Why MDMA did NOT get FDA approval
15:09
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@Thaumius
@Thaumius 38 минут бұрын
In the michael addition of the vinyl group (20:12), what explains that it occured from the top face?
@user-mp4bc9qp2x
@user-mp4bc9qp2x 2 сағат бұрын
great video really interesting. it's great you split up the topics. as a practicing organic chemists i personally prefer the second half but you do a good job of making even me interested from the beginning, even though it's more biology than i can normally stomach.
@TheMcSebi
@TheMcSebi 3 сағат бұрын
well researched
@pzkmpfIV
@pzkmpfIV 3 сағат бұрын
waht
@Nvortex15
@Nvortex15 4 сағат бұрын
unsubbed for AI trash
@dvdvelde
@dvdvelde 54 минут бұрын
Where?
@bigironenthusiast9343
@bigironenthusiast9343 13 минут бұрын
whats the ai?
@mickaelfer5621
@mickaelfer5621 4 сағат бұрын
The main reason why we try the synthesis ? The fun bro 😎
@Nepetaa
@Nepetaa 4 сағат бұрын
Sollux reference?
@Farvadude
@Farvadude 4 сағат бұрын
did hussie know about this stuff before it went viral? he knows a lot of esoteric shit
@surreal.motion.original
@surreal.motion.original 5 сағат бұрын
SUBTITLES!!!!! You should do one for Curcumin that actually treats cancer. <3
@Chemicator
@Chemicator 5 сағат бұрын
The synthesis route of Kalmanol was really interesting, particularly the ring closure of the core macrocycle. Great job!
@seankinney3797
@seankinney3797 6 сағат бұрын
At 18:39, why does the Gringard reagent not react with its own ketone group? I don't see why that ketone group would be any less reactive than the ketone of the other fragment, but I am only an undergrad.
@KrasaGalyaShararam
@KrasaGalyaShararam 4 сағат бұрын
Coordination with LiCl prevents Grignard reagent from reaction with its own carbonyl group. You should definitely check out 'turbo Grignard reagents' to learn more about it
@mickaelfer5621
@mickaelfer5621 4 сағат бұрын
That s indeed a nice question :)
@mimortal1000
@mimortal1000 6 сағат бұрын
Loved your exercises, I would love to do more of them !
@exoric7408
@exoric7408 6 сағат бұрын
Great content and in-depth explanations as always !
@Trizzer89
@Trizzer89 8 сағат бұрын
If it cures epileptics, why not use it in medicine?
@totalsynthesis
@totalsynthesis 7 сағат бұрын
Their claims were cap, it doesnt
@MandrakeFernflower
@MandrakeFernflower 6 сағат бұрын
It really doesn't it just gets you fucking munted It does seem to have antibacterial and painkiller effects however - there is an unusual drug called "Labrador tea"
@dannyagunbia206
@dannyagunbia206 9 сағат бұрын
One of my favorite accounts
@totalsynthesis
@totalsynthesis 8 сағат бұрын
🙏🏻
@KwK-c7t
@KwK-c7t 9 сағат бұрын
This content is amazing, i love to dive deep. Of course i learn something and i like it a lot. Thanks for your work 🖖
@totalsynthesis
@totalsynthesis 9 сағат бұрын
Thanks, love to hear that!
@kekaodotexe443
@kekaodotexe443 9 сағат бұрын
good videos first of all
@totalsynthesis
@totalsynthesis 9 сағат бұрын
You were fast af
@totalsynthesis
@totalsynthesis 9 сағат бұрын
Thanks for watching! Hope you learned something new or liked it!
@davidisthis
@davidisthis 2 күн бұрын
And thank you, for teaching us.
@psyche.deluxe3539
@psyche.deluxe3539 3 күн бұрын
Interview dr. Mash
@Juicyexe
@Juicyexe 8 күн бұрын
What courses/programs did you do in uni?
@totalsynthesis
@totalsynthesis 7 күн бұрын
Basically almost everything within chemistry and biology to some degree!
@limmuquan4796
@limmuquan4796 8 күн бұрын
Excellent video and fascinating discussion, I really learnt a lot. But just to nitpick a bit, at 19:59 you forgot the other -Ar substituent on the structure at the bottom left
@totalsynthesis
@totalsynthesis 8 күн бұрын
Thanks so much! And good catch, I always forget something in every video haha