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During this webinar session, we zoomed in on the use of Planarians as an alternative in vivo model to assess developmental, neuro- and genotoxicity. The speakers discussed the added value of planarians within the 3R principle, specifically within the field of in vivo toxicity assessments, with a focus on developmental toxicity, neurotoxicity and genotoxicity.
Dr. Karolien Bijnens is a junior post-doctoral researcher in the Toxicology group (BiTE Lab, Hasselt University). Her expertise is centered on understanding physiological responses to toxicological stressors, particularly related to (neuro)development and redox biology. Over the past two years, she has put her focus on micro and nanoparticle-induced (neuro)developmental toxicity. To study the associated complex toxicological endpoints, she uses the highly regenerative planarian Schmidtea mediterranea as an alternative in vivo model.
Martijn Heleven, a PhD student in the BiTE lab research group at Hasselt University, has a passion for microscopy and is dedicated to advancing regeneration studies through the application of cutting-edge imaging techniques. His primary focus lies in combining conventional imaging techniques with real-time imaging to study the role of redox and neuronal dynamics in vivo, which is of significant value for assessing neuronal and developmental toxicity, especially within the context of ecotoxicology. He is also committed to enhancing effective communication within academia and beyond, advocating for accessible scientific knowledge across diverse audiences.
The RE-Place educational Webinars are organized to promote the use and development of New Approach Methodologies in Belgium by putting the existing expertise in the spotlight! The Webinars are open to all interested parties including scientists, regulators, the authorities and the public.
Participation is free of charge, but registration is mandatory.
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