Aldosterone removes acid from the blood | Renal system physiology | NCLEX-RN | Khan Academy

[@jrask]

Yea this video deserves waaay more love. Thank you Rishi for helping me see the forrest through the trees!

[@blairburgess4898]

Great video! You explain things really well!

[@trayc8710]

this video made everything so clear. thank you!

[@languageandmana9255]

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[@nellysexy40]

Thank you so much

[@koszhar]

In my textbook of medical physiologyboron it says that the B intercalated cells secrete HCO3- And the A intercalated cells secrete H+ and reabsorbs K+ But GREAT video!!!!

[@4sHiZzLeMaDiZzLe]

Well, it does exactly that. Alpha intercalated cells secrete H+ into the urine, while reabsorbing K+, thus making the urine acidic. "Reabsorbs" implies that they're referring to the nephron.

[@hh-zq9io]

Super like...thank you

[@taulantmorina685]

Thank you

[@debfryer2437]

Where does the acid in the blood come from? Can it be adjusted through diet? Is it produced by ingesting too much acid in the diet eg vinegar?

[@Dan0rioN]

So if I understand correctly, Sodium helps transport blood acidity into urine?

[@alexanderstrau4135]

6:04 why can't the bicarbonate react with the same proton in the cell to neutralize it?

[@ss4adam]

im confused on this as well. i guess no one knows the answer

[@Jaytriple1]

adam kim Alexander Strauß - the bicarb diffuses out into the blood (down its concentration gradient) to neutralise the H+ there.. there is no bicarbonate left to neutralise the H+ inside the cell. Also more importantly, the reaction that you are asking about not happening (reverse of carbonic anhydrase reaction) is MUCH slower than the forward reaction as enzyme is not present - so this will not happen as it is easier and quicker for bicarbonate to diffuse out of the cell and H+ to go into the urine. Hope this helps!

[@kylehallas2011]

Alexander Strauß it would make carbonic acid, which itself would cause acidosis.

[@gearhead1302]

@@Jaytriple1 perfect answer! Thanks.

[@sandysanchez4]

can the A cell have too much K+? I only see it entering.

[@ucsbevan]

There are K+ leak channels to relieve the high intracellular K+ concentration

[@donatreides]

From what I understand there is no H+/Na+ antiporter on the apical (or interstitial/blood) side of the α-intercalated cell. I believe that is a mistake.

[@elverchimbawe1427]

yeah baby

[@marcelaskrbin4067]

How come the H+ and HCO3- dont form carbonic acid? The same for H+ and Cl-, why dont they form a hydrochloric acid?

[@frankieroandMCR]

my notes call the alpha and beta intercalated cells type A and type B respectively... Is this technically incorrect?

[@mariozelaya2275]

Jade Davies A probably stand for Alpha and B for Beta. I think you should be fine.

[@Dan0rioN]

So less salt=more aldosterone=less acidic blood??? I have gout, which is elevated Uric acid in blood.. I feel this info could help me.. Please, it's ruining my life so bad..

[@donatreides]

Definitely go see a physician - KZbin isn't a good place to find medical advice. Having said that, backing off alcohol and meat consumption will help. Alcohol competes with uric acid for excretion in the kidney. Meat is broken down into purines which is then converted into uric acid.

[@Team_Sanatan_Army]

Didn't like... nothing about maintenance about charge??? It doesn't work like that...if a cloride is going out....some other anion has to come inside the intercalated cell...