Structure of a Spliceosome: Molecular Framework for Understanding Pre-mRNA Splicing

[@saturnorbit6810]

It was a beautiful video and has much better rendering of detail than most educational videos. I highly promote this sort of advancement as this is what will ultimately engage the public on the sciences. This is coming from a grad student in molecular biology in California and I'm sure other students and undergraduates would agree.

[@invin7215]

The complexity and beauty of nature is staggering. What a time to be alive that we're starting to see things at such an incredible level of detail.

[@陳文毅-o3b]

just let your know how good you are to make this concept visualized. I do really appreciate what you have done to make me understand this subject better.

[@baraskparas9559]

Magnificent presentation. Thank you. Both spliceosome and ribosome assemble on Myrna, both have RNA core ribozymes and both assemble from 5 major units but the spliceosome has evolved down a path of flexibility ~300 alternative proteins in humans wheras the ribosome is much more conserved within each of 3 domains of life.

[@eugenlazaj2147]

The illustrations are beautiful.

[@mariannaweener]

Great descriptive and clear animation. Thank you so much for creating and sharing! 👍

[@Arendt-Foucault]

And they recently resolved the structure of human spliceosome (catalytic step I) , Bravo!!!!

[@Ash-zb7bu]

the graphics and animation are amazing! kudos to your team :)

[@jikarumiromoto5911]

Beautiful rendering. Thanks for sharing Beauty of Science.

[@kelvin2736]

Thank you. Salute to the beauty of science!

[@lucaspedrajas5622]

how do we know its shape? it isn't possible to see under microscope , isn't it?

[@gvg9586]

thank you

[@DavidHaselbach]

Great work, which software did you use to animate?

[@beautyofscience2016]

You are welcome to ask the company making this animation: nmolecularsystems.com/

[@jessiemnglsuzuki3458]

Lovely, thank you!

[@manuelargos]

Magnífico!

[@shakedlw3394]

Well done!

[@DepletedUrbranium]

evolution tacked on where it always is... at the end.

[@Adelta21COD]

nice and interesting video, but I wonder if this content is really in relation with the channel. I mean this is advanced scientific analysis and explanation but there is nothing really beautiful.

[@beautyofscience2016]

Thanks for the comment. Just as physicists think equations are beautiful, in this case, the beauty is in the wonder of the life, thinking about a molecular machine can be this complicated and capable.

[@Adelta21COD]

Beauty of Science I understand your point. As an artist in search of inspiration, I love the beauty of nature in its shapes, colors and behaviors. Even tough I love science too, this video was a bit too complex for me to see the beauty behind those molecules.

[@niamcd6604]

Beautiful images, weird and slow commentary though.