B cell Activation and Differentiation (PART 1): T Independent Activation (FL-Immuno/48)

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Пікірлер: 48

@taiso.6227 9 ай бұрын

These immunology classes from this channel have been enlightening for me! I searched a lot here on KZbin, for sure, but these were the most didactic ones possible. Thank you very much.❤

@leob9534 Жыл бұрын

Excellent thank you so much !! A little precision, from single cell RNAseq data, I can tell that unswitched memory B cells are produced in large amount and can be found in the blood (around 20% of all memory B cells are IgM )

@mangocookie601 3 жыл бұрын

Whoa, I always imagined Plasma Cells as Super Saiya-jin versions of B Cells Great Video! 🙂👍

@CTCDburp Жыл бұрын

What does that mean?

@priyamanoj3896 4 жыл бұрын

Thanks a lot for making the concept very short and clear 🤗🤗

@ruqayahakhtar4413 3 жыл бұрын

Frank lectures 😚❣make me frank in zoology💞💖👌👍👍👍

@Micro-life 7 жыл бұрын

Great👏👏👏 ....frank lecturers hlp me a lot...bunch of thanks.... Sir waiting fo Part ll 😇😇😇

@FrankLectures 7 жыл бұрын

+Bratati Paul thank you for your feedback

@pranav6143 2 жыл бұрын

@@FrankLectures Is the clustering of antigen equal to PAMP,if not then how,tlr bonds the cluster of antigen?

@adammajaliwa3125 2 жыл бұрын

U made it madam🙌.nice,short and Very educative i lovd it❤️

@eyal9654 6 жыл бұрын

The Best! Much thanks to you ma'am

@FrankLectures 5 жыл бұрын

Thanks

@Mouni-j92 2 жыл бұрын

You are amazing thank you ❤️❤️

@malikdesilva6574 Жыл бұрын

great effort.thank you!

@reshmisebastian5649 3 жыл бұрын

Thnku for make it easier.

@ramchandrasuthar2848 6 жыл бұрын

Great analysis God bless you

@FrankLectures 6 жыл бұрын

Thank you for your feedback.

@shilpigiri25 3 жыл бұрын

Very easy to understand..... thank you

@ramchandrasuthar2848 6 жыл бұрын

Very nice explanation

@miqdadulHasan 7 ай бұрын

Just wow!!

@Param_Sir 6 жыл бұрын

Mast he boss. Nice

@FrankLectures 6 жыл бұрын

Thanks

@noraahmed6135 5 жыл бұрын

Thank you very much.. Please I need a lecture about adhesion molecules

@ahmedelsakka9548 4 жыл бұрын

in absence of T-helper cells as in Digeorge syndrome or HIV , how does B-cell react to antigen peptides ?? does it get activated and produce IgM or not ?

@wafaqa4236 6 жыл бұрын

Thanks alot

@pranav6143 2 жыл бұрын

Is the clustering of antigen equal to PAMP,if not then tlr bonds the cluster of antigen?

@yokogarner4922 5 ай бұрын

An antigen with multiple/repetitive/ identical epitopes has PAMP( pathogen associated molecular pattern). Many BCRs attracted to a single antigen with muliple/repetitive/ identical epitopes, creating clustering of BCRs. BCRs are being bound by a single antigen ( cross linking to activate B cell) The author said that is Signal 1. And in addition to Signal 1, B cell express TLRs that bond to other molecules on antigen, that is Signal 2. So, I think your confusion comes from clustering of antigen. It is clustering of BCRs to a single antigen, not cluster of antigen. A single antigen has many different epitopes. TLRs bond to other epitopes.

@sabux4420 Жыл бұрын

i dont understand how having multiple repeating epitope can trigger clustering of the BCR. please explain

@yokogarner4922 5 ай бұрын

BCRs are atracted to a single antigen with multiple/repetitive/identical epitopes, and that creating clustering of BCRs which brings increased accessory proteins production to initiate signaling process without T cell help.