Pharmacology - ADRENERGIC RECEPTORS & AGONISTS (MADE EASY)

[@SpeedPharmacology]

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Where can I find notes in patreon app?

[@SpeedPharmacology]

@@samamakhan202 You can access study notes by becoming an 'Ultimate Supporter' on Patreon :)

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[@SpeedPharmacology]

There seems to be some questions regarding alpha-1 stimulation in the kidney, and I might have made a mistake. Alpha-1 receptor stimulation in the kidney does not directly cause the inhibition of renin release. Instead, it indirectly leads to renin release. Alpha-1 receptor activation causes vasoconstriction in renal blood vessels, which reduces renal blood flow and glomerular filtration rate (GFR). The decrease in GFR triggers a compensatory response that includes an increase in renin secretion. So, alpha-1 receptor stimulation ultimately promotes, rather than inhibits, renin release in the kidney.

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How did this video sufficiently explain 90% of my 2 hour long adrenergic agents lecture in 17 minutes? TYSM saving my butt for my pharm final

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@Speedpharmacology Thanks for making such good lectures. They are really helpful. I want to make a correction. According to lippincot 6th edition B-2 receptors increase release of glucagon not the insulin

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Yes glucagon and glycogenolysis as well

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[@adityab.v.2832]

Also I've some doubt about it and with Beta 1 receptors they're vasodilators.

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Wow, the best lecture I have ever seen clarifying adrenergic receptors. Thank you.

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Thanks a lot. It's true you made this easy. Initially I was struggling with it, but now I can even sing a song about actions of receptors when stimulated and sympathomimetits. Thanks

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I was confused with alpha 1 and 2 receptors. now is clear. thank you so much

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For those confused, urinary detrosor muscles relax or expand, while the urinary sphincter constrict. Resulting in urine retention and the lack of urge to urinate.

[@alinidhammohammed4259]

Thank you very much. Beautifully explained and the level of details is perfectly balanced. I’ve never been so confident in adrenergic pharmacology as I am now.

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[@SpeedPharmacology]

This is covered in the pharmacodynamics video. Check it out

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[@arishazaidi5850]

As much as i know and have researched thoroughly about,(please correct me if i am wrong)Alpha 1 adrenergic receptors are not found on kidney to reduce renin release.Beta 1 however are present on JG apparatus to increase renin release because in fight or flight situation u need RAAS to constrict ur blood vessels and aldosterone to retain water and salts in case you bleed.Alpha 1 are however found on blood vessels going to kidney to constrict them so less urine is formed in emergency situation.Overall good video.thank you so much

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