#114

[@yakata79]

It was great when you talked about “what’s coming down the pipeline” such as plant exosomes. And why not to buy into that hype train. It’s cool to have your jaded industry expert insight. The way you guys feel about things can be a takeaway for me even if I really don’t understand all the science. Also props to Victoria for keeping the podcast going, segmenting for time, expectations. All helpful frameworks.

[@e.foster9137]

Oh yay! Thank you for making an episode dedicated to this. Gonna check it out!!!

[@lyssl6713]

Plated unexpectedly resolved a very serious scar on my face. I wasn't using it for that purpose. The scar is from when I was a kid.

[@mosquitosho蚊]

Wow! I watched this video and saw your comment 4 days ago and immediately went to buy Plated Intense Serum the next day at my dermatologist’s office. I only used it 3 times so far and my little wound around my eye area is finally healing. The little wound was caused from a procedure 3.5 weeks ago and for some reasons it wasn’t healing well. Anyway, thank you for sharing your experience and it saved my little wound because I would never spend that much money on a little bottle of skincare product!

[@johnnyarellano7653]

Gloria You are soooo spot on. At the the time mark 34:38 I bought the Neogen Dermalogy High Exosomes Cream and on both front the back of the packaging it says “Exosomes by Cica” and “Exosomes Extracted from Centella Asiastica” 😂 I wasn’t buying it for the exosomes. I mainly bought it because I was on the market for a gel moisturizer with peptides and antioxidants for daytime use and the price was really affordable. But you were so right about seeing “plant derived Exosomes” 😂😂

[@ChemistConfessions]

haha your purchase reasoning is solid!

[@monicachavez2737]

Can you please do a video discussing the potential of tretinoin/retinol to cause dry eyes? It may not have been studied but there are so many anecdotes out there, and I would like to know if there is any theoretical reason to be cautious. For example, even if you avoid the eye area when applying, is it possible that it is absorbed by your body and then affects your eyes, or can it migrate in the skin to reach your eyes? I’ve heard a lot of people say that.

[@ChristinaMJesse]

Such an interesting episode! Would love to know your take on the formulation of the Reviv Serums Ultimate Serum.

[@victerpenate6201]

Thank you for the valuable information!!!! Keep it up 🎉🎉🎉

[@DrReedB0928]

I LOVE your podcasts!! As a physician, I feel like I am back in medical school (but more fun). When you have time, information on skin care for people with Ehlers Danlos (like myself) would be unique and well appreciated. Thank you!!!!!!!!

[@jonathanbrook5689]

Is there any research on exosomes/conditioned media for hair loss? Thoughts on Neogenesis and Anteage? Are they credible sources with exosomes? Thanks

[@sprrringtime]

Hello! Do you have any video about Reedle based skincare?

[@ChemistConfessions]

this is on the list!

[@sprrringtime]

@ Thanks so much!!

[@TrishBishop-ll3gy]

I was just about to purchase a micro needling device…I’ll wait awhile. Thanks so much for this!!

[@ChemistConfessions]

nooo....leave it to the professionals. those in-office needle lengths are way more effective

[@db-gb5xi]

I wonder how this compares to human growth factors or dna repair enzymes? I would also think that yes, derivatives will be coming (aren't some human growth factors genetically engineered in labs?) and I have no clue about how dna repair enzymes are sourced.

[@ChemistConfessions]

your guess is as good as ours. we would honestly lump all of these in a category of "fancy science - waiting for more data"

[@nthabisengsello6428]

Hey guys, love you content, can you do a deep dive on Panthenol?

[@ChemistConfessions]

yes! a classic!

[@yakata79]

Also I really enjoyed the animal fun fact this episode. Even though it was part existential horror it was also uplifting and nice to have something that can be done for the frogs. Giving them saunas.

[@ChemistConfessions]

we need to do more uplifting animal fun facts lol

[@WaffleRedondo]

So my Sooryehan Black Serum is useless?!😮

[@ChemistConfessions]

definitely not useless! but we're guessing maybe not relying so heavily on the exosome part

[@SarahHLeslie]

Can you talk about exosomes? Growth factors, as it relates to cancerous cells OR cells that attack themselves as in autoimmune diseases that many people have. Sorry, I realize that's a pretty loaded request, but I imagine could dictate outcome - especially with those with body Psoriasis.

[@ChemistConfessions]

would probably say it's way too early to correlate exosomes to psoriasis therapy

[@ainakunigelyte]

I would love to hear the next dive in of Growth factors in general, people keep swearing that Allies of Skin 200 dollar EGF factor tighten their skin and I wonder if that is backed with science? KZbin Hot and Flashy made an extensive video going through many research papers on the topic and says that there is no good evidence from the independent studies --> kzbin.info/www/bejne/anyUd6V8i9GLhcU

[@e.foster9137]

Now that I had time to watch the whole thing, I had some reflections. The penetration thing was a huge insight. And for sure the biggest anti-aging results we’ve seen anecdotally in people is when used during/after in-office procedures. For topical use I think there are huge promises but not exactly anti-aging which requires penetration to the fibroblast - the biggest promises for topical use seem to be for skin conditions such as superficial scarring, rosacea and other types of inflammation on the skin - but these claims will take longer than the cosmetic ones to get approved. Thank you so much for diving deep into this - I’m gonna save a lot of money because of it 🥹💙