A2 Biology - Cholinergic synapses (OCR A Chapter 13.5)

[@joeylawson6964]

I must have watched at least 50 of your videos over the last couple of weeks! Thank you so so much, you've made me feel less anxious about my upcoming assessments !!! So clearly laid out and explained and I always like the summary you do at the end.

[@BioRach]

I'm so glad that you've found the videos helpful!! All the best with the assessments - you can do it! :)

[@Akman006]

mums

[@DrBiology3]

This is an excellent summary - can be used for AQA A-level Biology Synpases too. Thanks BioRach.

[@estherffff]

We love to see it Rach!

[@orikatz8425]

This is an unbelievable explanation!

[@aysha64]

Omg my teacher just took this topic today but honestly didn't understand a single part but now fully clear🙌THANK YOU miss

[@yasminbegum2618]

i love the visual explaination and your recapping on what you've explained!

[@joumaalmohammed2172]

I'm at uni, and this is a great video for a quick revision.

[@NdayisabaTheonest]

Thanks my friend I am going to follow you every day

[@marriyahirfan3151]

So simple yet Helpful !

[@tsuki2480]

Amazing explanation!! Thank you so much you’re a life saver ❤️❤️❤️

[@Soloman827]

You are seriously a legend!

[@WatasaLeevan]

Thx u very much

[@Kurdistanijwan2024]

best video ever

[@osnatcsillag8596]

Amazing, Thank you

[@hofficial1332]

Hey, at 4:30 - 4:40 range, Do Ca2+ voltage gated channels open because the membrane becomes depolarised or polarised? Sorry i can't understand it clearly

[@BioRach]

Ca2+ channels open when the membrane is depolarised - which is when an action potential arrives!

[@chiazokamprecious4320]

Thank you so much this was very helpful.

[@saitaha4392]

Brooooo helping mee with my exam tommarrow

[@H4HARUN]

Hey, im not 100% sure but i remember something about chlorine molecules being released out of presynaptic neurone while acetate and choline diffuse in so balance out electrochemical change. I haven't seen that in this video and I'm wondering if i am wrong @biorach

[@fatk248]

4:30 the polarization or the depolarization??

[@Dr.Zubair]

Conversion acetyl and choline to acetylcholine occurs inside matrix of mitochondria or outside or between membranes?

[@munaaliii]

Very helpful thank you

[@nadeen-2867]

thank you so much

[@noahchitty6119]

that was so helpful thank you so much!!!

[@nadeemnaseem6994]

Very helpful .

[@rameenrayha]

Thank you!

[@kurapikakurta503]

watching this vid 3 days before my test 😭😭

[@AkashAbdullah-e3t]

Watching this at 12:20 when i have the final exam at 8:00.

[@flowerhunter]

yeah they asked an MCQ about GABA in the october exams

[@dionsilverman4195]

How do acetycholine and acetate diffuse back into the presynaptic neurone? Do they diffuse through the membrane, through channels? The diagram looks like they get endocytosed. Is this receptor-mediated?

[@BioRach]

I'd suspect it would be via endocytosis or channel proteins, given the size and likely charges.

[@janaasser5462]

Thank you❤️

[@sarahxox3202]

I LOVE YOU

[@sffiyah.88]

I have a quick question. Wouldn't the ACh be released from the cell surface membrane via exocytosis as its a vesicle being released from the presynaptic neurone?

[@BioRach]

Yes that is correct :)

[@sffiyah.88]

@@BioRach tysm for your reply!! I really appreciate it

[@dextersykes]

Cheers for the video, very clear and helpful, I think you’ve spelled synapses wrong in the title unless that’s an American spelling, thanks

[@BioRach]

Well-spotted! Thanks for telling me that, I've corrected it now! :)

[@soyadrink9831]

❤❤

[@fiddlesticks6146]

thank youuuuuuuuuuuuuuuuuuuuuuuuuuuuuuu

[@72jameskay]

Finally understand this lol

[@sabrinaduncan128]

Very helpful thank you

[@user-kx6sl2sr7u]

So helpful thank you