Best Peptides for Well-Aging Skin!

Understanding Peptides and what they do. Recent peptide technology in skincare fascinates me. They're effective and have a wide range of benefits for the skin, addressing wrinkles, hyperpigmentation, texture etc. To keep it simple, I'm going through the different classifications of peptides, what they do and my favourite formulas.
Many of you ask me about EGF which is similar. Will talk about this separately!
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• Formulas Mentioned •
Signal Peptides :
The Ordinary Multi-Peptide + Copper Peptides 1% Serum
go.shopmy.us/p-1933088
Carrier Peptides :
NIOD Copper Amino Isolate Serum 3 1:1
go.shopmy.us/p-1933257
NIOD Copper Amino Isolate Lipid 1%
go.shopmy.us/p-1933255
Neuropeptides :
PCA Skin ExLinea Pro Peptide Serum
howl.me/ckO5X6FWxpe
Dr. Ci:Labo Aqua Collagen Gel Enrich Lift Ex
howl.me/ckPzAaa94uV - 50g
howl.me/ckPzE44zEsp - 120g (what I have)
Enzyme Inhibitor Peptides :
NIOD Re:Pigment
go.shopmy.us/p-1933308
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My skin type : Dehydrated, sensitive. You may have a very different experience with the products I review if you have a different skin type or preference.
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This video is not sponsored. All my reviews and opinions are based on my own experience with the products which may not be the same for everyone. This contains affiliate links which will help support this channel! If you choose to use them, thank you for your support!
00:00 Introduction
00:35 Signal Peptides - Matrixyl
02:19 Carrier Peptides - Copper Peptides
03:13 Neuropeptides - Argireline
06:39 Enzyme Inhibitor Peptides - Tetrapeptide 30

[@axreason]

you truly are one of the best educators on this platform, Renée. i've been consuming so much skincare content on youtube and instagram lately, and this video just reminded me of how great your content truly is. sure, there are scientists, chemists and dermatologists on social media with a lot of knowledge in their fields, but i think you have a knack for explaining things in a very efficient and entertaining manner. probably the creator i've learned most from over all these years.

[@ifeolunu]

I really was just thinking this as well. She breaks down this topic so well!!!

[@gothamista]

Means EVERYTHING to me coming from you, who has been watching and engaging with me since the beginning of this journey! Thank you so much 🙏 Big hugs!

[@VsLeo1]

So true.

[@ginafriend1690]

I've said it before and I'll say it again, you walking talking encyclopedia you! The ability to absorb all that information, is astounding! You're even cute when you make faces! Got to hand it to you. Thank you, Renee! 🌹❤

[@CynthiaPful]

Love your in-depth look at facial products. You are wonderful.

[@mado.madeleine]

Yay! New Renée video 💃🏽 Thank you so much! This is super informative and helpful as always 🙏🏽 love peptides, they just feel so nourishing on the skin.

[@DrCarlaSeleme]

Tyvm for this insightful and well delivered video. I know what my holiday gifts are now. Best wishes to you.

[@tram7]

What an amazing video! Thanks for all the work you put into these super concise and informative videos!!

[@maureengreen617]

Wow, this is the best explanation of the various types of peptides I've seen. And I've seen a lot! I'm saving this video for future reference. Thank you!

[@1509rachy]

Thanks for the brilliant overview.. 🙏🏻

[@melbygrace]

Helpful and educational! I have my birthday wishlist now!

[@cecilieharris]

Thank you for breaking this down in such an easy way, peptides have always confused me, so this was super helpful. Also, lol at the added expressions around 4:30, this brought just the Friday evening laugh I needed :)

[@ST-fd6bi]

Great video, please do more of these🎉

[@twerk5954]

Would love the see an updated exfoliates vid from you!!! There are so many new products since your older video on it

[@Mnguyen92]

This

[@halfamo2422]

Brilliant and so useful, thanks! I do wish you'd talked about peptides and hair too ( a new video?). It seems a growing area of research

[@jackiee21]

I’ve been a subscriber for 5 yrs now, and everytime i need something for my skin i always check your vlogs and buy the products you mentioned. What i love about you is that you educate us well and you made sure you tried all the products you share with us. So you are my reference before i buy skin care, and it always works for me. Thank you. PS: when is the best time to use peptides? Morning or night?

[@gothamista]

Thank you, SO much for your lovely words and for watching me all these years! Copper peptides I use at night but any other peptide I would use day and night!

[@Likush100]

Thank you for such an informative video!

[@ammydinpuii7994]

What an informative video! Well explained with products. First time watching your video and I subscibe straight away!!! Thank you for the video

[@001pablotorres]

Thank you for the information!!

[@MyCrownstar]

Will you be doing box of skincare wishes this year!

[@kennethAmos8929]

I well love for you to make a video on the best K-Beauty peptides 😃❤️

[@manhac7541]

Please do a am and pm routine using your product’s recommendation please love from uk

[@tram7]

Would you consider doing a video on ceramides too?

[@wesoley93]

Surprised to not see the Allies of Skin Multi Peptides & GF Lifting Serum in the video

[@alineonbeauty6294]

Awesome video as always! That dr Ci Labo moisturiser looks amazing, look at that jiggle😂

[@almatoledo1608]

Renée, good evening. I tried Ci Labo the delicious gel like cream you reviewed in this video just now: 200% thrilled! I have well-aging, dry, and dehydrated skin 95% of the year (except when I travel to the tropics). Thank you very much! Just superb! I also have your essence to try soon.

[@ninanina4799]

Hi, I also have very dry and dehydrated skin. I would like to try this Ci Labo cream/gel but it concerns me it wouldn’t be moisturising enough. What are your thoughts on that ? It would be very appreciated. Thank you x

[@deborah972]

Hi loving your videos skincare 😊 xx

[@jowiens32]

I would be so grateful if you would review the brand Herbal Face Food! It’s has big claims. I used one bottle on a spot in my hair and it did go away. It’s expensive so I’d love a review from someone I trust.

[@wunna8657]

Thanks for sharing ! Love your lipstick what colour is it ?

[@kelleyg5184]

When incorporating any one of these serums into an AM and PM routine how would you layer? I use prescription retin-a.

[@PinCushionQueen]

Hey Renee! I’ve been meaning to ask you for ages, if you’ve compared Dr. Pickart’s (the OG ) of copper peptides to Niods copper range? I’d really like to hear your thoughts. I’m a long time user of Niod, most of my fave products are from their line. Deciem is such a quality company. P.S. I have been on the hunt for a new and effective moisturiser, a one and done type product for busy or lazy/unwell days, so I followed your lead and ordered the Dr. CI: LABO aqua collagen gel and what a surprise, not, like most things you enjoy I too enjoy. My skin really likes it, my wallet not so much, but I think it’s worth the price tag, especially the bigger jar with 120mls. Thank you for your years of excellent & experienced recommendations. You always bring a smile to my face, no matter the day I’m having. Never stop shining or educating!

[@littlelilacbunny]

Renee what do you think about the Medik8 and allies of skin peptide serums? ❤❤

[@awetewtewtewawetwetw500]

Can you make another video on supplements ? Do you take verisol collagen

[@noralynpropps2327]

very informative video. thank you. would you please recommend a japanese brand eye cream that helps with dark under eyes? thank you.

[@paolacarallo227]

That's great. Can you layer more than one serum and in which order would you put them on? Thanks x

[@marcelal.6156]

Can you make a video on how to layer everything? Tks

[@PinCushionQueen]

Thinnest to thickest formula is the general rule of thumb. Water based formulations first and then oil based last. Hope that helps.

[@twinietwin]

How about the Timeless peptide serums?

[@laurajones4457]

Hi Renee, Thank you for the video. I was planning to order some products from the brand Alumier. What are your thoughts on this brand and is there certain products you would recommend? Thanks kindly. (I’m 35 so I’m looking to order a full skincare line to help with anti aging) Xo :)

[@carolyngambill283]

Awesome info but exactly WHEN are you supposed to incorporate one, some or all into the skincare routine?

[@dianalepan702]

Hi there love your video. Could you please tell me can I mix retinol abd and peptide serum together thanks

[@maricelajimenez2074]

Hi Renee Do you perhaps know if the argireline serum/gel are safe for pregnant mothers?

[@linel4540]

Thank you for the great video. One question, would you use Niod + PC or Niod + Dr Ci together? I am a little confused on what I should be getting. My main concern would be on the elasticity of the skin (not sure if this is how you say it in English) being 60.

[@kelso7215]

Hi Renee! Do you typically layer your peptide products (using them together in combination), or do you tend to use one at a time depending on how you skin is feeling/looking that day? Thank you for your knowledge and insight :)

[@bhumimandera2515]

Wana know this too ..

[@sandymacisaac6357]

WOW! you talk really fast!😊

[@nushinspace]

how should you store peptide products? should you put them in the fridge? store them away from light? room temp?

[@NaturalWorld253]

I love my Drunk Elephant Protini, I love the no fragrance and no unnecessary ingredients that could be reactive to my skin but have no skin care benefits. They also have the Protini serum which I also like but the original cream formula is more hydrating. I also love the Drunk Elephant packaging. I have actually taken apart empty drunk elephant containers and refilled them with other products I like but are in tubes or open tubs. It works great and the product is kept sealed without being exposed to the air or contamination from touching the product.

[@afroditi5845]

Could we use copper peptides and growth factors simultaneously?

[@angelapellino885]

Thank you! I how the Niod serum is in “conflict” with vitamin C and retinoids, could you suggest how to incorporate this serum? A vitamin C serum with incapsulated vitamin C would be ok? Thanks!

[@CurlyNicky]

I’ve often wondered if collagen-boosting peptides are necessary if someone is already using Retin-A. Don’t retinoids stimulate the production of collagen too?

[@gothamista]

Yes, retinoids do as well as ascorbic acid. I believe it depends on age and what your skin personally needs. I alternate my tretinoin and copper peptides every other night or during periods when I'm not using tret, I'll replace it with the copper peptides. As I get along though, I'm beginning to feel about collagen boosting formulas the same way as antioxidant ones, can't get enough!

[@marielquinonez5300]

Hello Renee, have you tried any products from the brand Stratia? I'm curious to hear your thoughts. Thanks!!

[@gothamista]

I love stratia, their liquid gold moisturizer was always in my favourites and still would be. Love their C + C, truly their formulas are so good and I trust them!

[@orozcoaj69]

Hello Renee, Do you use peptides with vitamin C and Tretinoin? If yes, when do you apply it? Thanks ☺️

[@guisellalosa7557]

I'd use tretinoin with peptides, and then separately vitamin c.

[@rodneuer4600]

Which one would you say it’s the best for normal Acne prone skin? Thanks!

[@bibimbap5917]

Can you use peptides with tretinion or vitamin c?

[@anuszkap24]

Hello, can I use CAIS3 and vitaminC at the same time? For example in my morning routine?

[@hoyeonist]

at which age would you recommend introducing peptides into your skincare routine?

[@TiaVaylik]

Can copper peptides be used with tretinoin?

[@bibimbap5917]

At what age should one start incorporating peptides in their skincare? Is the Late 20s too early?

[@hinabokhari7520]

Is Depology matrixyl better than the ordinary's?

[@mikegan9382]

Peptides is the only reason why i use La Prairie Platinum range

[@sonsoftheedelweiss72]

Do powered peptides work? If which ones? Where to get peptides?

[@susanan5435]

So…which one do I use?? All of them??

[@cristinitaandco]

Wich of this can be used eith Tretinoin? I have heard that some cannot be paired with Vitamin C right?

[@sharonjohn9430]

Thanks for the video. I just checked the prices of PCA and the Japanese one and almost had a heart attack🤪

[@ArticBlueFox96]

I am curious what you think about Decapeptide-52 (OS-1). It is a peptide I am excited for, but unfortunately the only brand that sells products with it, prices their products too high for me.

[@gothamista]

Don't worry I'm investigating one skin, it's a very new peptide and as always am approaching with a side eye haha! Meanwhile keeping the same eye out for it popping up in less expensive formulas!

[@TheEagleslover]

Hey Renee. My favorite topic because these lines are very disrespectful and I’m not quite ready for Botox.

[@aamugirl]

Argireline breaks me out. I've tried the Ordinary Argireline and Buffet with Copper Peptides. They both irritate my skin. 😢

[@CherylBerryl]

Thank you! I have been thinking about this exact topic of late, & have been so confused. Now I have more to go on when comparing different products. I have been using Derma-E Peptides & Flora Collagen. And Biossance Copper Peptides. I was looking into The Ordinary Buffet w/ Copper Peptides, but I was under the impression that you shouldn't use copper peptides along with Vit-C, is that true? Or just the L-Ascorbic Acid type? My skin can't handle that, so I use a derirative of C. Could you please address what goes with what, & what you definitely should not mix together at the same time? Thanks.

[@michellekelly2937]

You shouldn't use Copper Peptides with Vitamin C. I use the NIOD Copper Peptide serum, and they (Deciem) advise that you not use it with Vitamin C. If you go to their website, they give a list of "Conflict" ingredients/products that shouldn't be used with Copper. There are several.

[@gothamista]

Copper peptides are only a concern with ascorbic acid. I don't worry about using alongside C derivatives so you should be fine! Also, if you like the Biossance, I personally think the Ordinary Buffet + Copper peptides is better. Other, non-copper peptides work well with everything and anything.

[@nicoeeek.7181]

Thank you for taking the time to answer these comments, super helpful!!!@@gothamista

[@cashelgawinandthefamily1071]

Have you tried the peptide products from Depology!? I wonder what you think about them !?

[@martinalast8317]

Curious as well

[@faas6679]

Thank you; very informative as always! I have gone through about 3-4 bottles of the PCA exlinea Pro, as I use as L’ Ascorbic and CoQ10 serums in AM so wanted non - copper. I use it am and pm on forehead and around mouth and eyes and I am “ very mature”! It is pricey but I ran out about a month ago and I notice my lines more! I had stopped Botox 15 mos ago to test it, and I have to say it works. I am going to look into the moisturizer you suggest also!

[@MS-sg5vf]

Hi! U noticed more lines after discontinue , Is that what u r trying to convey?...am a little confused..

[@faas6679]

Hi, I am saying the PCA works to smooth out lines as when I stopped for a month, my lines were noticeable and I went back on it.

[@MS-sg5vf]

@faas6679 ok, that means have to use life long..no permanent solution....thank u for sharing.

[@faas6679]

Nothing is permanent- not even Botox or a face lift! It is like anything, if you were to stop using moisturizer, your face would show the wrinkles that were previously plumped up and looked less noticeable, or if you stopped actives such as vitamin c or retinol, your skin would start showing issues again- consistency is key with any skincare, you can’t just stop and think your face won’t show it…. Hope that clears it up- find the routine that works for you and stick with it!

[@MS-sg5vf]

@faas6679 thank you so much...I haven't had any skin routine till now...want to start. ..started with researching....

[@ajitabhkumar3955]

Hi ma'am please suggest peptide night cream.m beginner and m 39yrs old

[@reenakazmann9183]

Can you use two different types of Peptides in the same application? Say the Ordinary multi-peptides + copper peptides and an enzyme prohibitor peptide in the a.m. or would you need to use one in the a.m. and the other in the p.m.? Or does it matter? Thanks.

[@gothamista]

Yes I would use both in the same routine, such as the Re: Pigment followed by the multi peptides + copper - ordered in that way because of texture. RP is super lightweight!

[@hinabokhari7520]

Are peptides enough for people that can't tolerate harsh ingredients like retinoids or vit c?😊

[@Meg_I_am]

Same question.

[@paolacarallo227]

Which ones would you recommend for saggy jaw and cheek? Thanks

[@carolmaplesden916]

same lol

[@nkurdy288]

Very informative, thank u! I wonder where Drunk Elephant’s Proteini Peptide sits in the peptide world 🤔

[@grespinosa]

Love that product, unfortunately can only afford to splurge on the sample size every great once in a while. 🙁😔

[@sivaaruna3062]

Does cosrx snail mucin is safe during pregnancy and breastfeeding

[@PinCushionQueen]

Yes it’s safe.

[@aarontheabc]

💙💙💙

[@iristao8557]

What do you think about the popular Drunk Elephant Protini? What categories of peptides does it have? Really curious to what you think it does for the skin. Thanks!! Would even love a part 2 from you on peptide product reviews.

[@gothamista]

Hi love! Protini uses signal peptides and also lactic acid so it's an exfoliating serum. I prefer to use my peptide serum and exfoliate separately since my skin is too sensitive for daily exfoliation! And yes, there are so many serums to go through would love to do a part 2

[@iristao8557]

Thank you for taking the time to respond! I am on a skin care journey after having 2 babies and love your content style! Looking forward to your future videos!

[@HereDiianas]

​​@@gothamistaHi, actually the amount of Lactic acid in protini is very low which means that it's not acting like an exfoliating but like a moisturizing ingredient. The same ingredient can have different properties depending of its concentration in a product.

[@BartekKowalski-qi4rj]

👍👍👍

[@bernicehamlyn6975]

Maybe i just dont get it but still have no idea which peptides to use for anti-aging

[@PinCushionQueen]

They all have their uses and benefits. I use multiple and my skin really responds well to a combination.

[@heatherpalmer2257]

I heard these products are good for Roseasha. Let me know if you know the best one. My skin is a disaster. ❤❤❤

[@gothamista]

copper peptides and signal peptides are great (i'm rosacea prone). I would try the ordinary multi peptide + copper peptide serum! it's got it all!

[@heatherpalmer2257]

Thank you!❤

[@EmteeTeee]

I have to tell you. You have the most sweetest, most beautiful face :) Gorgeous! Mary :)

[@luke184lisa]

I LOVE PEPTIDES❣️❣️❣️❣️❣️❣️❣️❣️❣️

[@jayadama1301]

What is Peptides?

[@awetewtewtewawetwetw500]

Have you tried one skin?? They say it’s the best peptide

[@gothamista]

Yes am investigating the OS-1, but since it's so new, am approaching with a side eye!

[@awetewtewtewawetwetw500]

I started using it and it works so I didn’t repurchase the niod copper peptide. I have. My skincare budget and I can’t justify buying 2 expensive peptide products

[@nilos21k]

you need to show in a 70 years old face,,

[@amber9761]

Haven't watched her videos in a couple years as I got distracted from skincare, but a bit disappointed on coming back now to see that she's had fillers - looks like cheek fillers

[@gothamista]

Hi and thank you for coming back! I've spoken about my personal reluctance to having work done on my face. I've never had and currently don't have filler, botox, any injectable or surgery. My face however does tend to get puffy especially cheeks and eyes from hormonal imbalances.

[@angelapellino885]

such a disrespectful comment, and even if she had, what you be the issue?

[@F.R.F937]

You should try to get your hand on the Nooance 2% Copper Peptides and the Theramid 3% Copper Peptides, would love to see a review from you 🖤🩶