10 Closed Loop Systems explained

Hybrid closed-loop is a system which connects a continuous glucose monitor with an insulin pump to automatically adjust insulin devilry using a clever brain ( algorhym). In this video, I am breaking down all 10 commercial systems with all the information you need about them from target glucose to CGM interoperability.
Want to buy me a coffee, you can use "KZbins Thanks" next to the share button :)
My Closed Loops Diagram in 4K: ne...
1. Diabeloop www.diabeloop.com
2. Lilly Closed Loop System
3. CamAPS camdiab.com
4. ControlIQ www.tandemdiab...
5. MyLife Loop www.mylife-dia...
6. Omnipod 5 www.omnipod.com
7. Tidepool Loop www.tidepool.o...
8. Bigfoot Autonomy www.bigfootbio...
9. Beta Bionics - iLet www.betabionic...
10. Medtronic 780G www.medtronic-...
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[@TypeOneTalks]

Wow! Awesome video on a very important topic. I can't wait to be looping with control IQ really soon! Thank you Kamil for doing this!

[@haydengrayfilms]

I’m so excited for the future of diabetes management. I know eventually we will have a completely set and forget pump that will manage our sugars for us.

[@cambuss8272]

Thanks Cam from another Cam from across the pond in Canada. I just subscribed to your channel tonight and have watched about 5 or 6 of your videos already. Yesterday I bought an OrangeLink from RileyLink and plan to get started with closed looping soon. I really appreciate your honesty and candour on these products and showing what all is available. Keep up the great work!

[@johnm6216]

That was a really good information source. Good to know there are so many options out there. Thanks for taking the time to put this together

[@diabeticsassemble7328]

Such a great video! Well done! That chart looks complex. I really like the tidepool system and the omnipod 5 looks good. Beta Bionics looks really interesting too! Also well done on the smooth transitions lol

[@yazonay3226]

Just got the 780G which is a closed loop system and absolutely loving it!!

[@Nerdabetic]

Thanks for sharing!

[@SwissPGO]

Hi yaz, I'm happy for you. After a few months now , the 780G just doesn't work properly for me. I had better average values when managing manually (HBa1c around 6.5). Problem is, when it is in smartguard mode, there is no way to put a real bolus to get glucose levels down more quickly. The SmartGuard is just not aggressive enough. One would have to cheat and fake taking Carbs, but that also causes problems with the Algorithm . Also no way to temporarily modify the basel rate. It definitely does not know very well how to deal with a pizza. I have a quite good idea what my carb ratio was on the previous pump. But the 780G keeps adjusting the amounts down, resulting in too high levels. I was really hopeful that the 780G would deliver, but I'm most of the time between 8.5 and 10, where as my target range is 5.5. I do sleep better though: I silence the pump, and during the night glucose levels very slowly descend to 5.5, but it takes about 6 hours to get there.

[@ukaszzwirblis8484]

Thank you Kamil

[@frankl4497]

Another great video Kamil... look forward to your presentation at Australian Diabetes Expo 2021

[@locomademoiselle]

Absolutely amazing - I'm starting to dip my toe back into the online diabetes world as I'm researching what my next pump & closed loop system might be! REALLY USEFUL VIDEO & CHART - my brain thinks in charts so this was just perfect, thank you so much!!!! Really interested in the t-slim, yspo & medtronic that are currently available (also really appreciate your comments on availability!), really excited for future of diabetes tech, it's getting there guys!!!!xx

[@Nerdabetic]

My brain totally thinks in charts too ✨😂

[@hayleybridgewood7613]

Started omnipod dash today and I 100% have to know how you’ve made that wall behind you!?? It’s amazing! What better way to reuse the pods rather than sending them to land fill. Please can you tell me how you’ve done it xx

[@heathmorley2035]

As alway great and informative

[@andricheli]

Wow. This is a great video. I am using DIY Loop and love it. Omnipod 5 looks cool but I still prefer my current DIY set up. Just hoping Dexcom continues to make the Eros pods.

[@exazapperNy2853]

Never been a fan of classical pumps, so I'm very excited about trying an OmniPod with a closed-loop system. Or another patch pump for that matter, it seems they aren't the only company in that space anymore :O Indeed, I think it would be super interesting if you could make a video comparing different pumps, specifically more compact/unintrusive/tubeless models.

[@joraston]

It would be great if you could also include Australia please

[@ebouchut]

Really helpful. Thanks Kamil for your researches. Great video.

[@oliviabasham]

All I want for Valentines is a closed loop insulin delivery system...

[@Nerdabetic]

Loop loves me, Loop loves me not. Loop loves me, Loop loves me not..........

[@TypeOneTalks]

Me too!

[@joshbuxton5397]

Thank you for all the information you provide to the community. I am currently using the DIY loop as you are in this video. I have been following the progress of the tidepool loop approval very closely. I have not been able to find any information since the time of this video. Do you have any insider information on the process? It would be a very exciting opportunity for so many. Thanks again!

[@ronnievanderlinden]

Good vid Kamil! For me I was planning to use AAPS and that has not changed. I believe the second gen closed loop commercial systems will be the one where the real usp's come up.

[@Nerdabetic]

AAPS is amazing! That’s super exciting. Enjoy.

[@sarahwolfmoon]

Awesome 😎

[@fatterthantheshad0w]

Another Great Video, it seems diy closed loops lead the way and forced commercial development to speed things up. Here in the UK commercial closed loop systems will only be widely available for self funded patients. I watched your excellent loop series. When you can, do a similar break down for the different diy systems. I believe the diy loop system people set up largely depends on what hardware they already have access to, for example I have an NHS supplied Insight pump and Libre and use an android phone hence I only needed to add a MiaoMiao to set up AAPS.

[@krystalhall1226]

I have insight and libre too and want to work out closed loop. Can you tell me what miao miao I need please

[@zarasbubble1748]

Great video!!! I’d love to hear more from you on Omnipod Horizon. Speculations welcome, such as release in the UK (if it will be before/after US, if Brexit may have any effect on UK approval as I believe before it was one approval process for the whole of EU) Also if one is about to upgrade their pump if it’s worth holding off etc..

[@silviamunoz4935]

Thank for the video. I can't wait for the omiepod .. the new pod . I'm a podder already. This is exciting news

[@Nerdabetic]

Thanks a lot!

[@millybassett7676]

This is wonderful news. I hope it will show readings on my samsung watch as well. I do not have apple. Will it be waterproof like the G6? I hope it will be 15 days so we only have to worry about changing it twice a month. I hope it is affordable to make a diabetic's life a lot easier. God knows we suffer enough.

[@minejager1818]

Can you please keep us updated about the new Dana I pump? I'm very interested in the RS but seeing that there will be a successor peeks my interest even more. However I can't seem to find anything about it other than a row of YT videos. Is there any other place to look for information?

[@frankvanolffen1901]

Why not include the dutch InredaAP in your list? It has a CE status.

[@billyg8614]

Kamil, You mentioned Beta Bionics dual hormone pump. What are your thoughts on dual hormone (insulin, glucagon) closed loop system? That is, if your CGM detects onset of hypoglycemia, the pump would micro-dose glucagon for correction.

[@Nerdabetic]

I think it’s amazing and will be life changing to many. I do not think they publicly made any comments on that. I would assume it would give tiny doses in a same way closed loop systems do with insulin. What do you think about this idea?

[@chuckschillingvideos]

I'm not the least bit excited about closed loop systems. I don't get a very good feeling that they are going to work very well for patients with profound insulin resistance (like me) and I think I will do better if I and I alone determine my basal rates and bolus quantities.

[@TheMonsieurpolo]

Thanks a lot ! Interesting video as usual. Nice World.

[@saraheart2804]

I really believe the US is behind the times with diabetic care. I think finances are a big problem.

[@gblagden0524g]

This man is fantastic. What a guy. Is there a way of having your BG beamed to a Alexa device so it’s always on and visible around the house? Also same question for in the car - how do I get my BG always visible on a device? Thank you sir.

[@Nerdabetic]

Thanks a lot! Yes to both. Yes to Alexa and Car, both with Sugarmate sugarmate.io Hope it helps

[@locomademoiselle]

Also, are there any major updates as of March 2022? Thank you!! :)

[@Nerdabetic]

No. Sadly the situation is very much the same. Eversense is in partnership with Beta Bionics. And Omnipod 5 has been approved in the US. Thanks for watching

[@lacy71x35]

Anyone know if there's anyway to READ a LIBRE 2 w/ an Android (Note 9)? This is ridiculous, I have to carry a reader for the Libre 2, a PDM for my omnipod & my phone 🤯😡

[@hereist4nd140]

Where is the inreda artificial pancreas? And do all these pumps give off glucagon aswell?

[@MrSteven3110]

Great video - you mentioned that you use DIY Loop why not make a video of why you chose that and what you like and dislike about it ?

[@arwaashtaiwi69]

Thanks alot for the great informations, anyone knows anything about minimed 890 g ? If it is at all launched anywhere

[@coastalrider1155]

My last 2 pumps have been compatible with a cgm and never been given one it’s an absolute joke I am now on the 780g had it about a year and abit and still no cgm to go with it just crappy libre 2 that hardly work half the time

[@GD15555]

please make an update about viacyte implanted cell pouch. What do you think? is it the future? Thanks

[@capfluff]

As always useful and essential. Your work is super helpful. Like this comment if you need closer (side by side) comparison of closed loops.

[@thomhoffenkamp]

Did I hear you correctly when you said the 780 rollout in the US will be as a software update to the 770g?

[@Nerdabetic]

No updates at the moment but it is anticipated very shortly. Just like everything at FDA, it is delayed as FDA is focused on pandemic related products.

[@thomhoffenkamp]

@@Nerdabetic Thanks, of course FDA= finally decide anything? But specifically is the 780 just a 770 with a downloaded update. Therefore, do I have a 780 already, just awaiting that download?

[@Nerdabetic]

Hahahaha that’s a good one! Well the difference between 770 and 780 is just the software so yes.

[@vicki4493]

When will omipod 5 will be released?

[@minejager1818]

They want to release it before summer in some countries but there isn't a concrete date yet. Maybe look on Insulet website

[@Nerdabetic]

No date yet but they are aiming at first half of this year.

[@vicki4493]

@@minejager1818 thanks I am very interested on it for my son we live in usa

[@vicki4493]

@@Nerdabetic please as soon as is out published 🙏I am very interested on it for my son 💙🙏😊 I live 🇺🇸

[@asmirj4534]

Thanks for the video. I think for litle children this is too much to handle. We as a parents must do all the busines. P.S. Do you have news for Libre 3?

[@minejager1818]

Not him but unfortunately there isn't any new information regarding the Libre 3. They still say "coming soon" whatever that's supposed to mean however there has recently been an update within Abbotts program for doctors regarding the Libre 3 so maybe we will learn something new soon

[@asmirj4534]

@@minejager1818 thanks

[@Nerdabetic]

No news about Libre 3 for now.

[@robertmalakuskie1341]

Not sure if you said medtronic 780 will work with dexcom or not

[@minejager1818]

It doesn't. The 780 has already been launched you can watch videos about it. Medtronic pumps only work with the Guardian sensor from Medtronic. This video is about hybrid closed loop systems which often use older pumps or pumps which don't have a system integrated already

[@Nerdabetic]

Medtronics pump will work with Dexcom via Tidepool Loop. It is not 780G but a special version of a Medtronic pump which will work with Tidepool. Hope this helps

[@blondy2061h]

I'm not big on Google but if you wanna make a video about why US places have the same name as UK places I'd watch the heck out of that

[@drizztdurden9045]

One more time many thanks for your work. @@++ ;) :)

[@Nerdabetic]

Oh thanks so much!

[@maahuuhaa]

I think I am in love with you, Nerdabetic

[@locomademoiselle]

🥳🥳🥳🥳

[@copperswirl4320]

Have you been having any adverse reaction to the Dexcom G6 adhesive glue on their sensors? I think they changed the glue formula almost a year ago and ever since then the sensors tear my skin up. If the sensor material gets wet in the shower it starts a terrible skin reaction. I’m having to create an underlay. Basically putting the sensor on top of a big bandaid and poking a hole through the center for the insertion needle sensor. What a pain in the ass! I’ve called Dexcom many times and they don’t care at all! You can Google this issue under “Dexcom sensor allergic or skin reaction”.

[@Nerdabetic]

No, I have never had any issues with my Dexcom. It has been working incredibly well for me since day 1.

[@dwightl5863]

@@Nerdabetic I have not had any issues with the Dexcom sensors either. Unfortunately we are not all the same and have to customize wherever it is required.

[@saraheart2804]

Can you appy SkinPrep prior to applying to protect your skin?

[@matthewschrock8947]

It is actually very common, I had bad allergic skin reaction to G6, the solution for me was a simple skin prep, both Medline or Smith & Neph worked equally well, as an added insurance, I also put on SkinTac after the prep. It works amazing, no nasty bumps or rash anymore, all available on eBay and WELL worth it to keep my G6. GOOD LUCK ALL!

[@goki22]

Hello everyone! Number 1

[@Nerdabetic]

hahah! thanks for watching :)

[@rhdtv2002]

So what are you on these days? Are you still looping?

[@SwissPGO]

I'm very worried about what's happening (commercial agreements).Years ago, it was still possible to design your own closed look system (e.g.openaps.org ). Pump manufacturer since then have started removing that possibility (medtronic) , and now we would have to pay to use software that sends all data back to "mothership"? And we'll have to pay a license to use the software, but cannot roll our own algorithm and keep our data private to ourself? Too bad you did not mention openaps #wearenotwaiting Thanks for this info! I'm suffering from the Medtronic Minimed 780G pump's bad software algo design and unreliable sensors. It's also not capable to communicate with latest versions of iOS and MacOS, or Linux. Greeting from Switzerland, Peter