Huntington's Disease

If your parent has Huntington’s disease, then you have a 50-percent chance of inheriting this progressive brain disorder. What exactly is it and what challenges do patients, their families and caregivers face? We went to the top for answers. World-renowned Huntington’s disease expert, Dr. Michael Hayden, President of Global Research and Development at Teva Pharmaceuticals, joins us to discuss the illness. Also on the show: Dr. Victor W. Sung, Director of the Huntington’s disease clinic at the University of Alabama at Birmingham and Mike Smith, a Huntington’s disease patient, as well as his wife and caregiver, Myra Smith. Huntington’s disease is a devastating neurodegenerative genetic disorder that affects movement and leads to cognitive decline and psychiatric problems. It’s a rare disease - we’re talking 1 in every 10,000 people, worldwide. However, the medical community is excited about what the future holds. You don’t want to miss this!
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[@howdytales]

Science has come a long way in helping people with movement disorders....it's about quality of life....we know how bad HD can get in Late Stages....this gives me some hope for the future kids with this gene.....great job, maybe some families will reconsider asking for help now...it's not like it used to be!

[@michellemaier2095]

It is informative for the general public, most who don't know about HD...this is great to get awareness out to the community

[@AccesshealthTv]

Thank you for your kind words!

[@salvadorhirth1641]

The following information may interest researchers: the more CAG triplet repeats, beyond the " normal " 10 to 35 repeats, the bigger the probability of a point mutation; the mere extra number of CAG repeats could create a condition where the probability of mistakes made by DNA methyltransferase enzymes acting on the cytosines in CAG triplets, could create STOP codons ( TAG ) inside the CAG repeats, when the methylated cytosine suffers a spontaneous deamination, in a rate that is beyond the cells ability to remove the T, by means of Thymine -DNA glycosylase. If my theory is correct, the existing drugs DNA methyltransferase (DNMT) inhibitors azacytidine and decitabine could slow down the development of Huntington's disease. A definitive cure would be possible if an enzyme can be created, that recognizes and cleaves segments containing more than 35 CAG repeats; I wonder if are there any identified restriction enzymes that could be modified to remove CAG with more than 35 repeats. Such CAG triplets are usually not methylated and are therefore accessible to enzymes; if a therapeutical enzyme could be produced and transported across the nuclear envelope, it might just work. I just found a link that lists promising enzymes: international.neb.com/products/r0646-ecop15i#Product%20Information I've just found this article: Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity www.ncbi.nlm.nih.gov/pmc/articles/PMC4981892/ Let's hope that more money is invested in research to cure diseases, than on weapons. Mutual understanding is so important nowadays!

[@denisemihok2296]

I was diagnosed with Chorea when I was ten.I am now 74.

[@fatimaallaizaj.jaruni8714]

Is Hungtinton's Disease the 2nd most common genetic disorder worldwide or only in a specific country?

[@lauralove1119]

my husbands father took his own life due to this disease. His grandmother also had it. I believe he was about 40 something. How does one find out if they will get it in the future? I'm very nervous for my husband. He does not show any signs. He is a computer programmer and so amazingly intelligent. I just want to be as educated as possible when it comes to this subject. thanks for this...

[@emilija74]

Laura, there is a sure test for HD, doctor can easily order it. If your husband is not showing any signs there is a good chance that he is in that 50% group that did not inherit the disease at conception. Still for his and your peace of mind it would be best to have the test done. Good luck... God bless...

[@shirleyeffner999]

To find out if your husband will get HD, make an appointment with a neurologist, preferably one at a Center of Excellence. It's a simple blood test to find out.

[@jayesimond9301]

Have children, if any, tested as well.

[@nancywalker-keay8361]

@@emilija74 4 years ago I was diagnosed of HUNTINGTON DISEASE and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including HUNTINGTON DISEASE , at first i doubted if it was real but decided to give it a try, when i contact this herbalist via his email and he prepared an HUNTINGTON DISEASE herbal cure and sent it to me via UPS delivery company service,when i received this herbal cure, he gave me step by directions on how to apply it, when i applied it as instructed, i was totally cured of this deadly disease within 1 months of usage, I am now free from HUNTINGTON DISEASE ,all thanks to Dr Joshua Ighalo. you can also reach this great herbal doctor for help . He can help get rid of yours permanently.. Also specialize in treating all kinds of illness, HERPES VIRUS, HEPATITIS B, CANCER, BRAIN DISEASE, INFERTILITY, DIABETES AND MORE. ....

[@emilija74]

@@nancywalker-keay8361 please message me at [e-mail]. Thank you. Sylvia

[@tashacherry1480]

My mother's 6 siblings all hit severe HD in thier 40s so I can't relate to this at all. And the chorea was the least of our worries. Basic things like swallowing seemed to be the breaking point for them all. I've never understood such inhumane outlook on human life and suffering as I did with nursing home administrators. NOT THE STAFF, BUT THE ONES RUNNING THEM.

[@nancywalker-keay8361]

4 years ago I was diagnosed of HUNTINGTON DISEASE and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including HUNTINGTON DISEASE , at first i doubted if it was real but decided to give it a try, when i contact this herbalist via his email and he prepared an HUNTINGTON DISEASE herbal cure and sent it to me via UPS delivery company service,when i received this herbal cure, he gave me step by directions on how to apply it, when i applied it as instructed, i was totally cured of this deadly disease within 1 months of usage, I am now free from HUNTINGTON DISEASE ,all thanks to Dr Joshua Ighalo. you can also reach this great herbal doctor for help . He can help get rid of yours permanently.. Also specialize in treating all kinds of illness, HERPES VIRUS, HEPATITIS B, CANCER, BRAIN DISEASE, INFERTILITY, DIABETES AND MORE. ....

[@tshioejeremy257]

I know a good doctor that can help you get rid of the Huntington's disease permanently without no side effects and no progeneration

[@katherinebishop392]

What is the name of the medicine you are taking

[@charlottestallion7513]

#Drisibor Alternative Herbs

[@janemike3490]

#drojeabacha

[@bothrealting2598]

hope dad don't got it otherwise 50% for me not 25 😐😬

[@tshioejeremy257]

I know a good doctor that can help you get rid of the Huntington's disease permanently without no side effects and no progeneration

[@bothrealting2598]

@@tshioejeremy257 is that possible?

[@tshioejeremy257]

@@bothrealting2598 yes it is possible. My family has been cured. WE SUFFERED IT long enough now

[@tshioejeremy257]

@@bothrealting2598 Would you like to contact the doctor that helped me . Kindly send me your WhatsApp number ok

[@bothrealting2598]

Got symptoms but I’ll get tested once I’m 18, may 2024. No one’s knows yet

[@shravangautam325]

Plz help my mother has Huntington disease and it is increasing day by day .......

[@nancywalker-keay8361]

4 years ago I was diagnosed of HUNTINGTON DISEASE and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including HUNTINGTON DISEASE , at first i doubted if it was real but decided to give it a try, when i contact this herbalist via his email and he prepared an HUNTINGTON DISEASE herbal cure and sent it to me via UPS delivery company service,when i received this herbal cure, he gave me step by directions on how to apply it, when i applied it as instructed, i was totally cured of this deadly disease within 1 months of usage, I am now free from HUNTINGTON DISEASE ,all thanks to Dr Joshua Ighalo. you can also reach this great herbal doctor for help . He can help get rid of yours permanently.. Also specialize in treating all kinds of illness, HERPES VIRUS, HEPATITIS B, CANCER, BRAIN DISEASE, INFERTILITY, DIABETES AND MORE. ....

[@tshioejeremy257]

I know a good doctor that can help you get rid of the Huntington's disease permanently without no side effects and no progeneration

[@LondenAndAutumn]

My daughter is 12 years old inheritated (Juvenile) Huntington Disease from her father.

[@Anonymous-wb6yj]

kzbin.info/www/bejne/nHWXhGaojqeSh6M

[@nancywalker-keay8361]

That's so sad to hear you are still suffering from this same disease. Am feeling for you right now, I know of a doctor who can help you get rid of this. He also help me from this same disease, He can also help cure yours permanently

[@nancywalker-keay8361]

4 years ago I was diagnosed of HUNTINGTON DISEASE and I have tried all I can to get cured but all to no avail, until i saw a post in a health forum about a herbalist man who prepare herbal medication to cure all kind of diseases including HUNTINGTON DISEASE , at first i doubted if it was real but decided to give it a try, when i contact this herbalist via his email and he prepared an HUNTINGTON DISEASE herbal cure and sent it to me via UPS delivery company service,when i received this herbal cure, he gave me step by directions on how to apply it, when i applied it as instructed, i was totally cured of this deadly disease within 1 months of usage, I am now free from HUNTINGTON DISEASE ,all thanks to Dr Joshua Ighalo. you can also reach this great herbal doctor for help . He can help get rid of yours permanently.. Also specialize in treating all kinds of illness, HERPES VIRUS, HEPATITIS B, CANCER, BRAIN DISEASE, INFERTILITY, DIABETES AND MORE. ....

[@tshioejeremy257]

I know a good doctor that can help you get rid of the Huntington's disease permanently without no side effects and no progeneration