Aplastic Anemia - All you need to know - Definition, Causes, Symptoms, Diagnosis & Treatment

[@MedicosisPerfectionalis]

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[@Xingaboo]

Phenytoin

[@MedicosisPerfectionalis]

Yes!

[@aditimandal1638]

Phenytoin

[@dr.shrimati8596]

😊😊😊😊😊😊

[@hansanisapna]

Thank you so much for your incredible work. I totally depended on these videos for years as a medical student. Finally graduated and wanted you to know how many people are actually learning from you. u have amazing teaching skills, excellent presentation, good humor, btw speed of narration is totally fine, so much content within a short period of time is just what’s needed. Pls keep up the good work. Love from Sri Lanka.

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"Idiopathic" = "Pathology of the idiots or better said we are the idiots that we don't know what causes them." - This is the reason for why I am watching these videos.

[@chaimafaraji8921]

i have my finals in a few days, and i have just discovered your channel :( , but i can't stop watching. thank u so much for ur efforts!

[@MedicosisPerfectionalis]

You're very welcome!

[@AbdulMaalikk]

Saaammmeee

[@kingwhyte4815]

@@AbdulMaalikk what are u studying?

[@ذکریسلمانغازي]

Me too 😅

[@donnaprosperini2557]

Thank you so much for your videos, I finished medical school 22 years ago, and I've been out of medicine for seven years now, I'm catching up with your videos, to get back to it!!! Now children are old enough!!!

[@johntom2362]

The answer to the question is D. Phenytoin Thanks for the tutorial. It really helped

[@hafsaK-life]

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[@MedicosisPerfectionalis]

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[@crazyfangirlproductions6426]

This is a great video my sister has a aplastic anemia and we are getting ready to start the bone marrow transplant treatment for her

[@vikrampatil2245]

How was the treatment? How's your sister? Want to know everything about it

[@pravinjadgeri6980]

Hi I had a plastic anemia issue. But right now I have cure from it yes I have take allopathy(chemical) medicines. But later on I have shifted to ayurvedic medicine( natural medicine). After taking ayurvedic I have been healed/cured from it. completely Yes it can cured. And healed.

[@Pr0ph3cy-k5z]

​@@pravinjadgeri6980Ayurvedic is great, but no one is going for the scam whatsapp number bs.

[@jebaanika8805]

​@@pravinjadgeri6980pls apu help me. What us the treatment. And how i conduct you?

[@wassimabdou7649]

Bless her

[@harishchandra7362]

I am really thankful to you for such a nice presentation in a very simple way.All of my students are now become fan of your lectures.The way you deliver it ,that's the key,you mostly uses such a nice words,that are catchy and everyone can remember that. Thank you very much and keep doing this noble job. GOD bless you.

[@MedicosisPerfectionalis]

Thanks a lot for this awesome comment...It touches my heart ❤️...Thanks a million! God bless you too!

[@jbizzle4922]

not even a medical student, but these are the most comprehensive videos I've watched.

[@MedicosisPerfectionalis]

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After 3 days I have an exam, from 7pm till 10am, I cannot stop watching... thank youuuuuuu!

[@MedicosisPerfectionalis]

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I'm in fourth year , I remember u had only 30k subscribers when I was in early 2nd year , U have great quality lectures , One day u will be millionaire I promise 🥰

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[@yesplz-f7n]

now its 1.29M and I'm in 4th year (China)

[@invisiodisvy518]

This video is extremely concise and complete for a big topic of aplastic anemia. Came back here from reading harrison's. Contents can be confirmed as same. Thank you medicosis ❤

[@MedicosisPerfectionalis]

Glad it was helpful!

[@omerali2597]

Nice review of aplastic anemia! Just wanted to add that sometimes you can get a hypocellular MDS that looks similar to severe aplastic anemia. Usually cell morphology and cytogenetics will help you differentiate the two (hypocellular MDS you would expect more chromosomal abnormalities, aberrant megakaryocytes + megs will be small in appearance), however clinically they can look very similar. Thanks for the video!

[@MedicosisPerfectionalis]

Thanks for your comment!

[@life_happens_reviews]

@@MedicosisPerfectionalis thank you for this - i have this via my maternal great grandmother so it's hereditary in my case and may explain the issue with my menses not ceasing over the many decades from thirteen to recently at forty five years old severe with pcos and possibly endometriosis

[@erikaandrade6912]

I'm from Brazil and at this moment I'm studying hematology. Your videos are so good!! Congratulations! I will always follow your channel now

[@MedicosisPerfectionalis]

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Estamos juntos

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[@MedicosisPerfectionalis]

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[@dev72632]

Phenytoin . Lovely explanation

[@TheThomprc]

Presently diagnosed with Pancytopenia, awaiting further evaluation. Your presentation is the the best I've viewed and highly reccommend it. Thanks for composing this video.

[@quinn1781]

Your videos have provided me with more information than Dr’s have in my 22 years of living.

[@MedicosisPerfectionalis]

Wow 😯

[@drSJV]

Doctors give lectures in the universities or other events. Unfortunately at the reception there's no time for that

[@DanielCollins-ws5iu]

Great info and presentation. I am seeing a Hematologist tomorrow and this was very informative. Thank you.

[@MedicosisPerfectionalis]

You're very welcome! Thank you so much 😊

[@ecmobb8749]

Thank you AA patient. Recently diagnosed. This explains more than any doctor i have seen. Much love!!!

[@MedicosisPerfectionalis]

Thank you so much! I wish you the best of luck!

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Hello I have medicine contact me urgently my contact number Mine DP pic.message me in watsup

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Great lecture,I follow you're lecture from 3 years ,now I am 4th years MBBS students,all you're topic is conceptual ,and make a good sense abundle of thanks keep it up

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[@MedicosisPerfectionalis]

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मैं भारत 🇮🇳 से हूं, मुझे आपका वीडियो देखना बहुत पसंद है, बहुत-बहुत धन्यवाद! ❤😊

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[@MedicosisPerfectionalis]

My pleasure 😇 Medicine is awesome 👏 Learning is fun!

[@bibihanifa874]

Great effort! CLEAR+SUMMARIZED yet detailed! God Bless, as u r doing a great help to us all..

[@MedicosisPerfectionalis]

Thank you so much 😊

[@yamitsh95]

The Answer for the Question at 18:53 is Phenytoin, a Sodium channel blocker.

[@LeahHan-ud5bd]

Thank you so much. You cleared all of my concepts.🎉

[@MedicosisPerfectionalis]

Glad it helped!

[@juni_vlogzzz]

thank you sm for this ive been in the hospital for a month so hopefuly i can get a bone marrow transplant thank you

[@harshitbansal5983]

Sir, your videos are really so good. It helped me a lot. Now, I'm a big fan. Thank you very much to provide such great medical videos for free.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@francinebarr1204]

If I had you as a teacher back in the 50’s & 60’s. I would be a doctor today 😊

[@MedicosisPerfectionalis]

😊😊😊 Thank you!

[@elenaprk5628]

Eltrombopag has been added to standard immunosupression for AA.

[@Zckwarriar2009zi]

Thank you so much for such a complete video. 🙏 👏 👏

[@MedicosisPerfectionalis]

My pleasure 😇

[@sanashaikh1442]

I'm big fan of u , hope I will meet u one day from india

[@shreyark9009]

More love and support from India🌻

[@MedicosisPerfectionalis]

Thank you so much 😊

[@JBsquirrel]

Thanks, helped out with my presentation on TERT gene mutations causing aplastic anaemia.

[@MedicosisPerfectionalis]

I am glad to hear that! Thanks for watching!

[@hamdiabdi686]

You are realy great teacher Thanks alot my lecturer

[@ahmedabdirahman9918]

Phenytoin.... and thanks for ur time Dr.

[@arash_shahab7]

Phenytoin, thanks for your explanation and efforts ❤

[@MedicosisPerfectionalis]

My pleasure!

[@abukeabdela4928]

I am binging ur videos ...much appreciated ..why don't we consider aplastic anemia as one of the differential for dry tap as mylofibrosis or mylophtisis since it causes hypocellular bone marrow

[@Nora-dx9cy]

And you WILL NEVER FAIL US

[@MedicosisPerfectionalis]

Thank you!

[@hdey8653]

11 years a go when I was 10,I was diagnosed with aplastic anemia, Now,no sign of it,but it has brought PNH

[@drtuber4435]

Phenytoin.... Excellent and capsulated class

[@Muskaan__12345]

Fetal anomaly caused by phenytoin is Fetal Hydantoin Syndrome And Lithium causes Ebstein's anomaly (atrialisation of ventricles)

[@marinaelnesr2061]

wow , you are amazing , you makes me enjoy medicine , thank you very much 💞

[@MedicosisPerfectionalis]

Thank you 😊

[@Mazzawak]

Great video as always! I should note that Parvo-B19 very rarely causes Aplastic Anemia and is more often with Pure Red Cell Aplasia

[@MedicosisPerfectionalis]

True

[@dheerajduggi8069]

Hello I have medicine contact me urgently my contact number Mine DP pic.message me in watsup

[@alinaswechitimbwa2607]

Lovely presentation Answer is phenytoin

[@MedicosisPerfectionalis]

Thank you!

[@drSJV]

Such an excellent video again. Thank you 🤍☕☕

[@MedicosisPerfectionalis]

My pleasure 😇

[@dr.ahmdooz]

i need to know .... when I'll have like your science ... please tell us in other video about you and your studying and advice you can give it to us 💕💕💕 i love you from whole my heart ❤

[@MedicosisPerfectionalis]

Thank you so much 😊 I think I should talk about in the future

[@dr.ahmdooz]

@@MedicosisPerfectionalis i will waiting

[@MedicosisPerfectionalis]

Thank you 🙏

[@tj7683]

Answer- Phenytoin

[@shushree1772]

slow but very clear thank you

[@Am-yo4hx]

great explaination I hope you add video about Diamond Blackfan anemia

[@mjk9152]

When I see the disease in the book, I feel disturbed by the many details. Then I search on KZbin and find a video for you. I am very happy, thank you very much from the heart💙💙💙💙💙💙💙💙✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨✨💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙💙🙏🙏🙏🙏🙏🙏🙏🙏

[@nairdarumani5450]

Today i have to learn aplastic anemia for my tomorrow hematology class and this video was absolutely amazing and very helpfull. I got only one question.. I have read that the hypothesis that aplastic anemia is a state before mielodisplasic syndrome is not so strongly approved according to the new findings in the genome. I dont know how true this is but i read some good arguements

[@MedicosisPerfectionalis]

Thanks for your comment! You are absolutely welcome! As for that theory, I am not sure, to be honest!

[@mahbubamaria1742]

I have a question. If there is anemia why there is no hepatosplenomegaly (for compensating anemia) Why there is no lymphadenopathy(as there will be increased infection) Can you please answer these. I can't find any satisfactory answer.

[@fatemazoher3924]

thank you for the helpful video but the KZbin ads make it very difficult with the constant interruption. Any way you can prevent that ?

[@Medical_Sciences]

Fantastic explanation

[@MedicosisPerfectionalis]

Thank you so much 😊

[@dr.vikashkumarupadhyay3450]

Phenytoin... Nice one!!

[@yasoyoshikage]

I am trying to understand. It's so much fun. Thank you so so so much.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@asaku6248]

So it’s been a week and I’m living In hematology playlist 😂❤ I’m really having fun , I didn’t use to like hematology but now hematology really makes sense with your awesome explanation 😭💕🫧 And what makes me proud that all this wonderful work from an Arabian , I’ve told my whole family about that! , even my friends at medical school, with respect to everyone but really medicosis was my first line in every hard matter so that’s makes me more proud thank you sir , really Thanks alot for your hard and exquisite work ! Wish you life full of health and happiness 🤲🏻🤍

[@radioaktivguy8789]

answer:phenytoin coz anti convulsive so im guessing sumthing to do with sodium methotraxate :immunosupressant dmard nifedipine : ca channel blocker aspirin :antiplatelet atorvastatin - statin for cholesterol control

[@عبقالزهور-ب8غ]

I like you're special and simple way please keep going ❤

[@35jayaprakash60]

Phenytoin is the answer...causing hirsutism,gingival hyperplasia

[@drinkspartypack]

I go to the same school Eric Connor went to, he is one of the eight people in the world who has had aplastic anemea.

[@MedicosisPerfectionalis]

Aplastic anemia patients are more than eight.

[@drinkspartypack]

@@MedicosisPerfectionalis sorry, that is my mistake, my gym teacher told me that there are eight, but apparently that is incorrect.

[@MedicosisPerfectionalis]

No worries...There are way more than that. Thanks for being honest and open-minded...I really appreciate that :)

[@medicine4775]

Amazing video thank you so much !!

[@ali53240]

thank you for the explanation

[@MedicosisPerfectionalis]

My pleasure 😇

[@KenzyFarid]

Thank you so much, you are the best!

[@khamikos1]

perfect presentation very helpfuland easily comprehensive/thanks deeply

[@MedicosisPerfectionalis]

My pleasure! Please share with your friends! Thanks a million! 😃

[@yousefrezaei2979]

Beautiful explanation...well done

[@MohamedHassan-zp5ml]

Such a great explanation WoooW❤️

[@The_foot_of_the_Cross]

Really awesome video ... excellent !!!

[@MedicosisPerfectionalis]

Thanks 🙏

[@aiyu5793]

The answer is C) Nifedipine

[@sirbey9608]

Wow my Dr told me yesterday I was low in iron and need to take iron with orange juice she never went into this could be the cause of my headache which I think is nerve pain .thanks for the info

[@MedicosisPerfectionalis]

My pleasure...I wish you speedy recovery...Keep me updated...Good luck 👍

[@dreamprojectformedicos2313]

Phenytoin..Option D is answer.

[@mirmuteeb7818]

phenytoin... awesome explanation

[@suryakantdongre3969]

Thank you sir

[@Dr-sr4nl]

Of course "Phenytoin "

[@hdey8653]

I haven't had bonemarrow transplant

[@idkwhattonameit8359]

the answer is Phenytoin

[@MedicosisPerfectionalis]

Yes!

[@alshbah.e320]

What abour a megaloblastic anemia does has pancytopenia?!

[@srivignesh9680]

What is solution for continuously wait loss and Hemoglobin level is (10) vitamin B12 is (0) and iron vitamin is (0) Age 57 please anybody tell me the solution for this problem

[@وليدالعليي-ه3ق]

thank you for your a nice explanation

[@MedicosisPerfectionalis]

It gives me great pleasure! You’re always welcome!

[@michellebierman5]

I'm thinking I was diagnosed wrong. They said I had leukemia but it came back. But I was on nefdipine, And ani seizure meds for migraines. I was also diagnosed with thrombocytopenia, Meloydysplastic anemia. When they would give me iron transfusion my platelets would drop so low that I would need a platelets transfusion. Just didn't make sense to me. Please if anyone as an insight to what is happening. Please let me know because I have a appointment with a new oncologist/hemotologist next week.

[@mohammedsalahadin1680]

OMG what a video, many thanks 😭🌹❤️

[@MedicosisPerfectionalis]

Glad you enjoyed it!

[@dr_chiropractor]

Aplastic anemia with high MCV but normocytic?? I don’t understand or you made a mistake at the intro

[@medicinemadeeasy8235]

Informative + fun, thanks man!

[@MedicosisPerfectionalis]

My pleasure 😇

[@alimobarak4821]

the answer is D)Phenytoin

[@rockycycle2682]

Another great Video, Thanks! Phenytoin

[@al21l51]

So it is low WBC and when blood is diagnosed they should show low in number. But again person can show leukemia. In other words, what will the WBC count be in acute myeloid leukemia and pancytopenia?

[@gamerberry2451]

Good day Sir, so I have a speculation as well as to why MCV is high is aplastic anemia.I’d love to know your thoughts. If MCV= Hematocrit(ht)/[RBC] This would mean that a decrease in [RBC] or increase in Ht should give high values of MCV right? We also know that in aplastic anemia, while Ht might remain the same (since all the other hématopoïetic cells are also affected), [RBC] is definitely low, hence giving high MCV values. Just a speculation, please correct me if I’m wrong😊.Thank you.

[@gerryadams2212]

MCV is also calculated via forward light scatter in flow cytometry. This gives each cell a direct reading of size

[@banaalani7216]

Thanks a lot! This is very very very helpful

[@MedicosisPerfectionalis]

My pleasure 😇

[@daisychi1111]

Ans : phenytoin

[@Bakbskshx]

i've applastic anemia. age:20years my doctor gave me horse atg with cyclosporine on 8thjanuary,2018.I'm also taking tab.eltrombopag 25mg but my platelet&hemoglobin count is not increasing.Last cbc report is below: HG-10.5,PL-34000,wbc-5.34 my hla type match is 10/9%. Now what can i do??? Please reply

[@maeb.6912]

Azmeer Hossan Joy I also have it for 3 years now 3 months ago I got a bone marrow transplant and I’m getting better

[@emiovy9594]

i have aplastic anemia too. i was given horse and rabbit ATG and i'm now in remission. i hope you the best of luck!

[@way2happiness400]

kzbin.info/www/bejne/bnW4mGyIpMh8n9E

[@mobrennanmcconnell7215]

My daughter starts ATG today. Praying it works for her with little side effects.

[@13litzkrieg65]

Got diagnosed last month with aplastic anemia, taking promacta, steroids and cyclosporine for 3 weeks now, waiting on chemo and stem cell transplant. The hardest part for me right now is dizziness and fatigue wish me luck, Im glad you all feel better , God Bless you.

[@analuisamartinez4597]

I was diagnosed with aplastic anemia with low rbc, low hgb, low hct, high MCV, but high reticulocytes, if bone marrow is not producing enough cells, why is reticulocyte count higher than normal? (Bone marrow cellularity is at 5-10%)

[@mustafacabdisalaan7306]

may b u had MDS[myelodysplastic syndrome has all you listed including hypercellular bone marrow]

[@elijahokoronkwo8610]

Could be relative reticulocyte count cuz its a percentage of whole blood. If it decreaces less than hct decreases then it’ll appear to increase. Theres a formula to get the adjusted retiuclocyte count in his earlier videos

[@eddieaguilar6737]

I have a question for you. What if the the patient is producing RETICULOCYTES?

[@MedicosisPerfectionalis]

I don’t understand the question...Can you explain more, please?

[@venukasharma1991]

please clear one of my queries not related to this video ....i.e why are neutrophils high in pregnancy state

[@MedicosisPerfectionalis]

Pregnancy is a physiological “stress” state.

[@iremsenabulbul5753]

you are a life saver!

[@MedicosisPerfectionalis]

Thank you 🙏

[@RR-we7iz]

Very very thanks for your nice explanation 🤓

[@MedicosisPerfectionalis]

You’re absolutely welcome! 👍