Advanced Organic Chemistry: Oxidative Addition and Reductive Elimination

  Рет қаралды 3,459

Synthesis Workshop Videos

Synthesis Workshop Videos

Күн бұрын

Пікірлер: 3
@deltagchemistry12
@deltagchemistry12 10 ай бұрын
Great job summarizing a dense topic. I thought the video would summarize the cross coupling of palladium reactions and the mechanistic work in analyzing them. I feel like you could have compiled a more cohesive story around those seminal papers by Suzuki, Negishi, Soderquist, and Denmark. I think itwould be awesome to make a video showing the trends around Pd coupling for oxidative additon of aryl halides (EWG vs EDG which is faster) for pd reactions as these are the most used in drug discovery. Similar analysis can be done for the reducitve elimination step. Possibly even summarizing with commercially available ligands that are commonly used? Questions that can be answered are why John Phos, Dave Phose, XPhos were created? The topic of palladium catalyzed cross coupling is fascinating and a deep dive on this subject in a Syn Workshop would be great
@campbeja001
@campbeja001 10 ай бұрын
Excellent job summarizing this topic!
@nevergoonsqd
@nevergoonsqd 10 ай бұрын
Very interesting topic, thank you!
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