013 A Review of the Action Potential

www.interactive... - Depolarization, repolarization, hyperpolarization - It's all here. Watch this for a review of the action potential.
www.interactive...

[@drhana6433]

The best and simplest video made on A.P

[@InteractiveBiology]

Glad to hear it :)

[@appiiieee]

KZbin is a teacher because there are people like you who explain concepts so well! Thank you.

[@Mr-Psychologist]

Agreed

[@preacherman9]

I have an exam next Monday and I was recommended to do this. Reading this in a text book was blowing my mind and freaking me out. But watching your 6 videos which took 20 mins and i got it. that is a testament to how good you explain this. Thanks a lot buddy. My biopsychology exam does not seem so bad.

[@jl4260]

YOU ARE A LEGEND. I have an exam on this coming up and you have clarified everything I was confused about. You rock!

[@Mr-Psychologist]

Really appreciated

[@InteractiveBiology]

@richardus Hi! Thank you for watching the video. Unfortunately, Leslie won't be able to answer specific questions as he is busy at the moment with a lot of work. But, he'll also be working on additional Biology videos, so please stay tuned for more!

[@PerfectNicolelyn]

You explained this in such simple terms, I can't believe I sat in lecture for over 3 weeks and could not get this. Now in just over 5 minutes I understood the whole thing.

[@TheLuvneet]

Honestly this is the simplest and best descriptive guidelines on this topic I have come across, thank you so much for making this! You have no idea how much easier you've made my life.

[@masakohasegawa4396]

He is an extraordinarily amazing teacher! He has the best teaching skills of anything in science. Thank you so much for sharing your brain with us!

[@meghna9479]

sure I'd be glad to share my brain sometime with you too :) come let's share brains call everybody your neighbors also

[@MinnieMouse4792]

FINALLY, an explanation I can comprehend with no issues!

[@NicoleBourgeois]

Agreed!

[@InteractiveBiology]

Glad to help :)

[@daisyinthebluebox]

Wow, thank you! I love how straightforward this was -- less confusion, more comprehension. You've saved me from the wrong answer on the exam :)

[@InteractiveBiology]

@xlPRoS All questions are answered in the Interactive Biology community forums from now on. Go to the website in the description and then visit the community.

[@InteractiveBiology]

@09BANGBANG All questions are answered in the Interactive Biology community forums from now on. Go to the website in the description and then visit the community. This is to make it as efficient as possible as we have multiple people over there to help answer questions. All the best

[@20sefora]

i have been trying to understand this for days and i just could not seem to tie it all together, until now. you are the reason that good teachers are a necessity to all human life thank you

[@thoyo]

you explain in 5 minutes what many other videos take 20 minutes to do. great time saver

[@jnmilner92]

I can't believe this 5 minute video helped me understand the material better than my instructor has, THANK YOU!

[@InteractiveBiology]

You're welcome :)

[@InteractiveBiology]

@CarpeLudus It's around -55mV, but that's not an exact number. It does vary somewhat. In terms of the Scwann cell, I'm not referring to that, just the part of the axon. I do mention potassium and the Sodium-potassium pump, but go into those topics more in other videos.

[@lydiasigurdson1259]

FINALLY able to understand this!! Great job and much appreciated.

[@nardiomer]

So simple, straight forward, and UNDERSTANDABLE!! Please be my prof!!

[@InteractiveBiology]

@cynl75 All questions are answered in the Interactive Biology community forums from now on. Go to the website in the description and then visit the community. This is to make it as efficient as possible as we have multiple people over there to help answer questions. All the best

[@stephaniebeaton1513]

Thank you so much for posting this. I feel like my teacher was talking in circles that did not make sense and your video helped set me on the right path to understanding. THANK YOU!!!

[@jonahbreg]

I thank heavens for teachers like you who really help us students comprehend better.

[@InteractiveBiology]

@mudasir99 When someone touches you, that stimulates touch receptors, and they send signals via many neurons to the brain. The touch is mechanical stimulation, which causes channels to open resulting in a receptor potential (similar to an action potential, but in neurons). The action potential is the signal that is generated in the individual neuron and that travels along the neuron. In some of my other vids, I explain that process.

[@InteractiveBiology]

@hupper12345 The membrane potential is the voltage difference between the outside of the cell and the inside. For example, if outside is 0mV and inside is -70, the Membrane potential (potential difference) is -70 - 0 = -70mV. The outside of the cell is typically considered to be at ground potential (0mV). Hope that helps!

[@whittomlin]

I'm in medical school and needed a brief and accurate physiology review. These videos were perfect.

[@InteractiveBiology]

@hawaiianGurl27 Thank you and you're welcome! :) Please stay tuned. We have more Biology videos coming very soon!

[@InteractiveBiology]

@yanirmt22 You are very much welcome. Check out the many other videos on my channel too. Lots more of this kind of content. All the best on your boards :D

[@InteractiveBiology]

@MrGuok Yes, it is always active. However, when the action potential is happening, the amount of sodium rushing in is so much that the pump is pretty much insignificant. The refractory periods are covered in detail in Episode 012. Check it out and you'll get all the details.

[@InteractiveBiology]

@kasenpoz You are welcome. If you want to understand how depolarization starts, check out episode 9. I'll send you a message with the direct link.

[@caroljackson767]

Thank you Mr Samuel for making a concept so complex, so simple!

[@InteractiveBiology]

@bellastrippin Great to see you enjoying biology so much. Keep tuning in for more :D

[@Ryosuke.Takahashi.]

Thank you very much for your demonstrations. I am studying psychology and had a very hard time grasping the pathway of a neuron concept, but you simplified that even a fool can understand. I get it and I can now define, draw and name the parts of a neuron, describe the types of neuron and its complete action potential. Keep up the great work! I'm excited to see how you break down my next study topic which is the brain. Thanks a million, truly grateful.

[@InteractiveBiology]

Karen, I'm so happy to hear that. We really aim to make this stuff understandable, so I'm glad it's working for you. Stay tuned. We have a lot more coming 😉

[@Mister_Soyuz_on_YT]

I like how the textbook shows a simple graph of Neuron voltage during its Resting State, when it's Depolarized, Peak Voltage, and Repolarized. but this here video tops what I saw on the textbook. It made studying less consuming

[@dr.johnchinonsoegu4921]

After watching this video, i had goosebumps, i wanted to cry...............Boy oh boy this is so amazing. I am going to read this topic with much ease now that i got a very clear picture.

[@sarahmairejackson]

you make it so simple. I have a test on tuesday. Thanks yo

[@mikaerek1044]

I'm in the same boat as you haha :)

[@escarface]

Your seriously making my reading and lectures more understandable wow!

[@BedrichFridrich]

Helps me a lot, english is not even my mother language but now i get it.

[@InteractiveBiology]

@EvelynNLB Thank you! Leslie has more Biology videos in the website that you might find useful. Please stay tuned for more!

[@laurelthompson6727]

Thank you sir...I greatly appreciated your kind interest and effort...in just a little over 5 mins, I am able to understand a presentation I am learning for weeks and could not grasp...thumbs up

[@ashleyritchie7286]

Thank you for making these videos!! This truly broke the process down and was very easy to comprehend and take notes for my Final!

[@juancarlosh.1418]

Thank yo so much. You explained it everything clearly and with no rush, unlike the professor I have that rushes through everything and expects us to understand. Your voice sounds calm and its easy to understand.

[@InteractiveBiology]

@diamond61789 You are very much welcome. Stay tuned for many more!

[@Lightbluefire]

the way I understand it, before hyperpolarization, the voltage is - outside of the axon and + inside, and K+ keeps flowing out, but at a point before it reaches equilibirium, the 3 Na+ for every 2 K+ pump kicks in, meaning that there will be more of a negative gradient inside the cell than outside, where more Na+'s are.

[@InteractiveBiology]

@Amethystiii Wow! You're very welcome. Leslie is great at explaining these complicated things making them seem so simpler. You can go to our site for more of these Biology videos. I'm sure you'll learn a lot more! :)

[@haneenabusada8704]

Thank you so much! You summarized the terms faster and in terms where i could understand. I watched countless videos and you were able to clear things up under 6 minutes.. Again, thank you for posting this! :)

[@aidan_quinn]

At time 3:34 there is a small error. Potassium ions don't leave because of the electrostatic force, they leave because of the chemiosmotic gradient. [K+] is much higher inside the cell compared to outside, so when the VGK channels open, the K+ goes down it's concentration gradient. The depolarization of the membrane does open the K+ channels (as you say) so K+ efflux is indirectly related to the membrane potential.

[@alwaysontherise1]

+Aidan Quinn But couldn't we argue that K would leak out of the cell even before the stimulus? (K determines the resting membrane potential because of it's leaky channels.) In other words, since it is higher intracellularly, it would go down it's gradient and pass out of the cell. Because this does not happen at a significant level, I do believe the electrical aspect outweighs the concentration.... is this what you said in your last sentence?

[@alphaWAYNE]

The best channel so far explaining about biology... and making it more fun! a million thankx to the great teacher Lislie Samuel. Thank you, thank you, thank you.

[@InteractiveBiology]

@ebanupriyah Indeed! You might want to check Leslie's other Biology videos. Like this one, they will make Biology easier for you to understand. Stay tuned for more. Have fun!

[@diamond61789]

Fantastic video! Touches on everything I needed to know about APs for my college physiology course, great pace and very easy to understand. Thank you so much

[@InteractiveBiology]

@helenamazzahutt Glad you found value in our Biology videos! Please stay tuned for more uploads coming very soon!

[@emikoisabel]

You are amazing! Here I was crying about being terrified about my upcoming biology exam and I find your glorious videos. Thank you so much!

[@InteractiveBiology]

@CarpeLudus Yes, the positive does repel it. It's a positively charged ion. + always repel positive. That, plus the fact that the Equilibrium potential is around -93 will cause it to leave the cell. And there's no such thing as a leaky potassium v-gated channel. There are leaky channels and V-gated channels that serve different purposes. But there are other videos on my channel that go into those specifically.

[@brownboys16]

@InteractiveBiology I LOVED UR VIDEO it was really helpfull with my midterm question 3) Describe how an action potential begins and what happens within the neuron during its transmission. thank you.

[@letaj4751]

thank you this was a very clear example for me... Studying for Advanced Human Physiology exam.

[@InteractiveBiology]

@tbolch So glad to hear. All the best on your exam. Let me know how it goes.

[@sarahstevens6897]

Thank you so much! you make it easy and clear to understand and actually finding it quite interesting now :)

[@jamesmccafferty8869]

So much easier to understand than how it was being explained in class!

[@wphiland]

Plain and simple - you make it really easy to understand. Thanks!

[@srfangl01]

My neuroscience teacher can definitely take a queue from your lecture! geeesh. Makes so much sense now! Clinical pearls!

[@Amitsuman101]

Great explanation sir! It was really really simple version I've came across. Some values told and written over here are different then the book Guyton's, but that's ok.. doesn't make much difference in explanation. I'm so happy I watched ur video. Thank you sir..!

[@KC-hp2mg]

I just shared your channel with my online A&P class thank you so much!

[@narendeepan]

Hey I studied my book for about 4 hours to understand this. But this video made me understand the whole process within 5 minutes. This is very clear and will help me in my upcoming exam. I really appreciate your efforts.

[@saran6175]

Thank you so uch for your video. You have explained somthing that has taken almost 1month for me to understand from anyone just simple and easy explanation. God bless you

[@nikkiclark8697]

Thankyou you've made this really simple and it's so much more concise you can't get lost in all those processes, thank you!!!! Short sharp explanations are better than long winded ones.

[@InteractiveBiology]

@lostinwonderland89 So glad to know that you are finding value in the videos. stay tuned for much more.

[@AuggieX1]

Very simply explained. Thank you for helping with my confusion. Who doesn't like this???

[@nisaaroberts]

Oh, THANK YOU. I agree with Jun, this is the best and simplest video I have come across.

[@carolinetaylor528]

after two years i think I finally understand action potential. thank you :)

[@cheryl2915]

I've watched so many video's, but these make the most sense to me, thank you!!

[@patty9285]

Thank you so much! You are the only reason why Im not failing anatomy!

[@kantnesragnarok6128]

if you can explain chemistry concept and thermodynamic in term of sodium potassium pump than it would be amazing sir

[@josephsmiley2763]

By far one of the best videos that explain this concept!!!

[@rosesutera5994]

Perfect review of the Action Potential. It is so clear and easy to understand. Thank you.

[@harrydon5973]

God Bless You from a Jamaican Medical Student!

[@Jtrp73]

this is an amazing video. so simple. loved it. thank you very much!

[@tmcnuz]

Very Clear and Concise!! The only thing I wish you would describe is the absolute and relative refractory periods. Thanks!

[@ChilangaBanda08]

Simple, straight to the point (my brain) !!! Thank you, greetings from Houston, Texas...

[@InteractiveBiology]

@tmcnuz Thank You! Leslie has a lot of stuff to do at the moment working on other Biology videos for the website. He'll get to more topics soon so, please stay tuned!

[@jodyemanuel6371]

The is best Action potential video that I have ever seen! Thank you so much!

[@InteractiveBiology]

@zepoe Thanks for the feedback. All the best!

[@dadalacks]

good work dude. When I pass my anatomy exam I promise you I'll donate. Your efforts are really excellent.

[@InteractiveBiology]

@whittomlin Glad to know they are helping. All the best in Med school!

[@janjones25]

This has been such a great explanation. I have a test tuesday and this has help me a lot.

[@19boulder11]

I'm amazed that I actually finally comprehend this. Well done.

[@InteractiveBiology]

@haaayz That's great. All the best on your test. Let me know how it goes!

[@InteractiveBiology]

@mihae Thank you, thank you so much! Please stay tuned for more!

[@vivianyueli4155]

wonderful lecture! You make it all simple and easy! Thank you so much!

[@christindobbs2342]

Finally a good easy video to understand, thank you!

[@mikaerek1044]

Man oh man you're helping me out with my Psyc mid term :) thank you very much

[@BlikeNave]

@xlPRoS That is happening always, not just after repolarization. It is to keep the ion concentrations in line.

[@ihaveLight]

The answers is yes! As the cell potential reaches -70mV the potassium channels are closing but "slowly" by the time they close cell potential passes past the -70mV. In other words potassium channels have lag time.

[@tbolch]

Thank you for your videos. I am doing my first unit in Psychology in Australia & we briefly cover Biological Bases. I kept getting stuck on Firing of a Neuron & your videos have helped me immensely. Fingers crossed I will do well in my exam in 4 days time.

[@softlynoted]

Wow. Best explanation I've found so far.

[@333teebee]

WOW! Thank you so much for clarifying the action potential! I was so lost before watching, and now it all makes sense!

[@InteractiveBiology]

@carmeyeii Thank you very much! Stay tuned for more!

[@annakotikian8171]

Thank you very much for a very simple explanation of a quite difficult thing.

[@InteractiveBiology]

@haaayz That's so AWESOME. Glad to know the video helped and glad your test went well. WOOHOOOOOO! Congrats to you, and tell your friends I send my congrats to them too.

[@tanyabilsbury]

Thank you! That was very helpful. The information was well-organized and well-illustrated.

[@InteractiveBiology]

@sweettreat490 Glad to hear that it's helping. Stay tuned for many more!

[@horaceroyal5289]

this guy sounds trinny, this just made CAPE studies alot better thanks

[@Anonymous88660]

Thank you, Very Helpful.Love your videos. Short, simple and straight to the point.