Dude is a fraud

I like David but his eyebrows don’t move along with the rest of his face when he’s speaking. Wouldn’t that be a kick in the pants if he’s doing Botox.

Jesus is a fictional character. When Jesus was invented as a form of earlier religions

Thank you for this podcast, I love all the information. I'm definitely subscribing to your channel. Please keep on doing these kind of podcasts! I do have a question. Is there any treatment available right now that can truly help give up smoking? I've been trying for years and haven't been able and I'm hopeful that science will eventually help me somehow. I would love to live to a 100 or more but I know smoking is not something that is helping me towards that goal, but it's so hard to quit it! Thanks again!

This guy is just part of the supplement cartel, corners the market by banning NMN so his company can make big $$. BOYCOTT DAVID

This guy is just part of the supplement cartel, corners the market by banning NMN so his company can make big $$. BOYCOTT DAVID

This guy is just part of the supplement cartel, corners the market by banning NMN so his company can make big $$. BOYCOTT DAVID

This guy is just part of the supplement cartel, corners the market by banning NMN so his company can make big $$. BOYCOTT DAVID

This guy is just part of the supplement cartel, corners the market by banning NMN so his company can make big $$. BOYCOTT DAVID

This guy is just part of the supplement cartel, corners the market by banning NMN so his company can make big $$. BOYCOTT DAVID

💯

40:18 😂😂😂😂😂😂😂😂

Truly, literally a life changing series. Thank you so much!

Does Metformin, impair mitochondrial functions?

Is there, a way, to measure, your growth hormones?

Great information👍

Love it🔥👏

Whats the best sauce for resveratrol purchase?

So do you drink the greens drink and not count as the fasting or do you drink it in your 1 meal a day

QUESTION: PLEASE HELP ..... Not counting the obvious like exercise, diet, low stress, etc., I want to know what longevity supplement elderly folks living close to the poverty level should invest their small extra cash in. I'm taking NMN 500 mg/day for $87/month, Areds2 for early symptomless macular degeneration, & multi vitamins. Are there one or two other supplements I should be taking at age 80? I have congestive heart failure, that is so far controld with heart & bp meds and lasex. What can I add to reverse aging, that I can afford?

😅what a bunch of doodoo

I would love to know if NAD boosters would work on dogs too. They die so early.

Where in the pinot noir is resveratrol? In the seeds, juice, flesh?

He’s a fraud

Shouldn’t you change your name to Dr. Flimflam? Or Dr. Shyster?

Con man. Snake oil salesman.

I'm sorry, but he looks skinny, could use 10 lbs more. So having some muscle is not good.

Ngl this smells of BS. Resveratrol has only downsides. You published research 2 decades ago and since then everything points out the tests weren't done right and it had no affect. You're worth Hundreds of millions of dollars. Why haven't you backed up your research? Why are you using sponsors?

Also, if you want to live longer, become a biological female. 😊

I don't understand the waitlist comment. Why would there be a waitlist if you can sell them to people? Why advertise if you have 150,000 people that are about to buy it?

resveratrol scammer enjoy your 720MIL

The comprehensive summary of The Science of Looking Younger, Longer | Lifespan with Dr. David Sinclair #6 reveals a profound exploration into the realms of aging, specifically targeting external aging and the interventions to mitigate or reverse it. Dr. David Sinclair, alongside co-host Matthew LaPlante, delves into a variety of treatments, dietary supplements, and lifestyle modifications designed to preserve or rejuvenate one’s external youthfulness. Here is a consolidated list of the substances and interventions recommended throughout the video, alongside the educational insights provided: Retinoids: Highlighted for their ability to reduce wrinkles and lines, yet with caution advised regarding their potential long-term effects on skin aging due to their impact on chaperone-mediated autophagy, which might be compromised with regular use. • Resveratrol: Noted for its longevity benefits, resveratrol’s effectiveness is attributed not to its antioxidant capabilities but to its role in activating the body’s defenses, enhancing sirtuin activity, and improving overall skin health. • NAD-Boosting Molecules: The discussion includes the potential benefits of boosting NAD levels in the skin using compounds like nicotinamide or nicotinic acid, which could promote skin health through sirtuin activation. • Hyaluronic Acid (HA): HA is lauded for its importance in maintaining skin plumpness and flexibility. Its abundance in long-lived organisms hints at its role in anti-aging, with the potential to prevent cancer. • Minoxidil: Known for its effectiveness in slowing hair loss and promoting regrowth, particularly in combination with retinoids. • Finasteride (Propecia): A once-a-day pill that inhibits the conversion of testosterone to dihydrotestosterone (DHT), offering a preventive measure against hair loss with attention drawn to potential side effects. • Low-Level Laser Therapy (LLLT): FDA-approved for hair regrowth, LLLT is recognized for its capacity to rejuvenate hair by possibly enhancing mitochondrial function. • Platelet-Rich Plasma (PRP) Injections: Utilized for various conditions, including hair loss, PRP injections are considered for their rejuvenating effects on hair follicles, though the precise beneficial components remain unidentified. • Cyclosporine A, Tacrolimus, and Other Compound Combinations: Discussed in the context of hair repigmentation and potential anti-aging effects, these compounds represent the frontier of research into reversing the biological mechanisms of aging. Throughout the video, Sinclair and LaPlante emphasize the intricate link between external and internal aging, suggesting that interventions targeting outward signs of aging could also have profound implications for overall longevity. The discussions extend beyond cosmetic benefits, proposing a holistic approach to aging that incorporates scientific advances with traditional health and wellness practices.

Eating collagen doesn’t do shit.

*Lucky The Disgruntled Bird . . . has Arrived from the Outer-Regions* . _Exceptional Discussion_ . Some of the New Multi-Vitamins . . . seem to Contain Riboflavin and Niacin . Collagen and Glutathione Sort-Of Help with Aging . HGH Support Suppliments with the Ls appear Good . . . although, Body Mass can Over-Increase . . . and, the Youthful Appearance Quickly Diminishes after Stopping for 3 Days . Noticed that Synthetic Hormone is Horrible for Aging . Herbs like Horney Goat Weed for Men and Fenugreek for Women seem to Increaee Hormones while Not Effecting Aging . -- -- -- 1 Thing is for Sure . . . Many Suppliments in Conjunction . . . Do Help with Aging . . . and, the Results also Appear to be Internal and Lasting . -- -- -- *BioPerine* _(Black Pepper Extract)_ . . . Really Really Increases Absorption of Suppliments . The Body Gets Warm for about 30 Minutes . -- -- -- Besides ProHealth Longevity . . . Nutraceuticals' Suppliment Stacks are becoming Quite Popular . Suppliments Stacks are Definitely the Future of the Market . Lucky Suggests that Each Stack . . . has an Optional BioPerine Included Version . -- -- -- Sorry . . . The Bird Knows that Production and Operation Costs for Suppliments are High . . . and, Intelligence People Definitely should be Monetarily Rewarded . Stacks versus Single Suppliments might be Less Profitable . . . or, Be More Competitive and Complicated . A Solution is to Create Different Stacks for 3 or 4 Times per Day . . . with and without Food . In Addition . . . Stacks that Can Taken Together . So . . . There's a Base Combination-Pill . . . and, 3 Optional Additional which are Advertised as Adding Value to the Base . -- --

2024, im watching this. Amazing work 💯👍🏼

Hi David - I understand Metformin is a chemical derivative of Goat's Rue (Galega officinalis), which you can buy as a herbal supplement. Would this be as effective as Metformin?

No

In my book, FRAGMENT, I discuss my original theory that lifespan is twice the age of sexual maturity in organisms that have any routine opportunity to breed with offspring. That's why Ostriches that mate for life can live 70+ years while turkeys that live in proximity to their own offspring, don't mate for life, and reach sexual maturity at 1 year die at 2 years. It's also why mussels that breed in unison releasing millions of sex cells into the sea have virtually no chance of breeding with offspring and live 70+ years but barnacles that mate only with barnacles in their immediate proximity and reach sexual maturity at 1 year have lifespans of two years. The principle holds true with all species of plants and animals. Oxford scientists studying senescence are studying the theory. I describe it more in my book.

Interviewer highly annoying. Talking all the time. Dommage...

very good

Does resveratrol slow down an aging prostate gland?

Cool information about life. A lot positive energy. Soo helpful 🫶

Loved this KZbin video.Thank you so much. As a health professional and personal trainer I would love to partner with Levels. Dr Sinclair, may I ask how to do get this done. I have been personally monitoring my blood glucose levels from time to time, just out of curiosity. My husband is type 1 diabetic and I have been borrowing his glucose monitor to test mine ever time I do my fasting. Its brilliant to see what food triggers higher blood glucose levels. Super interested in this field. Thank you.

David Sinclair is a snake oil salesman. Completely fraudulent and motivated by profit. Do not take his advice. Go elsewhere.

Do you feel shame for promoting a useless product like AG? You should

Why do you lie to people?

I have glaucona and am volunteering for clinical trials.

May I ask how best to correct/reverse osteoporosis which beseech most elderly. Thanks

But does not work for people with hypermobile Ehlers-Danlos syndrome or EDS because of dysfunctional collagen internally

collagen? carnivore diet and bone broth and solve the problem without stuffing yourself with supplements