Cholera and G-Protein Coupled Signaling

[@GK-ef1ve]

hey I just wanted to say that you're videos are one of the reasons I passed my first year med school exams.. they're great.. thanks ( greetings from India)

[@oliversykez7292]

Once again, I am a satisfied viewer. You truly are amazing. Thank you for doing this!

[@aaronteo6624]

Thank you very much... I was having a hard time in finding cholera and cAMP animation just now~~ God bless you...

[@lavidaestaenloslibros7103]

You've saved my life and my grades

[@indranigoswami6159]

Thank you so much for this lecture. Can you please also explain about the pertusis toxin and g protein

[@shabby_bluff]

You really help my assignment. Thanks a lot.

[@WHATSUP013195]

Thank you so much! It was very clear and easy to understand!

[@genicadelara5243]

Thank you so much. Very clear explanation.

[@duyanhang854]

We know that CTX and PTX can be used to asses the involvement of G proteins in signal transduction pathways but an exp said that if G proteins were involved in a new cell signalling pathway that neither toxin had an effect. Could you please help me to explain ?

[@AhmedX177]

Thanks a lot, I have had troubles understanding G-Protein coupled receptors

[@medicinelikeapieceofcake2801]

Thank you sir that was very helpful but what I didn't understand is that why when chloride and sodium channels are opened the ions move from inside to outside of the cell? They should move down their concentration gradient which is from the outside to inside, aren't they?

[@kasojuvamshi7926]

Na ion concentration is higher extracellularly,inhibiting its movement into the cells by inhibitng Na-H antiport,Na is not absorbed,and chloride concentration is higher inside the cells,opening chloride channels leads to loss of chloride ions along the concentration gradient into the lumen,net result is loss of Na and Cl ions along with water causing diarrhoea.

[@satyambhola5187]

Awesome video sir ☺🙏🏻

[@Perizeh]

Fantastic video. Absolutely loved it. Thank you!

[@sunnie7368]

you are a genius

[@tar_las]

Amazing video. Helped me so much !!

[@132mohamedhakkim2]

Super sir....ur videos really amazing.....make more and more....we always support you

[@TamingTheJump]

This was awesome! Thank you so much!

[@robertcoyle1532]

So what's in this for ol V Cholera? Not just salt water I expect.

[@kathyc3005]

Great explanation, thank you so much!

[@khadijah4735]

Thank you foe this great explanation.

[@DT9996]

Sir please post videos on cdk kinase activities at each cell stage of cell cycle n its mechanism

[@Sneha-Anatra]

this mans about to end my biology professors career

[@patchvillenas1924]

HELPFUL!!!!! THANK YOU!

[@valeriavazquez6638]

why is there a low blood pressure? Is it because of osmosis? Can someone please explain this to me in detail

[@khadijah4735]

because of the severe diarrhea which will decrease the blood volume then blood pressure will decrease.

[@khadijah4735]

the cholera can be severe that diarrhea may reach 1 liter per hour, and its too much. this loss of water will lead to dehydration and will decrease the blood volume a lot which will decrease the arterial pressure. the loss of blood volume will reach a point that even compensatory mechanisms of the body ( sympathetic nerves system, secretion of renin and vasopressin and others) cannot maintain the arterial pressure anymore. this will lead to circulatory shock and loss of consciousness and eventually death.

[@kainatahsan2782]

sir ap enzyme classification py be videos upload kren

[@alicanguran8577]

Thanks for the helpful video but: does the adenylate cyclase actually localise to the membrane like shown in your diagram? Isn't it in the cytoplasm rather than spanning the membrane like shown here? Thanks.

[@shivamdixit5860]

Yes, AC does localize to the membrane.

[@yogayantra]

Thank you so much.

[@hanireni3930]

Thank you! This really helped me a lot :) Keep it up :)

[@hushamahmed9063]

Very helpful

[@marlenekon4392]

YOU ARE AMAZING~!!!

[@thedarklightwendigo1417]

no idea what was going on but liked it anyway

[@26dikshaghunowa2]

Amazing 🙌

[@hadizajibril5428]

Thank you. Very much!

[@anamikapal2422]

they r gram negATIVE and appear pink under microscope due to the gram staining counter stain saffrain . their natural colour is not pnk :] love

[@padmasree4720]

omg it was an awesome class

[@MrGhali09]

There are two A subunit not one I think

[@PaKiKiNg908]

Thank you so much!!!!!!!

[@priyankajagan5208]

Thanks alot

[@269Tanya]

THIS IS GREAT!

[@kathmandunepal9547]

Aa-mazing!

[@kudakwashemalombola2755]

wow

[@malloryos]

you rock

[@andrewshabatunichka1785]

6:20 fuckn protein)))