Bartter syndrome - Dr Bhatia

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- / drgbhanuprakash
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- linktr.ee/DrGBhanuprakash
Bartter syndrome (BS) is a hereditary condition transmitted as an autosomal recessive (Bartter type 1 to 4) or
dominant trait (Bartter type 5). The disease associates hypokalemic alkalosis with varying degrees of
hypercalciuria. It is a consequence of abnormal function of the kidneys, which become unable to properly
regulate the volume and composition of body fluids due to defective reabsorption of NaCl in a specific structure
of the kidney called the " loop of Henle ". A first consequence of the tubular defect in BS is polyuria. Indeed,
high urine volume is already present during fetal life, and is responsible for particular complications of
pregnancy, i.e. polyhydramnios and premature delivery. Low potassium levels in the blood may result from
overactivity of the renin-angiotensin II-aldosterone hormone system that is essential in controlling blood
pressure. To date, at least five genes have been linked to BS, and characterize five types of BS. BS type 1 is
linked to mutations of the gene SLC12A1 (Solute carrier family 12 sodium/potassium/chloride transporters,
member 1) on chromosome 15 (15q15-q21.1). BS type 2 is linked to a gene called KCNJ1 (mapped to
chromosome 11q21-25), BS type 3 is linked to the gene ClCNKb (mapped to chromosome 1p36) while BS type
4 is linked to gene BSND (mapped to chromosome 1p31). BS type 5 is associated with activating mutations of
the CASR gene (mapped to chromosome 3q13.3-q21). Patients with BS are usually symptomatic early in life
(occasional patients with BS type 3 or type 4 may even reach adulthood with few if any manifestations), growth
is usually below the age standards and final height may also be compromised. At present, BS cannot currently
be cured, and treatment is mainly directed at correcting electrolyte disturbances, i.e. hypokalemia and possibly
hypomagnesemia.

[@DrRahulsharma-ll3pr]

Appreciating 👌

[@srinivasaraosirasapalli5104]

thank you sir for a nice lecture

[@DIPn2G]

My daughter was diagnosed with classic Bartter syndrome recently and this has dramatically changed our lives. I wish there was a cure for this horrendous syndrome because I don't like seeing her suffer this much. 😢

[@davidvines6048]

I have Bartter Syndrome. I don't have a ton of knowledge on this disease because my mom typically handles my medical needs, but you should look into something called "crispr" for your daughter. To my knowledge, Bartter Syndrome is caused by either mutated of deleted genes and "crispr" is a new medical procedure to edit your genes, thus (in theory) curing the disease. I hope this helps. God bless you and your daughter.

[@subhamsikdar1715]

Awesome....

[@srinivasaraosirasapalli5104]

great concept from genius

[@mariellebernard569]

thank you so much!!!!!

[@danielthorne1785]

I just learned more about myself -daughter

[@aysiathorne6656]

Awwww dad 🥰

[@aysiathorne7644]

I love you dad 💖

[@sntr5338]

thx professor

[@Xyz-sp6qt]

Great lecture

[@doctorbhanuprakash]

Glad it was helpful!

[@alzaimalhilaly]

Hello Dr. My daughter suffers from Parter syndrome and weighs 5.900 at the age of the year. Is this normal in her condition?

[@shahidahmad2578]

Mera betha b bartter syndrom hy .is k liye behtr elaj kya hy .

[@shahidahmad2578]

Plz anyone to help me to witch doctr i contect

[@bangalorecatering5147]

Hello my children are having barter syndrome past 15 yrs for my son he is into supplementary with potkolor potassium chloride syrup free & endomatcin capsules treatment from manipal hospital to st John hospital

[@bangalorecatering5147]

Please tell me treatment for my son is having allergy problem & weakness

[@uniquecooksfood8012]

How do you control the the posstasium levels because it goes really low

[@berlosconis]

It depends. I assume calcium gluconate, insulin, d50, bicarbonate or even albuterol

[@mehwishsajjad5455]

sir recently I deliver my daughter ...in whole pregrancy I had the patient of severe polyhydromnios ...my daughter has a bartter's syndrome...is this treat able?

[@jiyamakhija2891]

Same problem

[@Neerajtamboli09]

My son have also same problem What I do

[@mariasolo9209]

Watch this to learn more about my disease

[@diwakarkoirala4879]

why is there excessive secretion of prostaglandins in bartter syndrome??

[@wanderer3561]

It's the other way round. Neonatal Bartter syndrome occurs due to excessive PG

[@diwakarkoirala4879]

@@wanderer3561 okay thank you very much. Sir can you elaborate?

[@growwithpgh1942]

Hello my son is 5 years old and was diagnosed with antenatal bartter syndrome.. Just very recently i have created a youtube channel hoping to create mire awareness of this illness.

[@Neerajtamboli09]

Pls send me channel link