5-HTP dosage for depression | The RIGHT WAY to take this natural antidepressant supplement.

[@DrJanelleSinclair]

Have you ever tried 5HTP before? Was it helpful for you or did you experience side-effects? I'd love to hear about your experiences.

[@jon79jw61]

I have been usiing l-theanine for focus and energy can I combine the two for a better effect? Are they synergistic together.?

[@DrJanelleSinclair]

@@jon79jw61 there are mood supplements on the market that combine 5htp and l-theanine, usually for anxiety. I'm not sure that 5htp would be the best product for focus and energy. Maybe do some research into l-tyrosine. But we're all difference, so you could just start on a low dose and see how it affects you

[@alanpartridge8253]

great video, I just discovered 5htp and feel good effects for anxiety and depression, I turned to it because I had to wait 3 weeks to see my doctor to get back on citalopram, so I tried this in the mean time and am happy to stick with it instead of citalopram, I like that I can just buy it instead of having to go through the inadequate health system here in the UK. I've been on citalopram 3 times, and every time the doctor ended up weaning me off again because I felt normal again, but then a few months later I'd need to go back on it, and that on off process felt depressing in itself as a concept. Anyway my question is, in your opinion is 5htp generally suitable for long term use? Or do you think it will cause the brain to produce less serotonin at some point, or build a tolerance to it. Thanks.

[@alanpartridge8253]

@@DrJanelleSinclair Ah I've just seen that you've already answered that. "Unfortunately there's no long term studies on 5-HTP. It's shown to be safe in studies for 1 year." And someone else found it pooped out eventually for them. I guess it's a temporary solution and life improvements can be made with the extra boost it gives you.

[@DrJanelleSinclair]

@@alanpartridge8253 I think that you can work on resolving any deficiencies, support gut health and eat an anti-inflammatory diet while you are on the 5htp.

[@ViralWatchMedia]

For anyone coming across this video let me just say 5-HTP has changed my life for the better, I get an insane mood boost with it and I couldnt be happier with it. I take only 200MG a day once a day. I havent been this happy in years. I feel like the old me again. I can laugh again at the smallest things that would otherwise bore me. Its crazy!!!

[@DrJanelleSinclair]

That's wonderful Masta! Thanks for sharing. People need hope not just information. 👌❤

[@jeanmanzano9406]

Can it increase your appetite? Coz i don't have an appetite when stress..

[@DrJanelleSinclair]

@@jeanmanzano9406 not specifically. But if it improves your mood it may indirectly help you appetite. I'll link two other videos that might be relevant.

[@DrJanelleSinclair]

@@jeanmanzano9406 kzbin.info/www/bejne/eYDNeaCdftN8kJI

[@DrJanelleSinclair]

@@jeanmanzano9406 kzbin.info/www/bejne/p36YeYR5pdiJZrs

[@SEOshogun]

I started using 5 htp after seeing this video. I only later realized that I also have signs of a dopamine deficiency. I now take L tyrosine on an empty stomach in the morning and half the amount I used to take of 5 htp at lunch. This video changed my life and I'm so thankful

[@DrJanelleSinclair]

Awesome. So glad to hear that. I really appreciate your comment as it makes all my hard work worth it.

[@laurenkcolon]

How did you know you were deficient in dopamine? I am beginning to take the 5HTP now and I believe I may be deficient too, so I maybe need to have a similar routine.

[@JamesBrown-hs6vg]

Have you tried Mercuna puriens aka velvet bean. It’s better that L tyrosine. What are your symptoms of dopamine deficiency if you don’t mind me asking?

[@intermilan6202]

@@JamesBrown-hs6vg - I heard it’s really good… How much a you supposed to take on a daily basis??

[@HeartFeltGesture]

@@DrJanelleSinclair Some important points not mentioned in this presentation; Tryptophan is an amino acid, therefore it competes for absorption with other proteins. This is why it is advised to take on an empty stomach, and not at meal times! (you can also take with a small amount of carbohydrate, piece of apple, a cracker, to also aid absorption) It is also advisable only to take once a day in the evening when the natural serotonin / melatonin cycle is active. Also, it is very important to also take L-Tyrosine (amino acid) 500-1000mg (empty stomach) once daily in the morning for the length of time you supplement with 5-htp. Serotonin and Dopamine are on the same axis, that is, if you increase one, you force down the other, which can cause all sorts of unwanted effects and delay relief from depression.

[@Kazuelk]

I feel happy again like I did in my childhood.. thank you so much for changing my life! I was suffering for 18 years and now all is gone because 5htp and you saved me! 💕

[@DrJanelleSinclair]

Oh wow. I'm sooooo pleased to hear that!!!! Awesome. 💗

[@suzihazlove4979]

I'm glad for you

[@mayamorabito1669]

This gives me hope.

[@jamlano1]

What dosage did you take if you don't mind sharing. Thanks in advance.

[@Kazuelk]

@@jamlano1 I take 100 mg in the Morning and at lunchtime

[@ladydi7195]

TREMENDOUS!!!! It has made a tremendous difference in my life as I suffer from PMDD. I've been taking 100mg for a couple of months and noticed positive effects almost immediately; ESPECIALLY around my cycle time. After over 10 years now dealing with PMDD, I finally feel like my old self again. I am so thankful.

[@mrsconnors09]

Do you take of every day? I am stopping m 10mg Prozac in order to take 5htp the week after my period. That’s when my pmdd is the worst.

[@edibleapothecary]

I also take 5htp and have PMDD. I take 100mg once daily unless I’m very sad or weepy. I also take dlpa for the pain related to PMDD. I take 1500 mg in am and again afternoon. Start at 500 and work up.

[@hisnewlife3543]

I just started 5HTP. I am very glad to find your channel! I have suffered all of my life and now I am 48 years old and want to find relief from anxiety, depression and insomnia. I want to be able to live a normal and productive life.

[@n.s.5278]

Hi. How is it going for you?

[@Fantaszy]

Hope you’re doing better, any update?

[@sergiorobles7169]

take creatine and find out about agmatine

[@mackeyjaylozada2453]

Update

[@Prettysunshine982]

Update with how you're getting on ❤

[@Viv8ldi]

5htp good both for insomnia and depression Memo:3x50mg a day. If side effects, start with 50mg a day, if you notice nothing (within 2 weeks) increase to 100mg 3x a day, possible to incease up to 150mg 3x a day; Doses more than 200mg seem to increase anxiety 5-htp can help with weight management, makes you feel fuller

[@marydidyouknow5826]

5-htp is the only thing I've ever taken that I had a positive experience with (and I've tried quite a few medications and supplements), so it's surprising that it's taken me so long to look for information on it again. I'm just much of a pill taker, but after my mother's death, my depression has sunk to a new low. I'm going to try it again. Thank you for the information.

[@DrJanelleSinclair]

My pleasure Mary.

[@animalliberation9222]

I am sorry for your loss, I also lost my mom and my depression hit an all time high so I’m so desperate for help. Meds don’t work on me. If you see this as you wrote a year ago, can I ask if the 5htp helped you? I hope so.

[@SharlenesJourney]

Sorry I hope things are going better now

[@boushae6364]

This is irrelevant but I really like the way you speak it’s not patronising and soothing.

[@DrJanelleSinclair]

That's kind. Thank you. It might not be about the video, but it does encourage me to keep sharing my knowledge.

[@Tarmgrover]

ASMR

[@boushae6364]

Tontoturbocomputersociety I don’t like asmr I was just complimenting her voice.

[@ubelove4410]

@@boushae6364 this video is very helpful for people who dont want to take prescription antideps.

[@briseymone]

Thank you, this is great info and 5htp has changed my life in just 2 weeks of taking. I have struggled with depression since 18 as a result of hormonal birth control combined with family history. I wish more doctors in the U.S. had knowledge of naturopathic interventions. Instead, big pharma reigns supreme but 5htp is my go to.

[@sammyg.5403]

I’m taking 5htp for a week now and I do feel better. I believe you have to keep working on yourself to fight depression with 5htp. Good food, sleep and excersise.

[@DrJanelleSinclair]

Glad to hear that. This channel is all about working on the reasons for low serotonin and depression. Check out my other videos for more on this topic.

[@sammyg.5403]

Dr Janelle Sinclair I’m checking your other videos. Thanks for sharing all this information

[@DrJanelleSinclair]

@@sammyg.5403 my absolute pleasure

[@martinfrostevall7583]

For pmdd should you take it everyday or stop the time when symptoms usually go away? Asking for my partner

[@MrSwanseajames]

You look and come across a very caring and lovely lady. Thank you for your thoughts and help.

[@DrJanelleSinclair]

My pleasure James. 👍

[@kargas5490]

i've only taken 5htp twice, but both times i noticed i was genuinely happier for the entire day by 6x i noticed all my lethargy had gone and i was singing out songs in the car and laughing harder and louder at things that probably wernt that funny, i had 100mg and im extremely sensitive to medication and i noticed my body temp rise and heart palpitations and dilated pupils, but once i find the right dosage i can see this becoming a staple in my life

[@SharlenesJourney]

Are you still taking it ?

[@GrillaStyle]

I took one last night and woke up this morning feeling more clear headed.

[@explosivediarrhea4671]

What dosage

[@GrillaStyle]

@@explosivediarrhea4671 only one. But I kept taking them the next few days and felt good

[@letsgoalready5515]

I just bought L-Theanine and 5htp as alternatives for my sister if she runs out of her regular meds and needs something in the waiting process. She ended up getting her meds filled but since I also struggle with anxiety and depression too I decided to try 5 htp. I noticed I made me a lot calmer and even giggly at times from one 100 mg pill.

[@SpiritualThugLife]

Definitely going to try this! I talked to my therapist and she said a lot of her patients take this. Can’t wait I hope it helps me

[@erikaluna4336]

Did it work for you?

[@younesmks3111]

Please did it help you ??

[@Openup0911]

Took my first dose yesterday and normally at the store or out in public I’m constantly anxious thinking everybody is watching me (when I know they’re not). I went to the store yesterday and noticed when I got to the car I was absolutely unconcerned about anybody at all. I was able to stand in line and all that was on my mind was what I was going to do later for dinner when I’d normally be antsy to get the hell out of there. I also have insomnia and take 50 mg of Benadryl to get to sleep. I slept and only woke up twice when I usually wake up about once every hour and had a dream where I laughed myself awake. I haven’t had any dreams like that since I was a kid. I will definitely keep 5htp around.

[@christianfernandez4285]

Wow i used to be like that and because i didnt take anything im mich worse now cant go out of the house and im sacred to try medicine, i got prescribed escitalopram and alprazolam but i dont take neither How much and what brand did you use how are you now?

[@surfsuppel]

Did you take a dose before bed?

[@WierdGaming95]

YES - because 5htp transform to melathonin wich helps you fall asleep (:

[@Nightbird.]

Benadryl is awful long term. I had so many side effects from it (google it) and didn't even realize it was causing them. Switched over to timed release Melatonin from Sam's Club along with L Tryptophan. Great results with no side effects.

[@billwilliam4781]

There are so many 'doctors' on KZbin who do not tell you what their doctorate is in or what their experience is. This video is one of the rare exceptions. I trust the information in this video, plus the information is concise and clear. Thank you for posting this video, Dr Sinclair.

[@DrJanelleSinclair]

Thank you Bill. ❤ I work hard to be short and to the point, but accurate and complete in what I say. I appreciate the compliment.

[@saphire9823]

5htp helped my miragines go away. I was suffering for 20 years with them. i had tried everything before finding 5htp

[@josiespence3042]

I’ve been on Cymbalta for over 8 years and my anxiety has been getting worse the last couple. I started weaning off it very slowly one year ago, I’ve been down to approx 10 mg daily (had to break capsules open) yesterday I decided enough is enough. This morning I not taken Cymbalta and instead I have taken my first 100mg cap of 5-HTP. I’m going to try 100mg twice a day for a couple of weeks and see how I go. I’ve tried in the past to stop Cymbalta at this point without any thing else and after a few days I’ve gone back to it. But this time with 5-HTP and the support of family I hope I can be successful. I want my life back, Cymbalta has taken too many years and cause too much pain and sadness. Thank you for this video Dr Janelle 🙏🏻

[@DrJanelleSinclair]

How have you been going Josie? Has the 5HTP helped with reducing the cymbalta?

[@pauldumbraveanu9089]

Cymbalta lower with time serotonine !! Like any other ssri ! We must put the foundation( amino acids and cofactors to make serotonine ,not to manipulate the little we have in brain trick The brain to keep in synaptic more …… i Think this is not healthy on the long run !!!

[@Terri330]

I just ordered from Swanson, I hope it's good, I see all the positive comments , so encouraging

[@thencarolinaman1934]

Did the 5-HTP work for you?

[@Terri330]

@@thencarolinaman1934 It did not,

[@SharlenesJourney]

Any updates

[@taragunn9400]

Really appreciate the dosage advice. My instincts tell me to start lower than others as I am sensitive to meds/supplements, so it’s great to find that advice where many others don’t give it!

[@DrJanelleSinclair]

My pleasure. Glad it's helpful. Let me know how you respond to the 5htp.

[@grizzthegreen4500]

Yes, how was your experience?

[@taragunn9400]

I had a few days where I thought it was too much for me- got very (nicely) tired. But it evened out and I said goodbye to my Seasonal Affective Disorder ! I eased off it when spring came and will take it again next winter if need be.

[@desertboot9755]

@@taragunn9400 thanks for the update. Glad you're feeling better.

[@kiopos4764]

My dr. Recommended it years ago. I stayed on for a year or so then came off. I restarted it a few months ago and enjoy the way it stabilizes my mood, gives me energy, and helps with appetite suppressant. I would definitely recommend it and its best to pick the one for your body. Walgreens is where i purchase it from (nature made brand/100mg). No complaints so far😊.

[@DrJanelleSinclair]

Fantastic to hear that it works for you. 👍

[@EllieLewis-cj1sl]

​@@DrJanelleSinclair Can you take it for two years?

[@rebeccamisterly5332]

I know this is an older video but I'd love to comment! I started taking 5htp after starting a journey into psychedelics I read that a mental depression crash could happen from a loss of serotonin from the use of LSD or mushrooms. I started taking this about 2 months ago and it helped everything! I started dieting and excersizing around the the same time and ive lost 17 lbs and didn't know it helped with weight loss ..not sure about how it's working bc I'm really putting effort into this weight loss. This 5htp is awesome I'm able to be my self I don't over think anymore and everyone is noticing it . I have had some stomach upsets and I do take tramadol ..theres been vomiting a few times and then I felt fine.

[@carlosraygozaponce2393]

How are you feeling I now?

[@cocot9414]

Wow! I hope to have great results too.

[@mitrafereshteh]

Which brand is yours!?

[@d4rksydecaff]

Watch your serotonin levels when you're taking tramadol too.... Have you tried Kratom for your ailments instead of lots of medicines you just have to take a serving of this beautiful herb and your pains and low mood dissolve for 5hours at least 💚

[@heidih3048]

@@d4rksydecaff In my experience, Kratom does cause euphoria and increased alertness as well as helping with sleep. But in long-term use, it is addictive and if quit cold-turkey, it causes w/d consisting of serious increase in depression, short temper, and insomnia. I took it daily for 5 years, tried and failed to quit a few times, then finally stopped via a slow taper down to 1/4 tsp ground leaf daily. Despite the slow taper, I still ended up with ongoing insomnia issues ever since quitting (it's been 7 yrs now since I quit).

[@youknowcrimedontpay9257]

I have Fibromyalgia, I took it for nonrestorative sleep. I am medication resistant to SSRI medication and therefore I couldn't take any antidepressants. I had no idea that there is SSRI in 5HTP. It caused the same side effect as SSRI, tremors shaking and intolerable other terrible side effects. Many FM patients are medication resistant. Thank you for the video and efforts to help the people suffering. Giving you a thumbs up!

[@abutterfly7975]

I’m another one too.

[@youknowcrimedontpay9257]

@@abutterfly7975 I'm sorry to hear that. I wish you the very best.

[@yogeshsahu6895]

​@@youknowcrimedontpay9257how you doing ? I am starting 5htp wanna know your progress

[@blah-hg3cz]

Dr Sinclaire, I take 200mg (time release) in the morning on empty stomach but with other supplements. I was paralyzed by depression and anxiety but no more. If anything, I'm a bit too chill and calm. Also I find I only need to take it once per day. FYI I also take SAM-e 800 mg at the same time with no ill effects. I just wish I'd known about this earlier in life.

[@pauldumbraveanu9089]

I also have depression! What is good same for ?!

[@pauldumbraveanu9089]

SAM-e *** sorry !

[@yb6825]

I started taking five hydroxytryptophan when I was going through menopause I had anxiety ahead stress I had non sleep so I started taking at night to go to sleep and it works now I take 100 mg it's been many years now and I just passed the information to everybody

[@DrJanelleSinclair]

Thanks for sharing your experience. It's helpful for the community

[@reshmamohammed4525]

God bless you

[@ralfwashington1502]

I successfully treat my bipolar type 2 with 1 100mg capsule 1x a day on bad days. Exercising 2-3x a week greatly helped also! Don't just pop a pill get you self breaking a sweat it helps a lot too.

[@mohansinghrajput6112]

I am also suffering with bp2 from last 8 yrs ..but this year the depression phase is since last 8 months... I am unable to talk with people ..blunt emotions ..forcefully i try to talk not naturally ??why is it so ...i was also on fluoxetine 20 mg for 3 months but no change so i stop taking fluoxetine ......can 5 htp will work for me to create interest in living

[@ralfwashington1502]

@@mohansinghrajput6112 I am not a doctor and can't give you medical advice. (I could get in trouble if I tried since I'm not a doctor) for me though it helped alot. It makes everything feel okay and alright. I do get overly depressed and I don't get manic. So it keeps me stable. Working out though makes me feel happy. So together I'm less stressed and in a good mood. However I don't take 5htp for more than a month since that can me dangerous. Everyone's body is different what works for me might NOT work for you. What ever you do ask a doctor or at the very least do your research and start slow. Low does anything natural you try. Don't be taking prescription medication for your mood while trying anything natural. But do your research. I'm not a doctor

[@mohansinghrajput6112]

@@ralfwashington1502 ok

[@vanheemskerk1]

@@mohansinghrajput6112 Anti depressions and bp is a bad combination!

[@tomaskey6844]

Thank you for this information. I am going to take more of it spread out across the day and use it more consistently. The biggest thing I am doing is changing my diet and will consider reducing the dosage after I get more consistent with diet changes.

[@DrJanelleSinclair]

Great I hope it really helps you. If you are looking for even more improvements you might want to consider registering for my just released webinar course. It's called Real Relief- the natural approach to resolving depression and anxiety. I'll be talking about optimising your diet, supporting your gut, addressing (and testing for) nutritional deficiencies and balancing your hormones. Check it out at www.drjanellesinclair.com/ecourse

[@SEOshogun]

Tom, I found one that is time released at vitamin shoppe

[@Tluv_1955]

5HTP helped me a lot years ago when I had bad headaches and anxiety it’s a life saver for sure !!!

[@DrJanelleSinclair]

Thanks for sharing your experience. It really helps others ❤️

[@Apollon_Musaget]

@@DrJanelleSinclair Can you please tell me how long a person can take 5 HTP? is it harmful to the body if taken on an ongoing basis?

[@amazinggrace5503]

How much and when did you take it please ?

[@amazinggrace5503]

@@Apollon_Musaget I don't think enough research has been done on that yet ?

[@DrJanelleSinclair]

@@Apollon_Musaget I have a video on long-term 5htp use. Please just search 5htp long-term here in KZbin and you'll find it

[@karenlaws6757]

No meds have helped me much in 22 years and am so severely depressed and can't function I don't sleep definitely going to try this

[@DrJanelleSinclair]

If you need more help check out my webclass www.drjanellesinclair.com/webclass it'll give you heaps of information about how to naturally heal from depression

[@DannyWifi]

Great information. Thank you Dr for taking the time to help us all through this journey of great stress and depression. You’re saving lives.

[@DrJanelleSinclair]

Thank you ♥️ that's so kind of you to say. It is my hope and prayer that people's lives will be saved through this content.

[@DiMECallofDuty]

I just started it but am also on 25mg of setraline. I have noticed my mood is better and I am more calm. Taking 100 mg 2xs a day.

[@Sabrina-os6ui]

Thsnks for your love and shining. It gives me hope. I just started with 5 htp and other natural supplements

[@carljohnson2050]

And how did it go?

[@amend021]

Hi Dr. Janelle! I’m so happy to have found you! I appreciate you using your understanding of biochem to apply to health conditions!! I am studying to get my doctorate in nursing practice in psychiatric mental health and this is an invaluable resource that you a providing! As you know naturopathy isn’t typically taught in traditional western medicine models. You providing education backed with science on the effects of supplementation is a hard resource to find and you make it easier to digest by making videos available! I appreciate you and all your hard work and effort in this endeavor!

[@LaMenteOpen]

I'm curious about the connection between 5 htp and heart conditions? I can't find enough information on this. Also the connection between 5htp and EMS.

[@bryandaniel2856]

I have started taking 100 mg at bedtime to help with sleep and mild depression. I may take another dose during the day if needed. But so far I do notice an improved mood already.

[@85nickelos]

Been taking for a couple days. Researched that taking it with EGCG(green tea extract) helps with more utilization in the brain. Also, good idea to balance your dopamine too with something like mucuna(L Dopa).

[@georgesinclair5967]

Hey Janelle. Thanks for being there for us. You're amazing!

[@gailfisher7668]

And I have to say, Dr Janelle, you are pretty amazing. Thanks for all of the information you share.

[@kimpaynter]

I have taking one 100mg in the morning omg it’s my best friend !! My doc said 2 times a day haven’t had to I feel so so so good !!!! I did get some nausea but not bad

[@rabarber9610]

Answer to video title at 3:00

[@DrJanelleSinclair]

Yes but if you're on any medication please watch the whole video! And there's tips about how to avoid any too.

[@awreckingball]

Thanks. What a waste of time.

[@edenrosederonsard]

Thank you. You saved 9 minutes of my life!

[@monikamoon14]

Thank you amazing human being :)

[@ghost4342]

Thank you

[@FewPewPewRah]

I take 5-TP, DL Phenylalanine, Gaba, Ashwaganda, and L tyrosine. Wht a game changer! i feel like a normal human being again.

[@CodyBosch]

Thank you so much Dr. Sinclair! I’m very hopeful. I just took my first dose, and I’m very hopeful that it works. My St. John’s Wort stopped working, so I’ve been looking into other natural anti depressants, and think this is probably a good option for me. Thank you the information, and I hope you are well! Take care.

[@DrJanelleSinclair]

Thanks Cody. Let me know how it goes. There's lots of other options available.

[@CodyBosch]

Hi Dr. Sinclair! I’m on day 5 of 5htp now, and I noticed great improvement on day one and two, but then I crashed. I believe this was the honeymoon phase or a placebo effect. So, I’m not sure. Anyway, still awaiting real results, but I’m only on day 5, so I’m not giving up on 5htp yet. I guess I’m just a little impatient, as I hate feeling so depressed and unmotivated. I’m ready to feel like myself again! Thank you Dr. for so much useful information! I definitely intended on staying tuned to your channel for a long time! Thanks!

[@Latessa]

@@CodyBosch How was it after all my dear friend?

[@SEOshogun]

@@CodyBosch have you ever seen Dr Sinclair's video on 5 htp and L tyrosine? After watching it, I realized I had both low serotonin and low dopamine. I now take l tyrosine in the morning and 5 htp with lunch. Changed my life! Good luck

[@ilianiperez2398]

@@CodyBosch Hey how are you feeling??

[@gorillaboog]

Your video was incredibly helpful and exactly what I was looking for. It was clear, concise and even included information I didn’t know I needed. Your energy and aura is very warm and kind, thank you!

[@DrJanelleSinclair]

Thank you. ❤️ much appreciated

[@BerserkersBattle-816]

Back in my crazy 20s going to college we would hit the town and go to raves where ten thousand people would go every weekend and we dropped alot of ecstasy. Sometimes the next day or two would be rough until a friend told us about 5-HTP. That stuff would stop our hangovers and muscle cramps and made us feel normal the next day after a rave so it does work!

[@Swenthemen]

I'm in the same boat and also want to try it. Isn't it dangerous in the combination with ecstasy? And how much/when did you use it?

[@870Slager]

Yeah, or you could just, ya know, stop being a moron.

[@larrylucas5731]

You and my son suggested this supplement so I 'm going to give a try for my anxiety. I take pain meds for a back injury along with vitamins C, Omega3 and D3. If you read this and see a problem please let me know ASAP> Thank you for taking the time to make this video.

[@DrJanelleSinclair]

All of those nutrients can be taken alongside 5htp with no problem.

[@DrJanelleSinclair]

I used "low level laser therapy" (cold laser) for my daughter's long-term tailbone injury pain. After 6 treatments the pain was resolved.

[@larrylucas5731]

@@DrJanelleSinclair Thanks, can I take you to lunch? :)

[@Baddogbling321]

I have chronic stress and although this boosted my mood it also caused really bad insomnia. I would wake up after every hour and just feel wide awake with crazy heart palpitations.

[@blslalalalalalavandekunt7635]

5htp is crap, had the same. better take a long walk every day.

[@Mortthemoose]

That happened to me too. It was the main reason I gave it up, a few yrs ago.

[@KraftyUk]

I've just got nutravita 5htp for anxiety and depression, recently I was taking st John's wort in the mornings and valarian root extract in the evenings. I've decided to give 5htp a go, hoping for the additional benefit of a little fat loss.

[@Ej6daniel]

I'm 24 years old, i'm currently taking a SSRI and Gabapentin for Anxiety. I tried a sleep aid drink yesterday called neurosleep with 5-htp around 4pm and took two cat naps, from 430-6pm & 730-9pm. It really helped me catch up on my sleep! I'm going to talk to my doctor about possibly integrating it into my medications if it's safe. Thank you good video! 👌

[@pauldumbraveanu9089]

I take ssri and 5htp and no interaction

[@madebyut]

@@pauldumbraveanu9089 Please svoid taking SSRI and 5HTP together as this may lead to Serotonin Syndrome which can be fatal. Please take care.

[@DynastyInferno]

Have tried just about every type of antidepressant. They eventually stop being effective about 4 - 6 weeks in without a big increase and that brings more side effects, which ruin any positive effect the medication had. So frustrating and has left me feeling hopeless for years that I'd ever get better. I eat well, exercise and meditate already which makes my depression so much more difficult to kick. Hopefully a trial of 5-HTP will give me some life back, as some people have also reported my issue with antidepressants with 5-HTP being the overall solution.

[@SEOshogun]

Hi vexeri, check out Dr. Sinclair's video on 5 htp and L tyrosine. From it I realized I have low serotonin and low dopamine so anti-depressants alone didn't help. After adding L tyrosine I'm feeling much better

[@bobbymac1319]

Love your style of delivery, you are very sincere and caring, also very sympathetic and reassuring x

[@DrJanelleSinclair]

Thanks Bobby. Did you learn what you needed to?

[@bobbymac1319]

@@DrJanelleSinclair yes I did, because you explained it so well that it makes it easy for the average person to grasp👍👌

[@AnnahitaLessany]

Really appreciate how you took the time to clearly and effectively explain 5htp and the core things to know. Thank you and I’m subscribing now for further videos

[@AudioTruyenLangQue]

Thank you so much for your help and advice, I really appreciate your job. I wish you happiness and peace under the sky of prosperity. All the best. Take care and have a good time

[@victoriapadilla6806]

I just found my new favorite channel

[@DrJanelleSinclair]

If you like my channel then you're going to love my new online course. www.drjanellesinclair.com/ecourse. Let me know what you think Victoria.

[@Shrink18]

I just stopped taking 10mg Citalopram 2 weeks ago and I feel moderately depressed almost constantly right now. I’m going to start 5-htp and hopefully it helps lift up my moods.

[@DrJanelleSinclair]

Sounds like a good plan. Let me know how it goes for you. If you need further support for your healing you might want to check out my free webclass. It's jam packed with info on how to improve your mood naturally. www.drjanellesinclair.com/webclass

[@Shrink18]

@@DrJanelleSinclair I was diagnosed with PPD. My baby is 8 months old now and first I came off Zyprexa, then celexa, now tapering off of Clonazepam. I’m a lot better then I was but experiencing moderate depression and anxiety which is pretty crappy. I can’t tell if the 5-htp is working yet. It’s day 10 100mg 2X daily. Anyway yeah I’m wondering what to pair with it to possibly help me feel uplifted and less anxious without any uncomfortable side effects. I see reviews for St. John’s Wort and I feel like I might try it but would you recommend something else better then that or do you think it’s a good idea to go with that?

[@DrJanelleSinclair]

@@Shrink18 you should try omega 3 for PPD. If you would like a comprehensive approach that rules out vitamin and mineral deficiencies, then have a look at my online course: www.drjanellesinclair.com/ecourse or watch my webclass for more information www.drjanellesinclair.com/webclass

[@Shrink18]

@@DrJanelleSinclair I will get some better omega 3s as the Jamieson brand I’ve been taking is lacking in the proper fatty acids and the two tablets a day might not be doing much.

[@bigsteppa2200]

How are you now?

[@sheamessick9096]

This is great your doing amazing work.

[@DrJanelleSinclair]

Thank you!

[@lyudmiltsvetanov2385]

Thank you Dr. Janelle for sharing all this info with us. You help a lot of people.

[@decree4644]

I started taking max doses because i had my medication, methylphenidate 20mg x3 a day stolen. I understand that it barely works on serotonine, but this really helped some factors and i can sleep well for once

[@carriemcclure7253]

I am going to make sure I take this every day 🙂. I’m hoping to try it in the morning and in the evening to see how I do.

[@T-19-]

How did it go?

[@giovannicampos5838]

Hi DR Sinclair! hope you are going well. I am general practitioner and I've been reading a lot about 5 http and have a question. Is it possible to take the daily dose at once like antidepressants ? example for anxiety 100 or 200 mg/ day ? Considering to include 5 http as option for patients with very low income, who could afford a dosage of 100 - 200 mg daily. Thanks! Amazing video.

[@performancetravel75]

Thank you Dr I'm starting today Your the only one the breaks down the dosage GOD Blessed you

[@Viv8ldi]

Please Dr Sinclair can you do a video on the difference of Tryptophan and 5-HTP?

[@monicafitzgerald7027]

Isn’t that what it’s made of?

[@Youtubeinfluenza]

Doctor, warm hello from India. I consumed tryptophan in June, and noticed immediate improvement in my mood and fibromyalgia. Within two days, my brain was working the best it had worked in years. I was blown away!! Also my digestion the first few days was remarkable! However, by fourth day, I started feeling drowsy. And this was on just 500mg once a day dose of tryptophan. I eventually settled to taking tryptophan every alternate day and it worked well for me. I could never again feel the way I did on the second day after starting tryptophan - I was almost operating like Sherlock Holmes, no kidding! But anyway I was still content feeling the way I did. It was way better than how I was before tryptophan. Anyway, when that bottle finished towards September end, I got a new one but gradually I realised it didn't suit my stomach. It would trigger a bad case of IBS. I changed the brand, that also didn't help. I last week got 5htp, but its first two doses itself triggered the ibs again. How can I consume it without this IBS side effect. Would love some advice from you

[@DrJanelleSinclair]

Start on a small dose and increase it slowly. Also see my video about tyrosine and 5htp.

[@pauldumbraveanu9089]

Or take it sublingual form ! Less side effects !!!

[@marianad.4841]

5htp and pregnancy? I have severe depression and anxiety and even though doctors have tried putting me in all types of antidepressants, 5htp (200mg) was the only thing that works and with no side effects. I would like to get pregnant but I'm affraid the doctors will try and take me out of 5htp again and I will go back to feel miserable and with suicidal thoughts...I want to be pregnant and taking what makes me feel the best (which is 5htp)..

[@DrJanelleSinclair]

That's not an easy one Mariana. Unfortunately there are no studies on 5HTP's safety in pregnancy and breastfeeding, but there's no evidence that it causes problems either. Some people prefer to use it rather than antidepressant medications. It's about balancing the risks versus the benefits.

[@michaelallen1154]

Holy smoke! I can't believe i never subscribed! I remember you! Well, I'm subscribed now.

[@Thomas_loco_motive]

Thank you Dr......this is my third week with 5htp and it changed my life....i take 50mg 3 Times a day and my panic is gone.....i could cry for not suffering anymore...i cant fit it in words how thankful i am. Two more question can i take it like forever? Cause i dont really want to Quit...and are Passionflower and ashwagandha contra-indicated to 5htp because i also love the way the calm me down

[@mouwlylee5014]

Try to take one a day it still work. Buy 100 mg at Costco

[@rosy21284]

what brand of 5htp do you use

[@Thomas_loco_motive]

@@rosy21284 i'm using a high quality german brand called kurkraft.

[@santosturmio8189]

@@Thomas_loco_motive ja man bestes Zeug xD

[@Thomas_loco_motive]

@@santosturmio8189 echt so 😁

[@sirlaw2930]

I love this video and your approach. I'm going to watch your series.

[@zakariyyakhayyat]

Very rich and informative video,, many thanks doctor

[@DrJanelleSinclair]

My pleasure

[@simpleman2988]

Thank you very much for the reply, last question, can I use it with B vitamins and probiotics?

[@MrClimateCriminal]

What about tolerance, rebound and dependance? Are these issues present with 5HTP?

[@BrokennessAndBeauty]

I know I gain a tolerance to it.

[@charlypetra191]

You have very good information that should have the Best Audio, rooms often have reverberation off of hard walls that can be helped by hanging up foam or large tapestry, blankets or other such materials... the room should be "dead" to echo as you can make it...the floor also should have a rug, Ideally also the ceiling but 5 out of 6 flat surfaces will be fine. A I found the slightest reverb that you may not even notice made your accent harder for my ears and brain to absorb. Thank You.

[@DrJanelleSinclair]

Thanks for the tips Charly. I'm just new to this and trying to get the right equipment etc. I hope to improve it in the future

[@mikegr8972]

Hi Dr Janelle, I was scrolling through the comments but I couldn't find anyone asking about what happens if you stopped taking 5HTP after taking it for a while? Because I've heard with prescribed anti-depressants, if you plan on coming off them, you're not supposed to come off them suddenly, as it could greatly impact your mood, and you should very gradually come off them? Although, I haven't heard many cases in people coming off anti-depressants, but more like increasing their doses more and more...

[@carriemcclure7253]

I just found 5 htp....really helping me.

[@alexandraella3320]

I took 5-Htp to treat my long term very troubled sleeping pattern and it worked within few days. But after 5 weeks of taking this supplement I started experiencing a very low motivation ( have read that eventually an increase of HTP lowers dopamine levels). So I stopped taking it. Since then I stopped experiencing any sleeping issues , but I am in a very bad places depression and anxiety wise.

[@ralfwashington1502]

(If you healthy enough) try exercising an hour 3x a week. Like really break a sweat where you are temporarily out of breath. If you are healthy enough.....start with a stretch then go for a fast walk for 1min and then jog for 3-5 mins till you are tired or you are getting weak. Now your body is warmed up take a min break and do pushups and situps or other lifting things. End with a stretch and lots of water. Also get vitamin D blood work done. That effects the mood if it is low you will be depressed. Being a guy I take vitamin D supplements and try to hit the gym a few times a week and feel great. Oh if you started birth control I think that could make you depressed BUT I'm not sure. I'm just a dude on the internet NOT a doctor and NOT allowed to give medical advice. This is just what I've done and guesses

[@christianfernandez4285]

How are you now?

[@pavelkareski4505]

Maybe your depleeted ur dopamine Takeshi l tyrosine

[@AlbertaGengar]

Thanks for the heads up on not mixing 5HTP with SSRIs. I only use in summer so maybe next winter I'll try 5HTP instead. Ill be sure to check out your other videos

[@SaturnCrashing]

Just started taking L Glutamine. Can I take 5-HTP with that? Fantastic video btw.

[@DrJanelleSinclair]

There should be no problem taking the two together

[@joebmxx]

I had been suffering 6 months of random daily anxious physical symptoms since having a panick attack but without really feeling mentally anxious. Dizziness, Migraines, Weird vision, Headaches, Random body pains, Chest tightness, Neck ache, Pounding heartbeat, Heart Palpitations, Acid Reflux. All with no answer or solution. I started taking 50mg 5HTP a week ago and 90% of my symptoms have gone. My mind is actually blown, I feel like I'm dreaming.

[@DrJanelleSinclair]

So happy for you!!!!

[@MassimoG20]

Are you still taking it and how r u feeling?

[@Morrighanangel84]

She made me wait just to tell me I can't even take it

[@marieb.1810]

I am going to try this. I am older and going thro divorce. There is absolutely NOTHING that gives me joy or peace or contentment. I sit with my new friends and talk with them, but inside i am dead and i want to get up and run away, but i force myself to stay with my friends. They have no idea how i feel inside. I will give this a try and report back later.

[@elenakliuzhina8527]

Thank you for such an informative video! I’ve been taking 5htp for 3 months now and when I try to stop taking it my depression comes back. Is it safe to take 5htp for the rest of my life? I really don’t want to experience depression again, nor do I want to take strong antidepressants.

[@ralfwashington1502]

1st I'm not a doctor so this is NOT medical advice. From what I read you shouldn't take it for longer than 3 weeks or your body will notice the increased levels and slow down its natural production. So 3 weeks on 1 week off and repeat if necessary. From the limited research done they aren't sure long term effects but early tests show it might cause bone density issues with long term use. My doctor told me to wear a heavy backpack or a weighted vest (think weight room weighted vest) and walk around for a while each day to load up my bones and maintain it. He said you need the weight over your shoulders evenly so your skeletal structure all has a slight load on it then walk with good posture. I find excercise in general naturally lifts my mood and I rarely need my 5htp. I did a blood test and found my vitamin D level was extremely low so I take a supplement for that which also helps my mood. I try to cut out lots of carbs from my diet too since sugar (carbs turn into sugar in the body) naturally helps cancer grow and is as addictive as some illicit street drugs. Pretty much take 1 week off a month and break a good sweat working out jogging pushups ect (if your doctor says it's safe) and eat clean food going low carb but high healthy fats and proteins or keto diet. Get your 8-9hr of sleep and make sure you aren't deficient in vitamins especially vitamin D.

[@clintton888888]

I had poor sleep problem for many years and used to wakeup sleepy and headace and felling tire during day . I tried exercise , fasting, meditation +++ even sleeping pill and nothing work . Now I take 5htp 100mg every night and it helped me wakeup feeling good. morning i take 100 mg and feel calm for the day . Btw I also take B6 B9 and B12 together . One more thing I found 5htp will not help me getting to sleep and some time make me feel awake but taking it close to sleep will make the sleep very very very good sleep

[@tukm7226]

Dr Janelle, what’s the recommended dosage for an underweight 15 year old teenager who portrays depressive, anxious, poor sleep? She’s also low in iron and currently taking iron supplement. Thank you for your valuable info.

[@simpleman2988]

Hi doctor, is 5htp good for OCD? Thank you very much

[@DrJanelleSinclair]

It's worth trying. Also consider trying GABA.

[@markellis404]

Hi Janelle, great video! What would be your advice on dosage and timings when using 50mg 'prolonged release' 5-HTP, primarily for depression? Thanks in advance 👍🙂

[@eliettalcantara42]

Can you please make a video about depersonalization and derealisation and best remedies? Thank you! I love your videosb

[@nicensleazy1892]

interesting - good explanation. Thanks Janelle

[@DrJanelleSinclair]

My pleasure

[@SilentPresence]

I took HTP three nights; about 50 mg and got really bad headaches. Did not feel good the next day. Melatonin does same thing to me and makes me tired the next day, even 1mg. I think some people are just sensitive too these, not sure why? I have been taking Theanine for 2 nights and this might be more my thing. Relaxes me so I can sleep. I feel just a little relaxed with Theanine the next day but will cut dose in half and see if that helps.

[@DrJanelleSinclair]

Maybe try GABA for sleep. It's another alternative

[@VicSaidThat]

I take multivitamin liquid form, omega 3 plus vitamin d and drink golden milk at night...will they interfere with 5 htp?

[@DrJanelleSinclair]

No they shouldn't interfere with 5htp

[@peekaboots01]

What is golden milk?

[@VicSaidThat]

@@peekaboots01 it is turmeric mixed with preferred milk added to it coconut oil

[@danielventre5040]

Great video. Unfortunately, I should have waited until you got to side effects. I have gastritis and I'm withdrawing from alcohol, so my stomach is upset and I'm experiencing mild heart palpitations already. I also just popped a 100 milligrams of this stuff. That'll teach 'me' to take substances without listening to the directions all the way through!

[@morningofmagicians]

Hello doctor, your videos are so informative and helpful, so thank you!! My question is, is it safe to take St. John's wort and 5HTP (I have the 200mg once/day) at the same time? I've read they can lead to worsening of symptoms (I've been going through panic, anxiety, depression) but also that they are synergistic. What are your thoughts?

[@DrJanelleSinclair]

They work on the same pathways in the body so it's not normally recommended to take them together. If one doesn't work, try a higher dose (in the safe range) or look for something else to help that works in a different way. If you want to learn how I recommend people to improve their mood check out my free webclass www.drjanellesinclair.com/webclass

[@tutorialesguitarradelcielo9581]

Tyrosine and/or dl phenylanine and l tryptophan or 5htp seem to be working just fine for me. Be made well❤🌟

[@DrJanelleSinclair]

Fantastic! How long have you been using them?

[@tutorialesguitarradelcielo9581]

@@DrJanelleSinclairHello, I have been using 5htp and L tryptophan on and off for like a year. However up until recently i started taking dl phenylaline and tyrosine and i feel normal meaning not depressed or low self esteem. It definately did something that 5htp and tryptophan couldnt do alone. I also felt the change after a few minutes. Right now im just monitoring my self and trying to find the ideal dose for me. I have noticed l tyroaine makes me a little anxious but this definaltely is insignificant compared to the depressed life i used to have. But anything is manageable and now that i found these two new supplements i will get to the sweet spot.👍

[@kwesifrancis7652]

Could this work for dealing with the hurt from break up

[@dormbe4589]

The only negative side effect I have from 5-htp is nightmares / very vivid, intense dreams. Has anyone else experienced this on 5-htp? Any tips on avoiding or reducing these?

[@JonasAnandaKristiansson]

it is rather common

[@jacquelineitokinney4554]

Thanks for your work! Sam-e is another supplement used for depression. Is it safe to take with 5-htp or would it pose a similar risk to other antidepressants?

[@DrJanelleSinclair]

Hi Jacqueline. Yes SAMe is a very good supplement for depression and anxiety. I have never come across any expert suggesting that someone should combine the two. I would take either 5htp or SAMe. If you're finding that 5htp isn't enough on it's own, then you could consider 5htp and tyrosine together. I have a video on that.

[@cynthiahansen2341]

@@DrJanelleSinclair what do you advise for comt met/met? Can serotonin help modulate the overload of dopamine? I had crazy headaches with tyrosine. Estrogen.. lots of histamine issues. I eat lots of sulforaphane..

[@DrJanelleSinclair]

@@cynthiahansen2341 did you see my video on COMT?

[@cynthiahansen2341]

@@DrJanelleSinclair I did.. you were one of the first to address it. I will review. Are you still making videos? I went to your site, are you doing consults currently?

[@DrJanelleSinclair]

@@cynthiahansen2341 yes I'm offering consultations to both NZers and people internationally. www.drjanellesinclair.com/consulting I am changing directions at the moment with content creation. I'll be looking to start a podcast. Visit my website and sign up for my weekly newsletter to keep informed www.drjanellesinclair.com

[@wread1982]

Great video thank you 🙏 is Pure Encapsulations a good brand for 5htp?

[@Soaring_Seajay]

William Read I think so, that’s what I’m going to order.

[@priscillasekon7379]

Can you take 5HTP with Same e?

[@rebeccamuir3464]

Yes thankyou. Looking forward to mine arriving.

[@shaspell2881]

Would I be able to take this along side minocin? It’s the medication I take for acne

[@rickywise9614]

Just started taking it so good noticed a change

[@DrJanelleSinclair]

Awesome so glad to hear that!!!