16 Years: Surviving Metastatic

[@jeetujeet27]

A ray of hope for metastatic prostate cancer patients ❤ lots of blessings and love

[@jeffreyphillips4182]

Happy for you but I have stage 4 prostate cancer, metastized into bone, bladder, left lung, liver. Been fighting this for 9 years but each 6 months I get a little weaker and weaker. PSA is now over 100 regardless of all the treatment. Don't know how much time I have left, I'm 74, got this from Agent Orange in Nam. We shall see how much longer I have, but not worried about it at all. Not afraid to die because I've lived a life already. Can't live forever 🥳

[@MrNimaYamini]

Be strong and enjoy every day it’s a gift in your 70’s ❤

[@patricegunzelle2687]

I am amazed of your strength,cancer is not a dead sentence indeed as it fights we need to fight back aggressively.

[@RdeKlerk-sx2yx]

Fenbendazol an option ?

[@hyperlinkphilosophy]

You’re strong. Keep at it. And God bless!

[@elenadianamateiu]

What is your treatment for bones?

[@christophergwala5531]

Thanks for reassuring " it's not a death sentence". That gives me reason to fight on. Thanks for sharing.

[@myyoutubechannel3161]

You will 🙏 keep going 💪

[@J.Paul2023]

I heard corrosol fruits were very good to combat this cancer and what does work also is cutting out all sugar, coffee and meat with the exception of fish, just vegetables no additives whatsoever to rebalance your ph.. Also look up on youtube "What 1 teaspoon of ginger did to cancer cells"!

[@J.Paul2023]

@@GarrishChristopherRobin777 Try reading the book of John, Matthew, Luke and Marc, you'll get to know where life originated from, it could change your point of view!..

[@peterllewellyn8835]

Good video. Am in year 13 with my metastatic prostate cancer from a PSA of 37 and Gleason of 9, so it’s indeed all about management and control, staying positive, diet and working proactively with your medics.

[@ahuyldrm]

Did you get chemo. Best wishes for you ⭐ I don't understand psa levels. Does it mean higher psa levels are worse? does it mean more bone metastasis or sth else

[@beebeeramone4641]

What was your psa free number

[@zoeclan2044]

@@beebeeramone4641unfortunately for some psa doesn’t matter :( especially if it’s castrate resistant.

[@gulshani8331]

Are u alive?

[@charlesgair8608]

4 Cancers. Man I Can't Imagine Going Through That. Good Luck To You Man.

[@Wreckbeach400]

I'm 81 years old and have had prostate cancer for 22 years. I had external beam radiation for 35 days. A year later the cancer returned so started intermittent hormone reducing therapy with a drug called Zoladex. My original Doctor retired and a my new Doctor injects Zoladex every 3 months. My PSA has remained steady for the past year. I'm a lucky guy.

[@caroletta451]

Blessed by God, I would say!

[@PEACIYTALKS]

What stage was the cancer? Because my dad is also having same issue

[@mikewood5679]

81 you lucky man

[@pmm2806]

So glad to hear you are ok… and what do you eat? My dad has same cancer, after 6 yrs in pills treatments ,he will start I.V. Chemotherapy in a couple days, his cancer the doc, said is out if control, He have been eating eggs daily & carbs, not hearing my suggestions of not eating that, so now i want to know what menu he needs to have, to be strict with him, greetings from Mexico🇲🇽

[@benplant286]

Hello, my father has prostate cancer also and we’re running out of time. Can you please tell me what you have done to beat this cancer? Would be so appreciative if you could take the time to explain it to me. God bless you sir 🙏🏼

[@awshortclips]

Two years ago, at the age of 53, I had my prostate removed, and so far no reoccurrence. I appreciate this video, especially the last few minutes. We really do need to take charge of our healthcare.

[@Shubham_12344]

@@awshortclips Do you have any urinary problems?

[@awshortclips]

@@Shubham_12344 Hi. Shortly after surgery and for maybe 8 months later I had trouble with incontinence. It eventually went away. The majority of the time it is manageable. Sometimes it sneaks up on me. I suspect based on what I eat and drink prior, it can affect the urge to pee. In fact, we were in Florida's Universal Studios in the Harry Potter restaurant. It was sweltering outside so I was guzzling water. Earlier in the day I drank two cups of coffee. Guess what? I flew out of the restaurant, looking for a restroom. It was pretty bad especially due to the crowds and my unfamiliarity with the place. I made it but...lesson learned.

[@forthemusic9875]

Great to hear your positivity after going through so much. I live in the UK so it's possible that treatment is a little different over here. My friend age 69 was diagnosed with metastatic prostate cancer about a year ago. He had a PSA of 150 and after an MRI it was discovered that the cancer had spread to the bone. He was told to expect the worse as there was no cure. He has been given two treatments. 1) a 6 month hormone injection of Decapeptyl and 2) Monthly tablets of a novel hormone treatment called Apalutamide. His PSA has gone down to 4 and he is generally in good health apart from frequent sweats. It is giving him some hope that the future might not be quite so grim. When I showed him your story, it has further given him hope, although the medication is different. Although Apalutamide does not promise a cure, if he can survive another 5 years it's looking as though the new personalised mRNA treatments may offer some hope. Thanks you for sharing your story and thanks also to the researchers, doctors and nurses who literally are saving my friends life

[@ahuyldrm]

Best wishes to your friend. I hope he will win this battle. Haven't your friend gotten chemo?

[@forthemusic9875]

@@ahuyldrm No he was offered Apalutamide instead of chemo , so he took that route . I'll pass on your best wishes thanks

[@ahuyldrm]

@@forthemusic9875 thanks for answer i hope your friend will get well soon🌸

[@LearnEnglishWithPallavi]

@@forthemusic9875 hi my father is suffering from same. But they didn't give any harmone therapy. Now they are giving chemo. May i know more about your friends treatment it might help us. Plz

[@MyCousinGrandpa]

What an amazing testimony. This man has a gift of positivity and showing others the way.

[@n.c.b.8832]

WOW, absolutely love this guy and his attitude, thank you so much

[@mangomd]

Alex, you are a true asset to PCRI. Your knowledge of PC is amazing and I love your interviews and your questions to Dr. Stoltz.

[@dirkl9652]

I second your comment 100% !!!!

[@nesssssa23]

My dad (59) got diagnosed last week with stage 3 prostate cancer, metaswized into bone and bone marrow. Today was his first dose of treatment and main appointment with the urologist. the past week from finding out of his diagnosis I have been a wreck as I am not ready for him to got (me 24 f). Videos like these give me hope so thank you for sharing your story

[@teresa9760]

I am not a Doctor or professional medical person. I am only a wife. As a wife of a Prostate Cancer man, please first DO NOT BE PUSHED INTO FEAR: 1. Any Doc or staff that tells you "Dont go on internet", show them this video. Get this gentleman's calm attitude and talk in your words! Do NOT ALLOW OTHERS TO TELL YOU NOT TO EDUCATE YOURSELF. You HAVE to be your own advocate. 2. Stick to reputable sites like PCRI, UCLA, MAYO, Wikipedia, Yale, Stanford, and Sites that YOU GROW TO TRUST thru first hand experience. Example, I trust PCRI. I trust Dr Eric Berg KZbins, i trust Kidney Warrior Dadvice youtubes. I LOVE PCRI and watch as much of their info as I can absorb. 3. Get a 4 inch thick, three ring Binder. Keep everything in date chronoligical order. KEEP ABSOLUTELY every paper, personal notes, statements, tests, labs, CD of imaging from day one! I also wrote TEST and LABS i find online to request running on my husband. I caught our initial uroligist in far too many mis-truths and his staff flat told me, "You dont get to have all your questions answered!" I said WHAT!!! And she repeated it 3 times. (Now FIRED). Take notes, date, time, attendees in conversation, titles of position, Doc, Medical Assist etc. Be able to read back and understand everything many years down the road. 4. LEARN your cancer "STAGING" right away. And I am not referring to Stage 1 thru 4 here. Get your specific Cancer's exact, COMPLETE STAGING. I just asked my husband's original urologist what is the STAGING of my husbands cancer. He said Stage 2. First, THAT IS NOT TRUE IN HIS CASE. Nor the answer to my question. Second, That answer is NOT COMPLETE. Look up Cancer "staging" in Wikipedia to fully understand the difference in STAGING and STAGE 1-4. My husband is NOT a Stage 2. His STAGING IS: T2aN0M0 Stage 3A High Risk, but curable, Prostate Adenocarcenoma, PSA 50.9 with Gleason 4+3=7 with a lab test called "My Risk" Gene test of negative for known bad Genes. Decifer Test originally said there were 2 bad DNA/gene issues but NO doc could answer WHAT his high risk bad DNA WAS. It was a mis-truth as i forced the GENOM TEST CALLED "MY RISK". The test put me at ease when i learned it was NOT EVEN TRUE that my husband's cancer was not, in fact, a BAD BRACA GENE, ETC. After 6 horror sleepless months, we fired original Urologist and now have a MEDICAL ONCOLOGIST and a RADIOLOGIST ONCOLOGIST, and CARDIOLOGIST. Now that i understand my husband's "STAGING", I can understand why Doctorz selected the Treatment Solutions. I learned this "STAGING" info, which they acted indignant that i wanted to understand. This info put me at ease to know, I am beginning to sleep better. Now i had a way to watch the videos at PCRI which apply. 5. Get WRITTEN ON PAPER explanation of ALL "SIDE EFFECTS", and ALL "QUALITY OF LIFE" exepectations from ALL TREATMENTS. Our orig Urologist told us only the few easily gulible answers. Doc withheld the REAL answers from me. We learned the hard way that there is a vast difference in the wording. SIDE EFFECTS. ASK ABOUT NEXT 10 YEARS "QUALITY OF LIFE" from each medication and Treatment. My husband had No Side Effects from 4 days of ADT. Day 5 it bearly killed him from some depleted electrolytes and unknown heart issues. How about checking FIRST. OUR uroligist told us it was not necessary! 5 days later, he was near dead in hospital 2 days. 6. Do not get pushed into anything that your gut/intuition says doesnt feel right, until you get answers. I am not a doctor, this is only my opinion based upon my experience. 7. Keep a good TEAM 8. DO NOT ALLOW ANYONE TO FEAR MONGER YOU. Ask your Docs how much time you have for SECOND OPINIONS. DO NOT BE AFRAID. THE TREATMENTS ARE SO MUCH BETTER NOW A DAYS.

[@Its2025]

@@nesssssa23 best luck to your father! Look into Thomas Seyfried. He did 30 / 40 years research on cancer and might give some good insights!

[@craftrunner]

Fantastic video, thank you both for the great support. I have stage 4, it was diagnosed on the 2nov 23. I have been put on a hormone treatment and it seems to be working. No more pain in my bones or hip. Fingers crossed. My lovely wife is super supportive and is researching everything, and all the anti cancer food which might help. Totally agree you need to know what things to ask your doctors. I have a printed form with about 50 questions to help get the feedback from them. Yes you need to understand your cancer. Keep up the fantastic information and support. Regards Steve

[@claudiafinelle]

My husband has been on ADt for two years, also stage 4. I think the plant based diet is helping also.

[@gitz4411]

My Dad was on hormone therapy for 2years after that it didnt helped now he is in Second line of treatment, Aiberatetone was suggest for hormone therapy let me know which medicne are u been suggested Also adivce company brand also matters while taking medicine bcoz in todays market there are many startup and large markets sell aiberaterone with difrnt company

[@roming6722]

@@claudiafinelle hi I have the tummy implant it is working very well. I am also following the New Mediterranean Diet plus adding the cancer fighting food. It is working all my pain in my bones has gone. Although I do have hot flushes. Much to my wife's amusement 🤣

[@claudiafinelle7252]

@@roming6722 Thats great! Exercise seems to be very helpful too. Yeah,the hot flushes are no joke! Good luck to you, to all of us.

[@ahuyldrm]

My best wishes for you. Haven't you gotten chemo? My dad: bone metastasis is getting hormon therapy and chemo at the same time but his doctors said "don't panic we should trust each other". I don't know what to expect i am so nervous. He has a catheter because after his first chemo he has had trouble urinating.

[@rakeshgrover7435]

This is super helpful and full of vital information, coming from a person who has actually gone through all this and is so positive about the whole thing. In today's age, we have to be thankful to the internet and the loads of information available. Thanks sir!

[@billybaroo5445]

As usual, extremely informative. You can't stress enough the importance of doctor patient communication AND research/self advocacy.

[@dwmcever]

72, stage 4 for 2 years . PSA has been 0.02 since radiation and Orgovix 14 months ago. Last PETSCAN clear. Testosterone near zero, have lost muscle mass and body fat.. down to 205lbs. Little or no red meat. Side effects my type 2 diabetes harder to control, controlling it is main reason for weight loss. Arthritis is a bit worse but controllable. No Sex drive, but strangely does not bother me or my spouse.

[@sam0091able]

my father, 76, diagnosed prostate cancer last week and schedule for a bone scan, we still hope that the cancer cells don't spread, we earned below average and we have lack of health facilities in our province you have to travel miles away for a good hospital, what we are praying now is that my father will not suffer so much in pain, i put my trust in God

[@bilbosoze7341]

@@sam0091able enzalutamide, half a dose or 80 mg daily for 6 wks, then a month off. If he can take testosterone injections on his month off it helps to kill more cancer. Then back on the enzalutamide. This is called sequential therapy... Love and best for your father. Google.

[@bilbosoze7341]

Enzalutamide from India..very inexpensive

[@bilbosoze7341]

This gentlemen is an inspiration.....I have done like him for 11 yrs. Researched for myself....changed medicines....changed doctors if needed....refused exoratory surgery.....etc..etc.. Great video

[@roger1uk676]

Alex so loved this post! Joel having all these different cancers, surviving and handling it so well, not miserable but adjusted to his condition and looks so well and happy! And patients research is vital and after 2 years i am still learning! Every post is gold, and your caring dedication keeps me well! Thank you as always!🙏

[@newsreelrussia3693]

He has money he is a CEO.

[@rudysims7386]

Would have liked to heard more about his diet, but anyway for those that is battling cancer go plant base as much as possible, and go light on the sugar,as well as dairy,you pray for me and l will pray for you... Peace.

[@luketoni2902]

Yes, thank you for this post, Alex and Joel! We need more information provided by actual/real individuals living with/ surviving advanced PC. I have learned a lot from PCRI over the past 2 years. It is rare, however, to hear from men dealing with this condition ( advanced PC). Best wishes!

[@io3010]

Thank you for sharing your story, you are a survivor and an inspiration for us all!

[@nijaydosslin4720]

Amazing! You are 2 steps ahead of the doctors

[@steinshaw2490]

Thank you. In 2016 I started my cancer journey with a PSA test at a health fair that ended up at 48 or 50 at the age of 50. I was at the mercy of my team but I believe they are a good team. When I first got my adt vacation I learned my doubling time was just over a month. Very long story short the information PCRI and other sources provided me allowed me to change teams (one that would utilize the Axumin scan). My original team wanted me on Lupron prednisone and Zytiga (the triple play) until it stopped working. This last May I finished more radiation and I’m thinking they got the last of it. I’ll be on the triple play for a total of 2 years. I’m expecting to be able to stop adt and I’m hoping forever… time will tell.

[@nicolinogiancola9644]

Excellent content. This young lady must be a trained journalist. she is a great interveiwer.

[@zpoedog]

I am 85 and found out 2 years ago had Prostate cancer with Gleason 9. It is nice of you to make this video. So far I have done nothing. Time to make some choices!

[@Debijo7]

What is your PSA?

[@zpoedog]

@@Debijo7 My PSA is 6.160 and my free PSA is 0.592. What is your opinion?

[@zpoedog]

I am a healthy 85 year old. My BMI is 22 and I eat mostly plant based. (no meat) I exercise and walk every day and am taking Yoga classes.

[@Debijo7]

@@zpoedog my husband is 80 and as it is on Ellegaard and Xtandi year and he is supposed to be starting radiation for five days a week five minutes a day for seven weeks. I’m very concerned about these decisions, but I don’t know what else to do. As far as your case, personally, I could not imagine not doing anything considering where my husband is at. If you have a PSA that means that your body is making the antigen to the cancer. What comes out of the cancer that’s how a PSA is measured by what the cancer makes. So something is going on in your body yeah I think if they would’ve caught my husband’s cancer before it got so high his PSA was 27. Before surgery and after surgery went to 18 and then it went up to 24 so long story short they started putting him on the Ellegaard in a couple months later he got on the Xtandi yeah my whole point is if it had been caught sooner, we could’ve done different things instead of having to have a radical process to me my opinion is that you need to first off it depends on what you want to do if you don’t wanna do conventional medicine, I suggest you go on a fast and then start eating only good food and drinking. There is a guy online that cured himself of stage four cancer by diet. Well let me correct myself he’s not cured, but he has given himself four more years of life where they gave him two months.

[@Debijo7]

Have you done any research on your prostate? Do you know what a Glisan nine means?

[@dankasper5104]

Great to see and hear you Joel! You are one of my PC heros. I was so excited to meet you a few years ago at a PCRI Conference in LA> You were there with your wife and another of my heros Todd Seals. You gave me hope and you are definitely an Inspiration. Thanks for all you do, to your dedication to research, communicating info to us all. Thanks much for your weblinks. You are definitely an "outlyer"". Love that term. Love you Brother ! Keep the Faith!!!j

[@BashirAhmad-eh9ec]

I have prostate adenocarcinoma, Gleason grade 4+3, score 7/10, group 3, what I have to do

[@michaelclennan8425]

Joel is a very hard working and intelligent person. He is educating his doctors. The doctors only know what was taught in medical school and follow approved protocols. They know the approved procedures to remove a prostate.

[@mikeoniones667]

You are a welcome site buddy I'm metistatic 4th stage castration resistance. Pc.

[@eddiegardner8232]

Doing your research is very important when it comes to treatment decision points. PCRI has been very important to me as part of this education process. I read clinical research trial studies, and watch the Grand Rounds of Urology lectures. It all helps when planning your PC journey.

[@allenantrim3676]

My PSA was 1599 at the start with most bones infected, and now am starting into my 6th year and feel pretty good--most of the time. I try not to let this cancer be my life, just a little thing, along with the rest of the little things that I have to deal with.

[@sam0091able]

what is your medication?

[@allenantrim3676]

@@sam0091able has always been Lupron shots, a bone shot every three months (Xgeva). Then pills. They started me on Cosodex but switched me to Zytega for a year. I then went to Erleada, which I have been taking since. So I have always been on pills the whole time. The Erleada gave me the mother of all rashes, I didn't tell the bone guy as I thought it was part of the deal. I found a lotion at Manards that eased the itching a lot. When I told the doc about it the rash was nearly gone--had I mentioned it when it started I think he would have wanted to port me then. I eat lots of calcium and vitamin D. They never said, but I drink lots of soy vanilla milk, the urologist, when I told him said to keep drinking it. I had a Pet scan a few weeks ago and it looked very good.

[@allenantrim3676]

@@sam0091able Did my reply come through?

[@allenantrim3676]

@@sam0091able I will reply again in case some one else is curious, my reply did not show up on my computer. From the get-go, 4th stage cancer, it was Lupron, no breaks, same with pills. First Casodex for a short time, went to Zytiga for a year, then Erleada till now, and Xgeva throughout the cancer. Calcium and vitamin D. I drink a lot of vanilla soy milk. The Erleada gave me the mother of all rashes for a time. I did not tell the doctor as I thought is part of the deal. The only product I found to ease the rash was a Watkins lotion from Manards. Had I told the doctor I think he would have ported me, so that worked out well. By the way I had a Pet scan a few weeks ago and the prostate at that time was disease free-from a gleason of 10 and most of the cancer seems inactive.

[@mikealaninspires]

Love you man you are an inspiration to us all who have this disease power to you stay strong!!!💯🦾🙏🙏

[@topmarketvalue615]

Thank you Alex, for giving us this type of perspective! Thanks

[@joeyburrell3207]

Joel is one of those people who every person whose afflicted with this enemy should be listening to. These are heroes who gives the rest of a positive mindset as we fight this battle. Super duper important to incorporate a can do it attitude. Especially, during all the negative no walk in the park side affects. I just want add, stay far away from negative care givers, another vital factor. Always try to remember the mind body connection. Try to keep it on your side.😊👍👍👍 P.S. 🙏 too. They can be powerful in the mind body.

[@shywatching]

What was you diet like during this time? Did you make any changes?

[@dcplunkett]

Another good one. Thanks.

[@sgtbosshog2182]

Blessings 🙌 your story was amazing. Thank You

[@duposflies2621]

It eas me about it what he said theres a hope even your cancer already spread. But I think it depends what your body react to your treatment. Be positive too, be strong. I just had my prostate needle biopsy and still waiting for the result and my bone scan too because in my mri they saw 2 tomur in my prostate and one in my bone. But my psa was only 3.8 and I'm 62 this yr. The only thing I'm praying for is that Before I go I want to see my son turn 18, so he can understand whats going on, he is 12 this yr. Thanks for sharing its helps us a lot

[@stephengathungu3454]

Glory and Thanksgiving to our maker,you will be cured.1/ toxin's to stop and avoid: all refined sugar, pesticides, herbicides, high fructose preservertives Nitrites GMO microwave foods MSG margarines vegetable oil soy products Diet and artificial sweeteners colors processed oils, reduce grains, lectins.

[@stephengathungu3454]

My Lord my God, Before you go for chemotherapy:: NEW research 100 times better than chemotherapy and more effective than chemotherapy kills cancer stem. Take 1/2 teaspoon to 1 teaspoon of Dry Ginger not fresh ginger less potent daily dose, Don't heat above 85 degrees .

[@abideinchristjesus123]

zinc levels help, with other minerals, vit. D, and tomatoes - I hope you a healthy recovery in Jesus Christ name.

[@pauljohnson7770]

Great content. Drs are great but human. It’s your job to learn what you can.

[@hopeisit1347]

My dad has just told me he has stage 4 prostate cancer..Waiting on MRI results..im so scared I can’t live without him

[@peterklus]

Terrific Interview. My heart goes out to Mr Nowak. What courage in the face of adversity! As I start my own PC journey, I am inspired by his example. Dr Sudevan Wisconsin

[@colemant6845]

Great information AGAIN... Thank you! So Educational for us still suffering.

[@tonysaid6184]

Excllent interview very positive and supportive. Thanks

[@Lanceanddian]

I have a psa 47 Gleason score of 9 I was going to have the surgery till I seen this video thank you I think now that I'm going to live with it

[@ricknowak4582]

@@Lanceanddian I am so glad for you brother! I sure would like to hear your story. I am 70 years old and have a Gleason score of 3 + 4 = 7 with a different percent volume from two different opinions. The first one wasn't too bad! 5% volume one was 30% though. 5 out of 10 cores. Second opinion from Johns Hopkins comes back..... 40 and 50% volume! Wtf! I am waiting on a third opinion. I don't really want to do anything. Thoughts please I will sure would like to hear more details on your decision to quit any treatments.

[@barbaratankersley7117]

Thank you so much for sharing Was very informing

[@alanblanes2876]

What a terrific interview!

[@johnston378]

Thank you

[@mr.ronaldlawrence1231]

This information is hopeful and helpful.

[@unknowndriver6652]

Unbelievable he went through a lot

[@zoranjovic2184]

Not all heroes wear cape. Amazing story

[@andimcgaw]

I'm so glad for you. I have metastatic prostate cancer and I'm suffering badly

[@anilmehta6425]

Turmeric 1/2 gm + 2 pinch of blackpepper in warm milk ...have slowly ..relieves pain feel lively ...Also apply externally turmeric mixed slight oil....

[@RdeKlerk-sx2yx]

​@@anilmehta6425fenbendazol?

[@edingram814]

Praying for you my brother°°

[@Abieee4725]

My dad has stage 4 postrate cancer and his at the moment paralysed, losing his voice and constantly in pain. All treatments have failed and now I’m just very confused and concerned what next for him

[@Prog-t9d]

Thanks for sharing

[@Zey909]

My dad is 86 yrs old . Recently he diagnosed silent metastasis prostate cancer 3 rd grade . He had a TURP . After that he still have severe pain off n on . He did pet scan. He started getting pain and shrinkage of ureter , now doctor suggest to do stent to put in ureter . He started incontinent of urine . I don’t know . God please help . He going through a lots of pain .he is having evry 3 month hormonal therapy injections. Tab 2 abiraterone once a day and wysolone once a day .and with pain killer and tamlocpt . Doctor said my dad can’t get normal . Atleast if he won’t get pain . I would somehow satisfied . So stressful when cancer cought

[@Iamwhoiam28]

My husband is going through the same things. So much pain and same medication. Had to stop meds. Too much. Tremendous weight lost. Can’t walk. Foley catheter keeps developing uti. Leaking.

[@Mrgaurav1432]

My father diagnosed with 4th stage metastatic prostate cancer 1 year ago with Gleason score 8 PSA levels at 3300 in the beginning. Doctor removed testicles immediately. And started bicalumutide 50mg. PSA decreases drastically below 4. But bicalumutide stopped working after 8 months. PSA started increasing to 10. Then doctor prescribed enzalutamide. It is working very fine. PSA down again to 0.08....almost zero. Now father is feeling very well. Trying to remain physically active. Also getting physiotherapy. Everything is going well now. But i always have concerns about the future. How long the medicines works??

[@pankajb3214]

@@Mrgaurav1432 what was the PSMA PET scan result of him? Spread area?

[@kendavis1198]

Outstanding!!!

[@lesyab28]

Hello. Thank you for video. I did not understand names of medicines except Lupron. Maybe someone could help and write which medicines were named. English is not my native language. Thank you in advance.

[@maverickat4544]

Wonderful story! So encouraging for us in the metastatic boat

[@scottcraig2727]

very encouraging

[@markiesmith4537]

Sorry I don't understand if his metastatic reoccurrence was in the bones or soft tissue (typically the lymph nodes) . Both areas involve different treatments and outcomes....Did I miss something? Otherwise thanks for your story.

[@rogerembry4777]

My my doctor told me that people who stay on harmony’s live longer then people who do it intermittently

[@fatmaschindley2516]

I hope everyone gets cure at some point from this terrible disease. I seeking an answer to side effects of the Lupron shot. My husband suffers terribly from it. He has severe fatigue reaction to it. And he is in the bed can’t do much anymore. I’m bagging anyone to answer me, is there a remedy for this? I am praying for all the people who suffer from any kind of illness. Can anyone help me please?

[@ThePCRI]

Hello Fatma, we are sorry to hear that your husband is suffering. Here is a video we did on hormone therapy side effects: kzbin.info/www/bejne/e5Ddi2CifJuYm7s Please reach out to us via our website, www.pcri.org/helpline if you would like to talk to a prostate cancer patient who has been through hormone therapy and can give you information on the process.

[@bobbennett5013]

Another excellent informative and encouraging video. What really grabbed my attention were Joel's comments on Orgovyx/Relugolix (O/R). The general response to O/R's FDA listing was pretty muted - a bit "ho-hum': "yes, it's good to have a pill for people who don't like injections". That seemed to gloss over the fact that the Lupron injection sometimes produces a PSA flare (mentioned by Joel) but also could produce a benign but concerning tummy lump at the site of the injection. A small published study also suggests that O/R drives PSA down faster and (sometimes) further than Lupron etc. This might be important because a lower PSA nadir seems to be correlated with a reduced risk of relapse. Lastly, O/R stops working from the time you stop taking it. That would seem to be a plus in those instances where you might want to stop the treatment immediately rather than wait for the effects of a 3, 6 or 12 month injection to wear off. Food for thought. PS, Like others, I'm a bit baffled as to why Joel didn't undergo post relapse radiation therapy.

[@ga6589]

My husband was diagnosed stage 4, low volume metastasis 20 months ago. His Mayo Clinic oncologist recommended he start with a Firmagon injection, which does not cause a flare. His PSA dropped like a rock from 24 to 2.0. A month later he started Lupron (every 3 mos.) in combination with Zytiga. No flare. His PSA dropped to negligible very quickly and remains so today. (He also had 26 rounds of radiation early on.)

[@tardisbob2745]

Hi I think some people get a flare with Lupron and some don’t. The claim made for Orgovyx is that no one gets a flare. I had a similar experience to you with Lupron being used in tandem with Zytiga/ Abiraterone. After being on Lupron for 2 months I was prescribed Abiraterone as an add on. The PSA dropped to 0.04 after a further two months. The peak prior to Lupron was 16. These results are consistent with the STAMPEDE trial findings in the UK published in late 2021.

[@Tony-xj5mr]

I’ve had my pre op today for my surgery on Saturday to have a tumour removed it’s on my bladder and spread to my prostate it’s basically covering it I’m having a resection if anyone can give me some information on how I will be after the surgery that would be great, it’s basically the size of a egg they say and it’s worried me so much, I’m only 49 I’ve had bad symptoms for over two years tho I was peeing blood on and off and I put it down to urine infection, witch I was so silly to think that. I ended up in hospital 3 months ago due to blood clots building up in my bladder to the point I couldn’t go to the toilet it was fully blocked and was rushed in the hospital 8 days of pure pain as the first day they struggled to get the catheter in due to my prostate being enlarged, I also get incontinence through this as when I go to pee I can’t fully empty my bladder due to the tumour covering my urethra partially. I’m so scared as I’m only 49 and have 4 great kids who live with me I’m a single parent u see im lucky though as they are grown up to ages of 19-18-17 last two are twins its not hit them properly yet or myself it will be when I have the biopsy done and have the results.i even had the finger test on my rear end back in hospital and they didn’t find anything then I’ve had mri last week to check my pelvis I’m just hoping that it hasn’t spread to my lymph nodes I’ve looked up on how much time I may have and it’s saying roughly 5-15 years, I’m not ready to go yet to heaven my kids need me I lost my mom and dad years ago my mom brain cancer and my dad heart attack so I need to stay strong for them as it messed my life up when I was 17 when my dad died this video has given me hope knowing this so thank you so much for putting this up god bless u all who are dealing with this illness 🙏🙏🙏

[@zoeclan2044]

What about for bone Mets? Dedifferentiated cancer? My dad has done hormone therapy Lupron and abioderone then 8 beam radiations and two doses of chemo that made him really sick. It spread to the femur now from the hip joint.

[@DCGreenZone]

>>Undetectable levels of Prostate Specific Antigen (PSA) have been reported from the first patient with metastatic castrate-resistant prostate cancer (mCRPC) to ever receive two cycles of Clarity’s 67Cu-SAR-bisPSMA at the 8GBq dose level. PSA is a marker of tumour burden, clinical response to treatment and an indicator of the recurrence of disease for prostate cancer.

[@sudhirbudhwar5254]

फोर्थ स्टेज में क्या दवाई ली है जरा बताने का कष्ठ करें

[@Lanceanddian]

Hey Joel it's Lance ya mine psa 3 years ago was 21 my family doctor told me to go in so I did and the urologist I saw said it must have been something else cause he found nothing 2 years later my psa was 43 and I went to a different urologist and he said I have aggressive metastatic prostate cancer

[@jdapina]

🙏🏿

[@mikeoniones667]

I am on Nubeqa pc hormone resistance

[@AnilMehta-mf6vg]

He was on intermittent harmone therapy n it kept him harmone sensitive.......

[@johnjarvis2346]

Thank you Alex! Did this gentleman have radiation and/or chemotherapy?

[@victorlionelnazaire685]

The patient CANNOT leave everything in the hands of your doctors ! Educate yourself on your cancer !

[@elitetrader5468]

How did he miss the chance for salvage RT? Seems crazy for his PSA to all of a sudden be 87 after being undetectable. Where's the monitoring?

[@ricknowak4582]

If ADT starves cancer then why do men have to go through surgery or radiation.

[@Skwarek-wp8dc]

Good business... for some

[@pegstair9522]

Have never seen any info on de novo treatment for stage 4 gleason 8

[@michaelanthony386]

❤❤❤

[@Mary-bx8gd]

After Listening to one of your podcasts Mr. Novak, you’re guest Dr. ken Pienta, painted a very grim and devastating opinion about Oligometastatic prostate cancer. His opinion, is quite the opposite of Dr. Mark Schultz. I enjoy your Podcasts as they are beneficial to those of us who need them, however, this is one that I don’t think anyone should listen to! We all need help, and this doctor left none!

[@RajatKumar-hk6ff]

My Father 60, has been diagnosed with metastatic prostate cancer last year & hormone therapy (lupron) is going on for him. PSA levels have been reduced significantly. But he is having consistent pain from shoulder to arm. Although we are giving pain relief tablets as well.. but I don't see much improvement in pain relief. Any suggestions?

[@ahuyldrm]

Good luck and best wishes. My father is 64 he is taking hormone and chemo at the same time. His belly and arm were aching before chemo but he got first chemo and now he seems fine with his belly and arm thank god. But i don't know what to expect in future. What was your father's psa level?

[@abideinchristjesus123]

I have heard Provenge therapy may help with stage 4 in the bones.

[@ajayzarekar270]

Do radiation therapy it is help full for reduce the pain of bones

[@anilmehta6425]

Turmeric externally oil mixed lot amount n internally 1/2 gm n 2 pinch of blackpepper in worm water....relives pain n reduces tumour size ..surely

[@ekambaramnirmala4489]

😢 ede​@@ahuyldrm

[@Lanceanddian]

Now the urologist said the other doctor only took samples from 1 side of my prostate and he should went all the way around it but now my Gleason score on one is 3×4=7 and the other is 5×4=9 and I went to the oncologist and he said he wouldn't do radiation therapy unless I have the surgery cause it's to aggressive and I'm not ready to up my manhood

[@koof1776]

👊🏻

[@daveaultman7688]

Very little details on his actual staging and spread that he claims was metastatic. A couple of lymph nodes? Local or distant from the prostate area? It just doesn’t sound like he had that serious of a case. Good for him, but for those of us with actual spread to to the spine and leg bones this video doesn’t seem to provide any real hope.

[@abideinchristjesus123]

I heard Provenge therapy may help if its stage 4 in the bones

[@Mcpbab]

My son (42 and the time) was diagnosed with Advanced Metastatic Prostate Cancer, Gleason 10, with large tumor in bladder and 7 bone mets, 6 nearby, one in shoulder. That will be 7 years in January. He had surgery to remove enough of the tumor from the bladder to allow urine flow, 6 rounds of chemo, which he tolerated very well, and 6 rounds of radiation therapy. He has been on Lupron from the start and Zytiga for 6 years. He has side effects, but he has a great attitude and is grateful to be alive living a relatively normal life. His PSA has remained undetectable and no signs of the cancer except bones look the same on scans as they did from the beginning. Everyday is a blessing. His doctors attribute a lot of his success to his great outlook. I understand your frustration with lack of specifics (that's why I listed my son's Gleason score and detailed metastasis). Stories like this one are virtually meaningless without those details!

[@williamosorio1849]

Neem

[@Skwarek-wp8dc]

Need oil? How to use it?

[@patriciareynolds2729]

ED here, hang in there. know about the lupron, 1 dose, and i hate it.

[@rakeshgrover7435]

This is super helpful and full of vital information, coming from a person who has actually gone through all this and is so positive about the whole thing. In today's age, we have to be thankful to the internet and the loads of information available. Thanks sir!

[@MrJt3451]

thank you