G-Protein & G-Protein-Coupled Receptors (GPCR) | Cell Surface Receptor | Physiology | Endocrinology

Biosignaling...G-Protein & G-Protein-Coupled Receptors (GPCR) | Cell Surface Receptor | Physiology | Endocrinology.
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[@MedicosisPerfectionalis]

🐳 Kidney Physiology: www.medicosisperfectionalis.com/

[@lakep7798]

Wish there were Nobel prizes for breakthroughs in using YT as an educational platform for science. You, Sir MP, would be a shoo-in!

[@MedicosisPerfectionalis]

Thank you so much!

[@ashleyleonard94]

Words cannot describe how thankful I am for this channel!!

[@MedicosisPerfectionalis]

I am thankful for your comment!

[@ThatsWhy-]

My great Dr... you truly deserve Medical-Science Teaching Award . Bravo

[@MedicosisPerfectionalis]

Thank you so much, dear!

[@ThatsWhy-]

I swear to God you deserve more . You are just great phenomenon .

[@MedicosisPerfectionalis]

😊😊

[@ThatsWhy-]

@@MedicosisPerfectionalis at the minute 24:08 , gastric acid secretion is by Gs coupled ? Should not be by muscarinic receptor M3 Gq coupled ?! I am confused with Histamine functions!

[@SubhrodeepBandyopadhyay]

@@ThatsWhy- I think H2 receptor by histamine and M3 by Ach both causes gastric acid secretion and they are Gs and Gq coupled respectively.

[@golbomedia]

ı never have the tolerance to listen to my professors for 20 mnts😂 but ı can sit the whole day watching and listening to your vedios, hilarious and gifted😊

[@MedicosisPerfectionalis]

I appreciate you so much!

[@chiomagini1187]

Now, that's a quote, "the best pneumonic is understanding." Best explanation yet. Thank you for all you do

[@MedicosisPerfectionalis]

Thank you :)

[@viktoriavarga9101]

Perfectly explained. I've been rereading my textbook for ages, but it only clicked when I could visualise the processes through your drawings. Many thanks!

[@MedicosisPerfectionalis]

You’re very welcome 😊 Thank you so much for watching!

[@beatricecajetan2632]

I have a lot of love for this channel. Thank you so much for all that you do and continue to do!!

[@MedicosisPerfectionalis]

You are so welcome!

[@bigal9487]

No way u just explained that in 5 minutes at 2x speed and when i go to class, my professor doesnt explain it that easily. Bless you and your lineage

[@MedicosisPerfectionalis]

Thank you so much for watching! Please help me by sharing my videos with others!

[@seabids]

The reason your content is so amazing is because although it gets really specific, so we can understand in a reasonably deep way these biochemical mechanisms, it doesn't go unnecessarily deep, like what we can find by reading Goodman and Gilman's (I mean I love it but the text is just too long), you give exactly what I need to study for the masters entry exam I'm preparing for. Thank you so much!

[@MedicosisPerfectionalis]

You’re very welcome 😊 I appreciate you, Darlan! Good luck 🍀

[@hanamov9921]

what an amazing teacher you are. you are excellent

[@khkhmoh4651]

diction and voice 100% Explanation and simplification of the information 100% writing, drawings and colors 100% sense of humor 😂 100% Great Thank to you good luck Keep up 👌👍

[@MedicosisPerfectionalis]

Thank you!

[@radhini5125]

Thank you so much for this!

[@samhouston1483]

Coming here to learn abt GPCR’s after I have been dealing w hellish Long Covid for 16 months now..some think GPCR’s are involved in this and there’s a clinical trial using an aptamer to act on GPCR’s. Hoping for the best

[@mejojo924]

You are the absolute best!!!!!!!!!!

[@BareerahNoor]

perfectly explained every step thank you so much

[@MedicosisPerfectionalis]

My pleasure 😇

[@anisaaina4067]

its really amazing lecture.

[@SkyAssassin9]

You are a genius guy, ty

[@morvaridashtari8636]

I love your videos. Learn and laugh at the same time :D THank you

[@MedicosisPerfectionalis]

My pleasure 😇

[@zainabelamin9892]

One of the greatest videos on youtube!

[@MedicosisPerfectionalis]

Thank you so much, Zainab! I always appreciate your comments!

[@raviv133]

Thank you so much for your video! This makes so much sense! I was wondering if @19:52 you meant to write M2 and M4 are Gi --> which inhibit the sympathetic system because in the video it says that it inhibits the parasympathetic system?

[@berjemijares205]

I just can say: I LOVE YOU !!!! thank you so much !

[@MedicosisPerfectionalis]

Thank you for supporting my channel by being a member!

[@aragamsubbarao5912]

you are a great teacher.Thank you,Sir.

[@MedicosisPerfectionalis]

My pleasure 😇

[@ananyagupta9730]

Wow thank you!!

[@MedicosisPerfectionalis]

My pleasure 😇

[@mrmc55]

when i stuck at school , the first thing comes in my mind is to vist your tutorials, i really appreciate them they are amaizing...!

[@MedicosisPerfectionalis]

I am so happy to help!

[@mrmc55]

@@MedicosisPerfectionalis thank you so much your videos they are very helpful, here is the feed back of last semester i got "A" in microbiology and "A" in biochemisrty because of your Toutorials. again thank you so much and be blessed...😊😊😊

[@robindcole]

I hear your voice in my head when I study. This is good. ❤

[@MedicosisPerfectionalis]

Wow 🤩

[@lionsinescanor373]

Solid video yet again!!

[@MedicosisPerfectionalis]

I appreciate you!

[@user-ot9cn5le2i]

i highly appreciate your videos

[@MedicosisPerfectionalis]

I appreciate you too!

[@yasseralfaki8839]

This realy is the basic medicine Will never find like this teaching, thanks

[@MedicosisPerfectionalis]

Glad it was helpful!

[@shujighale5258]

Great video as always. Never Disappoint

[@MedicosisPerfectionalis]

Thank you 😊

[@muhammadaliaslam4023]

Great 💜❤️❤️❤️ I understood what the Flip You were Talking about 🤣

[@MedicosisPerfectionalis]

Amazing!

[@passntesam3346]

I really can’t thank you enough ❤

[@MedicosisPerfectionalis]

My pleasure 😇

[@nadaesawy7810]

"It is a very simple concept but it is just that your work professor can't teach" that hit me badly lol

[@kauserfayaz4586]

🙏 thank you your video saved me

[@MedicosisPerfectionalis]

Thank you 😊

[@abdelrahmanmetwally8976]

No surprise , another class 👏🔥

[@MedicosisPerfectionalis]

Thank you 😊

[@ABC-fv7ow]

Awesome presentation

[@MedicosisPerfectionalis]

Thank you 😊

[@shams8917]

Pure gold✨

[@MedicosisPerfectionalis]

Thank you!

[@besttiktoks4352]

THE BEST!

[@MedicosisPerfectionalis]

Thank you so much ☺️

[@heliagolestani]

Best explanation ❤

[@MedicosisPerfectionalis]

Thank you so much, Helia!

[@emerszon76]

You're right!!!! my professor can not teach this!

[@MedicosisPerfectionalis]

Thank you for watching my videos! I wish you success!

[@nishat_zaman]

this lecture was really entertaining

[@MedicosisPerfectionalis]

Thank you 😊

[@xaaboopinkly]

Thanks 🙏 💕 ❤️

[@MedicosisPerfectionalis]

My pleasure 😇

[@msasyhero7559]

Dr I really addicted to your way in teaching, do you have pathophysiology videos? 💜💜🦋

[@MedicosisPerfectionalis]

Thank you so much 😊 What specific topics in Pathophysiology?

[@sozi4271]

Thanks 💗:)

[@MedicosisPerfectionalis]

You’re always welcome 🙏

[@ayeeejinny]

you are a genius wow

[@MedicosisPerfectionalis]

Thank you ☺️

[@Priya__Arora]

Finally I understood G protein Thanks a lot

[@MedicosisPerfectionalis]

My pleasure!

[@Yousha999]

Thank You for the great well explained videos .I was looking for a video that explains G-Proteins. Can you please make a video on Arsenic poising and how it affects the TCA cycle?also on mercury poisoning and its affects on the enzymes? Can you also please make a video that revises TCA cycle and Glycolysis and gluconeogenesis?

[@MedicosisPerfectionalis]

Thank you so much for letting me know!

[@rukaiyagulzarali]

Amazing 👌👌👌

[@MedicosisPerfectionalis]

Thank you 🙏

[@shayannikeghbali]

Hey, thank you for your awesome videos i have a question, hope you can help me: 1. β1 stimulation :: Gs :: ⭡ cAMP & PKA :: ⭡ Ca in myocytes :: ⭡ Contractility of (cardiac) muscle Q1. so as β receptor stimulate Gs, does it mean all β receptors (β1,β2,β3) would ⭡ Ca in the effected tissue? for instance, due to Gs pathway, β1 stimulation makes ⭡ Ca in myocytes. so does β2 stimulation makes ⭡ Ca in vascular smooth muscle too, as it use the same Gs pathway? in the video you had written β2 stimulation would "inhibit myosin light chain" in VSMCs. i know the fact that β1 is dominant receptor in heart & β2 is dominant receptor in VSMCs, but my question is when they (β1&β2) both use Gs::cAMP::PKA, how does one receptor knows to make "⭡Ca" and another knows to "inhibit myosin light chain" in the cell? Do their Gs differ or do their PKA differ from each other? i hope you can help me to know what i am missing here best regards

[@user-ru3pw3bk2k]

The best ever

[@MedicosisPerfectionalis]

Thank you!

[@cezzane_o11o49]

btw thanks a lot, I have a question about gastric acid secretion, of course, Gs is a cause of vasodilation and also smooth muscle relaxation then it means the mechanism of H2 cannot contract the smooth muscle of the gland which releases gastric acid now how to release gastric acid without contraction of the smooth muscle

[@maarenvanhenden5728]

Al or nothing

[@allencrider]

I always appreciate a little dopamine from time to time. Is it true that insulin can (will) put glucose into an adipose cell?

[@MedicosisPerfectionalis]

Yes, it’s true!

[@doodoobearlove]

thanks for real life saver professional better than school professor's goddess on youtuber make textbook into less than half hr vdo and immediately connecting whole pic that helps us get connected with all the critical concepts! thanks for make everything so clear! watching your vdo once is saving me reading my teachers books for days and still messy not sure what they try to deliver as key point or larger scope concept! and btw 15:32 the GDP was replaced by whole GTP not just Pi.

[@sevaraniyazova3663]

Waaaauw!!!!

[@soumyaranjanmishra6351]

Hey ❤️,Can you please make a video on "Ovarian Cancer"

[@MedicosisPerfectionalis]

Thank you for letting me know!

[@jamalshah166]

Pro level

[@MedicosisPerfectionalis]

Thank you!

[@tallonmuhlestein3162]

You have done it again! Made my day. “G-protein, why not F-protein for ”F me.” Hahaha!

[@carinat3365]

🙌🏼

[@MedicosisPerfectionalis]

Thank you 🙏

[@sayalidiwakarwani6313]

❤❤❤

[@MedicosisPerfectionalis]

Thank you 😊

[@patrickjoshuapascual2685]

19:55 Gi-inhibition of parasympathetic function??? Bradycardia is not characteristic of para action. ty

[@MedicosisPerfectionalis]

I meant to say that Gi is responsible for the inhibitory functions of parasympathetic actions.

[@fatehakhanam8261]

13.50

[@malinduanjana3071]

You said that "all enzymes are proteins" I have learnt that some RNAs are also enzymes! So is that wrong?

[@ZahdShah]

I have not heard this before. Where did you learn this?

[@malinduanjana3071]

@@ZahdShah from my biochemistry lecturer !

[@Yousha999]

From my PhD experience in Biochemistry Yes that’s true. Ribozymes , Ribonuclease P are example of enzymatic RNAs that are made of RNA and there are very few non proteinous enzymes like this the majority of enzymes are made of proteins after translation.

[@TT-vd7sf]

Quite simplistic and incomplete

[@arpitdharmani8015]

🤦🏻

[@rabbigamer7989]

Can you please tell me relationship or difference between gpcr amd adenosine receptors