A Glove To Treat Parkinson’s Disease?

At the July 13, 2022 virtual "Palo Alto" Parkinson's support group meeting, the speaker provided an overview of research and clinical trials for a non-invasive, vibrotactile coordinated reset stimulation for treating PD.
The speaker was:
Peter Tass, MD, PhD, Stanford Neurosurgery.
Visit the Palo Alto Parkinson's Support Group
med.stanford.edu/parkinsons/n...
Stanford's APDA Information & Referral Center and Stanford Parkinson's Community Outreach coordinate a local Parkinson's Disease (PD) support group in Palo Alto. Since March 2021, we are meet virtually, highlighting local resources, Stanford healthcare professionals, and Stanford research.

[@MrManidos]

An electronics hobbyist can build such a glove provided that they have the researcher's data on the vibration force and timing. This DIY device most likely will not have a polished commercial look, but I do not see why it won't be as effective as the one used in the trials. People are desperate for this treatment. Please, open source the research data and let anyone experiment at home. Millions of people around the world would quickly pinpoint the exact settings for the optimal result. Thank you , Prof Tass!

[@mikeweber4677]

Agreed

[@bethwokabi6268]

agreed

[@darelark]

Here is an arduino mimicking and illustrating with LEDs the sequence of stimulation they are using. It now appears unlikely that the button vibrators used in cell phones will work. They will stimulate too many neurons. But I am now looking for piezo electric devices (read mini microphones) that produce tones of 250 hz. The 660 milliseconds is easy but his statement about a total of 1.5 hertz of stimulation is currently stumping me.

[@lewisbob51]

Please keep us informed as to when this will become available. This desperately needed!

[@bethwokabi6268]

@@darelark keep going, you will get a break through. read the research papers and watch the other videos. all the best and please keep us posted!

[@Had2Listen]

I have reached out to the team at Stanford. They responded with a very blah blah blah answer as to getting into the clinical study and speeding up availability. The videos and the data are impressive. My wife has PD now 10 yrs. Praying good news soon !!!

[@gailmarieerlandson66]

I am ready to try this! Bring it on!

[@2000mbhatti]

I worked with Prof Tass in Germany... he is a great guy...wish him all the success!!

[@nitinchoudhari5647]

Please make it available at the earliest, many need it , can't you speed up the approval as it is non-invasive.

[@Shagart8872310]

The researcher's extraordinary approach to the insoluble problem of the treatment of Parkinson's disease can lead to a fundamental breakthrough in the treatment and innovative additions to the etiopathogenesis of the disease. Of greatest interest may be the possible modulation of dopamine levels; activation of neuroplasticity formation of neurites and synaptogenesis

[@Amira12895]

Very happy to hear about the gloves.

[@SouLightness]

When is this glove going to be available for the general public?

[@antoniodealmeida1065]

summer 2023

[@JeffAnm8r]

@@antoniodealmeida1065 where did you get that information?

[@antoniodealmeida1065]

@@JeffAnm8r I looked it up on Bing search engine

[@mauijeff24]

I think the idea of them being available summer 2003 is erroneous. I've watched every single video featuring Dr. Tass and the gloves that I could find and scoured Stanford's site, and the web and found no information that corroborates availability in Summer 2023. In the Today show segment about the gloves that aired on Dec 13, 2022, the reporter commented on the availability saying, "They hope to have the gloves approved by the FDA, available for purchase in about two years." That would put availability in the end of 2024. According to Dr. Tass's statements on Twitter in Feb 2023, they will start several new studies this year.

[@doctor19741]

Are there funding issues in regards to study expansion, increased cohort numbers etc … it’s always encouraging when a trial is stopped early because of overwhelming positive effects and good safety record…. If they can introduce mRNA vaccines at a record pace then surely if this is as groundbreaking as it seems , shouldn’t there be a push to expand studies etc As a GP, I have young and old affected patients whose lives could be transformed!

[@ilyasmohammed9627]

Please launched in the world 🌎 market as soon as possible Parkinson patience are waiting desperately. Specially in India thanks

[@chriskawa3323]

Count me in for trying DIY. Ham radio operator here. I'm guessing piezo-transducers. Would need things like, frequency + amplitude of vibration, placement of vib-motors, coordination of vib among fingers (synchronous ? patterned ?).

[@bethwokabi6268]

Go for it, and share the product

[@darelark]

Here is an arduino mimicking and illustrating with LEDs the sequence of stimulation they are using. It now appears unlikely that the button vibrators used in cell phones will work. They will stimulate too many neurons. But I am now looking for piezo electric devices (read mini microphones) that produce tones of 250 hz. The 660 milliseconds is easy but his statement about a total of 1.5 hertz of stimulation is currently stumping me.

[@stellarbeaming805]

The FDA is going to make us wait forever, like they are with the CUE1, even if its not a drug.

[@bethwokabi6268]

isnt the CUE1 available?

[@endthe.1percent]

Especially because it’s not a moneymaker for big Pharma

[@user-tn1je5qx3b]

@@bethwokabi6268 only available in the U.K currently. Still pending approval by FDA in USA.

[@noreneelverrillo4690]

@@user-tn1je5qx3b are you saying these gloves are already available in the UK?

[@jonnymakers9560]

@@noreneelverrillo4690 This is completely unacceptable for the USA FDA to hold this help up..I am PISSED!!!!!

[@marvsmoir701]

Does the vibration glove approach with tactile response provide similar activity to the TENS nerve induced response

[@mikeweber4677]

How do I get on the trial listing? Why wait for FDA approval? Help is needed now😮

[@BeckyPairo]

Intellinetix makes a vibrating arthritis glove thats worth trying. If a train had some positive impact on shaking relief, Intellinetix vibrating arthritis gloves are worth trying.

[@marvsmoir701]

SO....is the drive signal frequency modulated or amplitude modulated??? What is wave / time plot ??

[@whynotmeetalan001]

I would be glad to trial this. Please let me know!

[@antonioandrino2390]

Good Morning. When do you believe this treatment will be approved? Do you intend to sell the gloves to clinics and hospitals around the world?

[@meetjohnblacksuspensenovel8091]

Are you going for FDA approval or clearance?

[@nathalie-josee248]

Did anyone tried the bhaptic gloves reprogrammed following the codes provided by Dr Tass’s lab in Stanford ?

[@nonyabeeswax7111]

Could this be a hope for huntingtons disease? Please pray it is so. Thank you all

[@jenjen462]

It appears there are no drawbacks so these need to be put out to patients immediately. Worst that would happen is nothing. As long as they don't wear them for too long which can overstimulate and make it worse

[@orakzaibarmohammadkhel6138]

I have essential tremors doctor tass as I am living abroad I want to come for treatment and I have problem in both hands legs

[@ivankos3305]

No contacts ( email nor phone# at Stanford Univ.), and no waiting list for this product.

[@user-bs4qc8gp6j]

Hi Where can i buy a pair of vibtrating gloves? looking forward to your reply with much interest!! All the best

[@Amira12895]

We with it works

[@yelenabrusilovsky9315]

I didn't wait for gloves and bought small ball, roller and platform. Use all of them during the day a few times. Feel much stronger, more flexible, more energetic. Thank you for idea.

[@clo5522]

How do you use them? Just hold them?

[@yelenabrusilovsky9315]

@@clo5522 Hold ball on hands, put roller on lap, under knees, on sides, on back. Stand on platform.

[@clo5522]

@@yelenabrusilovsky9315 thank you so much. Cheers

[@noreneelverrillo4690]

Is this effective? How long do you hold them? What do you mean by roller and platform? How do you use them? I appreciate you sharing. Thank you.

[@yelenabrusilovsky9315]

@@noreneelverrillo4690 Vibrating ball, roller and platform. You tube doesn't let me to give link. Look how they work here and find where to get.

[@sureshbagal6674]

Will it be available in India?

[@AngunyAnguila]

日本語で映像内容を　ざっくりまとめると　別々に動くはずのシナプスが同期して異常反応してしまうのがパーキンソン病。脳深部刺激療法で特定のパターンのパルスを流すと大きく改善される。しかし手術など患者の負担は大きい。 タス先生は、大脳の感覚野，運動野に注目した。ペンフィールドのホムンクルスにあるように，手の感覚に対応する大脳の面積・エリアは大きい。手に刺激を与えれば大脳の広い範囲に良い影響を与えられるのではないか？と手袋から同じパルスを送って過激を与えたら脳の活動が明らかに変わり、患者も改善された。という。素晴らしい。

[@avinash1057]

How to contact Pro Peter Tass to have the treatment?

[@owenhas9029]

Hmm...interesting if artificial intelligence could analyze the data and optimize the vibration pattern for each patient.

[@martincameron7996]

Can it be use if a person has DBS? Or, does the DBS needs to be turned off before using the glove?

[@stanfordapda923]

This is a good question. Can you ask if of Dr. Tass?

[@donawalt7097]

Is there data showing 13K vs 15K motor frequency? I am using the 13k motors because that is all I could find but are the 15K motors more effective?

[@stanfordapda923]

Suggest you contact Dr. Tass with your question.

[@francolsh]

Waiting for the equipment

[@user-vs5ih3sl3x]

Onde tem esse tratamento no Brasil

[@tomhuffinton5193]

Do you have to be off meds to get benifets or this? Also, why no thumb?

[@stanfordapda923]

Please ask Dr. Tass this question.

[@susanfischer6155]

What about atypical Parkinson’s

[@florantemendoza4185]

We here in the country Philippines are much waiting for the that device as early as possible pls

[@orakzaibarmohammadkhel6138]

How to contact Dr tass for treatment

[@Lenteja77]

How long until this device is available??

[@user-bs4qc8gp6j]

did you get an answer???

[@Lenteja77]

@@user-bs4qc8gp6j no

[@samstagnitti547]

Are there any trials taking place in Australia ?

[@MyrnaLittell-xv2kj]

Is this available to the public now?

[@stanfordapda923]

No. The glove is still being studied.

[@lina-ib8oo]

belinya di mana

[@cullylee8092]

Would a common person be able to afford the glove or will need to go to clinic ? If so , would someone is on disability be provided with insurance?

[@lina-ib8oo]

@@cullylee8092 l come from Indonesian

[@stanfordapda923]

This glove is still being studied.

[@antoniodealmeida1065]

hold on is he saying deep brain stimulation and the gloves do the same thing ???

[@ravindrakango6266]

Today it is close to 1 year this video was posted here but no further discussion or updates posted as to what happened to the 3rd clinical trial, when can we hope to reach the target end-users, the millions of PD patients world-wide. I request Dr. Tass and team to post updates ASAP.

[@stanfordapda923]

Please contact Dr. Tass and team directly.

[@kennethmcormick-nj1kv]

I want to get tthe tre atment

[@susanfischer6155]

Parkinson’s plus ?

[@harjeetsingh-tp5re]

Pl expedite availability of gloves in market for parkinson's patients.

[@susanfischer6155]

Treat Not cure

[@trents5864]

Horrible audio