Controlling Your Dopamine For Motivation, Focus & Satisfaction

This episode serves as a sort of “Dopamine Masterclass”. I discuss the immensely powerful chemical that we all make in our brain and body: dopamine. I describe what it does and the neural circuits involved. I explain dopamine peaks and baselines, and the cell biology of dopamine depletion. I include 14 tools for how to control your dopamine release for sake of motivation, focus, avoiding and combating addiction and depression, and I explain why dopamine stacking with chemicals and behaviors inevitably leads to states of underwhelm and poor performance. I explain how to achieve sustained increases in baseline dopamine, compounds that injure and protect dopamine neurons including caffeine from specific sources. I describe non-prescription supplements for increasing dopamine-both their benefits and risks-and synergy of pro-dopamine supplements with those that increase acetylcholine.
#HubermanLab #Dopamine #Motivation
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Links:
Review on Dopamine: www.nature.com/articles/s4158...
Cold Exposure & Dopamine: link.springer.com/article/10....
Timestamps:
00:00:00 Introduction & Tool 1 to Induce Lasting Dopamine
00:04:48 Sponsors: Roka, InsideTracker, Headspace
00:09:10 Upcoming (Zero-Cost) Neuroplasticity Seminar for Educators
00:09:58 What Dopamine (Really) Does
00:15:30 Two Main Neural Circuits for Dopamine
00:18:14 How Dopamine Is Released: Locally and Broadly
00:22:03 Fast and Slow Effects of Dopamine
00:25:03 Dopamine Neurons Co-Release Glutamate
00:28:00 Your Dopamine History Really Matters
00:30:30 Parkinson’s & Drugs That Kill Dopamine Neurons. My Dopamine Experience
00:36:58 Tool 3 Controlling Dopamine Peaks & Baselines
00:40:06 Chocolate, Sex (Pursuit & Behavior), Nicotine, Cocaine, Amphetamine, Exercise
00:46:46 Tool 4 Caffeine Increases Dopamine Receptors
00:49:54 Pursuit, Excitement & Your “Dopamine Setpoint”
00:56:46 Your Pleasure-Pain Balance & Defining “Pain”
01:00:00 Addiction, Dopamine Depletion, & Replenishing Dopamine
01:07:50 Tool 5 Ensure Your Best (Healthy) Dopamine Release
01:15:28 Smart Phones: How They Alter Our Dopamine Circuits
01:19:45 Stimulants & Spiking Dopamine: Counterproductive for Work, Exercise & Attention
01:22:20 Caffeine Sources Matter: Yerba Mate & Dopamine Neuron Protection
01:24:20 Caffeine & Neurotoxicity of MDMA
01:26:15 Amphetamine, Cocaine & Detrimental Rewiring of Dopamine Circuits
01:27:57 Ritalin, Adderall, (Ar)Modafinil: ADHD versus non-Prescription Uses
01:28:45 Tool 6 Stimulating Long-Lasting Increases in Baseline Dopamine
01:37:55 Tool 7 Tuning Your Dopamine for Ongoing Motivation
01:47:40 Tool 8 Intermittent Fasting: Effects on Dopamine
01:53:09 Validation of Your Pre-Existing Beliefs Increases Dopamine
01:53:50 Tool 9 Quitting Sugar & Highly Palatable Foods: 48 Hours
01:55:36 Pornography
01:56:50 Wellbutrin & Depression & Anxiety
01:58:30 Tool 10 Mucuna Pruriens, Prolactin, Sperm, Crash Warning
02:01:45 Tool 11 L-Tyrosine: Dosages, Duration of Effects & Specificity
02:05:20 Tool 12 Avoiding Melatonin Supplementation, & Avoiding Light 10pm-4am
02:07:00 Tool 13 Phenylethylamine (with Alpha-GPC) For Dopamine Focus/Energy
02:08:20 Tool 14 Huperzine A
02:10:02 Social Connections, Oxytocin & Dopamine Release
02:12:20 Direct & Indirect Effects: e.g., Maca; Synthesis & Application
02:14:22 Zero-Cost & Other Ways To Support Podcast & Research
The Huberman Lab Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
Title Card Photo Credit: Mike Blabac - www.blabacphoto.com

[@7575tavin]

Practical summary: 1. Dopamine management - Abstain from or limit highly desirable activities for up to a month so the dopamine levels are replenished and the baseline dopamine release returns to normal - Peaks of dopamine decrease our baseline dopamine, required to general motivation and satisfaction with life. - Go for intermittent, random releases of dopamine - Don't bundle pleasurable activities with things you want to do (gym and music) - Flip a coin and choose how much pleasure bundling you'll do to the next activity - Otherwise the activity alone becomes less pleasurable 2. Direct practices - Cold water exposure - 2.5x increase and sustained for hours afterwards - Peaks - Chocolate - 1.5x - Sex - 2x (act and pursuit of it) - Nicotine - 2.5x - Cocaine - 2.5x - Amphetamine - 10x - Exercise - 2x (up to 2x, the more you enjoy it subjectively) - Coffee combined with another activity (coffee makes the dopamine release more effective) - Connection with other people 3. Mental strategies - Subjectivity, perception and belief - Hearing something that validates our belief about an activity, makes it more pleasurable - Journaling, thinking positively about something you remember or you're experiencing now releases dopamine - Learn to spike dopamine from effort - Don't spike dopamine prior to engaging in effort - Don't spike dopamine after engaging in effort - Learn to spike dopamine from effort itself.

[@yac7571]

so we should avoid dopamine peaks from chocolate, cocaine, nicotine etc but do cold water exposure and exercise instead right? why? they peak dopamine as well -> our dopamine tank gets depleted -> our dopamine baseline is on a lower level, no? i dont get it

[@sl33pyTea]

Great synopsis 👌🏾

[@supercharging]

Otavio; While your summary is accurate, the good Professor's content is minimally accurate. Not one, rather, several of his conclusions are based on wholly inadequate controls. One phat example is using gamers' experience. Shallow achievement is a world apart from licit profit. Winning a video game has no relation to meritable achievement delivering longer-lasting or broader benefits. -- Have clicked on "free-click charity" buttons every day for about 7,000 days, and still feel SUCH a thrill at the action every day. Every click saves a life! Never a decrease in baseline dopamine. Long list of other examples. I admire Prof. Huberman enormously, and he speaks with charm and authority. That doesn't elevate his accuracy level. Your note-taking and your skills at summary are nearly exquisite. What huge potential you show. Best of energy to the best of your efforts.

[@zholnerchuk]

@@yac7571 as far as I remember the thing about cold water exposure is that it increases the baseline and has a long lasting effect. So it’s not like an immediate spike and consecutive plummeting but more of a gradual thing improving your mood and being. You might also want to keep in mind that cold water exposure has other benefits that improve your overall well-being and it can’t be compared with most dopamine spiking activities. Furthermore, cold water increases your adrenaline baseline first and it’s directly related to your dopamine levels but I forgot the exact mechanism :D

[@yac7571]

@@zholnerchuk I see, cold water exposure is different. Thanks for the answer and the details mate, cheers!

[@petsematarykeeper]

When history looks back on this time....Mr. Huberman, you will be one of the names that changed the way people see the world. Thank you for your contribution to this world. Your reach and inspiration reaches so much further than you will ever know.

[@phamawa]

He's easily one of the most important podcasts out there. Helpful info, no BS and incredibly professional/credible

[@ARNWadz]

that's why he needs to write his book...nobody knows if KZbin will still be around in the future. A book, or many, that would be his legacy

[@youtubedestroyedmylife309]

Naw I agree with petsem dude. Honestly a lot of podcasters are important and incredibly influencial in society today, and really that translates to influencing societies trends towards changing in this way or that way. Podcasting is still kind of new seeming to most people as a media platform. But overall its super powerful, cuts through bullshit that shorter more adhd-ish traditional media like television doesnt, which is usually owned by some big corperation with their own goals in mind other than educating or sharing information etc anyway. You can change the fucking world with your iphone using a fucking podcast nowadays.

[@Chrisko1492]

Dude, calm down. Yes, he does great episodes summarizing scientific papers and other work, but that‘s all he does. And he certainly won‘t go down in history by summarizing information, lmao.

[@Chrisko1492]

@@youtubedestroyedmylife309 Give me an example where someone changed the world with an iPhone. Except Steve Jobs, obviously ;)

[@tarkacode]

I am amazed by the fact that this podcast is available for free, it is pure gold

[@thobekanintuli754]

its 2hours not free

[@shinchannohara9511]

Anything changed??

[@hemuvee]

​@@shinchannohara9511good question

[@weekendmagus9994]

@@thobekanintuli754 if I pad, would it be shorter?😂

[@3drzl716]

ikr frr

[@__the_rr__]

1. Cold Water therapy effects on dopamine, adrenaline and nor adrenalin 2. Dopamine can be released in 2 ways: Local release and volumetric release 3. How pleasurable or satisfying you feel doesn't depend on peak level of dopamine. It depends upon difference in baseline level and peak level of dopamine. How you feel depends upon your previous level of Dopamine as compared to present level. Many drugs just increase both baseline level and peak level instead of increasing the difference between them. A big Dopamine release makes it more challenging to achieve higher dopamine release the next time. There should not be High level nor low level of Dpamine for long. 4.Just Increasing dopamine level will make us excited but that excitement will be for very less period of time 5. Chocolate increases Dipamine 1.5 times but it goes away in few seconds. Desire of sex or act of sex increases dopamine 2 times 6. Nicotene(smoked) increases dopamine 2.5 times above base line (Very short lived) 7. Amphetamine, Cocaine, Nicotine, Sex increases dopamine in everybody that takes them. Exercise, Hard Work and Studying increasea dopamine but it is subjective 8. After achieving something, Dopamine increases but after some time it falls down. It falls down even below the baseline. The extent it drops below the baseline is directly proportional to how high the peak was. After achieving something, if you feel preety happy, the dopamine will not fall that much but if you feel extremely happy, your dopamine will fall extremely after a day or two. (Eg:- Postpartum Depression). Anyway, we return to the baseline after some time. 9. If we continue to engage in something exciting regularly, after sometime it will be less exciting to us. 10. Some people release dopamine at higher level after a certain activity which deplete the releasable pool of dopamine. So, after sometime, dopamine falls below base level and it leads to a low feeling. Some people do the dopamine spiking activity again and again to bring back dopamine up to experience pleasure again since they are feeling low. But as we know, they have depleted the stock of releasable dopamine. The baseline begins to lower again and again. This is called ADDICTION and Addicted people don't feel pleasure at all. 11. Addiction is the progressive narrowing of things that bring you pleasure. If I am addicted to video games. I will feel happy in only playing it. I will not feel happy in exercise, study, social activity and my life will be ruined. After a some time, my system will stop releasing dopamine even after playing video games and nothing is left for me which can increase my dopamine. This is the start of depression. Spiking dopamine again and again is the main cause of decline in The baseline level. 12. If you experience a win whether it is school, sports or relationship; be highly careful about allowing yourself to experience a huge peak of Dopamine. 13. You kind of like exercise and to do exercise you increase dopamine by drinking energy drink and listen music to do exercise then you are increasing the number of conditions required to achieve the high level of dopamine by doing exercise. Don't use stimulants everytime you study or everytime you workout or anything in which you want to enjoy the process. Taking these stimulants (Music, energy drinks, Motivational reels) before the task will reduce the level of enjoyment and undermine the ability to stay motivated. The best way is to get excitement and motivation from the task itself whether it is Study or Workout. So. ENJOY THE PROCESS only. 14. Some Healthy ways to increase Dopamine so that the base level is maintained:: Cold water Therapy which increases Adrenalin and nor-adrenalin rapidly while dopamine shows gradual increase to 2.5 times above baseline and comes back to normal in 3 hours (Here there is a sustained increase instead of Rise and Crash) 15. If you work hard for the end result then the process will become very challenging. 1:39:02 is an amazing example. When someone gives reward or we reward ourself then we tend to associate our pleasure with reward rather than the work itself and if the reward is stopped, we lose interest in the process of the work. But again, Take a special care of not spiking dopamine just prior or even after to the effort. Learn to raise Dopamine from effort itself. 16. Example of Porn: Those who are indulged in it find it difficult to seek enjoyment in the productive process. Watching porn and Masturbation increase dopamine level⬆️ and then fall down very quickly⬇️⬇️⬇️⬇️⬇️ below base line . Now to raise dopamine level much higher is difficult to feel pleasure again.

[@onegorgeouschick]

Wow

[@phiphipanamevideo199]

Thank you 🎉

[@hareef.v7950]

T

[@tejiyo]

I wish I could copy paste this in my notes😢

[@egjream]

If you screenshot on iPhone and go into photos you can copy and paste the text 😉

[@catholicspaniard8796]

I am a 21 year-old engineering student from Madrid, Spain. This is unbelievably helpful. What a wonderful time we live in, that I can listen to a top-notch neuroscientist talk about perhaps the most important topic for me in this particular moment in my life. And all this from the comfort of my bedroom and for free. You, Sir, are one of a kind. God bless you and love you

[@catholicspaniard8796]

@Bernie MPMD? Lol.

[@gibillanmagnificul1160]

eres de tajamar?

[@antoniojurado6413]

VIVA ESPAÑA

[@grettalemabouchou6779]

💓

[@SuperGuanine]

@@grettalemabouchou6779 😁😁😁

[@villealla4190]

I've hurt myself and others by not knowing these things. It's borderline criminal not to teach this stuff at school. Show a teenager this one video and their entire life could be different.

[@aaronyeomans5799]

The entire system is designed to get people addicted to things they think they need that they don't, why would they teach you to be able to think for yourself and all that. That's less profitable

[@shortsguy.69]

yea its literally a crime to not teach these at school, im still a 18yo student and i found my self doing stupid mistakes in every aspect of my life

[@Sodabowski]

@@shortsguy.69 luckily you realized it early on!

[@PostAutonomy]

I have kids 7 yrs and under. I plan to start now in ways they can understand

[@jixpuzzle]

@@shortsguy.69 Same brother, I'm also 18yo student, who has realised his prior mistakes and making changes in life!

[@tick999]

I did a 10 day meditation retreat and the difference was unreal. Everything looked brighter and shiny. Even the weeds in the cracks in the paving were beautiful

[@earth7451]

Thank you for sharing this experience.

[@kaizune]

This man's existence has made my life significantly better than it would have otherwise been. Many thanks for making neuroscience accessible to laymen aficionados such as myself.

[@kaileyholmes2900]

Daddy Treehouse Canadian Television Fund

[@md.asifhossain9703]

particularly which advice did have the most impact in your life?

[@mihailomiodrag7257]

@@md.asifhossain9703 For me waking up early to watch the sunrise and exposing myself to cold showers. Also getting to sleep before 11pm. Also regular exercise and fasting with maybe some coffee.

[@diarmuidbrady8987]

This is the highest quality science-based podcast in existence, hands down.

[@spotmebro3589]

It’s so well organized and he has sufficient knowledge to present it. I’m sure a lot of work goes on behind the scenes to get it to be so smooth. I appreciate it, Dr. Huberman!!

[@misse2013]

100% agree

[@Sendet]

I, too, am particularly impressed. One thing I love is that the titles on his website seem short and gimmicky, like we're about to hear something trite and pseudoscientific, but then you start one and he goes right into very discrete definitions and hardcore science, cites his sources and even points out problems with them if any, points out pseudoscience and misconceptions... And builds up to practical uses of the information given, such that his resulting advice is neither trite nor incomplete, and not likely prone to being taken with misconceptions that undercut success of the advice or its use. Yeah. He's very good.

[@AgendaInMind]

There's no such thing that some diseases you can "catch", but not all. It's not that complex! If you can't "catch" cancer, diabetes, MS, arthritis, etc., from other people, then you can't "catch" colds, flu and Boogey Viruses. So governments around the world are CAUSING fear frights in everyone based on an unproven THEORY by one man, Louis Pastaur, who redacted his claim of the germ theory on his death bed, yet no one listened. So of course, when everyone is allowed to escape the hostage situation the governments have put their people into, and they start relaxing about the Boogey Virus, that's not in any way transmissible, they will begin their healing phase (get sick), and believe they then have it, and more panic will ensue as well as martial law. The longer people allow this government to hold them hostage in their homes, the more severe the "sickness" will be. Can anyone put 2 and 2 together to figure out what I'm saying?? Western Medicine is pure fraud, and people's lives are destroyed because of it. There's no critical thinking anymore. People think they're educated because they've memorized the lies they've been told for 100 years.

[@333btd]

Why just because it uses the science words? Those words make you feel smarter

[@ElderFoxDocumentaries]

So to recap.. 1) Don't trigger dopamine all the time, even if gained through various sources. Try to dopamine fast. 2) Cold showers can raise dopamine without the crash. 3) Don't layer in dopamine raising activities with things you want to get more motivated for. E.g Listening to music while working. 4) Don't reward yourself before or after hard activities, let the activity itself produce dopamine. Anything I missed?

[@ElderFoxDocumentaries]

Ah, 5) Intermittent schedule of celebrating your wins. Don't celebrate every time and use a randomiser to dictate when to celebrate.

[@speed747]

6) exception to the rule is caffeine (I.e coffee, tea)

[@pecoguy]

Cold showers don't last long enough for the effect of cold bathing. It's was like 20 min to 1 hour exposure at least.

[@misstrunchbull3953]

@@speed747 time stamp for that if you can? I didn't catch that one

[@northernwildshewolf1729]

Wow! Ur no fun 😂 thanks for that

[@user-zy6rb1oj6e]

How listening to this podcast boosts dopamine is unfathomable.

[@jesselam5867]

So right, I literally had low dopamine prior to listening and 30 minutes in I was feeling better

[@iggmeister4137]

I stopped and immediately felt a drop hah

[@tys.2113]

This is my first super chat. The amount of depth and knowledge about Dopamine is just insane. During covid era, I have been struggling with depression and had many suicidal thoughts its been three years still I couldn't achieve a state of calmness. Thanks to Quora I found out you (I am still a high school student ) Hope these podcasts never stop, love from India 🤗

[@marydelaney2894]

Your life will get better…life is full of lessons, keep on trucking!

[@yamu208]

Sending u virtual hugs

[@shubhamwagh5362]

@tys.2113 how are you now did your life improved are you doing well now

[@pramath6867]

I love you bro, I believe in you. Keep on striving

[@carlosmares3042]

Bro i know you dont know me but you changed my life. Saved it really. My adhd was eating me alive, i was an alcoholic, a junkie and i hated everything. Im sober now, and im in therapy….my family doesnt hate me anymore. Im actually liking life….idk anyway thank you so much. Your doing great work.

[@joepschoevaars4055]

Something similar ;) although still a bit in the middle of it 😢

[@whoosh3532]

Damn bruh i am on that shit rn hope i reap the same benefits hope u still ballin

[@artemthetrain14]

Saying s prayer for yall

[@mramenlordi3098]

Let's go folks ! Stay HARD !

[@ChrisTisking12256]

@@whoosh3532bruh. If you’re watching this, you’re already in the right direction. Props to you. You’ve already won half the battle.

[@GeorgiDimitrovX]

1:45:25 How to attach pleasure to effort: "In those moments of the most instense friction you tell yourself this is very painful and because it's painful, it will evoke an increase in dopamine release later, meaning it will increase my baseline in dopamine, but you also have to tell yourself that in that moment you are doing it by choice and you're doing it because you love it."

[@tbbbtoolsbooksbladebones556]

That's what she said.

[@shijinbadarudeen9920]

Its as if the dragon (pain) is ready for a fight with me but its ok i am ready because i am the one who provoked it.🙂

[@mihiershandilya2736]

Find Meaning in suffering

[@hsukesan]

Fantastic. Now I know why I am resilient.

[@Wildflowermiles]

Alhamdullilah, I find so much comfort in your humble transparency and straightforward nature

[@user-cs7gq9ml3u]

Through this podcast, I finally understand why everytime I play with my phone, I have no motivation to do anything else, I feel extremely low energy, that is because when I play with my phone , I experience Dopamine peak, so it is very hard to put it down.After I have to put the phone down, I experience dopamine drop, I feel worse. After I understand that, I have more motivation to leave my phone at home, I feel more motivated at work now. Thanks andrea, your podcast save a lot of people's life, I am so lucky to be one of them

[@emmanuelguillermo3013]

Your content is a game changer. Upon being prompted for a donation request I gladly sent the maximum amount, no questions asked. I wish you more success, Andrew. The human race needs what you have to offer.

[@hubermanlab]

Thank you for your interest in science! Best wishes, Andrew

[@glgl1472]

Ah the old dopamine hit

[@yooanto9465]

@@hubermanlab money talks

[@HyenaXS]

Congratulations. You just donated money to someone wealthier than you. Bravo.

[@artoniq]

​@@HyenaXS, this way, he showed his gratitude for the lesson he had received. What's wrong with you? None of your money, none of your business.

[@motomow]

I'm a recovering meth addict...3 months Sober today! Thank You Doctor Huberman for giving me the tools necessary to get my "Happy" back. Your videos on addiction and dopamine have delivered the skills I desperately sought to remain an inspiration to those I deeply care for who still suffer from addiction and who WERE too scared to take the initial steps necessary to a longer, healthier and happier future. Seeing how much happier I am and how fast my life is blossoming at 44-after doing Meth Since I was 15-is blowing minds and helping people I know who had given up rethink they're potential. Your Amazing and I want to thank you for changing peoples lives in such a noble, infectious way. Sir you are a blessing! Thank you for saving my life!

[@onerider808]

Here’s to one more day, three more months, etc. Huge life-changing win! Congratulations.

[@deklenjones3041]

hey man, i know this will probably go unread but,, good job brother. seriously, it's not easy to kick even the smallest habit or addiction, let alone freakin Meth. congratulations :)

[@kowikowi8718]

respect for you withdraw is a bitch. i can only speak for alc drinking too much much you feel sick, not drinking 6times worse. im thankfull that i didnt do "hard " drugs.

[@TatTwamAsiShwetketu]

The tools that you're mentioning, are they in this same video or scattered across multiple videos. If possible can you please share the links? Thanks!

[@ItsRealDoe]

Godspeed sister, onward!

[@danadelaney6598]

This video is changing my life. Incredibly intelligent and informative. Pretty sure my entrapment in ADHD is going to change dramatically. I’ve been living all wrong.

[@J8K1]

Just this video alone rationalized my depression. I realize now I've been chasing that "dopamine hit" most of my young adult life. Thank you, Andrew Huberman and the neuroscience community.

[@davids4253]

Actions you can take from this Lecture: 1. Avoid dopamine layering with challenging activity: Entertainment (music, smartphone, etc), substance, and social stimulants. 2. Derive dopamine from effort itself not the reward after. 3. Try cold exposure therapy and/or intermittent fasting 4. Avoid dopamine spiking drugs, sugar and pornography.

[@TiOZAO1966]

That's correct... And one needs to be a total moron to NOT get it without all of this neuroscientist crap.

[@budoka111]

Thanks 🙏

[@MrCaipiroshka]

oh... porn and sugar... hard my friend, hard to let it go.

[@incrdble9704]

@Married Texan #2 makes perfect sense for those who watched the podcast. The trick is in doing self-affirmations, i.e. you affirm yourself that you really need to do that work and/or you really enjoy that, and of course in order for that to work you should have some strong reasoning for why is it important for you and what real benefits you may get out of completing this work.

[@MrBarosxp]

avoid porn is funny as hell..

[@matthewanning9252]

Hubermanity. Giving life back to humans. Thank you. 🙇‍♂️

[@brittanynicolette9473]

Building wealth involves developing good habits like regularly putting money away in intervals for solid investments. Instead of trying to predict and prognosticate the stability of the market and precisely when the change is going to happen, a better strategy is simply having a portfolio that’s well prepared for any eventually, that’s how some folks' been averaging 150K every 7week these past 4months according to Bloomberg.

[@alicebenard5713]

Investors should exercise caution with their exposure and exercise caution when considering new investments, particularly during periods of inflation. It is advisable to seek guidance from a professional or trusted advisor in order to navigate this recession and achieve potential high yields.

[@RyanContreras72]

This is superb! Information, as a noob it gets quite difficult to handle all of this and staying informed is a major cause, how do you go about this are you a pro investor?

[@brittanynicolette9473]

Through closely monitoring the performance of my portfolio, I have witnessed a remarkable growth of $483k in just the past two quarters. This experience has shed light on why experienced traders are able to generate substantial returns even in lesser-known markets. It is safe to say that this bold decision has been one of the most impactful choices I have made recently.

[@blessingpaul5484]

Wow, that’s stirring! Do you mind connecting me to your advisor please. I desperately need one to diversified my portfolio.

[@RyanContreras72]

I’ve actually been looking into advisors lately, the news I’ve been seeing in the market hasn’t been so encouraging. who’s the person guiding you?

[@jimbrausky]

I love 1 hr or longer videos because they really go in depth into the matter

[@bhumikjoshi3430]

Why is this info not taught to all of us at a school/university level? It is beyond my comprehension. Great work Dr.Huberman! Lots of love from India.

[@BlackMamba-lt8oe]

😂😂😂😂 the country that teaches u piss and dung cures cancer, will they teach you

[@samyoe]

Deffo

[@CHIROTHECA]

why??? What do yo think the purpose of schooling is? An Intelligent population?

[@vatanc4746]

They need them worker ants brother.

[@BlackMamba-lt8oe]

@@vatanc4746 you are also worker ant

[@maxd3589]

This is the best podcast on the internet. Seriously, I can barely believe we're getting this for free. I can't say enough how much I've managed to change my health and my entire life through this podcast alone. I particularly loved the bit on caffeine. I was terribly unsure about caffeine in my life. Now I'm free to take it without stress! The coin flip tool to remove predictability is quite amazing as well!

[@sendnoodles5437]

Hey may I ask, what are a few other golden pieces of practical you’ve acquired along the way? I’m working my way through his content but I’m curious

[@danyj24]

Max- So true. Literally the best one. Comedy podcasts and sexual drama podcasts really do detrimental harm to the mind whereas this one serves to spiral everyone who listens upwards so they can chase their best self. Love it!

[@maxd3589]

@@danyj24 Yeah, it's quite astounding. Makes you feel like Dr. Huberman contributed to the advancement of the human species.

[@tarekbaidane7595]

I😀 can't believe it is for free either

[@phamawa]

I agree, its apparent hes not full of shit o imo. Huberman essentially provides you with the science based info that all the 'self help' and 'wellness' crowd tries to convey but might not fully understand. He can snuff out BS studies that others might use in their books or way of thinking.

[@dibbyarupdutta3525]

I generally don't comment on any videos but I have to say that this work by Andrew Huberman is pure gold. It gave me a fresh perspective towards my life and the things that are going on. Moreover, this video came at a time when I was not miserable but kind of not able to figure out what I enjoy doing, what I really wanted and I am in a downward spiral in my life because I don't find anything meaningful or just feel purposeless most of the time. I do understand that I am spiking my dopamine right now saying all this but I would definitely implement whatever is being advised here and see what works for me. It's like controlling the very processes that lead to how we feel, what we do, ultimately shaping our lives and if such a thing can be done for the betterment of us then why not!

[@amartya8101]

how is the process going? you feel better?

[@vankoutedar]

After listening to this podcast, I laced up my running shoes and went for a 1-hour run on the snowy former Berlin airport, -5 °C, no music and no podcast for the majority of it. I felt so damn frozen and but also so damn high and accomplished. Thank you so much Prof, for all the work you do, you are a great teacher.

[@irelax8595]

Great job mate. Keep it up!

[@Im_Tired777]

Just the beginning 💯

[@vankoutedar]

@@Im_Tired777 right, i will keep it up, aiming to run that marathon eventually, not for the sake of the marathon, but for the sake of the journey a.k.a the effort itself.

[@esteban5361]

for the effort buddy

[@Resrrekt]

Thats very healthy for your Cardiovascular system and mental strength good stuff.

[@DiariesOfAShitChef]

Thankyou for your work, releasing this free of charge is a beautiful gift to the world that is changing lives, mine included.

[@hubermanlab]

Thank you for your interest in science! Best wishes, Andrew

[@elijahmandeville8475]

I cannot BELIEVE this is a free resource. Your ability to teach and pass along information is the best I’ve ever seen. I can’t thank you enough for all that you do, Andrew!

[@user-cs7gq9ml3u]

I am a PhD student from Germany. First I want to say thanks for all the efforts you made for the podcast. I know it is one thing to understand scientific research results, it is another thing to explain in a easy way to people not in this field. But Andrew nailed, I can easily understand all the contents he said and I really like how he put everything in a smooth logic flow. This podcast is a masterpiece. I feel so lucky that I find this podcast.

[@artfender7300]

So, if sex increases dopamine 2x over the baseline and smoking 2.5x does it mean that smoking during sex increases 4.5x? and what about if you also eat chocolate at the same time 😛 Would be interesting to study such combination as part of PhD research.

[@Oldysrv]

I feel sry for ur Phd from Germany

[@kereamohau]

Timestamps: • 00:00:00 Introduction & Tool 1 to Induce Lasting Dopamine • 00:04:48 Sponsors: Roka, InsideTracker, Headspace • 00:09:10 Upcoming (Zero-Cost) Neuroplasticity Seminar for Educators • 00:09:58 What Dopamine (Really) Does • 00:15:30 Two Main Neural Circuits for Dopamine • 00:18:14 How Dopamine Is Released: Locally and Broadly • 00:22:03 Fast and Slow Effects of Dopamine • 00:25:03 Dopamine Neurons Co-Release Glutamate • 00:28:00 Your Dopamine History Really Matters • 00:30:30 Parkinson’s & Drugs That Kill Dopamine Neurons. My Dopamine Experience • 00:36:58 Tool 3 Controlling Dopamine Peaks & Baselines • 00:40:06 Chocolate, Sex (Pursuit & Behavior), Nicotine, Cocaine, Amphetamine, Exercise • 00:46:46 Tool 4 Caffeine Increases Dopamine Receptors • 00:49:54 Pursuit, Excitement & Your “Dopamine Setpoint” • 00:56:46 Your Pleasure-Pain Balance & Defining “Pain” • 01:00:00 Addiction, Dopamine Depletion, & Replenishing Dopamine • 01:07:50 Tool 5 Ensure Your Best (Healthy) Dopamine Release • 01:15:28 Smart Phones: How They Alter Our Dopamine Circuits • 01:19:45 Stimulants & Spiking Dopamine: Counterproductive for Work, Exercise & Attention • 01:22:20 Caffeine Sources Matter: Yerba Mate & Dopamine Neuron Protection • 01:24:20 Caffeine & Neurotoxicity of MDMA • 01:26:15 Amphetamine, Cocaine & Detrimental Rewiring of Dopamine Circuits • 01:27:57 Ritalin, Adderall, (Ar)Modafinil: ADHD versus non-Prescription Uses • 01:28:45 Tool 6 Stimulating Long-Lasting Increases in Baseline Dopamine • 01:37:55 Tool 7 Tuning Your Dopamine for Ongoing Motivation • 01:47:40 Tool 8 Intermittent Fasting: Effects on Dopamine • 01:53:09 Validation of Your Pre-Existing Beliefs Increases Dopamine • 01:53:50 Tool 9 Quitting Sugar & Highly Palatable Foods: 48 Hours • 01:55:36 Pornography • 01:56:50 Wellbutrin & Depression & Anxiety • 01:58:30 Tool 10 Mucuna Pruriens, Prolactin, Sperm, Crash Warning • 02:01:45 Tool 11 L-Tyrosine: Dosages, Duration of Effects & Specificity • 02:05:20 Tool 12 Avoiding Melatonin Supplementation, & Avoiding Light 10pm-4am • 02:07:00 Tool 13 Phenylethylamine (with Alpha-GPC) For Dopamine Focus/Energy • 02:08:20 Tool 14 Huperzine A • 02:10:02 Social Connections, Oxytocin & Dopamine Release • 02:12:20 Direct & Indirect Effects: e.g., Maca; Synthesis & Application • 02:14:22 Zero-Cost & Other Ways To Support Podcast & Research

[@UTAH100]

Nice job.

[@ryanstells]

Is it just me or is there no tool 2?

[@Kal-EL_Volta]

The timestamps are on the description

[@eatthewoke5170]

Thanks. This was VERY helpful!

[@rufeezo]

Tysm. I listened to the first 10 minutes and fucker still didn’t get to anything.

[@erikamarkoch6763]

I feel like these Monday drops are the glue that holds my life together.

[@laracamp2627]

i’m here for that glue!!!

[@matthewanning9252]

Me too

[@adamtomecko6817]

Beats the heck out of Elmer's, that's for sure!

[@Shadow77999]

@@adamtomecko6817 lmao

[@hailynewma9122]

hopefully you get a life real soon

[@gordonmiles6543]

Jeeze, I was accidentally doing a fair amount of this back in my college years and I loved life, was so excited for the future, was proud of myself, was excelling, everything was great. Then I left college, and because I didn't know I was doing these, my baseline dopamine just dropped and dropped, drinking, eating, loud music, etc. Now I feel like I've been re-united with an old friend who made me feel the best I ever have. Thank you sincerely. This time I'm doing it on purpose, because I want to :)

[@user-jj6ov6li1f]

Thank you Andrew and team. I have watched a small number of your videos and they are helping me to build a toolkit for myself to live well and thrive. Up until now I've been surviving and I want better for myself. I've realised that I'm otherwise in the dark. It strikes me that we've lost a lot of built-in wisdom from old generations lifestyles through our fast-paced and disjointed modern living. Your expertise and time to share the science behind thriving is a welcome antidote in a sea of confused misinformation and over-worked doctors. I am truly grateful. Thank you again.

[@user-pp3ur9co4h]

This was the most constructive and eye opening 2 hours that i had in a long time

[@sevastos2168]

wraios

[@alexluc7632]

@@sevastos2168 ελα ρε αδελφιαα

[@SaadKhan-jd9vv]

agreed!

[@eliotdiaz6896]

As a pastor who struggles every week to study for my weekly sermons and other teaching a speaking engagements, this information is incredibly valuable to me. I am on a journey of trying to understand how to be motivated and develop healthier study habits. It is so challenging for me. However my calling depends on it.

[@alexjugureanu853]

congratulations! keep pushing!

[@Sahil-jg8bd]

@@siddhantsikarwar9237 ye sab bakchodi hai bhai partner vagera ...wo bhi online...

[@havenbrauer3990]

As somebody who isn’t a pastor 😂, but an average working 19 yo trying to push through college. I’ve found that speaking to people (especially through English class) comes from “the heart.” I’ve found that when people say this, they don’t realize it, but they are saying to rather speak from calmness and resort your attention away from the constant nervous and hyperactive brain. So when he mentions that a mixture between alertness and calmness is the perfect baseline mixture for a perfect baseline level of dopamine, it’s ultimately referring to the distinguish between both I mentioned above. In conclusion, I think that is brilliant that you’ve used this podcast to improve in a certain aspect of hardships in your life and it would only be my duty to elaborate on the topic because I myself are going through a painful time in my life and I know exactly what you mean when you talk about preparing for life’s tasks.

[@composerlordrye]

Thank you Dr. Huberman for making this info available for free online and for the clear and detailed breakdown! Learned so much and already applying it in my life.

[@icanwin365]

In a world full of noise, this video is the real deal for getting your life together. The lessons hit deep and show you the way to become your best self. It's not just advice; it's a guide to dragging yourself out of the shadows and into your awesome potential. Dive in and let this be the start of your epic journey!

[@samuele5695]

I just increased my dopamine release by learning how to increase my dopamine release. Thanks Andrew

[@sticklebacketienne]

Oh yeah yeah

[@NizeBUL]

I just increased my dopamine release by reading a comment of how a person increased their dopamine release by learning how to increase their dopamine release.

[@ameliasilkworth8833]

I'm so inspired. I fed my 5 kids a low-sugar breakfast. I told them we are resetting our dopamine response by minimizing serum glucose spikes. They haven't talked to me in 3 days. Sooo... winning!! Thanks Doc!!

[@oUncEblUnt420]

Trick kids into not wanting sugar by using the food professor Huberman mentioned in one of his podcasts that flips your sweet and sour receptors(probably a freudian misattribution. The sweet and sour part)

[@actuitivevisrl1014]

@@oUncEblUnt420 using the food professor?

[@SpeedyThingGoIn4]

@@actuitivevisrl1014 I hear there's a kind of berry that does that. Just search "make sour things taste sweet" or similar and you'll find it. Now, I don't know if artificial sweeteners are healthy, or what it would be like growing up in a household where I eat a dessert berry before my sour desserts... Interesting times, these are.

[@bossgd100]

😂

[@gaberoyalll]

Lol they are probably crabby from the sugar withdrawal but will soon feel 100x better🙌😎

[@reillya.733]

Thank you so much Dr. Huberman! I have adored your podcasts! Most content these days is built upon false narratives, and are largely people's opinions over fact. Thank you for being a tool for equalizing access to education. As someone who left school years ago, and didn't follow the path of academia, I am so so grateful that I can still learn and expand my mind through your podcasts. Thank you! keep doing what you do!

[@lunarribbon917]

Dr. Huberman, thank you for existing and wanting to help humanity! I just discovered your channel and am extremely fascinated by all this helpful content you present! You explain concepts in a very clear and interesting way, also using recent studies from prestigious medical journals to present facts and ideas in non-biased ways, allowing us to utilize this information to improve our lives. Part of depression is not feeling any joy or motivation for anything (even for things that we once found enjoyable), because it's not engaging as it was before, and there's a lack of meaning or purpose behind it. Especially for high achieving people, always accomplishing at their highest level, and there's always that underlying question of "what's next?". Part of it is needing extremely high levels of a certain substance/drug/activity in order to feel joy and excitement, and if we can't feel that "high" anymore, then what's the point of wasting our time and energy searching for these highs that never last and these lows that only continue to worsen. Everyone experiences depression differently, some might feel persistent sadness and guilt, while others will feel baseline neutral to everything (even if its something considered pleasurable, like sex/alcohol/drugs/eating your favorite food, etc). Like you can literally get a high raise/promotion and still feel "meh" about it.

[@ubiqanon6405]

Fascinating that so much of this seems to reinforce some eastern philosophy ideas - embrace the suffering of the moment for what it is, be comfortable with experiencing suffering as life is comprised of both suffering and joy... the goal is not to seek happiness in itself, but to let it emerge from the pursuit of meaningful / effortful things. The pursuit of pleasure / reward for its own sake is counter productive and ultimately self destructive. This reinforces Dr Gilbert's work on happiness as well.

[@ElectricFuture]

I got in the habit of exercising first thing in the morning. It was my favorite part of the day. Big energy drink, playing my favorite music, jogging by the water maybe some weightlifting. I’d feel great during, flooded with ideas and inspiration, but then afterwards When it came time to sit down at my computer and do some work for the day i’d feel a bit…uninspired, burned out. I never put two and two together because I’ve only heard exercise is supposed to be healthy and great for mindstate. But I think I may have just had a realization, need to shift my schedule around and save some dopamine for mental effort as well.

[@sarahzmayfitness]

@Dave How do you implement that, if that is time you have? I feel the same way with exercise... I feel like I accomplished a lot afterwards, but then feel the crash. Maybe I just need to see exercise as a means to an end, and not a reward? So I don't get that crash?

[@austinheyman]

@@lowaimnobrain i agree the energy drink has to go first, then you should see if you experience the same effects without the energy drink. Otherwise, there are too many variables. Don’t forget that you also have to enjoy it! Satisfaction from different forms of exercises are subjective to different people so find what fits you best, try some variation in how you move your body and and keep it interesting!

[@andrewconnor4429]

Consider on top that there are ultradian rhythms plus your expectation so you're training your body "at this time we are going to do some great stuff, at this time we will sit down and do the grunt work" so in a way you're training your body to be dull at that time, if you sit down to work at your regular running time, then go work out at your regular sit down time, what happens? Probably a great computer session and an uninspired workout? Maybe!

[@BlakeAndrewz]

Lay off the energy drinks I'd say

[@ghostwriter8351]

I have good results from writing first then exercise. Not only is my half asleep mind more creative, but it's also full of potential energy. After my minds fatigued I start exercising to circulate the blood. I sort of cycle on and off with writing and exercise. But everyones different

[@Username4453]

As a former video game addict, I thank you for this video. I've been wondering why i'm so unmotivated and this explains a lot.

[@ellah.villar04]

I have Hypothyroidism and will stop medication (L-thyroxine) for the next two weeks for my scan, and am currently addicted to my phone (9 hrs+ average screen time). With this information I could expect and leverage the side effects in the next two weeks, and now understanding how I could control my addiction tendencies will help me get thru this. Thank you sir.

[@strahinjajelic869]

Just to recap for the people who don't have time to go through whole thing: 1. go through whole thing it's pure gold 2. Thank you Andrew, you are the best there is!

[@Dominickq]

This was incredibly generous and packed with information. An online masterclass like this would be sold for hundreds of dollars, and you've shared it for free. Big gratitude.

[@ilyashu.3247]

This is gold. For those electrical engineers out there, I've came up with a boost converter circuit analogy for the dopamine system. Input Voltage (from Current Limited Voltage Source) -> Dopamine baseline Input Capacitance -> Dopamine storage element in organism Voltage Source Current Limit (connected to input) -> determines the rate of charge (dopamine) restore in the Input capacitance or equivalently, how quickly dopamine baseline is restored Output Voltage -> Level of Motivation / Drive / Happiness Main Transistor Duty-Cycle -> controls the spike of voltage on output (Level of Motivation / Drive / Happiness), controlled by our nervous system Inductor -> determines how sensitive will be duty cycle changes (resulting increase in Motivation) Using the model (Examples): 1) Effect of cold exposure -> increases the voltage on input source 2) Effect of dopamine spike as a reward for something -> Depletes the stored charge (dopamine) in the input capacitor, which results in the temporary input voltage decrease (baseline drop). This happens since the voltage source is current limited (dopamine production / rate of restore is limited).

[@parkourenthusiast8756]

Thank you so much. I am 18 years old, in college and am learning so much valuable information from your podcast. Your podcast really has really helped shape me into a more healthy person. I know you have separate videos covering the subject of marijuana, however I can’t help but point out it would be really interesting if you made a video talking about marijuana and it’s direct relation and effect to our dopamine and epinephrine levels. Thank you again :)!

[@medmahi241]

❤❤❤

[@ameurchafa1961]

he did it

[@codinginflow]

Maybe this explains why, after having some really good, highly productive days, I sometimes get single, really bad, depressive days where I don't wanna do anything.

[@JWStreeter]

Yup, this is why the concept of a "hustle" or "grind" is cancer imo. And results-focused, hard work in general. It's simply not sustainable or practical. It's all about working smart - in a way that's practical and long-term. There's a time and a place for working as hard as you can to maximize short-term productivity and results, but only in special circumstances.

[@codinginflow]

@@JWStreeter Yea I learned this the hard way, through years of highs and subsequent crashes. Ironically, I wasted more time this way than if I had just worked at a more sustainable pace with more breaks. I think consistency is the only thing that really matters.

[@karolobiedzinski8421]

I've been struggling with the same exact thing, glad I'm not the only one lol you found anyway to combat it? Or just use em as a rest day?

[@codinginflow]

@@karolobiedzinski8421 I didn't really find a way to handle this better because I quickly feel guilty for not doing enough. The problem is, when I have such a bad day, it feels like it's never going to get better again. This makes it hard to just call it a rest day.

[@karolobiedzinski8421]

@@codinginflow It's like I'm reading an autobiography.. I'm getting use to listening whats going on internally and not feeling guilty for taking breaks when It literally feels like I rather die than keep going, that hard part seems to be of balancing of knowing when I should actually take a break or when I'm just being lazy, can never figure out which is which, which is probably where the guilt comes from

[@sdterv]

I am a 68 year old female. I was diagnosed with Parkinson's Disease in July 2022. My complaint of small writing got my family doctor's attention. I have stiffness and balance issues. I went to two different neurologists who had no information on something else other than sinemet. Its side effects compared to benefits are not worth taking! I am researching and embracing vitamins and minerals. That, and movement/balance PT has improved my quality of life. Not much info out there on dopamine and Parkinson's depletion of dopamine. Your info has given me a direction for research. Thank you for this (and other podcasts). Your examples are relevant and easy to understand. Brilliant.

[@nathaliemagdalena6743]

I really believe this and the interview with David Goggins are the Huberman Lab's best videos, and I've seen hundreds of his videos...every second of it is a treasure. Thank you!!!

[@Overthunk.]

Hey Nathalie! We love Dr. Huberman's videos just the same and make shorts animations based on his findings. Would love for you to tell us what you think =)

[@nathaliemagdalena6743]

@@Overthunk. hey! Where can I find that??

[@enjoythebliss3852]

Thank you so much; this podcast has changed my life. I am a fifty-five-year-old woman who has been struggling with Parkinson's for over four years. Even though I've read and studied everything available on the subject, nothing has been as helpful as your podcast. I live in France and would love to see your work translated into French so I can share it. God bless you and your work!

[@Lucasvoz]

Everything you said today confirms many of my own experimentations with pleasure and dopamine. You will truly experience life the most if you don’t overindulge in the high dopamine behavior, also learning how to enjoy the process instead of the reward, and lastly to not expect a reward every time you work for it. Amazing, insightful, and so informative. You’re the best Andrew!

[@advocate1563]

Grest advice. Giving up my vices has led to less excitrement (highs and lows) but much great peacr of.mind (flow). I lool back at my behaviour and realise I was incredibly self destructive, but can now see that much of that was dopa related.

[@Lucasvoz]

same story here! glad you feel so good now:)

[@marselshtylla]

i wanted to leave a very important message here to myself i had given up from trying to quit my addiction after failing for years of thinking and working and trying everything i could to stop.i can't even say what it is because i am embarrassed 17 years later and 2hours of a legendary podcast i today on 17th of June saturday 2023 8:43pm i have managed to control my brain for an entire week with nothing but willpower and i feel i can never fail i will continue to update andrew thank you for blessing our lives with your knowledge

[@MiguelEvolutionz]

👏

[@dmingod999]

How is it going? What strategy worked for you?

[@Iron_Willed]

How is it going bro. Keep on putting a fight.

[@marselshtylla]

i just cleared the thoughts whenever i would get even the slightest desire i would be like to myself remember how low it feels after and how long that low stays yea i prefer this unlimited long lasting high and just allways do stuff dont be sitting home doing nothing go out run work create something allways do so much that you feel ready to pass out and then just go sleep and do it again tomorrow this is a shortcut towards becoming a legend i am sorry but from me there will be no more updates i will be focusing on creating an online business and currently learning more about more fields good luck all

[@meltygear5955]

"nothing but willpower" is setting yourself for fail. You need strats. You don't just (for example) sit in front of a chocolate cake to try how hard you can resist it with sheer will. You just don't buy the cake.

[@user-jm2ct8cw2j]

Your the best, much appreciated for explaining us for 2 hours. To watch something for 2 hours feels like it’s too long but with patience you explained us for 2 hours. Thank you 😊

[@heatison11]

I experienced alot of what he's describing when I went through army basic training in 2010, after about 3 weeks us guys routinely started singing our favorite songs because of how much we missed just basic things like music, at week 15 we were allowed to order pizza and relax for the first time in what seemed like eternity, I'll never forget that feeling

[@Dam3k]

Going through a dip in motivation, this video was EXTREMELY helpful. For some reason, it feels like when you start understanding things about your brain and body at an intellectual level something clicks in you... Something that somehow helps...!

[@robertozotti2235]

Same for me buddy 💪

[@bimald3v]

This is so true! This is exactly how I felt!!

[@Aashu24ahuja]

it feels like when you start understanding things about your brain and body at an intellectual level something clicks in you - May be this is also releasing dopamine ;-)

[@Dam3k]

@@Aashu24ahuja Very true

[@calebbreeland6439]

That's why they say "knowledge is power."

[@juandavidobando2662]

I've had a dopamine release, listening this. It's a priceless podcast. Thank you so much for doing it.

[@AY-eq8rw]

Now be careful to spike the dopamine than required. By not adding other stimulants and taking a break after the podcast to reset the base line levels. Writing summary of the points and moving onto some boring task might help too. ( :P me trying to be dopamine engineer here)

[@ivanyegoh3420]

@@AY-eq8rw nice one mate

[@ardypangihutan3653]

I just got dopamine release just by learning valuable information like this.

[@stevetakacs654]

Hello Dr. Hurberman. I've suffered from depression and anxiety for 10 years. Lots of ups and downs. I have watched some of your cold water therapy. Been FF going cold showers twice a day. I started with cool water eventually working into just cold showers. I'm slowly moving to cold baths. I've been working on other videos too. You have helped me learn to even out my moods . Thank you so much.

[@killroy8146]

As someone who was using vvyanse, weed, nicotine, caffeine, and seratonin/dopamine meds daily to overcome my absolute loss of motivation and severe depression, this is genuinely life changing even just from a mindset perspective. Even at the absolute minimum that I've taken away from this video, I feel renewed knowing that I have more control over my drive than I ever thought. This has given me hope, and I thank you.

[@markrung8051]

I've not watched this yet but you sound similar to me. Looking forward to watching.

[@3ulogy]

I wish it did the same to me, I was just getting annoyed with all the technical crap throughout the entire episode. Knowing the intricacies of how neurons work is just not applicable. Found myself fast forwarding 90% of the episode. Got more from the comment sections than anything.

[@PushYourEdge]

love this comment 🙏🏽

[@jennifercarleton7550]

@@3ulogy I actually enjoyed the scientific info, although I can certainly understand it is not for everyone.

[@richcox]

I spent most of my research career studying dopamine and the N-S pathway as an in vivo electrophysiologist. This is an excellent and easily digested overview/review. I'm currently retired from science, but am doing literature reviews on the neuroscience of "creativity"

[@marquellbrackett8671]

Do you have any types of sources for where the creativity research from you or others is?

[@poorboistudios]

"Enjoy the suck"- Uncle Sam. A decade after hearing that, I realize it relates to dopamine modulation through the focused intent to try and enjoy anything one feels that they want to do, or must do, in life.

[@abdolhamedsharef2924]

Professor Andrew is like a book you have to read more than once ❤

[@thechildofprophecy9135]

If i copy paste the video transcript that'll be a million dollar book.

[@Oldysrv]

He is not a professor.hes just a podcaster

[@cyrusadamrevilla3851]

I'm not exaggerating when I say this: This video will change my life forever. And I will never be able to thank you enough for it.

[@storyzen6834]

How is it going

[@abdurrhmanaliliban]

Listening to those who have reached the pinnacle of their fields is both humbling and inspiring.

[@nyuki187]

This video could not have found me at a better time in my life, this is invaluable. Thank yo very much Andrew.

[@BoloBouncer]

I was reading Unbroken, the story about the U.S. military airmen who were stranded in the Pacific during WWII. There's a short passage about when they drifted into the doldrums after weeks on the raft. Instead of writing, "We were in a torturous hell, starving and not going anywhere," he describes it as one of the most peaceful serene moments of his entire life. I can't help but think at that point they had been so bereft of any dopamine-rewarding anything for so long that they were perfectly honed to appreciate the extreme stillness of that moment.

[@carolhopetyler2178]

Yes

[@vidalskyociosen3326]

The body including the brain will do anything to survive , in some instances it will shut your conscious mind , next thing you know woke in hospital stable, sometimes the body is much better without you.

[@napozayac8897]

Zamp!

[@peterbandsholm8853]

I have misused pleasures throughout my life, without knowing that it could inflict this damage to my reward pathway. Thank you Andrew, this is godsent

[@rubengarcia9655]

Same for me. I always wondered why Sundays were crappy for me. I thought it was because I had to go to work on Monday’s. But now I realized it was all the dopamine highs I had Saturday night

[@sierrablanco5672]

Same and working with children.. reward is used often. Now im questioning

[@caninecuts]

Peter, I have spent 60+ years destroying my motivation. 30+ years on ADD drugs were the most vicious. But this podcast will help me go forward. I think there are a LOT of us out here in the same boat

[@ritheshp1170]

Hats off to You!!! This was my first podcast I watched and I have documented every single thing you have said. I have also realised the tools you suggested actually help as I have applied them before. If anyone follows your suggestions, they will improve their life in this addicted world. Thanks Dr Andrew Huberman!!

[@vijoywinson9246]

Have you ever studied a human who is a devot catholic on regarding dopamine. As I myself is a practising catholic i often felt the daily time I spend with God by prayer gives me a sense of dopamine as you mentioned. I do have other dopamine hits ,which everyone have or which is very common like a coffe ,working out or chocolates; which tend to go away after a while.. but with Jesus ,I felt I am getting adequate level of dopamine. I felt that because i was not religious or practising in between for a while and came back..I got that sense of dopamine or happiness back in track..eventhough i tried my other ways, which doesnt have a good effects on me. I would like to see if there are some research done o this way ?? Nice lecture.. learned a lot.thanks

[@bricktamland7964]

This episode is far better than any other motivational video I came across on KZbin. Keep doing what you're doing Dr. Huberman. You're positively impacting many people's lives with this content.

[@kaveendayananda8063]

Indeed! This is next level stuff.

[@PetrollCoaching]

Every time I watch a Huberman video, I feel like I just got an entire semester of knowledge in 2- 3 hours! He is a national treasure!

[@vijaysharma6677]

Hi Dr Huberman, Excellent video as usual. I am from India and we have been taught since ages to take a cold bath in the morning esp in the river ( if it is near you) and though I tried hard to understand the rational behind it i couldnt . thanks to you for making it clear. the more I watch and study your podcasts , the more i admire our ancient sages as they praticed and taught , what scientiests are doing now. Getting up 4 in the morning , having a ice-cold bath in the river, then having light food in the brakefast , having dinner before sunset to sleeping at 8 in the night made them amazingly healthy and sane. I am trying to adopt some practices in my life and started to take a cold bath slowly and gradually . thanking you once again for sharing these insights . Love and respect from India.

[@nguyenducanh7082]

What an astonishing job, Andrew! Having relied on motivation before taking on challenges throughout my entire life, I now realize that I can proactively enhance my quality of life by applying science-backed protocols from your videos. This further reinforces my strong belief in science. I couldn't be more grateful for your work!

[@sulaninetumila]

I am a medical student. Recently I feel so miserable in my life for no reason. I don't enjoy the things I did before. I thought that there is something wrong with me. But now I can understand that low level of dopamine level could be the reason for that. Thank you so much for all these informations. I am going to improve myself better.❤

[@UncleHam1337]

"Is the reason..." - Fix that with "Could be the reason.." and your better life COULD start right after reading this :)

[@elizabethfletcher1487]

How are you doing now? I would hate to think that you are still in that hole. You have chosen a difficult field, and a great deal of that difficulty is artificial, induced by whatever insanity seems to provoke the people who direct the training. Hang in there, sleep whenever you can, no alcohol, good wholesome food. Good luck.

[@angefallen2024]

Good lucky bro, I hope you can reach your goal and improve your mental health!

[@iifridgeii9933]

wow, i'm currently doing a bachelors in psychology at uni and I feel like I've just sat down for a zoom lecture with a top quality professor. very good and very appreciated

[@elizabethmolnar4643]

Watch Robert Saplosky 's lecture on Dopamine. He has a couple lectues on Dopamine. But - Anticipation is the key. Outstanding lecture. Please give this lecture your time.

[@iifridgeii9933]

@@elizabethmolnar4643 Thank you, will do :)

[@stevenbalogh6462]

They teach you outdated and useless information in colleges nowadays. They also indoctrinate you on beliefs not based in fact, aka wokeism. Its better to save your time and money and not go to college. College kids that are indoctrinated are causing the destruction of our society and values.

[@iifridgeii9933]

@@stevenbalogh6462 not sure if its exactly the same scenario in England where i go to uni… Plus every individual has the capability to think for themselves and decide what to agree and disagree with. Like Aristotle said, a good mind can analyse books/information without being consumed by it. Most things aren’t as white or black as they may seem, even “wokeism”.

[@stevenbalogh6462]

@@iifridgeii9933 most of the population doesnt have what Aristotle described, that's what the elites take advantage of.

[@user-xj8vl5rq3w]

Thank you so much ❤ You are literally saved my life and existence. I was struggling with ADHD whole my life, and fortunately to youtube algorithms I find your channel, where I can explore the ways how to improve the quality of my life. Thank you so much, Andrew! Absolutely amazing work!

[@JulesVermunt]

What tools or tips of this video did help you the most?

[@theboyfromhills]

first of all i would like to thank you for having a profound discussions on a dopamine system, the knowledge and findings you share with us is really helpful for the community. God Bless You , Sir

[@shelleyscott7266]

What makes me cringe is that this information is not taught in school. I am 48 years old and am only learning this. Absolutely mind-blowing. Very well explained. CHEERS Andrew!

[@antonismetallidis5695]

How many 10 year olds would grasp these concepts ?

[@savioncohen8136]

@@antonismetallidis5695 idk about 10 years old, but I would’ve loved to have gained some of this knowledge in high school

[@adityavikramrajawat]

He teaches in school in case you missed that

[@boogerbust619]

Tbh, this is probably too much for the teachers

[@justine2589]

This is graduate level neuroscience. It is taught in grad school.

[@ROFLance]

I did 22:2 intermittent fasting for 4 months from 2/9/21 through 6/9/21, and not only did I drop from 230 to 150 lbs, but my personality has changed drastically. I went from being in a depressing mental fog with no energy to exercising daily and feeling incredibly motivated and happier than I ever thought possible. I now see that it was due to dopamine release from my effort. What an incredible video. Thank you so much for this invaluable tool that you've given to the world. I wish I was rich so I could send you money, but all I've got is love, so take it! ❤❤❤

[@gaberoyalll]

Awesome story! Thanks for sharing with us

[@aqueelon]

Andrew, thank you ever so much. Education and awareness is the tools that can make humanity thrive and the lack of those might lead us back to the dark age of superstitious and emotional decision making selves that we, by all means, should get over with and make that leap of faith into the only possible state of existence: then self-recognition and acceptance of ourselves as we were created!

[@elseverehmedli8819]

One of the most precious channels on KZbin, I can't believe it and really regret that I didn't discover this channel much earlier

[@Chasdt20]

"Try removing multiple sources if dopamine release...from activities that you want to enjoy." That was awesome, thank you for the hard work you put into these podcasts. They are so helpful.

[@fyodortitarenko9177]

Dr. Huberman, basing on the several recent episodes, I've come to an understanding that if one would eliminate activities that make the brain release high portions of dopamine for 40 days and more, dopamine receptors would eventually start to respond to lower portions of dopamine. Then, later on, previously boring activities would start to be perceived by the brain as interesting ones and they would become higher dopamine activities, therefore, mitigating ADHD symptoms and making focusing on them easier. In other words to be able to love doing hard things that are good in the long perspective, one must get rid of short-term gratification activities. Is this correct? EDIT. I wrote this comment as soon I saw the video released hoping my question would be noticed, because as far as I've noticed Dr. Huberman answers questions in the comment section on the day of release of a video, so I did not watch the video then. The answer to my question, and other similar questions below, is at 1:05:32 .I hope it helps. Keep up the search for knowledge and do not give up, you all. Thanks to Dr. Huberman.

[@michaelmcdonagh292]

Just in case he doesn't respond, I think you are pretty much right. I only know due to extensive research on porn addiction. The dopamine release from watching porn can be as addictive and powerful as cocaine (for example). There is plenty of research into the impact abstaining from porn has on the brain (from those that watch it regularly). Most individuals tend to go through a 'flatline' where the body is screaming out for that dopamine release and the individual goes through a 'depressive period'. However, beyond the 60-90 day mark, they begin to enjoy activities that didn't interest them as much, are much happier, more productive etc. Just giving themselves that break from the overpowering dopamine feast that is porn seems to almost reset the brain. I find it fascinating.

[@theyeking7023]

Lol not just porn even masturbation

[@schijtaccount1]

I tried this but went too hard.. crashed and burned and fell in all old paterns and ADHD kicked in to the max after...

[@mmafighterdp3263]

I understood it this way as well but would be highly interested in Professor Hubermans answer.

[@michaelmcdonagh292]

@@theyeking7023 a real deadly combination for sure.

[@ms.sassyone]

Wow this is so intriguing, educational & eye opening. I'm so glad I found this...I just had surgery & had surgery complications afterwards. I went to the e.r. they injected me with compazine for the nausea I was having. I began to feel the worst feeling after they injected me with that. I began having uncontrollable body movements, agitation for 3 days straight after. I couldn't sit still, barely sleep & eat. Now days after I feel so sad & depressed I've been crying over everything. It's been the worst! Compazine is a antipsychotic drug but they use for nausea too. I also consume Yerba Mate everyday every since I've cut coffee & soda out of my diet several years ago. To learn this is negatively impacting my dopamine levels is crazy when I thought the opposite.

[@fox_english]

I can listen to him forever 😌 As a teacher, I found a lot of useful information. Completely clear and precise, capturing important nuances as much as possible, considering how complex and multifaceted neuroscience is. Helps to systematize existing knowledge. And this sweat voice... makes it more enjoyable 👍

[@DoctorErtan]

Professor, I love the way you explain things in a way that both people who are really interested in neurobiology and the people who are not can understand. I am grateful for the effort, time and energy (probably tears too) you put into this podcast. World needs more people like you.

[@kelvincastro1277]

La

[@nicolas_sch]

👏🏼

[@melbbb5673]

I had always felt that drop after a high of accomplishing - I could never understand it before this. Below baseline makes so much sense - thank you!

[@adwait8718]

For me this was the first video of Dr. Huberman here. It is really amazing and I am wondering why such scientific knowledge is not imparted in the school curriculum.If this is given to minors at appropriate time then many types of crimes and suicide attempts can be reduced. Many thanks to Dr. Andrew Huberman for this video❤

[@distantraven2566]

I'll be coming back to this one in a week or 2. Thank you Dr. Huberman.

[@vintage4000]

It's your belated happy Birthday Dr. Andrew you are the best. You helped so many people including me. I feel my dopamine spiked when I saw you have a new episode.❤❤❤

[@not_elm0]

HBD Dr Hu 🎂🥳

[@tubo1812]

What is the birthday date?

[@TheMentalLevel]

That's a good way of putting it.

[@sweetieturner3377]

Happy birthday !!! ❤

[@Burtonracingboard6]

Don't spike his dopamine by wishing him a "happy birthday" just say "it's your belated birthday good job"

[@jopo7996]

The notification for this podcast spiked my dopamine.

[@swarajkundu5593]

How many of you, at some level, already knew some of things from experience and after watching this video got the scientific validation?

[@luiscastrodeoliveiravicent9493]

I am fromAfrica and I enjoy and learn a lot with Dr. Huberman' s podcast. Thank you!!!

[@missyethio1398]

WOW! What we traditionally refer to as the highs and lows of everyday life, and the why of the swinging feelings, explained scientifically. Dr. Huberman, you are a gem to our generation!! I LOVE your podcasts! Thank you very much!!!

[@annetteyoutube742]

Great extrapolation of this presentation 👏

[@sajjadayobi688]

I'm 21 in my poor country studying artificial intelligence. I deeply appreciate people like Dr. Huberman for educating people like me and giving us a chance to learn how to live better and healthier with zero cost. Keep up the good work, Sir.

[@Kaeso97]

I love you man we are all gonna make it

[@badgerlife9541]

What country is that? I sincerely hope you can improve the people around you, even if not your country. Hang in there.

[@Kaeso97]

@@badgerlife9541 don’t worry he has internet in a « poor country » so he’s at least from middle-class if not bourgeoisie and maybe got caught up in the victimhood mentality like a lot of us out there

[@sajjadayobi688]

@@Kaeso97 In my opinion a poor country is where most of the people aren't educated due to money problems and don't have enough spare time to learn on their own.

[@sajjadayobi688]

@@badgerlife9541 thanks dude, that's indeed my goal to improve and love myself and other people around me