L-Tyrosine and 5-HTP: Do you NEED to take them together?

[@DrJanelleSinclair]

Register your interest in my online course- Real Relief: The natural approach for resolving depression and anxiety. www.drjanellesinclair.com/ecourse

[@Calaman345]

This was 🔥... please continue to dive into neurochemicals more Dr. ❤👍🏼💯Appreciate your work

[@DrJanelleSinclair]

@@Calaman345 thanks Cal. Any particular topics you're interested in?

[@Calaman345]

@@DrJanelleSinclair Dopamine.. dosage, intake, studies on supplementation of precursors to dopamine.. Oxytocin...how to increase with supplementation, increase naturally. Pros and cons of having high or excess Honorable mention: Cortisol, NAD+

[@compostcorner5934]

Hi Janelle, I have just bought some L Tyrosine and 5htp.. My question is can I take these with Tramadol... Long story short. I'm trying to get off the tramadol as my back pain has fortunately now improved, the problem is I had become addicted to the tramadol, so Iv been having to take it, just to feel normal So my plan was to eventually get off the tramadol completely with the help of l tyrosine and 5htp. Thank you Tony

[@macIain]

Dr Janelle Sinclair, can we take these supplements continuously on a long term basis or should we just take them for a certain amount of time?

[@pskelton1000]

She begins to answer the question 3 minutes in...fast forward.

[@becomingfr33]

Thanks for giving me 3 mins of my life!

[@spiikedude]

You sir, are the hero we are all looking for

[@jmiogo]

Thank you

[@DonCannone]

I should have went to the comment section first. It was painful

[@avatar1867]

My hero

[@jmiogo]

3:12. She finally stops telling you what she’s going to tell you and tells you.

[@Ds4u2]

Gotta extend the video to 10 minutes to get dat youtube money baby

[@ionseven]

Thank you

[@DrJanelleSinclair]

@@Ds4u2 there's no ads on any of videos. I make no money off them

[@kylegraham9794]

@@DrJanelleSinclair do you take them at same time as each other or space out when you take the 2 supplements? Thank you.

[@mstenson4]

@@kylegraham9794 space them out like she said in the video. Tyrosine before breakfast/lunch lunch, 5HTP at dinner/bedtime

[@zianawind2970]

I really appreciate how thoroughly implemented delivered this information is. There are so many less informed not professional you tubers talking about nootropics and though it’s good to get the word out it’s nice to hear from someone that has more than 3 months experience! I’m definitely subscribing thank you for sharing information about this things in a trustworthy coherent way.

[@chlecziferryn2895]

It's probably good practice for psychiatrists to test their patients for low serotonin and dopamine levels and prescribe them nootropics(5htp, l tyrosine, l theanine, st johns wort, etc.) instead of man-made medicines that have really bad side-effects and withdrawals.

[@mansakonko7777]

The only medical professional who doesn't look at the organ they treat....apart from behaviours. Brain scans, blood work should be part and parcel of the psychiatry modality.

[@GemstoneDragonPrincess24]

Thank you for saying this. I am a college student who is currently on the path to getting a psychology degree and I plan to get another degree in Neuroscience as well. I love art and music therapy and want to be able to provide services for people who don't want to take prescriptions for whatever reason

[@robturnlund1529]

Interesting video, my husband was diagnosed 4 years ago with FTD and he has had insomnia chronically and foggy headedness during the daytime. I started him on 5htp and he has improved significantly with better sleep and increased energy and the brain dig has cleared completely! Interesting also his chronic sinusitis has resolved and he can smell again for the first time in decades. Don't know if it is curative but it sure has improved his quality of life!

[@DrJanelleSinclair]

Wow that's an amazing change with just 5htp.

[@keelyleilani1326]

I'm doing 5HTP and Tyrosine every night along with L-Theanine and some GABA lozenges too. These 4 really synergize quite well together. I've noticed much better sleep and a lot less depression and anxiety during the day as well.

[@DrJanelleSinclair]

Awesome. Glad to hear that. I usually recommend tyrosine in the morning to pick up mood and then 5htp at night for relaxation and sleep

[@MdShahin-nm7xw]

How many mg do you have taken sister? Pls update how it works for you

[@brucebanner912]

hello. How it works for you? How many mg of these drugs are you taking?

[@brucebanner912]

hey

[@husamalbayati4433]

I take L.Theanin 200 mg (one capsule) with 5HTP 100 mg (two capsules) every day.

[@missnerd4832]

Thanks for this! I stopped with my ADHD meds and am now taking tyrosine (650 mg), vitamin B complex and omega 3 in the morning and 5htp (100mg) at night. Perfect combo!

[@PM-tk3se]

Yay. Happy for you. Cool to hear that it works

[@tapatot541]

What’s the brands ?!

[@csgotunibetprediciton4019]

@@tapatot541 just make sure they dont add shit in the supps then you should be fine i guess..

[@safvanchenathsafvan980]

For what

[@marijazlatar5457]

You use too much.It must be 1:10. 5HTP in morning 50 mg and Tyrosine in evening 500 mg with other suplement b komplex cooper magnesium to better absorpcien.

[@idiotheh]

I take both and it's been a miracle. I tried every variety of antidepressant for years and they never improved anything.

[@케로로-중사]

can you tell me more details review? :)

[@csgotunibetprediciton4019]

Hey, in what dosage you took them?

[@dorislacej8717]

In what dosages?

[@manchester8143]

Wow thats great

[@trulydivin3]

Her Answer: 5-HTP is fine alone.

[@DrJanelleSinclair]

For some people, but not for others. 👍

[@deni32biberic9]

@@DrJanelleSinclair Hi Dr Janelle.sorry.Can I drink 5HTP and L Terosine together? Thanks

[@glaubermarcius]

Thank you! A prolix video, just to say a simple assertion. Bet she is not MD.

[@DrJanelleSinclair]

@@glaubermarcius no I'm not an MD and I tell everybody that. I've got a PhD in biochemistry.

[@DrJanelleSinclair]

@@deni32biberic9 yes you can

[@just_bee9482]

my brain needs both asap. I am doing well staying off pmo for a few months already after three decades of abuse but my brain has lot of repair to do.

[@Solami987]

Thank you for this info! The internet is overwhelmed with this idea of needing the two together. I personally think I need both, especially after trying L-tyrosine 1 week into starting 5htp. Your guideline recommendations are spot on. I made the mistake day 1 of trying L-tyrosine with 5htp at night and my sleep was not great, as you mentioned might happen.

[@Solami987]

@saidboulila4704 I used to take 5htp in the day, it negatively affected my sleep at night. Tyrosine early day, usually just 500mg once in the morning still, but sometimes a second dose early afternoon, but not too late. If I need a serotonin boost, I opt for less potent things than time release 5htp, but it's still good, I just had to rotate off it a lot. I prefer a very tiny dose of mushroom gummies instead (but that's not accessible for all ....). Usually I don't need the serotonin as much. Ashwagandha may help me in that respect. Either way it's nice being able to take any of these things when you feel a need, instead of being on prescription drugs. Assuming you don't need the stronger pharma stuff, I'm better without it

[@TheAngryZebra]

I prefer to go one step above and take tryptophan personally. Study symptoms individually and put it in one camp or the other. If you are serotonin deficient, then take either tryptophan or 5-htp. If you are dopamine deficient, take tyrosine. Don't take one JUST because you are taking the other. Treatment must be symptom based. That being said, one will brake and accelerate the other. You are aiming for a balance but you also need to be taking BOTH amino acids in through your diet anyway or in supplement form. You can't put one into the body and starve it of the other one. Keep in mind, tyrosine+iodine+selenium is needed for healthy thyroid function. Dopamine deficiency can make you tired but so can an underactive thyroid due to lack of tyrosine/iodine. If you are switched on enough, you can actually tell what chemical your brain is seeking. Also, beware of sugar foods. These provide a quick hit of brain chemicals so if you are constantly snacking on them. It can be a sign that you are completely amino acid starved. Throw that in with a bad thyroid and it's a recipe for huge weight gain. Don't forget, tyrosine in particular can affect heart health and blood pressure as well. If in doubt, take them individually, the uptake through your body might be so rapid due to being starved of an amino acid for so long you can experience all sorts of symptoms. In cases like these, take 10-20% of the recommended dose. If the effects then work out to be beneficial to you then just take as required. It's like swimming. You'll soon learn how to ride the waves.

[@DrJanelleSinclair]

Thanks Russell for your input. One should definitely concentrate on improving your diet first before taking supplements

[@ifonly2675]

As a dopamine deficient individual i supplement with L tyrosine or L phenylalanine. I only use small amounts of tryptophan from time time when i get sudden and unusual sugar cravings. This is the trigger that my serotonin levels are too low. However if i take 5 htp or tryptophan alone then my depression gets so much worse. It takes a lot of time and experimentation to know what works for you

[@tashalodge1340]

5 htp was awful for me when I took it before. That was without l tyrosine. I've worried a little that I'd deplete my serotonin taking the l tyrosine alone... I guess I can do similar if i start to see symptoms of seratonin deficiency. It's interesting.

[@Thomas-pq4ys]

I just saw a video on being serotonin dominant... and believe I fit the bill. I also suspect, I'm dopamine deficient... I'm ADHD. Adderall was overkill, and quickly became inefficient, destructive to the clarity of thinking. At one time I took an SSRI for depression, and it made everything worse... extremely so... intense adhedonia, no joy, even at things that gave me joy in the past. In my youth, drugs and alcohol did a wonderful thing to lift my mood, increase motivation, and even helping this ADHD guy focus, intensely. I'd rather not get my dopamine from drugs and alcohol.... I need to find a less harmful and healthy way to do so. I will give L-Tyrosine a shot. Thank you.

[@gotzz84]

So how did it go with l-tyrosine?

[@emankcineht497]

Such a clear but also detailed explanation, just what I was looking for. Thank you, you doing really good job here!

[@FromDeath2Life4U]

This doctor is smart as she is pretty... And she's very pretty! Thanks for this information

[@DrJanelleSinclair]

Thanks so much 🤣☺️

[@DrJanelleSinclair]

@Wilfy Martinez sorry I missed your question. Yes that ratio should be fine

[@markspurgeon5646]

AM: Ashwagandha + ZMA + L-Tyrosine PM: 5-htp + CBD

[@ashleywyatt7114]

What is zma? And what brand of cbd would you recommend? Also what brand ashwagandha?

[@kritsaphongphuthibpaphaisi1509]

@@ashleywyatt7114 ZMA = Zinc + Magnesium + Vitamin B6 (P5P)

[@gailhowes9398]

I have Parkinson’s disease plus MSA for 22 plus years,so I am very pleased by your videos and I have every symptom you listed! So I have changed my supplements that will help me from what you suggested. Thank you so much!

[@Ayrad160]

I hope you are doing better.

[@littlelulu4107]

Have your symptoms improved?

[@pratiknaikedu]

Thank you SO MUCH for this! It's been really helpful! Please keep producing great content you are easy to listen to!

[@LoriBradshaw]

I definitely lean towards a Dopamine deficiency Depression Fatigue Inability to feel pleasure Poor Motivation Poor Concentration

[@death.for.breakfast]

Same

[@IISuperw]

Same here. No.motivation in life to do anything Even if i think about doing my job, that would trigger my anxiety. Any idea how to feel motivated and anxiety free ?

[@twoibrad3688]

@Anmo yes, take 1g of Omega 3 EPA daily, also highly bioavailable Vitamin D3 (best with K2 MK7) and magnesium glycinate. I've tried and researched a lot and these are my big three. Exercise is hella important too though. This 4 things will make you feel satisfied nearly all day and night long

[@manchester8143]

​@@IISuperw same here

[@IISuperw]

@@twoibrad3688 true. I tried vit D. It did make a difference. But takes time. It took me a year to feel better

[@outdooravenues5373]

Thank you for the excellent explanations of how these supplements get converted into neurotransmitters and how and when to combine them. I'm recovering from Long Covid and have been struggling with PTSD, depression and anhedonia. I've tried 5HTP on it's own and plan to try adding l-tyrosine.

[@brisha.j]

Oh my god finally I just found this video I been so curious and I was just launching around on here so I’m happy I found this thank you for coming out and talking about it doctor

[@paolosoriani2106]

Finally a comprehensive and clear explanation, thank you!

[@bblack.orchidd]

I've been taking 5 htp and it works wonders for me in terms of my mood but not my energy levels. I do struggle with very low fatigue and depression. I took my first dose of L-tyrosine yesterday and the migraine that followed is so bad that I can't take it again. I still have a migraine today

[@LillyOfTheValley77]

How many mg of tyrosine did you take? I have heard of this side effect more than once sadly

[@binathere2574]

I have understood that when Tyrosine give a headache it usually means you already have adequate Tyrosine.

[@kangaroobrisket6118]

Thank you for this information!!!! I have been taking both. Now I'm going to just try 5-HTP. I'm hoping I could cut out the Tyrosine. Thanks again Doctor. You are smart and pretty.

[@DrJanelleSinclair]

Thanks I'm glad it was helpful. If you need any further help with depression or anxiety check out my online course Real Relief Foundations. www.drjanellesinclair.com/ecourse. It provides a comprehensive natural approach to improving mental health

[@manchester8143]

This video worth to watch. Thanks doc

[@imcrazyo]

this channel is awesome. thanks so much for the thoughtful information

[@paulflint6254]

Thanks for the video, i definitely have serotonin deficiency. Anxiety and anhodenia

[@behindyou3689]

Have you gotten any better in 8 months?

[@paulflint6254]

@@behindyou3689 on new tablets so anxious less. Lamotrigine

[@munirobeidat7433]

These videos are very helpful, please continue posting please

[@DrJanelleSinclair]

Thanks Munir. I'm back to posting weekly now after a break. Glad they are helpful for you

[@jbuddyman]

Thanks for the info. I've been supplementing with both l tyrosine and 5htp for a few months. I must say, it has to be the combo as there is no way one supplement would do this. But it really does make sense. I have learned about catacholamines and l tyrosine will convert to all 3 catacholamines ( dopamine, epinephrine and norepinephrine) by addd. And 5 htp to l tryptophan or serotonin. I may suggest adding l glutamine to keep glutamate ratios up with the rest of the neurotransmitters and b vitamins which are good for the acetylcholine neurotransmitter. Long story short, stacking these supplements at the right ratio will give ultimate balance

[@jbuddyman]

Oh and don't forget l theanine for GABA. Taking gaba on it's own is not useful since it can't cross the blood brain barrier. In short 200mg 5 htp ( extended release recommended if you can find it ) 200mg l theanine 1g l tyrosine 1000mg or more of all b vitamins 500mg l glutamine This stack I rely for neurotransmitter balance and I've never had a problem taking this everyday but that's me.

[@rayanemartins544]

How much you take 5htp and tyrosine?

[@XAE_A_Xii]

is it possible to identify if a person is deficient in either serotonin or dopamine or both? if the answer is correct, then doctors should always run such tests before subscribing antidepressants. but i assume, that's not in the interests of big pharma.

[@aliveandwell3958]

Same question I have.

[@XAE_A_Xii]

@@aliveandwell3958 exactly, why prescribe serotonin when you have no issues with it. and when you start replacing what your body already produces in sufficient amounts, you just harm yourself in the long run.

[@aliveandwell3958]

@@XAE_A_Xii RIGHT!!! This is why I'm hesitant on using meds again. Most of them never worked for me. I will say, last year I was taking prozac and buspar for about a month and the reaults were pleasant, but still. I want to know EXACTLY which chemicals are imbalanced so that I can address them. I don't like playing these guessing games. I've spent much time and money trying to resolve my health challenges. One thing I do know for certain, my vitamin d is slow. I'm glad I at least know that much.

[@DJRenee]

Yes they can test for both. They cost a lot.

[@dprice81]

@@aliveandwell3958 if u test low on vitamin d, magnesium is what your body needs to absorb the sunlight properly

[@HaradaVar]

I'm sorry what is 1:10 ratio? I couldn't understand that part. Like the dosage of L Tyrosine should be 10x higher than 5 HTP? Can someone please clarify?

[@nanaalr4108]

can you give us a summary ?

[@evandugas7888]

I recently learned the new topic people have real research...

[@dr.ngoziibe3583]

You are helping lives. Thank you.

[@DrJanelleSinclair]

Thanks Dr Ngozi for the encouragement. It means a lot

[@georgewashington3555]

10:21 minutes. taking it together

[@rosethorns1893]

This is the first I’ve heard of this. I take 5HTP at night and I take L tyrosine in the day with Theanine.

[@luiggyorlandi]

I plan to do the same, how has that combination worked for you? I currently take 200mg L-theanine and 200mg at night but I plan to add 5-htp and L-thirosine as well as the doctor says

[@rosethorns1893]

@@luiggyorlandi I had to back off from the tyrosine. It was making me a bit jittery. I probably need to take less.

[@luiggyorlandi]

@@rosethorns1893 wow and it is precisely what we do not want to happen, yesterday and today I woke up nervous and wanting to cry for all that, the doctira says that taking only 5htp is not bad, but what about dopamine?

[@rosethorns1893]

@@luiggyorlandi right!? That’s exactly what I’m trying to figure out myself. It seems my dopamine receptors may be low. I’ve been trying to research how to increase the numbers. My mind is so messed up, I can’t remember what I’ve found out about that but ironically, they say to get better sleep…lol…limit coffee intake, internet, go for walks instead… I don’t remember everything but am trying to do what I can.

[@sharadeniese8703]

Thanks Dr. Janelle I managed to come out of antidepressant with your help. Its been a week without Cymbalta. I have been taking 5HTP 50mg 3 times a day but i still feel confused cannot remember things much so i will add tyrosine from tomorrow onwards. I also have been taking L theanine 500mg twice a day morning and evening. I wonder if its necessary to have them both. Appreciate your help dr. i am a single mum and have struggled 17 yrs with antidepressants i want to look after my daughter who is 16 now. May god bless you.

[@keelyleilani1326]

I had the same issue with the 5htp and I started taking only one dose right before bed along with Tyrosine, L-Theanine, and GABA.

[@ozguratakul3066]

Hi, what's your current status?are you off the antidepressant? I hope you made it. :))

[@villagegreenapothecary9946]

Great video with a lot of good information. Thanks for sharing!

[@ApolloBlueLIne]

I had wonderful success for about 6 months with 5htp at around 150mg a day. I then started having numb hands, neurological issues and felt very unhappy. I believe it was depleting my dopamine levels as it is slowly improving. I am finding it very hard to balance these isolated nutrients. You can find them balanced in foods, almost like that was where we were intended to get them.

[@tapatot541]

Do you take it with tyrosine ?!

[@jorgeluisrodrigues1322]

It's worth a try.

[@TheAlibabatree]

5htp worked ridiculously well for me (like, unbelievable) for about 4 weeks, then i noticed some side effects, and stopped using it. Im about to order some Tyrosine now, and I’m gonna try it again (its been a few months) both together. I know these supplements are not supposed to be used indefinitely, but if i can get even 6 months to a year, that might make all the difference.

[@Maksym307]

what dosage did you take?​@@TheAlibabatree

[@OyaRevolutionary]

Thank you for your help and time committed to helping 😊

[@mcelroyj2758]

Thank you for the information, Dr. Sinclair! Wonderful videos!

[@jaredking2473]

Love this. You really answered all the questions

[@DrJanelleSinclair]

Fantastic!!!! If you need more answers about how to heal depression then check out my free webclass www.drjanellesinclair.com/webclass

[@JD-wx3pk]

Great video and invaluable knowledge. Thankyou

[@ekat6025]

I tried separately htp and tyrosine and didn’t have much results. I didn’t know this informs, just intuitively bought htp, tyrosine and velvet beans ( macuna prurience). After two weeks I felt completely different.

[@daniellefudgell6359]

For depression what dose do you recommend for each and when do you recommend to take them

[@gambit3950]

I think I need both, thanks!

[@Calaman345]

🔴Just took 500mg tyrosine + 100mg 5htp on an empty stomach... 🔵its 8am & I'll be fasting until 12pm.. let's see how this goes

[@DrJanelleSinclair]

So how did it go?

[@DrJanelleSinclair]

A standard ratio of tyrosine to tryptophan is 10:1. You may want to trial less 5htp or more tyrosine together in the future

[@joaosilva-ji1ve]

@@DrJanelleSinclair 500mg tyrosine Morning 5g tryptophan Night ( I dont understand why talk about 5-htp if tryptophan is super cheap and gives the same? or its better to take 5-htp?)

[@Calaman345]

@@DrJanelleSinclair Went GREAT... I felt smooth, happy and productive. Just took the combo again TODAY.

[@FrozenKingdom34]

Got all shaky and anxious after taking 5-htp long term. Had no idea.

[@DJRenee]

How much were taking?

[@reneehaber2066]

Excellent explanations! Thank you!

[@stevendriskell]

Thank you. I needed to know how to balance them properly.

[@sacredholly]

Thank you! This was really helpful. :)

[@Ahmad-yi8yl]

Thank you Dr. Janelle Sinclair!

[@DrJanelleSinclair]

My pleasure 👍

[@madlenj.4644]

@@DrJanelleSinclair i feel depressed, have 0 motivation and everyting feels exhausting. But if i take 5HTp i feel calm but not wanting to do anything (its exactly the same state when you lay tired in bed and will fall asleep in some minutes). If i take L-tyrosine i either feel nothing or i feel fatigued. Whys that and what could i do or take?

[@DrJanelleSinclair]

@@madlenj.4644 I just you look into other causes of depression other than serotonin and dopamine imbalances. I have a free online course that goes through diet, gut health and nutritional deficiencies. Definitely get all the blood tests recommended and rule out deficiencies. So many deficiencies can cause depression and fatigue. www.drjanellesinclair.com/ecourse

[@Schreibtisch1]

Video starts at 3:13

[@youmuqututube4248]

Thank you ❤️❤️❤️

[@redsox7897]

Hi Doctor, is 5HTP superior to L-Tryptophan?

[@Sunny-bychoice]

In another comment she said she thinks 5htp is better because it is already partially converted and people have a problem converting from l-tryptophan to 5htp.

[@zuppagraves2945]

I take 5-HTP during the winter for depression and it works; however, it causes me to experience bad dreams every night that are very vivid. I hate going to bed at night because of this. Also, I take Levothyroxine which interacts with L-tyrosine possibly lowering dopamine production do not take L-tyrosine. There very little research on supplements, except for small studies, making it difficult to get an scientific information. Does anyone else experience unpleasant dreams?

[@TonyG-iu4td]

Me too. Been having the most horrific dreams since starting the combination 3 weeks ago. These dreams make your worst horror film look like kids play!

[@mercygrace.]

Not horrific BUT very vivid and "intense".

[@manchester8143]

Me having a good dreams

[@mr.anindyabanerjee9905]

Very well explained 👍

[@hamedm9330]

Thanks...

[@kareemahmed7028]

Thank you Doctor, I have a question please. Can I take Macuna to increase my Dopamine levels instead of Tyrosine..

[@DrJanelleSinclair]

Yes that's another option

[@DrRaisAhmad-nh5im]

I appreciate your wisdom for con commitent use of both l tyrosine and 5htp.but if I want to take l phenylalanine and l tyrosine what should you give me the opinion.

[@dubepat5732]

Omega 3, vitamine d3 and 5htp is good combinaison for anxiety and dépression ?

[@jessicayms2135]

Thank u for a comprehensive video Dr Janelle, appreciate yr work😊 Currently i am taking Ashwagandha for anxiety and L-Glutamine for stomach lining. Is it ok to take them with 5-HTP and L-Tyrosine ?

[@DrJanelleSinclair]

No problem. Just take the tyrosine on an empty stomach.

[@jessicayms2135]

@@DrJanelleSinclairThank u Dr Janelle.. I m taking 5-HTP with L- Tyrosine 3 days already as per dosage recommended in yr video.. I feel sleepy during the day.. Is it normal ?

[@manchester8143]

​@@jessicayms2135 yes thats normal

[@giovannicampos5838]

Dr if the patient has anxiety and fatigue but very mild symptoms, only can take the supplements when is at home is ok to have only 1 dose of each supplement. Tyrosine 500 mg before breakfast, and 5 http 100 mg night time? thanks amazing explanations!

[@aquarius113]

Hi can i take 5htp with melatonin for sleep issue?

[@TianaNashae]

Yeah

[@TianaNashae]

I’ll refer you to where i got mine online

[@TianaNashae]

drgavin_trips

[@TianaNashae]

On instagram

[@Paul-hu1ht]

You need to look at the synthesis of these neurotransmitters. I have homozygous variant TPH2 which means my serotonin production is very low, but my TH gene is very fast. Taking 5htp here shouldn't need a boost of dopamine too, however, my DBH gene is also screwed which means my dopa to norep conversion is heavily impaired. I dont think taking more dopa is the answer here, as I also have fast MAOB, but perhaps a dopamine/norepinephrine reuptake inhibitor would be better?

[@VijayRobertmodlr]

This is what i am looking for,Thank you very much....

[@DrJanelleSinclair]

My pleasure ♥️

[@DrJanelleSinclair]

@Wilfy Martinez the 10:1 ratio is just a starting guide. If you need more dopamine and feel better on higher levels of tyrosine then the ratio of 675:50 should be fine.

[@gbdguy445]

what is the name of the urine test you mention in this video. What labs offer it?

[@YourNay]

I have ALL of these symptoms due to high levels of anxiety and stress but serotonin levels are great where my dopamine is

[@Shrink18]

I’ve been taking 200mg 5-htp for three weeks now. I can’t tell if it’s making a difference. I started taking 500mg l-tyrosine as well two days ago. I don’t notice any difference yet. Still feeling depression and anxiety symptoms

[@DrJanelleSinclair]

Sorry to hear that Rachel. I have a live online training starting in 90 minutes time on how to resolve depression and anxiety naturally. Check it out at www.drjanellesinclair.com/webinar_aug2021 I'll be sharing lot's of really helpful info, and I'd love to connect with you there

[@jcbanbury]

Well clearly time to try something else right? It's all about experimentation

[@mikeg.3480]

Great information! Thanks!

[@winterpaws01]

How would these two play togethor with SAM-e? Is there any reasons not to use all 3 (SAM-e for liver issues). Thank you, fantastic video

[@JennellBarrett]

What would you recommend for overstimulation & anxiety ?

[@DrJanelleSinclair]

Hi Miss Jennell. I'm going to be selling an online on natural approaches for depression and anxiety within the next month. It may be very helpful for you as it talks about diet, supplements and testing. register at www.drjanellesinclair.com/ecourse if you're interested

[@ramonmartins163]

Personally I would reccommend 3-5 drops of 20% CBD oil in the morning and in the evening. It really helped me. I use a full spectrum oil.

[@JennellBarrett]

@@ramonmartins163 which brand do you use? ive tried several and they didnt do anything.

[@death.for.breakfast]

@@JennellBarrett l-theanine might be good. Take it with your coffee/caffeine

[@JennellBarrett]

B I’ve taken that couple times, different brands. It’s okay but not enough. I also cut out caffeine. Haven’t had that in almost 2 yrs

[@computeck9984]

Thank you so much for sharing your knowledge ! My therapist recommended GABA to treat my anxiety and depression, what's your thoughts on GABA ?

[@matthewirvin6505]

they say it helps calm your gut mood than your brain because it doesn't cross the BBB

[@teuvner]

Could I take it when I'm taking vitamin D?

[@DrJanelleSinclair]

Yes no problem at all.

[@jaclynrawls8573]

Thanks so much for this video! Question: why does everywhere I look on the internet say to take L-Tyrosine for up to 3 months. Does this have something to do with how long it was studied? Can I take it longer?

[@Soaring_Seajay]

Jaclyn Rawls Wondering as well.

[@zianawind2970]

I just get that is meant to be cycled to allow the body to readjust it’s chemical flows, like stop 2 3 weeks see how you doing before restarting. I don’t have the exact science for that but the body does better letting it have a rest cycle from the feedback it’s required from taking the supplement

[@fabianogiglio5170]

Great information. Thank you doc. I love your accent by the way :)

[@saidelhindawidelgado93]

Thank you for amazing info Dr. my question is simple, If the supplement is helping and you figure out your dose range, for how long is safe to continue taking it and also there are any sort of withdrawal symptoms after severing its use. Thank again for your support

[@memati7199]

Dr Sinclair 🖐🏻🤓 can i combine both L-Tyrosine and DHEA , for fatigue and mood ? Wish you a lovely day and thank you for your efforts 🌷

[@SurgeCess]

I just found a supplement that has both 200mg of 5-htp and 250mg of L-Tyrosine together. I just ordered it.

[@DrJanelleSinclair]

That's a lot of 5htp compared to tyrosine. Should normally be approx 1:10. I.e. 25mg 5htp to 250mg tyrosine.

[@SurgeCess]

@@DrJanelleSinclair oh wow, ok I will be careful with it.

[@Offroadjeepin4x4]

Would GABA be a good (and safe) addition to this regiment for depression anxiety?

[@DrJanelleSinclair]

You could trial it for sure. If you're interested in more options for anxiety check out my free online course. It teaches you about diet, gut health, blood testing and nutritional deficiencies for resolving depression. www.drjanellesinclair.com/ecourse

[@CambodianAmerican]

How about taking l-tyrosine and l-tryptophan together on the same day and how much dosage each?

[@jefffisher1045]

What kind of doctor should I see to check my levels that you talk about here and give advice on these supplements.

[@bamptonbred]

What are your thoughts on timed release 5htp?

[@brucebanner912]

Is it okay to take tryptophan, 5-htp and tyrosine together? how much should I take as a dosage? Thank you.

[@alondraacosta-mora6504]

yes please reply this question

[@brucebanner912]

@@alondraacosta-mora6504 If you are using 5 htp you have to use tyrosine. Because 5 htp increases the serotonin hormone, which causes the dopamine hormone to fall. To balance, you need to take tyrosine supplements, which increase the dopamine hormone. this should be 1/10. So if you are getting 100 mg of 5 htp, you should take 1 gram of tyrosine. some people says that using 5 htp is not healthy in the long run. Tryptophan also increases serotonin like 5 htp. So it is unnecessary to use tryptophan and 5 htp together. I don't know about tryptophan dosage.

[@rosy21284]

What are some good brands that are any one with good results can possibly recommend. Thanks

[@Sahibamokha6303]

Can you take 5HTP with Ashwagandha or Gingko Biloba? Please let me know!

[@MegaErnieMAN]

I can't sleep 7 hours straight :( I have add when I don't sleep correctly

[@stevejeansimon6098]

How do I find out if I am deficient in anything? I know that vitamin D is not one of them. But am not sure about minerals and other thing you speak about in the 5htp video.

[@dinta8692]

Thank you Doctor! great work! tell me if these 2 drugs can be taken by a person suffering from hypertension and he has high cholesterol, he drinks satins. Or is there an alternative to l-tyrrosine if it raises blood pressure? maybe add a motherwort?

[@manchester8143]

Yes you can

[@SRMannion92]

This is an old video. But I have taken these for about 6 months now. Life changing for mood/ anxiety/ concentration. Since taking I have noticed itching in random places in the body. Have no idea what is causing it, not rash etc. I TAKE antihistamines every day because of it. Sometimes doesn’t help. Could it be related to the medication of 5htp/ l tyrosine? It feels neuropathic. Drs not sure what it is

[@marnykhalil8845]

Thank you for this very informative video I have one question You mentioned not to take l-tyrosine if a person is diagnosed with bipolar disorder Can you elaborate on the reasons why not? And what to do in case of a bipolar disorder diagnosis in terms of taking 5htp and l-tyrosine supplements? Thank you

[@DrJanelleSinclair]

Hi Marny. One of the possible causes of bipolar disorder is high dopamine levels. Tyrosine increases dopamine, so you should not take it if you have bipolar. I would look into zinc deficiency, vitamin d deficiency, progesterone deficiency and mthfr genetic weaknesses. I've got videos on all of those imbalances and you can treat the deficiency and this may help bipolar.

[@nick2128]

@Wilfy Martinez how many times are you going to ask that

[@wread1982]

Great video thank you 🙏 😊

[@mohansinghrajput1504]

Do we have any video on mood swings or bipolar

[@mianshahmirali1607]

Thanks for the amazing video. Could you please let me know if Goat or Bovine Colostrum is safe for human consumption? I've come across a few videos in which Doctors claim that it contains growth factors that are not found in humans, thus it causes an immune response and might cause Prostate cancer in worst cases.

[@stormer6364]

How effective are Ndri antidepressants such as Bupropion increasing dopamine levels?

[@margieireland4934]

How about taking both of these with HRT medication?

[@pauldurus4783]

Thank you for all this good info. Does anyone knows where to buy this products from in order to have a good quality. The market is full of brands and makes it difficult to pick the right one. Thank you.

[@brettcoyle2399]

Guess I also need a serotonin vitamin to raise it