this to my collegues - thank you!
@clare-neurovet 3 ай бұрын
thank you - so glad you found it useful
@heatherjaggers5884 4 ай бұрын
This is very helpful for how to use wedges.
@clare-neurovet 3 ай бұрын
thank you Heather - glad you found it useful
@TheAlyssa2469 4 ай бұрын
Thank you for your presentation ! Sums it up in such a clear manner ! Helped me revise a few notions during my internship's neurology rotation !
@clare-neurovet 3 ай бұрын
so glad that you found it useful
@twotwinningcavs 5 ай бұрын
Love these videos. Is there any research to suggest vitamin and mineral supplementation alongside prescription drugs to be helpful in reducing pain?
@clare-neurovet 2 ай бұрын
No strong evidence for mineral and vitamin supplement - this was recently reviewed in human medicine (neuropathic pain) here DOI: 10.1111/papr.13291 and the conclusion was " Based on the review, we cannot recommend any supplement (for chemotherapy induced peripheral neuropathy)....although further research into N-acetyl-cysteine, l-carnosine, crocin, and magnesium is warranted....... Studies with goshajinkigan, vitamin B12, vitamin E, and glutamine had conflicting results regarding efficacy, with one goshajinkigan study finding it harmful. Guilongtonluofang, ninjin'yoeito, and antioxidants showed various degrees of potential effectiveness. Regarding diabetic peripheral neuropathy our review supports the use of alpha-lipoic acid, acetyl-l-carnitine, and vitamin D.... Check out my video on PEA which is the supplement most commonly given to dogs with neuropathic pain.kzbin.info/www/bejne/g4K0e62eiZ2srrssi=gUvfOJrDq32wj6QL
@twotwinningcavs 5 ай бұрын
Are there any benefit in feeding foods that are seen to lower CSF naturally?
@clare-neurovet 4 ай бұрын
Possibly! - But you will have to educate me because I am not aware of foods that reduce CSF production in animals. In humans there is a link between (not so) benign intracranial hypertension and metabolic disorders / obesity. Healthy eating and weight loss can benefit (but that may be a chicken and egg situation i.e. there may be a metabolic disease causing the weight gain and the ICH). In animals I advise avoiding obesity and one of the reasons why I encourage exercise (if possible). This is a link between too much and too little vitamin A and CSF but that is not a normal healthy diet. Having natural diuretics, eg caffeine isn't recommended for animals.
@twotwinningcavs 5 ай бұрын
Is phantom scratching alone seen as a type of pain?
@clare-neurovet 4 ай бұрын
Dogs with phantom scratching are also in pain as well but no.. phantom scratching is a maladaptive scratch reflex similar to fictive scratch
@michaobrebski507 5 ай бұрын
Hi profesor, my dog is 10 y o and has back pains. Two years ago our doctor ordered gabapentin 100 mg twice a day. Now it does not work as good as before and higher doses of gabapentin provoke side effects. Now the prescription is to switch to pregabelin 50mg twice a day. Can we switch immedately to this dose or it requires some transitional time in giving 50mg once a day or maybe giving half of daily doses of gabapentin (morning) and pregabelin (evening) on the same day. 🙂
@clare-neurovet 4 ай бұрын
I suggest looking at the pregabalin video (I do discuss that) but a straight switch is best / easiest.
@nenadmladenovic2094 5 ай бұрын
Wow, this is more than just veterinary medicine! It's like magic, truly helpful for all vets and students. Thank you so much!
@clare-neurovet 5 ай бұрын
thank you so much for your positive comments