5. Glycolysis Regulation : Explained Simply | Hexokinase, Phosphofructokinase (PFK), Pyruvate Kinase

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Awesome Biochemistry

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@ahsanishaq8714 Жыл бұрын

بہت شکریہ استاد محترم❤

@AwesomeBiochemistry Жыл бұрын

Thanks for the appreciation

@fidato795 Жыл бұрын

Awesome blossom as always🙏😊...Thankyou sir☺️

@AwesomeBiochemistry Жыл бұрын

Thanks for the appreciation

@positive5083 Жыл бұрын

Very helpful video sir👍👍

@AwesomeBiochemistry Жыл бұрын

Thank you for appreciation

@wittyetim6744 5 ай бұрын

That was splendid!

@Dr_SURAJ Жыл бұрын

Best video found on this topic

@DIPA212 10 ай бұрын

Very helpful class sir, thank you ☺️

@omegakachaka8801 5 ай бұрын

Hello sir, I'm a bit confused, i need some clearity, is it protein kinase that dephosphorylates the pfk2/ f2,6bisphosphotase. bifurcational enzyme?... By the way sir I love how you explained. You have gained yourself a subscriber

@fidato795 Жыл бұрын

Sir I've been reading somewhere that NAD+ also acts as the activator and NADH as inhibitor in the glycolysis pathway...Is it sir?

@AwesomeBiochemistry Жыл бұрын

Yes, But the role of NAD+ and NADH in the glycolysis pathway is slightly different from what you mentioned. NAD+ (nicotinamide adenine dinucleotide) and NADH (the reduced form of NAD+) play crucial roles as coenzymes in cellular redox reactions, including glycolysis. In glycolysis, NAD+ serves as an electron carrier and gets reduced to NADH during certain steps of the pathway. Specifically, in the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) reaction, NAD+ accepts electrons from glyceraldehyde-3-phosphate, leading to its reduction to NADH. This reaction is important because it generates high-energy electrons that are subsequently used in the electron transport chain to produce ATP through oxidative phosphorylation. NADH, in turn, acts as a coenzyme that carries these high-energy electrons to the electron transport chain, where they participate in ATP production. NADH is not considered an inhibitor in the glycolysis pathway but rather a product of the redox reactions that occur during glycolysis. It's worth noting that other regulatory molecules, such as ATP, ADP, and various enzymes, can modulate the glycolysis pathway by acting as activators or inhibitors at different steps. However, NAD+ and NADH primarily function as electron carriers and facilitators of redox reactions in glycolysis, rather than directly acting as activators or inhibitors. I hope this clarifies the roles of NAD+ and NADH in glycolysis. If you have any further questions, feel free to ask!