Are LMHR at a Higher Risk of Heart Disease? - David Diamond -

[@colinvankeith4814]

Recent LDL 584. I’m 75, carnivore now and low carb for 10 years. Never been this healthy. My regret is not having this kind of knowledge several decades ago. I have much gratitude for this community!

[@LowCarbLowDrama]

Cholesterol is part of your innate protective system for your health, and, of course, they would want to lower it.

[@firelight-vitality]

@@LowCarbLowDrama I like your handle - Low Carb, Low Drama. Carbs do overexcite the brain.

[@LowCarbLowDrama]

@climate-civilizations yep, I was naturally a low carber earlier in my life, but I started following mainstream "experts" dietary advice and ate high carbohydrate low animal fat whole foods with minimal ASF. That led me to multiple physical ailments and mental health issues. If you live by the food pyramid, you'll die by the food pyramid. Good Health 👍

[@myoung48281]

How long were you not carnivore, lol. Thank that.

[@LowCarbLowDrama]

@myoung48281 The real question should be, "Was your health mediocre prior to carnivore, and how much has it improved since?". There's always a reason why most people are in this carnivore health space.

[@firelight-vitality]

Prior to the widespread use of statins, which began in the late 1980s, the National Cholesterol Education Program (NCEP) defined high cholesterol as: Total cholesterol: 300 mg/dL or higher LDL (bad) cholesterol: 190 mg/dL or higher HDL (good) cholesterol: Less than 40 mg/dL in men, less than 50 mg/dL in women In 1993, the NCEP introduced the Adult Treatment Panel (ATP) III guidelines, which lowered the threshold for high cholesterol to: Total cholesterol: 240 mg/dL or higher LDL cholesterol: 160 mg/dL or higher HDL cholesterol: Less than 40 mg/dL in men, less than 50 mg/dL in women The ATP III guidelines also introduced the concept of "optimal" cholesterol levels, which were defined as: Total cholesterol: Less than 200 mg/dL LDL cholesterol: Less than 130 mg/dL HDL cholesterol: 60 mg/dL or higher In 2013, the American College of Cardiology (ACC) and the American Heart Association (AHA) released new guidelines, which further lowered the threshold for high cholesterol to: Total cholesterol: 190 mg/dL or higher LDL cholesterol: 130 mg/dL or higher HDL cholesterol: Less than 60 mg/dL in men, less than 50 mg/dL in women The ACC/AHA guidelines also introduced a new classification system, which categorizes cholesterol levels into four groups: Normal: Less than 160 mg/dL Borderline high: 160-189 mg/dL High: 190-239 mg/dL Very high: 240 mg/dL or higher Follow the money!

[@Malcolm-Achtman]

I've been aware of this "nonsense" but you have it summarized nicely here all in one place.

[@jobrown8146]

Thank you for posting this information. I was already aware of this but seeing it laid out like you have done is good. QUESTION: Did they give triglyceride numbers?

[@leetalbot7025]

Damn

[@barblacy619]

Those who do not learn from history are doomed.

[@ematise]

Thank you for this summary. Really an eye opener.

[@mark11145]

I am a LMHR. I have been carnivore for 2 years and have been following these scientists closely. I love how you now have the answers taped out and can succinctly explain even the results in past studies to demonstrate the truth. Thank you so much.

[@Spurgeon687]

This video is the best LDL presentation I have seen so far. Covers all the bases with regard to a common sense approach to LDL. I am 66 years old and I’m on a low carb no processed food diet and have an LDL-C of 150 all other metabolic markers are very good . My doctor is pushing for statins. I asked for a Lipoprotein Particle Profile NMR blood test but doctor refused. So I got my own and found out my Small LDL P count was low at 295. Went back to my doctor and she has no idea what that means. Thanks for educating people like me that know we are healthy but are being pressured by doctors to be put on statins.

[@jackiemoify]

From the UK here. The push for statin use is phenomenal just now. As a pharmacist in general practice I am seeing so many people being initiated on them This is by far the best analysis of the topic of high cholesterol that I have seen so far. So glad this came up in my feed Since going lo carb last year I have become a LMHR. I too have been badgered to go on a statin. I wish I had this information to share with the prescriber!!

[@mariapapadopoulou7368]

Greece here. I ve been terrorized by 4 doctors to take statins. I didn t and live since then in fear. They are criminals. I ve started to educate myself in matters of health, cause i don t trust doctors any more AT ALL. We pay though a lot of money to them here. Something must be done. What kind of "civilization" is this, when people have the impression that doctors play with their lives for money?

[@BeefNEggs057]

Glad to see the cholesterol fallacy getting taken down brick by corrupt brick. Keep your LDL high folks. Carnivore is how you live well. I don’t want to live forever. I just want my years to be healthy without dementia.

[@ucchi9829]

@@BeefNEggs057 cope

[@suprememasteroftheuniverse]

ucchi, "cope" 12 years old vegan, these people are already older than you will ever be. My grandparents are over 700 and past 100 years of age. "Cope", kid.

[@suprememasteroftheuniverse]

You're just a little girl angry because reality is showing that all your "good girl" effort on "healthy diet" is useless therefore you wish these people's ⚰️💀.

[@captainadams7569]

You meat eaters don’t have the discipline to eat healthy so you take the easy way out. I get it. Fruits and vegetables aren’t as tasty as a steak, or burger. I noticed these people who promote keto demonize carbohydrates as one and the same, which is not true. Complex carbs, fruits, vegetables, whole grains, beans, nuts, legumes, sweet potatoes etc don’t cause insulin or blood sugar issues. It’s the simple sugar carbs that causes blood sugar and triglycerides issues. cakes, pies, cookies crackers, white flour, white rice, pasta. The speaker not once made a distinction. Between complex carbs, and simple sugar carbs. I wonder why? He never once said ALL carbs. He’s promoting his keto diet book.

[@charlesincharge3404]

@@captainadams7569 You simply don't get it, and likely never will. I actually feel sorry for you, and hope someone shows you the light one day.

[@andredaedone7732]

My LDL is 541 but it has been high or supposedly very high for 45 years. My HDL is 80 and of course I am Carnivore and feel super great. I am 69.

[@nuryener9188]

What is yr blood type?

[@andredaedone7732]

@@nuryener9188 I am just an O+ kind of guy.

[@nuryener9188]

@@andredaedone7732 maybe that is why you can tolerate such high c. Dr.dadamo says o types r meat guys

[@thehassanhashemi]

Make sure you do not feel too great as it’s one of the many causes of heart attack/heart disease 🎉❤

[@andredaedone7732]

@@thehassanhashemi Stop believing what mainstream fools tell you. It isn't the LDL it's the VLDL along with garbage sugar intense diets. Stress from life and garbage food starts the damage....

[@polotsk]

Thank you! This is about me: very athletic and lean, high HDL, low Triglycerides AND high LDL. My primary care doctor wanted to put me on statins, I said NO. I read a number of studies that talk about it. This lecture is along the same lines but easier to understand and very complete.

[@hartpranatran]

I recently was told that I needed to go onto statins as my ldl is too high (4.4). He didn’t bother to asked me about my diet. I told him I don’t eat junk food, not fatty food, lots of vegetables and has maintained a very healthy diet within the last two years. And on top of that I exercise between 4-6 days a week and I have never felt better in my life. He simply told me that unfortunately it’s the gene? I am 47yr and compared to my friends i feel like I am in my thirties. He never bothered to explain to me that my triglycerides is low (1.0) and my HDL is high (1.2), which puts me in the “isolated LDL” category. Thank you Dr. David, otherwise I would have taken the statins.

[@robertpekin2995]

I have the same story, Dr never bothered to explain or ask about my diet just put me on Statins. I’m 61 and sure I need to get fitter but I’ve eaten a clean diet all of my life and feel great. Everything else is good except for LDl I havnt gone to the chemist to get my script

[@boboallin]

Sorry but 1.2 isn’t high hdl. It’s not super low but it isn’t great. Same with triglycerides 1 is fine but it’s nothing crazy. For comparison my hdl is 1.9 and triglycerides 0.5. I still am a bit iffy about my ldl though 4.9-6.8, higher when I’m training a lot weirdly

[@vivianrose6805]

I shall listen to this with interest when I get home from hospital. My husband and I worked hard at educating ourselves on this topic. For the last 2 and half years we have been committed to a carnivore diet and plenty of exercise. Before we began I had a CAC score of zero; this aged 69. I had always been a very fit, lean individual : my cholesterol levels went up; total cholesterol 18; triglyceride:hdl ratio excellent. I was pleased to be a LMHR. 10 days ago I had a heart attack: LAD. I was fortunate to get treatment. A stent was fitted but after the procedure I suffered a succession of seizures and was intubated for 3 days. I am still in hospital; I have pneumonia and several medications, whereas I had none before and could run up hills. For the present I am taking what is recommended and trying not to obsess about the way forward. However it it shocking and I feel that someone needs to examine my experience. The future isn't looking good for me especially as my BP is very high.

[@rhodon546]

My God, I hope you're doing better now!

[@LowCarbLowDrama]

I absolutely love how Dr. David Diamond, PhD, and Dr. Nadir Ali, a cardiologist, present CVD data. Every mainstream healthcare professional, particularly cardiologists, should receive a copy of or a link to their videos. These two and Dave Feldman are my go-to CVD information heroes.

[@toonybrain]

I wonder how many would be open to bucking groupthink? I just visited with a cardiologist who is “cookie cutter”: he gave me the LDL lecture I expected. Statins prescribed. I’m a fairly recent carnivore: I first learned about it in late February, Carnivore made perfect sense, and I was persuaded by the thousands of glowing testimonials accompanying YT videos. I can’t help but think Carnivore was a nudge by God to save my life; my test results could have been much worse if I were tested back in January before Carnivore (i.e., CaC). I’ve lost weight on Carnivore without trying, I will continue on Carnivore/Ketovore hoping to see improvement in my test scores like so many other Carnivores in the comments on various videos. I’ve always been an extremely active person, try to thrive drug free, and I felt healthy overall. My plaque was a stunning surprise (in the widow maker and one other artery😬). I’m thinking my artery damage may possibly be a side effect of Cisplatin cardiotoxicity (15 years ago), or my artery predisposition is genetic. IDK

[@Maintain_Decorum]

🙏👏🏻💝 I cannot express how much I appreciate the work of David Diamond.

[@JayJay-un3rp]

Has anyone noticed that they have been less sick since their LDL has been a lot higher ?? and obviously low triglycerides and higher HDL

[@finetrue]

Always have high fat diet and high LDL as LMHR. Went to a state park in South Korea for 2 weeks where there was almost nothing to eat but all kinds of mushrooms. Could not find any quality oil except for corn oil, which I did not take since they are basically poisons. I have never been sick for years, but this time, got a cold out of nowhere (not covid or virus, simply a cold). I think it is because of the weakened immune system due to the lack of healthy fat😅.

[@colinvankeith4814]

Yes

[@davidluke1747]

Yes

[@ssa8479]

@@finetrue yes. Also found and working with an endocrinologist to come off thyroid medication. All those wasted years of low fat, low salt, don’t eat eggs, minimize red meat, use margarine and not butter, followed the food pyramid.

[@font322]

What about Apoe4?

[@garyroach8624]

Thank you Dave Feldman and DR Diamond for a fascinating presentation.

[@Oscar_AH]

This talk comes to me in perfect timing. I just got my LDL test results as 560

[@BeefNEggs057]

Well done. Must be carnivore to be doing that well and I mean that. High LDL is great assuming your Triglycerides are low and your hdl is high. To be that high on LDL you have to be zero carb or very close to it. Don’t let your doctor discourage you. Keep up the good work and avoid those bungholes. They’ll just discourage you and ignore your amazing results and hyper focus on LDL. Cardiologists are the worst - avoid unless you need a CAC, but do not listen to their BS.

[@ssa8479]

You earned the bragging rights, friend. I'm 'only' at 446. Hope your HDL are high and triglycerides low.

[@crowley9312]

1 year carnivore, HDL:81 TRIG:70 LDL:337 TRIG-HDL RATIO: 0.86 I am wondering if lmhr and ldl levels increasing on low carb is more common than previously thought, as I see and hear so many reports of this. Perhaps it's just the natural healthy state.

[@ssa8479]

@@MichaelDirk I'm not sure you fully understood my comment. Oscar_AH reported an LDL of 560. He has 'bragging rights' as in higher reported on this thread. Not a cause for celebration, not necessarily a cause for worry if the triglycerides:HDL ratio is good. Clear enough now?

[@newyorkguy158]

@@Oscar_AH Very dangerous, because it raises ApoB lipoprotein particles which cause heart disease, as I explain in other comments. The longer it remains high, the greater the risk of heart disease and stroke. Don't let anyone here mislead you. Lot of ignorant people here.

[@garyjackson4054]

Some of this first rate lecture will require further study by many non medical professionals to fully understand the implications. Essential viewing for all primary care professionals. Thank you Dave and David, this is such valuable information.

[@Education-yk5ug]

I've watched quite a few videos on LDL, statins, CVD, metabolic disfunction, etc. They all were useful but as a regular person and not a medical professional, I still felt there were gaps and inconsistencies in what they all were saying, each in theor own way. This video brought it all home for me. Detailed enough but not overloaded with medical terminology and complex descriptions. Very concise. The most important conclusion which unfortunately I didn't hear in any other videos: - high LDL is not indicative of whether or not you are at risk - LDL has to be viewed in a context of other markers, at the least: Insulin, Triglycerides, HDL - using statins will help if those other markers are not good, but it will be practically useless if they show that you are in a good metabolic health - if your LDL is high and you have metabolic disfunction you have a choice of either taking statins with all side effects, or take a lifestyle approach. I'm just really disappointed that our main stream healthcare ignores all this and my doctor immediately sends statins prescription to my local pharmacy as soon as he sees an elevated LDL in my blood test.

[@CaroleMillington]

These videos are a really big help when I get my blood test cholesterol results back. My Triglyceride/HDL ratio of 1.14 is the best it's ever been on Carnivore but it's just so hard to not get concerned about the rest

[@charlesincharge3404]

"It's just so hard to not get concerned about the rest" because we've been repetitively fed a bunch of bs our entire lives. You're only human after all.

[@SiriusStarGazer]

@@charlesincharge3404 this is exactly what i am going through right now. The brainwashing is giving us the gitters. My trg/hdl ratio is 08 but my ldl is 183 from december when it was 132. All other markers improved. My trg was 119 , hdl 52 prior to low carb diet. Ironically, i went low carb to decrease ldl , and trgs.

[@atoms-to-atoms]

Dave this is the second video posted that I could not get enough of!..brilliant as a HMHR much appreciated.

[@plflaherty1]

This one is a gem! Thanks

[@larsnystrom6698]

This presentation by David Diamond has a few things more than the one I listened to years ago. Perfect for the medical profession, which obviously hasn't had anything like that in their education. For us others, we just have to remember that from the doctors usual lipid tests it's still just the triglycerides to HDL ratio (ideally below 1.7) we need to be concerned about, not the LDL-C. And to avoid metabolic disease and diabetes, of course!

[@marianormamojares8624]

I love Dr. David Diamond because he speaks very clear. I can easily follow him. Thank you doc. I'm a Filipina here in the Philippines. The doctor diagnosed me just recently with hypertension, high blood sugar and high cholesterol. He wanted that I should take Atorvastatin, Cloripedogrel, Lozartan and Amlodipine. I'm scared, so I didn't do it.

[@amyberger-ketowithoutthecrazy]

Absolutely effing STELLAR!! 💥💪 Will be contacting Dr. Diamond privately in the next day or two to discuss the influence of thyroid hormones - specifically T3 - on serum lipid levels. We are long overdue to have a nuanced discussion about this in the keto community. Looking forward to your conference next year, Dave. I didn't come to this first one, but I won't miss the second one, my friend.

[@aliazig]

What about T3? I just had some lab work done, my Cholesterol is sky high , my Trig are very low, HDL is high, T3 is a bit low. Is there a connection?

[@juiceboxboy8143]

Great presentation! The contrast between when statins are beneficial and when they are not was really helpful.

[@Kjuken69]

Mabye they can to a degree, but not for lowering colesterol, but maybe for inflamation.

[@aprilek6003]

Loved this talk - thanks for posting Dave

[@nafisaaptekar3601]

This is a priceless podcast thank you

[@barbarapecka4935]

Thank you thank you Thank you

[@oscarbubb5154]

wow what an eye opening lecture. thankyou doctor

[@scoobtoober2975]

Thanks for the studies and info. Very helpful. A few folks i'm around sometimes need a coax to do something, others need it to not worry so much.

[@datanation17]

I found this presentation reassuring that my change over to keto is a good choice.

[@charlesincharge3404]

Absolutely, and stick with it. My advice would be to avoid most everything packaged as "keto-friendly" in the supermarket, as well as making keto snacks for yourself. That's defeating the purpose...imo

[@barbarachen1428]

Fantastic lecture, thank you!

[@schaef1722]

I’m so thankful for this information, I have known this for a while, but I feel like now I’m armed better so I can’t let my cardiologist stop fear Mangling me. My ratio of tri/hdl is 1.1

[@Knowledge-b6o]

Amazing presentation!!!!!! ❤

[@lesworks]

I had no idea of LMHR as a dietitian/competitive runner who fit these parameters fully in my 50s and pushed back on my community that pushed statins hard. A decade+ later, newer fractionation tests separating peak LDL vs. sm particle LDL (mmols vs mg/dl) are making me nervous as my ApoB , Lp(a) and glycalation have shot up in 8 months. I drew blood a week after experiencing a tibial plateau fracture (reduction). And now 6 wks post surgery I've lost so much muscle mass (except forearm/delts=crutches) my leg looks famin-like while the other is Roman-greco. The other thing noted as I started wearing a cgm a week before the accident (curious mind)I'm becoming insulin resistant. My Lepin is "2" so literally, very little body fat (BMI 24-25) and a zero CAC score. I'm 64 female on no meds, Hx HIIT, intermit fast and lots of energy. Is there anybody else who's experienced similar.

[@thehassanhashemi]

Great service to society

[@anthonylawrence5842]

I'm a typical LMHR case. LDL 200 HDL 90 TG 30 - Keto diet 10 years age 73 never been fitter in my life.

[@jy4893]

Excellent!! Life saving information!…The The information is EXCEPTIONALLY well communicated. Thank you and God Bless 🙏

[@midasracer]

Great story. Just had my blood test sine I became 60. I follow a healthy diet and do a lot of work outs. My LDL and HDL was skyhigh, 50% over the limit. My doctor wanted to medicate me. No I said look at my triglycerides and glucose level. Very low. Unbelievable that doctors still don't have this info. Luckily I have done a lot of research and don't take any medicin.

[@mowthpeece1]

This was pure genius. I have longevity genes. So of course I'm a LMHR. LDL is protective. Carnivore has thrown my LDL, which was always pretty high, into the relative clouds. I have a theory for WHY LDL goes up when eating high amounts of meat. I haven't seen that explanation yet. I'm going to keep looking before putting it out there. Thank you for a great video!

[@laurastabell2489]

PFAS is inhibiting PPAR enzymes causing dislipidemias and metabolic syndrome. Thats whats causing the health issues. Fatty liver is 30% of the population. Obesity is predicted to be 30%. Older people didnt get exposed until they were older. Its children developing with PFAS exposure in utero that are not living as long as their parents do. Children are prematurely aged with adult onset diabetes and obesity in epidemic levels. Fats you eat cant be burned in mitochondria or broken down for uses like fat based enzymes, vitamins or hormones. Instead fats build up everywhere. Meanwhile the high energy areas of the body are going haywire for fats and energy. The brain sends out a message for more food! People are fat but starving for fats. Mitochondria cant process efficently without fats. We feel so bad without realizing it that keto diets- that are really inefficient make people feel better. Less brain fog. You cant burn sugars well without fats! Forever fats also are moved into cells mistaken for normal long carbon chain fats. Those forever fats cant be broken down so just sit in cells.

[@leighnapier4505]

Thank you so much for this vindicating video !!

[@tereseawalker4516]

very good lecture!

[@ceegeevibes1335]

finally i see the connection. this is a very illuminating talk. !

[@SharonH65]

My LDL in 2017 was 99 I had calcium in arteries a stent was put in 2018 my LDL was 148 and today 8/2024 my LDL is 130 I have not any issues. I have been on carnivore for about a month. I was on statins created muscle pain, she took me off one and ordered another this year, I have not taken them. I am just trying to learn more about this cholesterol,LDL situation.lol thank you so much for this information🥰🥰🥰

[@aaarrgg50]

Sharon.. may I ask your age.. I’m 62 and was wondering when I should start to see a cardiologist.. thx ☺️

[@dwp2659]

great info - well done!

[@dougperrett332]

Nicely constructed and presented. I grabbed some of these studies from another of Dr. Diamond's presentations then gave them to my primary care provider.

[@sasharamirez2335]

I watched this while consuming a 2 inch thick ribeye. LDL 210, HDL 85, TRIGS 58

[@gingebrien2408]

My one last statement. Lean mass hyper-responders ( LMHR) is a bogus group assignment by those who are fixated on the cholesterol heart hypothesis. A strict Carnivore will have a high total cholesterol, high LDL-C, tryglycerides less than 100, and HDL 50 or greater putting one’s tryglycerides/HDL ratio less than 2. This equates to no Insulin resistance and a type A pattern LDL. The value that closest relates to CAD is a tryglycerides/ HDL ratio not LDL. No Association with CAD. To quote Cardiologist Nadir Ali, cholesterol is not the arson burning down your house, he is the fireman come to extinguish the inflammation. Those who see LMHR as an entity need to stop believing in a theory but follow the actual science. Use your critical thinking. Last but not least is Lpa really a risk factor? Or is it associated with CAD? Is it really a genetic mutation or a down stream effect of a toxic metabolism? Start reading the fine points of the research and stop accepting someone’s theories as fact. Stop being protocol pushers and start healing your patient through a proper human diet. Great presentation. Dr. Ginge

[@leighnapier4505]

325 TC , TRIG 145, HDL 55 , A1C 5.6. 63F on HRT, BP 100/60 Weight 110, Active, and on zero chronic disease meds . My Ca+ Score is zero. No statins for me ! My parents were put on statins , became instant T2Ds and both died w Alzheimer’s. “Never a statin” is my mantra ! Doctors need to catch up on science.

[@ParallaxView111]

My husbands family is being killed off with type 2 diabetes and Alzheimers. They would probably be living very long lives without doctors.

[@Arugula100]

Wish you would define and clarfy what FH is? Whst it stands for?

[@LorileeWI]

Thank you Doctor, again. I've been following your lectures since you exposed the statin myth. Shared those videos withany friends . God bless you!

[@orchidmuse]

Great thanks for all of you, researchers and docs for finally giving answers for those with FH and genetic dysfunctions. You have not yet mentioned people who are hyper absorbers of cholesterol. Hope there will be a study on this issue too - concerning saturated fat. ❤🎉

[@sdjdad9]

Check Dr Paul Mason. His KZbin channel has information re Saturated Fat.

[@EatBeefBeHealthy]

I learned a lot. Thank-you!

[@johnsonpaul1914]

In other words eat low carb to get the trigs close to the HDL number and forget about LDL

[@BeefNEggs057]

Yes good. Carnivore is the only way to do that for me.

[@ucchi9829]

@@johnsonpaul1914 Dave Feldman would disagree

[@Malcolm-Achtman]

@@ucchi9829 Please elaborate.

[@johnsonpaul1914]

@@ucchi9829Diamond just said essentially the same thing I did, Listen to the video.

[@ucchi9829]

@Malcolm-Achtman Feldman does not agree with the idea of ignoring LDL-C. Look up his talk with Dr Avi.

[@charlesgriffin3262]

Thank YOU !

[@luckyhanger1326]

Awesome that you tell people what they wanna hear,. What can go wrong?

[@brucemckay6615]

A great talk… completely evicerates the trope that LDL is the enemy and that taking statins is necessary….

[@dan11D179]

Diamond has no idea what he's talking about, he's not qualified to speak on this subject. Low carb dieters experience 2.2x more heart attacks than standard american diet, with LMHR having the most.

[@saintwithatie]

@@dan11D179 Can you share your sources for these claims?

[@brucemckay6615]

@@dan11D179 prove it… where is your evidence…

[@AI-vs7sm]

Oh, ok, Dan, who are you to speak on whether Diamond is qualified Lets see your credentials! Maybe you got your sheepskin in the bottom of a box of Captain Crunch? Anyway, he is qualified enough to read the papers and expound on the graphs, anyone can show us the study and highlight the statistics on the screen! You know ,like Neal Barnard and Mikey Gregory do. Are you saying the studies are not correct?

[@ucchi9829]

Nope

[@Dermsurg1]

Dave: when will you release the results from the LMHR study??? Many of us are living with keto-induced elevated LDL and we need to know about CVD progression in those with some underlying disease (like myself). PUBLISH ALREADY!!!!!

[@elenabidochka8665]

I have very high LDL and my Apo lipoprotein B is 2.69G/L. I have no inflammation, low triglycerides and my recent carotid artery scan shows no calcification. Although I have never been diagnosed with FH and have no other symptoms other than the high cholesterol, my father had high cholesterol as well. I am a 62 year old female, and I consider myself extremely healthy and practice a lower carbohydrate, diet, combined with weight training and bicycling. I was hoping you could comment or if you have another video you recommend that I could watch.

[@bluesgene3010]

The issue that isn't addressed that I'm dying (no pun intended) to know is: what about those folks who already have plaque and a high, or moderate, CAC score but have been following the low carb guidelines for a number of years, resulting in low trig's., high HDL & LDL as well as large LDL particle size? Should THEY be concerned? Or might statins be a consideration for THEM?

[@perrysebastian6928]

Whooohooo! part of the immune system! Good to hear this discussed.

[@cynthiahowden4165]

Awesome learned so much

[@sdjohnston67]

Excellent!

[@morayjames92]

is treating familiar cholesteremia with a pcsk9 inhibitor a wise thing to do or is a low carb high fat diet a better option? thanks. any links to learn about this would be welcome.

[@docgl8301]

Excellent information. Who is considered an "elderly person". Also, my understanding is the post menopausal women naturally produce high LDL-C levels because of estrogen hormone reduction. Is this rise in LDL to thwart disease and should it be treated with statin drugs? Also, can the endothethial glycocalyx be repaired?

[@matts2758]

Dave did you have any luck with getting David to meet with established experts in the field like you did with William Cromwell? Would be nice to see David have his evidence challenged by someone who might be able to explain the findings in the wider context of the literature such as all the evidence provided by the EAS to the contrary.

[@hannibruhngrann9211]

Some people have trouble remembering which one is the good one H(hurra) DL I'm Danish, and the other one, my called L(lorte = crappy)DL. But one, actually, just needs to remember the good one

[@schaef1722]

My ldl on last lipid test was 340 I’ve been low carb for at least two years now. I followed it up with a NMR showing very high large particles and very low small vldl particles. But my cardiologist only says it’s way to high I need statin therapy now! 😢

[@SamShank175]

So, what if you have LMHR numbers and high LP(a)? My numbers are good for every way you can measure insulin sensitivity and I had a zero CAC in 2022 at age 47.

[@amy11228]

I'm female, age 44, LMHR and high LP(a). I also have low insulin and glucose. No CAC score yet, but I am encouraged to read your experience! The LP(a) freaked me out.

[@kaweka260]

Started Carnivore 2 months ago and Tryglicerides/HDL are 130/85 with a ratio of 1.5. I was expecting my Tryglicerides to come down lower from 167 but my HDL went up from 71 to 85. Maybe because I did not drink as much water between 6 pm and before my blood test which was at 9 am during my fast or should I have fasted longer than 14 hrs. Is that still an ok number for my Tryglicerides though my ratio is optimal? Thoughts please.

[@lindabirmingham603]

Give your body a few more months to heal and retest. You're going in the right direction. I read somewhere that a 16 or 18 hour fast may be better for some Carnivores.

[@directajith]

So you had a tg of 771. ( It looks like 77.1 from the chart) . But you didnt tell how you reduced your tg ?

[@krakoosh1]

Were you saying there is a connection between an excessive number of small dense is a cause of higher coagulopathy?

[@deltanine2468]

No mention of being lead singer for Van Halen??

[@diablominero]

If you have untreated FH and make it to 70, you're definitely not sensitive to LDL-caused heart disease, so you have fewer heart disease risk factors than the general population. Similarly, if people commonly died of bee allergies, beekeepers would be healthier after age 70 because only non-allergic ones would make it that far, but that wouldn't make beekeeping protective.

[@wocket42]

There is no LDL-caused HD, though.

[@diablominero]

@@wocket42 obviously there is, because some people with FH get heart disease as young children (well before anyone else does), and people with PCSK9 loss of function mutations have dramatically lower rates of heart disease than everyone else.

[@Paul-dorsetuk]

Brilliant.

[@laurastabell2489]

Clotting is also influenced by protease inhibitors especially Serpines. Serpinopathies are diseases caused by lack of Serpines. Thrombosis, cirrhosis and emphysema are three of many serpinopathies . Most are clotting disorders. Protease inhibitors are small proteins that are one use spring loaded pac men molecules that snap down and eliminate protease. Protease is like a docking port that creates a way into cells. It softens cell walls. Serine is serpines nemisis. Diseases like Covid use proteases to get into cells. High inhibitors protect cells. They also work to keep cells living longer. Lab grown cell lines are protease inhibitor treated. Seeds are foods high in protease inhibitors. The more inhibitor in a seed, the longer its viability or life. Heat damages these delicate molecules. We were descended from a smsll squirrel like animal that may have lived on nuts and seeds. Fire cooking is only a few hundred thousand years old. Before fire and modern projectile weapons, we probably ate more raw seeds. Now we dont. Even watermelon has no seeds. Cucumber squash family fruits have high protease inhibitor levels if eaten raw. Haggis is another source of protease inhibitors. Think of the extreme damp windy cold climate in Scotland. You need super foods to survive. Beef stomach is actually illegal in America! Theres more money to be made in illness. No doctor tells you to eat raw seeds. Many nuts and seeds are heated or irradiated damaging the protease inhibitors.

[@OmangOming-tc6ep]

My LDL is 224 , HDL 50 , TG 39 . I am not considered a LMHR as my HDL is below 80. I am on a low carb diet for many years. Wondering why my LDL is high.

[@mowthpeece1]

You're Lean Mass Hyperresponder-Like. He mentions those, which includes me, too. All my numbers are perfect except for LDL at 193.

[@mdV-7-1]

What's FH and LMHR?

[@robinbeers6689]

Familial Hypercholesterolemia and Lean Mass Hyper-Responder.

[@jupiterthesun3217]

Totally makes sense, it’s a matter of taking into account do many variables and as a Person who’s metabolically damaged ! I can now see the benefits of taking statin Although I’m not looking forward to the side effects because I’m already challenged in those areas .

[@mrkevans13]

When he says LdL does it matter if it’s ldl small that is high?

[@mowthpeece1]

Yyeeeeeeeesss! Those are the dangerous ones. You're eating too much sugar and processed carbs.

[@PursuitAthleticTV]

Great summary as always Dr. Diamond, thank you. It should be noted...at least IMHO, that the damage done by statins far outweighs any potential benefit for lowering risk of heart disease, for ANY population. To think of it another way...if you're metabolically unhealthy (you're not likely reading this anyway, but...) and can lower your risk for heart disease slightly with a statin, are you willing to accept dementia and/or cancer as the tradeoff, with the possibility of earlier death? Food for thought.

[@glenntimberlake2413]

Exactly. Why not feed the brain with 2 grams of high quality fish oil and consumption of fatty fish. The DHA is necessary for the brain. The EPA is necessary for the cardiovascular system and heart. Dr. Stern Ekberg has a good podcast entitled : “What happens when you take fish oil everyday for 30 days?” A lot of excellent points in understandable language while touching all the key facts. A clear science based understanding. Clears up and corrects a lot of misunderstandings that are stated every day.

[@Arugula100]

What is MHLR?

[@espinosalexis]

All these is making Peter Attia and Simon Hill (and their supporting guests) look dumb. I hope they have the courage to invite you to their shows and talk about this!

[@lindasophiasworth]

What group sponsored this conference ?

[@SallySamsara]

LDL does not equal LDL-P. Any studies looking at LDL-P vs LDL-C?

[@rrrlasse2]

Those with FM, do they have (roughly) equal mortality because their cholesterol is lowered with medication? I.e. the statistics you show, are they for treated or non-treated FM people?

[@dalialovesdoggies4361]

😢 6:21 😢😢😢WHAT IS FH PLEASE

[@billcrowell5096]

Would you please link the papers cited by Diamond into the show notes?

[@firelight-vitality]

I often wonder why people don't take the extra step to include links to studies in their descriptions. It would make it so much easier to verify and understand the information being shared.

[@jeremynass2040]

Yeah, it's unfortunate they were not posted, but, the titles are clear in the presentation so you can just copy down the titles and search. The papers will come up.

[@CvoreAthlete]

So 14 months carnivore, HDL 98, LDL 105, TG 50. I must be a lean mass HYPOresponder?

[@Shakerhood69]

LMHR is LDL 200+, HDL 80+, and very low Triglycerides

[@MJ-hl1kk]

FINALLY, got the c!arity I needed - after TWO years of research! If I had had this knowledge a decade ago, my brother and parents would probably still be alive. HUGE regret. The statins and certainly, the lack of knowledge about diet and lifestyle did them in.

[@Arpatube]

Something interesting: I think I am the opposite of LMHR: Just got my blood work, 37mg/dl HDL, 98LDL, 146 trigliserides. And the kicker is I am low carb, my daily average for macros for the last two weeks are 95g fat, 50g carbs, 105 protein. I tried carnivore before that and introduced some veggies and a lot of eggs lately. I have no energy I think things are looking bad... I dunno what's happening.

[@mowthpeece1]

You're not designed for low carb. You need glucose. You're probably from an early agrarian people. Well aclimatated to complex carbs. But you need to research before you get worse! Good luck! ❤

[@CvoreAthlete]

Carnivore HDL 105 LDL 100. TG 50.

[@firelight-vitality]

LDL 100? That can't be right!

[@CvoreAthlete]

@@firelight-vitality haha don't know why you say that but it is right

[@mirandathorpe4117]

HDL 100 LDL 137 TG 89

[@finetrue]

It is funny to see how people attacking this talk without showing any evidence claim they are more qualified to speak their views, definitely not as “scientists” that they look down on, but maybe as a “doctor” that they refuse to prove 😂

[@ucchi9829]

@@finetrue Diamond is not a domain expert here.

[@Tee667]

Ya know I’ve come to see comments such as these as BOts. They make no sense other than to cause a reaction and an illogical one at that

[@ucchi9829]

@Tee667 I'm not a bot. Diamond literally told us what his domain is and it isn't Lipidology. He's just some armchair scientist that happens to align with Dave Feldman. Sort of.

[@Tee667]

@@ucchi9829 I wasn’t referring to you. I was referring to the comments that you mentioned

[@ucchi9829]

@@Tee667 oh.

[@stephen562]

What is the difference of someone who has FH and someone with high LDL?

[@Shakerhood69]

FH is a genetic issue if my understanding is correct

[@TheKlh54]

What is FH? LMHR?

[@reynolds753]

Does a low-carb diet improve ApoB ?

[@newyorkguy158]

Only if it is low in saturated fat. Diets high in saturated fat lead to LDL cholesterol synthesis, which requires more ApoB particles to transport it in the blood.

[@albi7]

Unfortunately Professor, like many other researchers, misinterprets statistics. Let us look at the chart at 11:11. He says that the difference between the baseline and people with FH with low insulin is insignifiant. But that does not mean it is not there. We can clearly see that people with FH hat 50% higher risk of devloping CAD. The fact that it is not STATISTICALY insignificant, does not mean it is not there. The study was probably underpowered. I woud guess that if there were confidence intervals included it would probably be borderline significant.

[@user-xr9db2zw7y]

What are LMHR and FH?

[@acke26]

LMHR (Lean Mass Hyper Responder) These lean people's LDL increases massively on a low carb diet. Their Triglycerides are low and their HDL high. FH (Familiar Hyperlipidemia) Genetic abnormality when it comes to their lipids.

[@user-xr9db2zw7y]

@@acke26 thanks

[@Aurora-zy6lq]

@@acke26 Thank you

[@ElaineChong-ev5zu]

​@@user-xr9db2zw7y Familial hypercholesterolemia....

[@mr8966]

Isn’t a small dense LDL a HDL??

[@mowthpeece1]

No. It's a glycated LDL. Sugar attached to it and changed it's shape. It no longer fits in the LDL receptor and is seen as an invader and is attacked by microphages. This creates foam cells which reek havoc on your arteries.

[@mowthpeece1]

Oh, and it got small because the triglyceride was released from it first. LDL is the bus that takes triglycerides to your cells, HDL picks them up and takes them to your liver.

[@dorianmichelarmenterossanc668]

What is FH?

[@stephenthompson4952]

Forget about cholesterol .PERIOD!

[@mowthpeece1]

That's not what he said. You need to measure it to find those with metabolic disorders. Imagine never looking and having someone with all the wrong numbers. They just need to learn to read numbers right, and choose the correct tests. But that's what science is. Learning.